XLOC_010571 (c4b)



Basic Information


Item Value
gene id XLOC_010571
gene name c4b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 16665203 ~ 16701718 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00020714
ATCTGCAAACACAAGACTTACCATGGAGGAGCAAATTCGTCCTCTTCTCTATCTGCTGCTCTGCATGAGCTGTGCTGTTCAAGGAAATAGCAATCAGAGATTCCTCATCACTGCTCCGAGTGTGTTTCATGTTGGTGTGAAAGAACCTATAGTGATTCAGGTCGGGGAGGCACTGGTCGGCAAACCCGTGTCCTGTCAGTTAGAAACAGAGACGCGGGTTCCCATGTCCGCAAAGGAAACCAAAACAATACACCAAAAAGGAAAGTTTGAGACAGTGAATCTTGAGaTATTTGCAAATACAGTTTCAAACCTGAAGTCAATCAATGGAGAGCCTCCTTATCTAAATCTGGCATGTGAGGTTGATGGTCAGAGACAGCAGACGCGTGTTCTGGTCTCCAAACACAATGGCTACATCTTTATTCAGACGGACCAACCCATATACAACCCCACACAGAAAGTTCGATTCAGAATCTTCACTCTTGATCACTCCATGCGACCAAAATTAGAGATGTATGTTTATGTCTCTATATAtAATGCTGATGGGAACAAGGTCAAGAAGTCAAAGTACAGAGTGTTGGATGGCATCCTGTCAAAAGACTACAAAATTCCTGATGTTTCCAAACCTGGTGTATGGAAGATTACAGCACATTATGAAGATGATGTGGACAATGCAGCGGTGCGCGAATTTAAAGTCCAGAAGTTTGTTCTTCCCAGCTTTGGTGTTTCAGTTCACTCAGAGAAAGCCTTTCTGCAAGCAAATGCTAAGACATTAACATTCACTATTCAGGCCTCATATTCCTATGGAAAGACCATTGATGGTGGTTTCCACTGTCGGTTTGGGATAAAAAAAGGCAAGTCAGAGAATGATCCTGAAATTGAGTTCATCAAGGGGTTGGAAAAAACTGGATCTGTGAAAGAAGGCCTTGCAAAGATAACAGTCAACATTTCAGACATCACCCAAAAACTGGACACAGCATTAGAAGAACTGGCAACAACTCAGACCCAATTCTACATTTCTGCCACAGTGACGGATATTTTAAGTGGTGAGGTACAGGAATCTGAAACCTTCCTTCCTGTTGTTTTGAGTCGGTACAATGTGGATCTGTCTCGGACAAGACTGTTCTACACACCTGCATTTCCTTTACAAGCAGTGGTCACAGTTCGTCACCCAAATGGTTCTCCTGCTGAAGGCGTTCAAGTTAAATTAGATGTCTCGAACTCTAAAGAAAAGTCTACAATTGTTACTACTAATAAAGAAGGAATCGCATTTTACAGCTTCAACCTAGACGGAAAACCACCTTCAGTTTTAGTGCAGGCAACTGTGGATAATGCCAAGTCAATAAGAGCTGTGCATCCGATGAAATCCACAAGCTTCCTTTATATGAGTGTGACAAATAAAGTCTTATCATCAGGACAGTTTCTGGAAGTCTCATTTTACCCCAAAGGTAATCCAGAAGATGGGCAAATATATTATATGATTGTCAGCAGAGGTATGTTGAGATCAACAGGCTCTGTTGCATCAGGTTCTGAAGTAAAAAAATCCATCCAAATACACCCAAACATGACCCCATCCTTCAGATTGATTGCTTTTTACTATATCAAAGAGGGTGACATCATCGCTGATTCTGTATGGGTAGACGTAGAGGACACTTGTGATGGAGagTTTGAGGTAAAACTGCATCATAATTATGGCAATCATAATTATGAACCTGAAAGCACAGCTGAGCTTGACATTGATGTAGGACAACAGAAAAATGCAAAAGTAGCCTTACAAGTTGTGGACAAAGCCATTTACGCCTTGGGGGCTCAAAACAAACTCACCCAGAAACAGGTGTTTGCCTCTATGAAGTCTTATGATCTGGGGTGTTCTTATGGCGGTGGTGAGAATACAGCAGCTGTTTTTAACGATGCTGGCCTGGCCTTCATCTCTCACTCCACCACGATTCGTTCAGCGATGAGAAAAGGTTTCAGCTGTGAGTCTGGTTTTAGACGCAACAAACGTGAGATTGATGTTCAAGCAGAAATGGCAAGAAAAGAGGCTGCGTTTAAGAAAACAGAATTACAGAAATGCTGTCGCCATGGATTCACCCTGATTCCTATGAAGTTTACTTGCGACGAACGAGCAAAAAGAGTGAGCAAAACCGAAAGCAAAGACTGTGTGAATGCCTTCAGAGAGTGCTGTGAGTTTGCAACAAAGCTGAGAGACAAAAAGAGGAGAGAAGACATGAGGACAGGACATGGCAGAActaTTAATTCTAATGAAGTTGAGGAATTTTTTGACTTTGAAATACAAAACATTCGTCATTATTTCCCTCCAAGCTTTGAGTTCAAACAGATTGACGTGAAAGGAAAGGTTAGGCACAGAATCCATTTACCCCATTCTATCACAACATGGGAGATCCAGGCTCTCAGCTTATCTCCATCTCATGGTTTCTGTGTGGCAGAGCCTGTTGACCTCACTGCATTTAAGCCTGTGTTTATTTCTCTGAGGCTTCCCTATTCAGTCAAGCGCTATGAGCAACTGTCTATAGTTGCAGTGATCTTTAATTATGGCAAAATGGAAATGGAGCTTGTTGTGCGCATGCGACAAGTGGATGGTCTTTGTTCACCCGGGTCAGCAACGTCATCATCTTCCGTCAGATTCAGCCTGAAACCAGCATCTTCTCAAACTGTTACTTTCCCTGCTGTCCCCATGGTAAAAGGCGAAATCCCTATCACTATTGCAATCTATGATATTGAAGAAAAAATTGAAGTGGATGCTATTCAAAAGATACTCTTGGTCAAGAACGAGGGAGTGGAAATGAGAGAAGAGCTGACTTATTTGATTAATCTAGATGGCAGAAGTGATCACCGCTTATCCATCAATGGATTTTTCCCTAACAACACTGTTCCTGAAACTGATGTTAATCTATTTGTCAAACTAGAAGAGGAAATATTTGCCCAGTCCACTGCAGTTCCATTACTTTCATCATCCAAAGTGGAAAATCTGATCCAAGCACCTAAAGGCTGTGGAGAACAGACTATGATCTTTATGTCTCCCACTGCCTTGTCAATCCGTTACCTGGATAAAAGTCAGCGCTGGCTGGAACTAGAAGCAGGATCCAGAGACAAAGCACTGGATTTCATTGAGCAAGCTTATGAAcgaattttaacatttaaaaagacgGATGGATCCTATGGAGCTTGGATACAGACTCCGACAAGCACCTGGTTGACTGCACTAGTAGTGAAAGTATTGTCTCTTGTGGCTGAACGACAAATAGAGACTCGTCAACAACATGGAACAACAGAAAGGATGATTTCACAGGAGGACATCCGTCAAGCAGTTACATATTTGATTAAGACACAGAGATCAGATGGGTCCTTTACTGATGCTCATCCAGTCTATCACAGAGAAATGCAGGGAGGAATTGGAGGAGTTGAGCAAGATGCTTCTTTAACAGCTTTCATCACAATAGCTCTCTGTCGCTCTATGCCTTTCTTGGACCAAGAAGCAACTGCTGTGAGCCAAAGCATCGCTCGTGCCACCAACTTCCTGCTAAAACGGGTTGATAATCTTAAAAGGCCTTATGCATTAGCCATTACAGCATACTGTTTGTCTACCTGCCTCACTGAACGAACCCAAGCACTGTCAGCCTGGAAGAAACTCCAAAGTCTCGGAAAACCAGAGGGAGACTGTCTTGTGTGgcaagatgatgatgatgtgcgACTGGTAAATGAAGCGAAATCTAACCGTGTGCCGCATAGAGTGGCATTAAAAGTAGAGACCACCGCATATGCTCTCCTGACTGCGCTGGCACATAGCGACTTAAAAACAGCACAGTCTGCAGTCTGCTTCTTGTCTTCTCAAGAGAACTATGAAGGAGGTTTCAAATCAACACAGGACACTATCGTAGCTTTGGAAGCTCTCTCAGAATATGCATTGAGTTTACCAGAAACCCCCATCACCACAATCAATGCACAGTTTACTGTTACCGGAAGGTCTGAGATGGAGAAGATGAATTTGGAAAAGAGCGAAAATAAAGTGGAAGCAGAGTTAAAAAGACTAGTGGGACAGGAAATAAATGTCAATCTTTCTGGAAAAGGAAAAGCTAAAATGAAGGTGGCAAAGGCTTATTATACTCTCAAGGAAGACGGCAACTGTGCTGATTTGTCAATAAATGTGACTGTAGTAGGAAAAGTGGAATACACATCTGTAGTACAAGAAGATTATAATTACTATGAAGACTATGGGCAGGCCGAAGAGACGAACGAGGAGGAAGATCTCCCTCGGTCAGCCATCGAGTGGTTTGATGCTCGCAGCAGACAAAAAAGAGAGACTTCGAAAAACACGAAGGAGGATGTGGTCTATACAGTGTGTGTCAGTCACACACAGGGGAGGAAGCTCTCTGGAATGGCCATTGCTGATATTACTCTACTTAGTGGTTTTGAGGCAATCAATACAGATCTGGAAAAGCTGAAAGGCCTGGTGGACAAATATATTTCTCACTATGAGGTCACACGTGGAAGAGTACTGTTGTATTTCAATGAGATAGATGGAGGTGAAGCCTGTATTGCATTTGGAGCTGAGCAAAGTGTGCCCATTGGTTTAGTTCAACCTGCTCCTGCTTTGTTTTATGATTACTATGAACCAGACAGGAGATGTTCAGTGTTGTACAGCGCCCCCAAGAGGAGCAAGATGGTTTCCGTCCTGTGCTCAGATGACGTGTGTCAATGTGCAGAAAGAGGTTGTTTCACAGAGAAGAAAACCATTGAGATGGAAATCACCAAAACTGATAGATTTGATTATGCTTGTTACCATTCCAACACCGACTATGCATTTGAAGTCACTGTGAATTCAGTAACCGAAGAGagcaattttatattatattcaacATCTGTGAACGTGGTTCTCCGAAATACGGGAGACTTGAGTGTGAGTCCAGAGAACACACGAGTGTTTGCCAAGAGAAAGCACTGCAAGGGTGAGCTGAAACAGGGTGAGAGGTACCTTATCATGGGCAATGATGGCCCCACCAAAGACTCAAGTGGAAACATGCAGTATCTGCTGGATTCTAAGACATGGGTTGAACAGAAGCTGTCAAAATCAGTATGCCAAGCCTCAGTCAAGAGAAAGTACTGCAAAGAACTGAATGACTTTTTGAAAGAGTACCAAGTTAATGGATGCAATCTGTAGGCAGTACTGCAATTTGTAATATCTCCCATGTAATGTAATATCTCAACATCATTACAGCAGAAATCTACATTTATCCTGAATTGTAAAGTTGCTTGCTGTGGATTTCAATAAGACATACTGTCCTGTCTGTCACAATTTTCTCAAATAAATGTGCTTAATAAGA
>TCONS_00020715
TTGATTATGCTTGTTACCATTCCAACACCGACTATGCATTTGAAGTCACTGTGAATTCAGTAACCGAAGAGagcaattttatattatattcaacATCTGTGAACGTGGTTCTCCGAAATAGTGAGTaatttttctctctctgtctctttgtgaagtttatttattaaccaatttcgagaggatcacgtgcttacgATTGCTTGCTGAGTGGCCATTAATACCCTAAGTCACAcatgacagccatcttcattttaaagaatccctccttccacctctactcctcctTTCTTTTCCTTGatatggtggcacagtggcccaggggttagcactattgcctcacagaaagaacgtcactggttctagtccttaccaagccagccaatgtttctgtgctgagtttacaCATTCTTCCGCGCTCACTTGGGTTTCCCCTGGtctccccggtttcctcccaccattcaaaaacatgcaacttaagttaattgacttatCAAAAtaggcaccatagacatgcacctagtaagtagttatctcttaagagcaatcactatctgttcattagctactacagcaggggagttttcgagatctacctgagttcaaactcccctcttgccttgcaaacgagagggagcttcaggctcgaggatcttatgagctcagcatgccaaacaagctgtataatcaatcatcagctaagtgtgaactttcaATACAAACTTTCAATACACTTTTTAGCGATGATGTAAAACGAATTCTG
>TCONS_00020716
TTTGAGGTAAAACTGCATCATAATTATGGCAATCATAATTATGAACCTGAAAGCACAGCTGAGCTTGACATTGATGTAGGACAACAGAAAAATGCAAAAGTAGCCTTACAAGTTGTGGACAAAGCCATTTACGCCTTGGGGGCTCAAAACAAACTCACCCAGAAACAGGTGTTTGCCTCTATGAAGTCTTATGATCTGGGGTGTTCTTATGGCGGTGGTGAGAATACAGCAGCTGTTTTTAACGATGCTGGCCTGGCCTTCATCTCTCACTCCACCACGATTCGTTCAGCGATGAGAAAAGCTTGTTGTGCGCATGCGACAAGTGGATGGTCTTTGTTCACCCGGGTCAGCAACGTCATCATCTTCCGTCAGATTCAGCCTGAAACCAGCATCTTCTCAAACTGTTACTTTCCCTGCTGTCCCCATGGTAAAAGGCGAAATCCCTATCACTATTGCAATCTATGATATTGAAGAAAAAATTGAAGTGGATGCTATTCAAAAGATACTCTTGGTCAAGAACGAGGGAGTGGAAATGAGAGAAGAGCTGACTTATTTGATTAATCTAGATGGCAGAAGTGATCACCGCTTATCCATCAATGGATTTTTCCCTAACAACACTGTTCCTGAAACTGATGTTAATCTATTTGTCAAACTAGAAGAGGAAATATTTGCCCAGTCCACTGCAGTTCCATTACTTTCATCATCCAAAGTGGAAAATCTGATCCAAGCACCTAAAGGCTGTGGAGAACAGACTATGATCTTTATGTCTCCCACTGCCTTGTCAATCCGTTACCTGGATAAAAGTCAGCGCTGGCTGGAACTAGAAGCAGGATCCAGAGACAAAGCACTGGATTTCATTGAGCAAG

Function


symbol description
c4b Predicted to enable endopeptidase inhibitor activity. Predicted to be involved in complement activation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune disease (multiple); complement component 4b deficiency; and renal cell carcinoma. Orthologous to human C4B (complement C4B (Chido blood group)).

GO:

id name namespace
GO:0006956 complement activation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0004866 endopeptidase inhibitor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-100805-2 Predicted to enable endopeptidase inhibitor activity. Predicted to be involved in complement activation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune disease (multiple); complement component 4b deficiency; and renal cell carcinoma. Orthologous to human C4B (complement C4B (Chido blood group)).

Ensembl:

ensembl_id ENSDARG00000038424

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00020714 False 5339 mRNA 0.42 41 16665203 16701718
TCONS_00020715 False 760 lncRNA 0.42 2 16665854 16666757
TCONS_00020716 True 866 nonsense_mediated_decay 0.43 6 16677708 16692267

Neighbor


gene id symbol gene type direction distance location
XLOC_010570 tnxba coding downstream 15439 16621242 ~ 16649764 (-)
XLOC_010569 cyp21a2 coding downstream 45306 16605517 ~ 16619897 (-)
XLOC_010568 NA coding downstream 61123 16593349 ~ 16604080 (-)
XLOC_010566 si:ch211-257p13.3 coding downstream 74423 16554687 ~ 16590780 (-)
XLOC_010567 CR848667.3 coding downstream 91673 16573414 ~ 16573530 (-)
XLOC_010572 uts2r3 coding upstream 55501 16757219 ~ 16761164 (-)
XLOC_010573 plekhg6 coding upstream 305371 17007089 ~ 17056630 (-)
XLOC_010574 tnfrsf1a coding upstream 359040 17060758 ~ 17072561 (-)
XLOC_010575 si:dkey-260g12.1 coding upstream 400385 17102103 ~ 17116499 (-)
XLOC_010576 CU861451.1 coding upstream 418346 17120064 ~ 17120186 (-)
XLOC_010626 CR392024.2 misc upstream 4193394 20895112 ~ 20895175 (-)
XLOC_010565 CR848667.2 non-coding downstream 135231 16526975 ~ 16529972 (-)
XLOC_010562 NA non-coding downstream 394768 16266556 ~ 16270435 (-)
XLOC_010554 CT573799.2 non-coding downstream 850702 15813506 ~ 15814501 (-)
XLOC_010582 CR936322.1 non-coding upstream 543190 17244908 ~ 17245047 (-)
XLOC_010583 CR936322.2 non-coding upstream 545504 17247222 ~ 17247363 (-)
XLOC_010592 NA non-coding upstream 1003112 17704830 ~ 17706764 (-)
XLOC_010594 NA non-coding upstream 1121729 17823447 ~ 17824848 (-)

Expression



Co-expression Network