XLOC_010742 (pdp1)


Basic Information

Item Value
gene id XLOC_010742
gene name pdp1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 26816753 ~ 26820634 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00021019
AGGCTCTAGAGATGCAGGCGGGGTGTTAGTGTGTATGAACTCATGTAGTCTGATCAAACACTGACCACAAACTCAGTCGCCCACTGATATCCTCAGGTCCTTCGAGGGTAAAGTCAAATTATTATGGCTGCTACCTCCCAGGTTTTCAGGGTCATCCATGGCAGGAGATTTGGTCAGATCTTTGTGCCAGCCATAACATGCCAAATCTGCATTCAGACTCCTCATCCCTGTTCCAGTGCAGCTCAGACACACATCTCTGATCAAAGATGGCGGTTCCAGTCACGGGGATACAGGACCTCACCTGCAAGGCACACCTACTACCTGACTCCACCTCAGGTTAACAGCATCCTAAAGGCTAATGAGTACAACTTCAAAGTTCCTGAGTTTGATGGCAAGAACCTCAGCTCGGTCATGGGTTTTGACAGTAATCAGCTGCCAGCAAACGCACCCATTGAGGATCGGCGAAGTGCAGCAACGTGCCTCCAAACACGTGGAATGCTTTATGGCGTATTTGATGGCCACGCCGGCTGTGCTTGTGCTCAGGCACTCAGCGAGCGGCTCTTCTATTATATCGCGGTTTCATTGCTCCCACATGAGACATTGATCGAGCTTGAGAACGCAGTGGAGAACGGAAGACCTCTTCACCCCATTCTACAATGGCACAAGCATCCCAACGACTACTTCAGCAAAGAAGCCTCACGCCTTTACTTCTCCAGCCTGCGCACTTACTGGCAGGAGCTCCTGGATCTGAGCGTTCCTGGGGAGCAACCTGAGGTTGCGGAAGCTCTTGTGACTGCCTTTAAAAGGTTGGACAATGACATCTCCCTGGAAGCACAAGTTGGTGACCCAAATGCGTTCTTGCACTACTGGGTGCTTCGTGTGGCATTCTCAGGCGCTACGGCATGTGTTGCACACATTGATGGTAACGAGCTCCATGTTGCCAACACTGGAGATGGACGTGCAGTCCTGGGTGTTCAAGAACCCGATGGCTCTTTTTCTGCTCTCACGCTCACCAATGACCACAATGCGCAGAATGAATCTGAGGTTCAGCGTGTACGGTCAGAGCACCCGCACTCTGAGGCCAAAACTGTTGTGAAGCAGGATCGGCTGTTAGGGTTACTCATGCCATTTCGAGCCTTTGGAGATGTTAAATTCAAGTGGAGCATCGAGCTGCAGCGACGTGTTCTGGAGTCGGGACCGGATCAGCTCCATGAGAATGAGCACGCCAAGTTTATCCCACCCAACTACCACACGCCACCCTACCTTACAGCAGAGCCTGAGGTTACTCGACACCGCCTTCGTCCTCAGGATCGTTTTCTGGTGCTGGGCTCGGACGGGCTGTGGGAAACACTGCACAGGCAGGAGGTGGTGAGGATTGTGGGGGAGCATCTCACCGGGGTGCACCAGCAGCTGCCGGTCAGTGTTGGTGGTTTTAAGGTGACCCTGGGTCAGATGCAGGGATTGTTGCAGGAGAGAAAGGCTCGCATCTCCTCCACCTTTGAGGACCAAAATGCAGCTACACATTTGATTAGGCATGCGGTGGGGAGTAATGAGTTTGGAATGGTGGACCATGAGAGACTGTCAAAGATGTTAAGTTTGCCAGAGGAATTAGCTCGCATGTATAGGGATGATATCACAATTATTATAGTACAGTTTAATCCACACGTCATTGGGGGACAGTAGAACAGGACAGATTGTTCCTCCCACACGCTCTCTGTTACATATATCTTCACTTTTAATCTAACGCACAATCTCGACGCTGCATTATCCACAATATCAGCACAGCAAAACGTTACCTTTTACCAGTGGAATGTATTACTCTTTTATGCTCACTTTTATATTCATGGCAGCTGCCTCAAAGGGGAATCATATCTCAGCTGTGAGCTGTGTTGGATCCTAATGTTATATGTGGAATGAAGCTAAACAGAAAAGGTCATGCTGAGCCCACTACAGAACCGCTTTCACAATTGGTCAAATTGCACCACCAAACCATAAATCAAGATTGGAACTCCTGGTGACATTGACTAATGTAGGTTCAGCTAATTTTGCACTGAGGAGAGATTTGTATAGTA

Function

symbol description
pdp1 Predicted to enable [pyruvate dehydrogenase (lipoamide)] phosphatase activity. Predicted to be involved in positive regulation of pyruvate dehydrogenase activity and protein dephosphorylation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in obesity and pyruvate decarboxylase deficiency. Orthologous to human PDP1 (pyruvate dehydrogenase phosphatase catalytic subunit 1).

GO:

id name namespace
GO:1904184 positive regulation of pyruvate dehydrogenase activity biological_process
GO:0006470 protein dephosphorylation biological_process
GO:0005739 mitochondrion cellular_component
GO:0046872 metal ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0043169 cation binding molecular_function
GO:0003824 catalytic activity molecular_function
GO:0004721 phosphoprotein phosphatase activity molecular_function
GO:0004722 protein serine/threonine phosphatase activity molecular_function
GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity molecular_function
GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060810-70 Predicted to enable [pyruvate dehydrogenase (lipoamide)] phosphatase activity. Predicted to be involved in positive regulation of pyruvate dehydrogenase activity and protein dephosphorylation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in obesity and pyruvate decarboxylase deficiency. Orthologous to human PDP1 (pyruvate dehydrogenase phosphatase catalytic subunit 1).

Ensembl:

ensembl_id ENSDARG00000076308

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00021019 True 2072 mRNA 0.50 2 26816753 26820634

Neighbor

gene id symbol gene type direction distance location
XLOC_010741 BX511010.1 coding downstream 64548 26747753 ~ 26752205 (-)
XLOC_010740 NA coding downstream 84825 26719880 ~ 26731928 (-)
XLOC_010739 esrp1 coding downstream 140068 26645663 ~ 26676685 (-)
XLOC_010738 BX537166.2 coding downstream 174719 26619613 ~ 26642034 (-)
XLOC_010737 CR391910.3 coding downstream 215320 26601000 ~ 26601433 (-)
XLOC_010743 ino80c coding upstream 29847 26850481 ~ 26855945 (-)
XLOC_010744 tmem245 coding upstream 305839 27126473 ~ 27149202 (-)
XLOC_010745 LO017771.1 coding upstream 337049 27157683 ~ 27161410 (-)
XLOC_010746 frrs1l coding upstream 345523 27166157 ~ 27174373 (-)
XLOC_010747 alg2 coding upstream 395304 27215938 ~ 27224246 (-)
XLOC_010626 CR392024.2 misc downstream 5921578 20895112 ~ 20895175 (-)
XLOC_010734 CR391910.2 non-coding downstream 309349 26503093 ~ 26507404 (-)
XLOC_010748 NA non-coding upstream 534784 27355418 ~ 27373866 (-)
XLOC_010752 NA non-coding upstream 774928 27595562 ~ 27598677 (-)
XLOC_010756 NA non-coding upstream 1157332 27977966 ~ 28006936 (-)
XLOC_010767 NA non-coding upstream 2210048 29030682 ~ 29042101 (-)
XLOC_010769 CR938717.1 non-coding upstream 2335104 29155738 ~ 29155852 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_06522009_06523565 PDP1 coding CI01000027 null 6521545 ~ 6523800 (-)