XLOC_010846 (usp45)


Basic Information

Item Value
gene id XLOC_010846
gene name usp45
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 32676517 ~ 32727199 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00021223
GACCACGTGACACATCTGATACTTGTGCTTTCTGTTCTTCCCTAAATGCCAGTAAATACGCCGAATAACTCTCTTAATCAAAACCGTAACTGCATCTCGGGATTTTTCGATTAATGAATGTCGAAGTGTTAGACGCGAACGCCAAACCCCCGACAGGAATTCCTCCGTGTTTGTTCTAAAGTTGTGAGCATATGTAAGTTGTCAGGCTCGCTCTTCTTCCACCTGGACACTTGACAACTGACGTTCACTTGGTTGCGAGCCTGGAGAGGAGGAGAACATAAACAGGATACCAATGCGGTTGAAAGACCCCTTCTCTTTAAAAACCGCAGACATGACCAAGCGGTCTAACAAGCCAAAAAAACCTCGCGATGAAGACTCATCTGACGAGGTTGGCGGTCTGACGTGCCAGCATGTGAGCAGAGCTGTGGACCTGAGCTCAGTAAAGAAGGCAGTGACGGGCAGCCTGTGGTCTGTGTGCTCTGACTGCCTTAAAGAGAGGAACGTGCTGGAGGGAGAAACGGCAGGAGCACATGACATCCTTGTGTGCCTCAAGTGTGGCTTCCAGGGCTGCAACCAAGCAGAAGTTCAGCATTCCACAAAACACCAGCAAGCTCATCACTCAGACTCTCACTGTATCACCATCAGCCTCACTACATGGAAGGCCTGGTGCTTTGAATGTAAGGAAGAGCTGTCCACTCACTGCAATAAGAAAGCATTGGCTCAGACTCTGGACTTTCTGCAAAAGCAGTCAGCAAAAGCCACCTCAGGAACATCCTCAAAACTCATCAAGCTCCGAGAGGAACCCGCTGAATATGTGGACACTCAGAGAGGGAAGAGTCCAGTCAATAGCACACTTATCCCAGTCAAGGGCATCAACAACCTGGGCAACACCTGCTTCTTCAATGCTGTGATGCAGAATCTCTCTCAGACCCACATGCTGAATGACCTGATTCAAGATGTCAAGGAGAAAGGACATAAGATGAAGATCAGCCCCTCCACTGAGACTAACTTGGGGTCGCTGACTGTGACGTTGCCCAGCCCTGAACCCCTCACCTCAGCCATGTTCCTGTTCCTCCAAAGCATGAAGGAATCTGGAAAAGGGCCTGTATCTCCCAAGATCCTTTTCAACCAGCTCTGTCAGAAggcTCCTCGTTTTAAGGGTTACCAGCAGCAGGACAGTCAGGAATTGCTGCATTACCTCCTGGACTCTATGAGAGTGGAGGAGACAAAGCGCATTAAAGCGGGGATCCTTAAAGCCTTTAACAACCCCACAGAGAAGACTGCAGACGAGGAGACCAAACGACAAGTGAAGGCTTATGGAAAAGAAGGAGTGAAATTAAATTTTGTTGATCGAATCTTTGTCGGAGAGCTGACCAGCACCATAATGTGTGAAGAGTGTGAGCATATTTCTACAGTGAAGgaagcctttattgacatttcTCTTCCCATCATTGAGGAAAGGATTTCAAAGCCCACAAACCCTGCTAGACTGGGCAAAAGTGGGCGGGAACAAGACAGTCTGACCTCCCATGATGACTCATTAGCTGCCCACTCCCAGGCCAATCGAAACAGCAGGAGGCTCAGTGGACAGAAGCTACAGAGCCGCCATTCGTCCACGTCTCATGATGACCGAGGCCCAGACACTGTTTCTAGCCGTCAAGAGGAGGATCTCTGTGTGGCTGGCCGTGGCCTATCCAGTTACAGGACTGATACAATGGGCAGCCAGTCAGACTGCAGTGAAAAAGAGTCAAACCTGCAGGACAGCAGTAACGATGCAGACAGCGAGGCCTCTGAAAGTGAATGGTCTCCCCGAATCCCATCAGTGTCCAGTCACAGCAGCACATCAGATAAAACCTCAATCACCACAACTCTATCCACAACAACACACAATCCAAGTTTAAAATCGAACCCAAGCTCCACTCCATTACCCTCCATTAGGCCCCAGCAGGGCGGCGCTGTGGAGCAGCTTGTCAGCGCTGTGTCCAAACTGGGCCTGGTTCACACATCCACTGATACTCTACCCATCAGCCACAGCCAAGAGGAGCTGAGTGAGACCCGGGACAGAGACCGTCAACACCATCAAGGGGCCTTTCAAGTCCTCTGTCACAGCTACACCCCCAGCTCAAAAGAGTGCTCTGTCCAGTCCTGCCTTCATCAGTTTACCTCTATTGAGCTGCTTATGGGAAACAACAAGCTGCTCTGTGAAAACTGCACTGACAGGAGGCAGAGGCAGATGAAGAGGAGCGATAAGAAGGCAGAGAAGGTGTACACCAGTGCCCGTAAACAGATGCTCATATCTGCACTTCCTCCAGTCGTCACTCTTCACCTCAAACGCTTTCACCAGGCTGGGATGAATCTGAGGAAAGTTAATAGACATGTGGACTTTCCTCTTTTGCTGGACCTGGCACCTTTTTGCTCCGCCACTTGTAAGAACCTCGGGTCAGGAGAGCGTGTGCTTTACAGTTTGTATGGCATTGTGGAGCACAGTGGATCGATGCGAGGTGGGCATTATGCAGCCTATGTAAAGGTCCGAACACCTCAACGTAAACCTGAGCAGCGCCGGAACCAGTCAGGTTCCCGAGAGGCCTGTTCAGCTCCACAAGGTCAGTGGGTATATGTCAGCGACACCACTGTACAGACTGTCCCTGAGTCCAGAGTGCTGAACTCTCAAGCTTATTTACTTTTCTATGAAGAACTGCTATAGAGCTGGACGGACACATTAACCTAAGACGATCCAGATGAAGACAACAGGCAATATCAGCTCAGACAACAGCTAGCACTTACTGCATGCCGATTTCCCTGTATTTTAATGTAGGACTCCATATACTAAAAGATTGGTCTGAATGCAAATCGGGAGCCATTATTATTGATGTAAAATAATCTGCTGAATTTAAGTTAATAATGTTTTACAGCTAATATTtgagtttaaagtttttttttgtgcttatttTGCAGGAAAATTGCCAAAGATTAATTTAGGATGAACTATGTACAGAATATATCATAAGAGATGGACAATTGTCCAAAAGTGTCTATAATACCCTCTGTTGTGAAGGGGAAACTCAACACAATATGCAGCTGTTGCTTTCGGAGCTGTCATATTCTGAACTGGAACTCACACGTTATGATTTGCTTTAGGACCTTGTTACATTCACAGGCTTGAC

Function

symbol description
usp45 Predicted to enable thiol-dependent deubiquitinase. Involved in neural retina development and photoreceptor cell maintenance. Located in photoreceptor inner segment. Human ortholog(s) of this gene implicated in Leber congenital amaurosis. Orthologous to human USP45 (ubiquitin specific peptidase 45).

GO:

id name namespace
GO:0045494 photoreceptor cell maintenance biological_process
GO:0016579 protein deubiquitination biological_process
GO:0006508 proteolysis biological_process
GO:0006511 ubiquitin-dependent protein catabolic process biological_process
GO:0001917 photoreceptor inner segment cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004843 thiol-dependent ubiquitin-specific protease activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-100211-2 Predicted to enable thiol-dependent deubiquitinase. Involved in neural retina development and photoreceptor cell maintenance. Located in photoreceptor inner segment. Human ortholog(s) of this gene implicated in Leber congenital amaurosis. Orthologous to human USP45 (ubiquitin specific peptidase 45).

Ensembl:

ensembl_id ENSDARG00000075013

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00021223 True 3164 mRNA 0.48 18 32676517 32727199

Neighbor

gene id symbol gene type direction distance location
XLOC_010845 coq3 coding downstream 3489 32652350 ~ 32673028 (-)
XLOC_010844 faxcb coding downstream 26588 32630074 ~ 32649929 (-)
XLOC_010843 NA coding downstream 49077 32587438 ~ 32627440 (-)
XLOC_010841 fbxl4 coding downstream 93719 32566218 ~ 32582798 (-)
XLOC_010842 CR848729.1 coding downstream 102281 32574110 ~ 32574236 (-)
XLOC_010847 NA coding upstream 15143 32742342 ~ 32819765 (-)
XLOC_010848 MCHR2 coding upstream 93128 32820327 ~ 33001153 (-)
XLOC_010849 snap91a coding upstream 278489 33005688 ~ 33060053 (-)
XLOC_010850 dop1a coding upstream 335371 33062570 ~ 33097398 (-)
XLOC_010851 pnrc2 coding upstream 374652 33101851 ~ 33105677 (-)
XLOC_010626 CR392024.2 misc downstream 11781342 20895112 ~ 20895175 (-)
XLOC_010840 NA non-coding downstream 116734 32558055 ~ 32559783 (-)
XLOC_010839 NA non-coding downstream 287043 32387576 ~ 32389474 (-)
XLOC_010838 NA non-coding downstream 297841 32348773 ~ 32378676 (-)
XLOC_010852 BX537338.1 non-coding upstream 788567 33515766 ~ 33541958 (-)
XLOC_010853 NA non-coding upstream 833664 33560863 ~ 33592580 (-)
XLOC_010855 NA non-coding upstream 1008129 33735328 ~ 33736759 (-)
XLOC_010856 BX530064.1 non-coding upstream 1022868 33750067 ~ 33758285 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_09735579_09766657 USP45 coding CI01000027 null 9735489 ~ 9766657 (-)