XLOC_010632 (pde11al)


Basic Information

Item Value
gene id XLOC_010632
gene name pde11al
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 21144669 ~ 21185778 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020820
CGATTAAATGTTGAGCAATAAAGTTTACattctatatatttatatctatttgtttcttttttgtggCTTTTTTTTCACTGGAcataaaagaaaaagaacaacGTTCTTTGACTGTGTGCTGTCTGGGCAGTTCAGCTGGAGTGATGAAGAACACAGAGACATGTTCAGGTCTATGCTGATGACGGCGTGTGACTTGGGTGCAGTGACTCGACCATGGGAGATCTCAAAACAGGTGGCTGAACTGGTGACCAGTGAATTCTTTGAACAAGGTGACAGGGAGAGATCGGAGCTGAAGCTGACACCAGCTGCCATTTTTGATCGCAATCGTAAAGATGAGCTTCCTGTGCTTCAGCTGGAATGGATTGATGGAATCTGTAAGCCATTATATGAGGCTCTTGTGAAGCTGAATAGAAAGCTTCAGCCAATGGTAGATGGAATTGATGCCAACCGAAAGAAGTGGGAGGAGCTTTGTCTGTCCTATCAGCAAACAAGGAGAGCCTCTGAATGCAACACAGTAGAGACAGACTCCACCCATGAGCCAGAATCTAGTCAGAGTgaagcaaccaatcagaatgaaggCTCCACCCACGGTGTAGAGCCAAAGCAAACACCAGTAGCCAATTACAAAGAAGGGGCGTGTTGTGGTCATTAAAAGTTGGCTGGCTGAGTAATGAGGACTCTGACAAGTTTACTATGTTTATACATGGAAAAACACATTGTTAATCAACCCTTTTTGTTAAGGGTTGCTTTGAGATTGACAGAATTTctattgaaattaaattaattgtcCACTCCAAAAATGGTCTTTCCCAAACTGTATgaactttcttttttctgtggaAGATAAGATAAAAAGATAGTTCAAATAAAGAAGGCTGCAACC
>TCONS_00020821
ATCGACATGACAACTTTTGATTTTTCCGAGGTGGAGGCATTTTTGGATTGCCATCCGGAGCTTTTTGAGGAATATCTCGTCAGAAAGGGAAAATGTGACAGCCTGAGCAGGTGGCTGAAAGAGCATCAGCCGTCCAAAACCTCTCCGGCGGAGGAGAAACGCGGGGTCGCGAGGGATCCATTCTGGCCCACGAACCCTGATGGATTAAAGCGCAGATCGTCCCACATGGAGCTTCGAAAGAACTTCGCCCGGTCCAAAGCGATGACGGCGCACCGGACCTACGACGAGCACGTCAGTCTCACGGCTCACGAGTCCCAGTCGAGCATGCGGCGGCGCGCGCTCCTGCGGAAAGCCAGTTCGTTACCGCCGACCACCGCGCACATCTTGAGCGCGCTGCTCGAGTCCCGAGTGAACGTGCCTCAATATGCCTCCAGCGCCATTGACTACAAATACCGACTCAAAGAGTCCAACGAAAGGGAGTTCTTCCTTGAGCTGGTTAAGGACATTTCGAACGAACTTGACATGACGAATCTAAGTTACAAGATACTTATCAATGTTTGCATTATGGTGAACGCAGACAGGTGTTCGCTTTTCCTGGTGGAGGGACCTTCTCATAAGAGGACACTCGTGTCCAAGTTTTTTGATGTGCACTCGGGTACTACAGTGCGACCCTCTTCCAGCACTCTTGACTCGAATGAGGTGCAGGTTCCGTGGGGAAAAGGCATCATAGGTTATGTAGCAGAACACGGAGAAACCGTCAACACACCGAACGCATACGAGGACCATCGGTTCAGTGATGAAATTGACAAGCTGACAGGCTATAAGACTCAGTCCATTCTGTGTATGGCCATCCGCAACAGTGACGGTGAAGTCATCGGCGTAGTGCAGGCCATCAACAAGAACCCCAGTGGAACACCATTTACAGAGGACGATGAAAAAGTGCTGCAAATGTATCTGCCATTCTGCGGAATATCGATCTCCAACGCCAAGCTCTTCTCCGAATCCCGCAAGGAGTATGAGAGAAGCAGAGCCCTGCTGGAGGTGGTGAATGATCTGTTTGAGGAGCAGACGGACCTAGAGAAGATAGTGAGGAAGATCATGCAGCGTGCACTGACATTGCTGCAGTGTGAACGTTGCTCAGTGCTTCTGCTGGAAGACATCCACTCCCCAGTAGTAAAGTTCTCCCAGACTTTTGAACTAATGTCTCCACTGTGTAGTGTTGATCGTGATATCAGCATGGAGAAGGTGTCTTGTTCAGACTGGCTGATCAATAACAGCATCGCTGAGTTGGTAGCATCAACCGGGCTGCCAGTTAACATAAGTGACGTGTGTCAGGATCCCCGTTTTGATGCTGAGGCGGATCAGGCTTCTGGTTTTCATATTAGATCAGTTCTATGCGTCCCCATCTGGAATCGGACTCATCAGATTATTGGTGTGGCCCAGATATTAAACCGCTTGGACAGGAAGACATTTAATGATGCAGACCAAAGATTATTTGAGGCATTTGTTATTTTCTGTGGTCTGGGCATTAACAACACAATGATGTATAACCAGGTGAAGAAGACTTGGGCTAAGCAGTCTGTGGCTCTAGATATGTTGTCGTATCATGCTACGTGCTCCAAGGCAGAGGTTGATAGACTAAAGGCTGCTAAGATTCCCCTAAGCAGTGAGCTCGGGATCGATGAGTTCCACTTTAATGACTTTTCACTGGACAACGACGCCATGATCACGGCCTCCCTGCGGATGTTTTTGGAGCTTGGTGTCGTACAGAAATTCAAAATTGATTATGAGGTTCTGTGCCGCTGGCTGCTTACTGTGAGGAAGAACTACCGTACTGTAGCATACCACAACTGGAGGCATGCTTTTAATGTCTCGCAGTGCATGTTTATAATGATCACAACTGCTGCGTTCCAGGAGGTGCTGACCGAAACAGAGACACTTGCACTTATGGTTGGATGTTTCTGCCATGATTTGGACCATCGTGGCACAAATAACGCATTTCAGGCCAAGTCTGGCTCAGCACTGGCACTGCTGTATGGAACATCTGCCACACTTGAGCATCATCATTTCAACCACGCTGTCATGATCCTGCAGAGTGAGGGACACAATATTTTTGCGAATCTGTGCTCCAAGGAATACTGCAACATGATGCAGCTACTGAAACAGGCCATTCTGTCTACAGATCTCACTTTGTATTTCAAaaaaagaacaacGTTCTTTGACTGTGTGCTGTCTGGGCAGTTCAGCTGGAGTGATGAAGAACACAGAGACATGTTCAGGTCTATGCTGATGACGGCGTGTGACTTGGGTGCAGTGACTCGACCATGGGAGATCTCAAAACAGGTGGCTGAACTGGTGACCAGTGAATTCTTTGAACAAGGTGACAGGGAGAGATCGGAGCTGAAGCTGACACCAGCTGCCATTTTTGATCGCAATCGTAAAGATGAGCTTCCTGTGCTTCAGCTGGAATGGATTGATGGAATCTGTAAGCCATTATATGAGGCTCTTGTGAAGCTGAATAGAAAGCTTCAGCCAATGGTAGATGGAATTGATGCCAACCGAAAGAAGTGGGAGGAGCTTTGTCTGTCCTATCAGCAAACAAGGAGAGCCTCTGAATGCAACACAGTAGAGACAGACTCCACCCATGAGCCAGAATCTAGTCAGAGTgaagcaaccaatcagaatgaaggCTCCACCCACGGTGTAGAGCCAAAGCAAACACCAGTAGCCAATTACAAAGAAGGGGCGTGTTGTGGTCATTAAAAGTTGGCTGGCTGAGTAATGAGGACTCTGACAAGTTTACTATGTTTATACATGGAAAAACACATTGTTAATCAACCCTTTTTGTTAAGGGTTGCTTTGAGATTGACAGAATTTctattgaaattaaattaattgtcCACTCCAAAAATGGTCTTTCCCAAACTGTATgaactttcttttttctgtggaAGATAAGATAAAAAGATAGTTCAAATAAAGAAGGCTGCAAC
>TCONS_00020822
GGTGCTGCAAATGTATCTGCCATTCTGCGGAATATCGATCTCCAACGCCAAGCTCTTCTCCGAATCCCGCAAGGAGTATGAGAGAAGCAGAGCCCTGCTGGAGGTGGTGAATGATCTGTTTGAGGAGCAGACGGACCTAGAGAAGATAGTGAGGAAGATCATGCAGCGTGCACTGACATTGCTGCAGTGTGAACGTTGCTCAGTGCTTCTGCTGGAAGACATCCACTCCCCAGTAGTAAAGTTCTCCCAGACTTTTGAACTAATGTCTCCACTGTGTAGTGTTGATCGTGATATCAGCATGGAGAAGGTGTCTTGTTCAGACTGGCTGATCAATAACAGCATCGCTGAGTTGGTAGCATCAACCGGGCTGCCAGTTAACATAAGTGACGTGTGTCAGGATCCCCGTTTTGATGCTGAGGCGGATCAGGCTTCTGGTTTTCATATTAGATCAGTTCTATGCGTCCCCATCTGGAATCGGACTCATCAGATTATTGGTGTGGCCCAGATATTAAACCGCTTGGACAGGAAGACATTTAATGATGCAGACCAAAGATTATTTGAGGCATTTGTTATTTTCTGTGGTCTGGGCATTAACAACACAATGATGTATAACCAGGTGAAGAAGACTTGGGCTAAGCAGTCTGTGGCTCTAGATATGTTGTCGTATCATGCTACGTGCTCCAAGGCAGAGGTTGATAGACTAAAGGGACACAATATTTTTGCGAATCTGTGCTCCAAGGAATACTGCAACATGATGCAGCTACTGAAACAGGCCATTCTGTCTACAGATCTCACTTTGTATTTCAAaaaaagaacaacGTTCTTTGACTGTGTGCTGTCTGGGCAGTTCAGCTGGAGTGATGAAGAACACAGAGACATGTTCAGGTCTATGCTGATGACGGCGTGTGACTTGGGTGCAGTGACTCGACCATGGGAGATCTCAAAACAGGTGGCTGAACTGGTGACCAGTGAATTCTTTGAACAAGGTGACAGGGAGAGATCGGAGCTGAAGCTGACACCAGCTGCCATTTTTGATCGCAATCGTAAAGATGAGCTTCCTGTGCTTCAGCTGGAATGGATTGATGGAATCTGTAAGCCATTATATGAGGCTCTTGTGAAGCTGAATAGAAAGCTTCAGCCAATGGTAGATGGAATTGATGCCAACCGAAAGAAGTGGGAGGAGCTTTGTCTGTCCTATCAGCAAACAAGGAGAGCCTCTGAATGCAACACAGTAGAGACAGACTCCACCCATGAGCCAGAATCTAGTCAGAGTgaagcaaccaatcagaatgaaggCTCCACCCACGGTGTAGAGCCAAAGCAAACACCAGTAGCCAATTACAAAGA

Function

symbol description
pde11al Predicted to enable cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cAMP-mediated signaling; negative regulation of cGMP-mediated signaling; and signal transduction. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Orthologous to human PDE11A (phosphodiesterase 11A).

GO:

id name namespace
GO:0035249 synaptic transmission, glutamatergic biological_process
GO:0065008 regulation of biological quality biological_process
GO:0034220 ion transmembrane transport biological_process
GO:0007267 cell-cell signaling biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0097120 receptor localization to synapse biological_process
GO:1900271 regulation of long-term synaptic potentiation biological_process
GO:0099177 regulation of trans-synaptic signaling biological_process
GO:0098916 anterograde trans-synaptic signaling biological_process
GO:0043951 negative regulation of cAMP-mediated signaling biological_process
GO:0099509 regulation of presynaptic cytosolic calcium ion concentration biological_process
GO:0010754 negative regulation of cGMP-mediated signaling biological_process
GO:0055085 transmembrane transport biological_process
GO:0098953 receptor diffusion trapping biological_process
GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping biological_process
GO:0099536 synaptic signaling biological_process
GO:0099537 trans-synaptic signaling biological_process
GO:0050804 modulation of chemical synaptic transmission biological_process
GO:0050806 positive regulation of synaptic transmission biological_process
GO:0006836 neurotransmitter transport biological_process
GO:0035725 sodium ion transmembrane transport biological_process
GO:0007165 signal transduction biological_process
GO:0099628 neurotransmitter receptor diffusion trapping biological_process
GO:0030672 synaptic vesicle membrane cellular_component
GO:0030133 transport vesicle cellular_component
GO:0044456 obsolete synapse part cellular_component
GO:0045202 synapse cellular_component
GO:0012506 vesicle membrane cellular_component
GO:0099501 exocytic vesicle membrane cellular_component
GO:0099503 secretory vesicle cellular_component
GO:0097458 obsolete neuron part cellular_component
GO:0070382 exocytic vesicle cellular_component
GO:0008021 synaptic vesicle cellular_component
GO:0098793 presynapse cellular_component
GO:0030658 transport vesicle membrane cellular_component
GO:0030659 cytoplasmic vesicle membrane cellular_component
GO:0005416 amino acid molecular_function
GO:0015171 amino acid transmembrane transporter activity molecular_function
GO:0015179 L-amino acid transmembrane transporter activity molecular_function
GO:0022804 active transmembrane transporter activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0046873 metal ion transmembrane transporter activity molecular_function
GO:0022857 transmembrane transporter activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0022890 inorganic cation transmembrane transporter activity molecular_function
GO:0015318 inorganic molecular entity transmembrane transporter activity molecular_function
GO:0046943 carboxylic acid transmembrane transporter activity molecular_function
GO:0005215 transporter activity molecular_function
GO:0015075 ion transmembrane transporter activity molecular_function
GO:0015077 monovalent inorganic cation transmembrane transporter activity molecular_function
GO:0008324 cation transmembrane transporter activity molecular_function
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity molecular_function
GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity molecular_function
GO:0005342 organic acid transmembrane transporter activity molecular_function
GO:0008081 phosphoric diester hydrolase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-031118-106 Predicted to enable cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cAMP-mediated signaling; negative regulation of cGMP-mediated signaling; and signal transduction. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Orthologous to human PDE11A (phosphodiesterase 11A).

Ensembl:

ensembl_id ENSDARG00000006151

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020820 False 883 lncRNA 0.41 5 21144669 21146623
TCONS_00020821 False 2993 mRNA 0.48 20 21144670 21185778
TCONS_00020822 True 1347 mRNA 0.47 14 21144922 21181128

Neighbor

gene id symbol gene type direction distance location
XLOC_010631 si:dkey-271j15.3 coding downstream 4571 21131015 ~ 21140098 (-)
XLOC_010630 NA coding downstream 61650 21079589 ~ 21083019 (-)
XLOC_010629 cbx3b coding downstream 96797 21038520 ~ 21047872 (-)
XLOC_010628 snx10b coding downstream 106654 21033633 ~ 21038015 (-)
XLOC_010625 tax1bp1b coding downstream 209162 20805322 ~ 20935507 (-)
XLOC_010633 NA coding upstream 32564 21218342 ~ 21224878 (-)
XLOC_010634 mpp6a coding upstream 256584 21442362 ~ 21489641 (-)
XLOC_010635 BX469919.1 coding upstream 265377 21451155 ~ 21451284 (-)
XLOC_010636 stk31 coding upstream 306113 21491891 ~ 21540077 (-)
XLOC_010637 ddr1 coding upstream 361805 21547583 ~ 21620949 (-)
XLOC_010626 CR392024.2 misc downstream 249494 20895112 ~ 20895175 (-)
XLOC_010627 NA non-coding downstream 217544 20923482 ~ 20927125 (-)
XLOC_010623 CR354600.1 non-coding downstream 750860 20393693 ~ 20393809 (-)
XLOC_010621 NA non-coding downstream 832003 20309370 ~ 20312666 (-)
XLOC_010619 NA non-coding downstream 991944 20149577 ~ 20152725 (-)
XLOC_010643 FP015862.3 non-coding upstream 614607 21800385 ~ 21803111 (-)
XLOC_010645 FP015862.1 non-coding upstream 636956 21822734 ~ 21823249 (-)
XLOC_010647 NA non-coding upstream 650402 21836180 ~ 21836568 (-)

Expression


Co-expression Network