XLOC_000108 (prkcba)


Basic Information

Item Value
gene id XLOC_000108
gene name prkcba
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 9004719 ~ 9064912 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000201
GGCAggcgtgtgcgcgcgcgcgtgccCACCAACAGGGAAGCGAAGCGCAAGTCGAGCAGGACCCCGTACACTAGCGCAGTCTACAAGTCGAGGAGATTTCGACCCACTACATCCATTTCTCCCCTATCATGACCGAGTCATCGGATTCAGATGGCAAGGAGGGCGCGCGGGGATTCGCCAGGCAGGGCGCGCTGAGGCAGAAGAACGTGCACGAAGTGAAGGATCACAAGTTCATCGCGCGCTTCTTCAAGCAGCCGACCTTCTGCAGCCACTGCACCGACTTCATCTGGGGTTTCGGCAAACAAGGCTTCCAGTGTCAAGTGTGCTGTTTTGTGGTTCACAAACGCTGCCATGAGTTTGTTCACTTCTCCTGCCCAGGGTCCGACAAGGGCCCTGCATCAGATGACCCTCGCAAATATCATTCGTTCAAGGTACACACATACACCAGTCCCACATTCTGTGACCACTGTGGATCTCTACTGTACGGCCTCATACACCAAGGGATGAGATGTTTGAATTGTCTGATGAATATTCATAAGCGATGCTTTAAGCATGTTCCCAGCCTGTGTGGAACAGACCACACTGAGAAGAGAGGGAGGCTGCATTTCTCTGCTAGTATCACAGGCAATGTTCTCAGTGTGTCCGtcaAGGAGGCTCGTAACTTGGTGCCAATGGATCCAAGCGGCCTGTCAGATCCATACGTGAAGCTCAAATTAATTCCAGACCCAAAGAGCGAGAGCAAGCAGAAGACCAAAACCATAAAGGGCTGCCTCAATCCGGTCTGGAACGAAGACTTCACCTTTGCCCTCAAAGACACGGATAAAGACAGGCGCCTGTATGTGGAGGTGTGGGATTGGGATCGGGGCACCAGGAATGACTACATGGGCTCCATGTCTTTTGGCATCTCTGAGCTGATGAACCAAAGTGTGGACGGATGGTTTAAGATTCTCGCTTGTGAGGAAGGGGTCTTTTTCAACGTTCCTGTTTATGTAGATGAAGAGGAGGGCAACAAGGAGCTGAGTAAGAGATTTGAGAGAGCCAAGATTGGCCCGGGCACTAATAATACAGATGGCGCTTCAAAAAATGACCTCTCCAAATATGATGCCAATGGCAACCAAGACCGCATGAAGCTCGCAGACTTCAACTTCATCATGGTGCTCGGCAAAGGCAGCTTTGGCAAGGTGATGCTTGCGGAGCGTAAAGGTTCAGACGAGCTGTACGCAGTGAAGATCTTGAAGAAGGACGTGGTGATTCAGGATGATGATGTGGAGTGCACCATGGTGGAGAAGAGAGTTCTGGCTTTGTCTGGAAAACCACCGTTCCTCACGCATCTCCACTCCTGCTTTCAGACGATGGACCGTCTTTACTTCGTGATGGAGTATATCAGCGGTGGAGACCTGATGTTTCAGATACAACAAACGGGAAAGTTTAAGGAGCCCCTCGCTGTGTTCTATGCTGGAGAGATTGCCATTGGCCTGTTCTTTCTTCATTCTAAGGGCATTATTTACAGAGATCTGAAGCTGGATAATGTGATGTTGGACTCTGAAGGCCACATTAAGATTGCAGATTTTGGCATGTGCAAAGAGAACATGTTTGATAAAGACACAACAAAAACCTTCTGTGGCACTCCAGATTACATCGCCccagagATCATTGCATATCAGCCGTATGGAAAGTCTGTTGATTGGTGGGCTTATGGAGTTCTCCTGTATGAAATGCTGGCAGGACAGCCTCCTTTTGATGGTGAGGATGAAGATGAGCTGTTCCAGTCCATCATGGAGCATCACGTGTCTTACCCCAAATCCATGTCCAAAGAAGCAGTCGCCATATGCAAGGGGCTGATGACCAAGCATCCCGGTAAACGTCTGGGCTGTGGACTGGAGGGTGAACGGGACATTAAAGAGCATGCTTTCTTCCGTTTCGTGGACTGGGAAAGACTGCAAAACAAGGAAGTTCAACCTCCATACAAACCCAAATCTTGCGGTCGAGACGCAGGGAACTTTGATCTTTTTTTCACTCGTCATCCTCCAATCCTGACCCCTCCTGACCTGGAAGTGATTCAAAACCTGGACCAAGAGGAATTTCGAGGCTTCTCATACGTTAATACAAAATTTGCATCGATGAAATCCAAGTAGCCAGTTTTAGCCAAGCACAATATATATAGGGACCAATGAGATTATAGATACTGAAATGACAGAGTTTGAATGAGCCAATGAGAGTTTGACCTGACTGTTGGAGGAACGGAGGTAATTTCTATATCTATATTGTTCTTCCTTATTATTTCTGGTTTGATTTAAAAAGGATAAAGGGAAGAGATTAAAGGAACTTGTAAATGAACTTACAAAGAGTTAGTGTGTAGCAAGATTTGGACTGTATACTTGTATATCATAGACTGTAGtctaaaaacaacaactaaagtatCTGGGTGACTCTAGTGTCCAAGTCACATTTCACCCAATATTAAAAATAGAGATATAAAAA
>TCONS_00000202
AGGGAAGCGAAGCGCAAGTCGAGCAGGACCCCGTACACTAGCGCAGTCTACAAGTCGAGGAGATTTCGACCCACTACATCCATTTCTCCCCTATCATGACCGAGTCATCGGATTCAGATGGCAAGGAGGGCGCGCGGGGATTCGCCAGGCAGGGCGCGCTGAGGCAGAAGAACGTGCACGAAGTGAAGGATCACAAGTTCATCGCGCGCTTCTTCAAGCAGCCGACCTTCTGCAGCCACTGCACCGACTTCATCTGGGGTTTCGGCAAACAAGGCTTCCAGTGTCAAGTGTGCTGTTTTGTGGTTCACAAACGCTGCCATGAGTTTGTTCACTTCTCCTGCCCAGGGTCCGACAAGGGCCCTGCATCAGATGACCCTCGCAAATATCATTCGTTCAAGGTACACACATACACCAGTCCCACATTCTGTGACCACTGTGGATCTCTACTGTACGGCCTCATACACCAAGGGATGAGATGTTTGAATTGTCTGATGAATATTCATAAGCGATGCTTTAAGCATGTTCCCAGCCTGTGTGGAACAGACCACACTGAGAAGAGAGGGAGGCTGCATTTCTCTGCTAGTATCACAGGCAATGTTCTCAGTGTGTCCGTTAAAGATAAGTaaattttggttgaactatccatttaaactGCAGTGACCATTACTATCACGTTAGCATATGTGTGTAAACGGTAATACTTTActataaggtttattagttaatgttaattaatgcatttactaatgtgcccaaacattgaacaatacatttactacagttttTATTCATGGTAGATACTGCagcagttgttcattgttagttcatgttaactcacagtgcattaactaatgttaacaagcatgtacTTGGATGcttataatgcattagtaaatgttcaattatgattaataaatgctgtacaagtgttgttcatgattagttcatgttagtaaatgcattaactaaggaaccttattgtaaagggtTACCGTGTAAAAATATAGTAGGGCTAAAcattatattgtttcagcattgatatcgcgatgtgcgcatccgcaaaTTTCAAagcgcaaagatatgcaatgtccagtctgaattacagttgaccaggagctacagaattgtatttatatggaaatatatggtttatgc

Function

symbol description
prkcba Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm and membrane. Is expressed in several structures, including brain; forebrain neural keel; otic placode; pectoral fin musculature; and pronephros. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta).

GO:

id name namespace
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004697 protein kinase C activity molecular_function
GO:0004698 calcium-dependent protein kinase C activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1354 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm and membrane. Is expressed in several structures, including brain; forebrain neural keel; otic placode; pectoral fin musculature; and pronephros. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta).

Ensembl:

ensembl_id ENSDARG00000008723

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000201 False 2481 mRNA 0.47 17 9004719 9064912
TCONS_00000202 True 1155 mRNA 0.43 6 9004752 9044347

Neighbor

gene id symbol gene type direction distance location
XLOC_000107 tlr2 coding upstream 16215 8984068 ~ 8988504 (+)
XLOC_000106 NA coding upstream 28297 8967479 ~ 8976422 (+)
XLOC_000105 NA coding upstream 38780 8950874 ~ 8965939 (+)
XLOC_000104 NA coding upstream 302035 8694196 ~ 8702684 (+)
XLOC_000103 fscn1b coding upstream 334233 8662530 ~ 8670486 (+)
XLOC_000109 BX004779.3 coding downstream 6412 9071324 ~ 9074479 (+)
XLOC_000110 cacng3a coding downstream 17505 9082417 ~ 9091935 (+)
XLOC_000111 NA coding downstream 64474 9129386 ~ 9132490 (+)
XLOC_000112 rasd3 coding downstream 80046 9144958 ~ 9145896 (+)
XLOC_000113 plk1 coding downstream 88229 9153141 ~ 9161843 (+)
XLOC_000100 NA non-coding upstream 414083 8587230 ~ 8590636 (+)
XLOC_000098 AL928650.2 non-coding upstream 427445 8575307 ~ 8577274 (+)
XLOC_000097 NA non-coding upstream 429662 8573777 ~ 8575057 (+)
XLOC_000116 BX323038.1 non-coding downstream 212934 9277846 ~ 9285351 (+)
XLOC_000120 NA non-coding downstream 822043 9886955 ~ 9914630 (+)
XLOC_000121 NA non-coding downstream 881752 9946664 ~ 9951873 (+)
XLOC_000133 AL935188.1 non-coding downstream 1298808 10363720 ~ 10363851 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00018470 NA coding CM030135.1 CM030135.1 11677762 ~ 11678127 (+)