Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_000107 |
| gene name | tlr2 |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007112.7 |
| NCBI id | CM002885.2 |
| chromosome length | 59578282 |
| location | 8984068 ~ 8988504 (+) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| tlr2 | Predicted to enable signaling receptor activity and triacyl lipopeptide binding activity. Acts upstream of or within activation of immune response and immune response. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain; integument; liver; and spleen. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2). |
| id | name | namespace |
|---|---|---|
| GO:0045087 | innate immune response | biological_process |
| GO:0002253 | activation of immune response | biological_process |
| GO:0006954 | inflammatory response | biological_process |
| GO:0050729 | positive regulation of inflammatory response | biological_process |
| GO:0034134 | toll-like receptor 2 signaling pathway | biological_process |
| GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | biological_process |
| GO:0002224 | toll-like receptor signaling pathway | biological_process |
| GO:0007165 | signal transduction | biological_process |
| GO:0002237 | response to molecule of bacterial origin | biological_process |
| GO:0005887 | integral component of plasma membrane | cellular_component |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral component of membrane | cellular_component |
| GO:0038023 | signaling receptor activity | molecular_function |
| GO:0042497 | triacyl lipopeptide binding | molecular_function |
| id | description |
|---|---|
| ko04151 | PI3K-Akt signaling pathway |
| ko04145 | Phagosome |
| ko04613 | Neutrophil extracellular trap formation |
| ko04620 | Toll-like receptor signaling pathway |
| ko05205 | Proteoglycans in cancer |
| ko05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
| ko05170 | Human immunodeficiency virus 1 infection |
| ko05161 | Hepatitis B |
| ko05171 | Coronavirus disease - COVID-19 |
| ko05162 | Measles |
| ko05168 | Herpes simplex virus 1 infection |
| ko05169 | Epstein-Barr virus infection |
| ko05132 | Salmonella infection |
| ko05134 | Legionellosis |
| ko05152 | Tuberculosis |
| ko05146 | Amoebiasis |
| ko05144 | Malaria |
| ko05145 | Toxoplasmosis |
| ko05140 | Leishmaniasis |
| ko05142 | Chagas disease |
| ko05323 | Rheumatoid arthritis |
| ko05321 | Inflammatory bowel disease |
| ko05417 | Lipid and atherosclerosis |
| ko04131 | Membrane trafficking |
| ko04147 | Exosome |
| ko04054 | Pattern recognition receptors |
| ko04090 | CD molecules |
| ko00536 | Glycosaminoglycan binding proteins |
| id | description |
|---|---|
| ZDB-GENE-040219-6 | Predicted to enable signaling receptor activity and triacyl lipopeptide binding activity. Acts upstream of or within activation of immune response and immune response. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain; integument; liver; and spleen. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2). |
| ensembl_id | ENSDARG00000037758 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00000199 | False | 2457 | mRNA | 0.43 | 2 | 8984068 | 8988504 |
| TCONS_00000200 | True | 2367 | mRNA | 0.44 | 1 | 8986138 | 8988504 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_000106 | NA | coding | upstream | 7646 | 8967479 ~ 8976422 (+) |
| XLOC_000105 | NA | coding | upstream | 18129 | 8950874 ~ 8965939 (+) |
| XLOC_000104 | NA | coding | upstream | 281384 | 8694196 ~ 8702684 (+) |
| XLOC_000103 | fscn1b | coding | upstream | 313582 | 8662530 ~ 8670486 (+) |
| XLOC_000102 | SLC29A4 | coding | upstream | 373504 | 8601935 ~ 8610564 (+) |
| XLOC_000108 | prkcba | coding | downstream | 16215 | 9004719 ~ 9064912 (+) |
| XLOC_000109 | BX004779.3 | coding | downstream | 82820 | 9071324 ~ 9074479 (+) |
| XLOC_000110 | cacng3a | coding | downstream | 93913 | 9082417 ~ 9091935 (+) |
| XLOC_000111 | NA | coding | downstream | 140882 | 9129386 ~ 9132490 (+) |
| XLOC_000112 | rasd3 | coding | downstream | 156454 | 9144958 ~ 9145896 (+) |
| XLOC_000100 | NA | non-coding | upstream | 393432 | 8587230 ~ 8590636 (+) |
| XLOC_000098 | AL928650.2 | non-coding | upstream | 406794 | 8575307 ~ 8577274 (+) |
| XLOC_000097 | NA | non-coding | upstream | 409011 | 8573777 ~ 8575057 (+) |
| XLOC_000116 | BX323038.1 | non-coding | downstream | 289342 | 9277846 ~ 9285351 (+) |
| XLOC_000120 | NA | non-coding | downstream | 898451 | 9886955 ~ 9914630 (+) |
| XLOC_000121 | NA | non-coding | downstream | 958160 | 9946664 ~ 9951873 (+) |
| XLOC_000133 | AL935188.1 | non-coding | downstream | 1375216 | 10363720 ~ 10363851 (+) |
