XLOC_010956 (caspa)


Basic Information

Item Value
gene id XLOC_010956
gene name caspa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 41993551 ~ 42004544 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00021418
TTGTTGATTGGGCAATCTGTTAGAAAAAGGGAAAGAAACACATTGTGTTGACCTTCGGCATTCAGTCAGCGCCCTGAGCTAAACATGGCCAAATCTATCAAGGACCATCTTCAGGACGCTTTAAGTAATATTGGGGCGGATAATCTAAGAAGGTTTCAAAGCAGACTGGGCGATCGGAAGCAGGAACCGCGCGTCCGAAAATCTACAATCGAAAAGCTGAAAGACGAGATAGATCTGGTTGATTTATTGGTCAACACTTTCACATCTGACGCGGTTTCTGTAACAGTGGACATTTTAAGGGGTATCAAGTGTAATGCAGTAGCAGAGGAGCTCTTGGAGAACACAGGGCAAGGAGGAGTTTCCCAGCCGGAGCCACCTGTACCAGAACCAATTCCGAAGGATCCAGCTCAGTTGAAAGAACTGAAGGTTACTCCATGCAGCcagcaatttaaaaacaaaattcttaGAGAAAAAGGACAGGAGACTTATGAAATAAAAGACAAGTCAGTCAGAAAACGACTGGCCTTGCTTATCAACAACGTGGATTTTGACGATAAGGCTATGAAAAGGAGCGGCTCAGAGAAAGATGAAGAGAACATGGAAAAGCTGTTAAAGGAGCTGGATTATCAAGTTGTCAAGAGACCAAACCTTTCAGCAAAGGAAATGGATGAAGCCATCAGGGACTTTGCTCAACGTGAGGAACACAAGTATTCAGACAGCGCATTTGTGGTTATAATGTCCCACGGCAAAAGAGACGCCATTATGGGTGTCCATTACCATAGGACAAACAACCCTTCTGATTCCTTTCCGGTTGATAATGTCTACCGCCGTCTAAACTCAGAGAATTGTCCAGCTCTGCGCGATAAACCAAAGGTTATTCTCATCCAAGCCTGCAGGGGAGGTGAGCATGGCCGTGTTTGGGCCAGTGACGGTGAGCCTGATGAGCCAATAGAAATAGAGGACGATGACTTTGTGCACAAGGAGAAAGACTTCATTTCTCTGATGTCGTGCACCCCGGACACCAAATCTTACCGGCATGTGCAGAATGGAACGTTTTATGTCCAAACCTTAGTGGATGTGTTCATAAAATGCGCACATGAGGATCACATCGAGGAACTGTTCAGGAAGGTTCTAAGACGTTTCGAACACCCAAACATGATCGGAAACTTCAAGCAAATGGCATGTAAAGACAGAGCAACGCTGCCGAAGTTGTTCTACCTGTTCCCCGGACTCTGATAGCCAAGAAACAATTATAAGTTCACATCTGTGAATTTGAGACTCCTGTGTGCCTTTGCTTCTTCAATGATTCCTGAAAAGACTTTACAGTATGtctaaaaaaattgcttttaaaatgaaagataaaCTTATATATAAATGGACTTAAATTGTTTACTTGGATTCCCCTGAAGTAAAAACTTGTTCTGATACAAAACATTCCAGTTTAACATAGACATGGCTGTGTTTTTGACTTGGGTTATGTGAAAGCATGAAGAGTTCATAACACCAcaggcaaaaataaaaacacaccttCAAAAAACCCTA

Function

symbol description
caspa Enables Pyrin domain binding activity and cysteine-type endopeptidase activity. Acts upstream of or within embryonic viscerocranium morphogenesis; innate immune response; and positive regulation of apoptotic process. Predicted to be part of inflammasome complex. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; heart; hematopoietic system; integument; and male organism. Orthologous to human CASP1 (caspase 1) and CASP4 (caspase 4).

GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:0043065 positive regulation of apoptotic process biological_process
GO:0006508 proteolysis biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0061702 inflammasome complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004197 cysteine-type endopeptidase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0032090 Pyrin domain binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-000616-3 Enables Pyrin domain binding activity and cysteine-type endopeptidase activity. Acts upstream of or within embryonic viscerocranium morphogenesis; innate immune response; and positive regulation of apoptotic process. Predicted to be part of inflammasome complex. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; heart; hematopoietic system; integument; and male organism. Orthologous to human CASP1 (caspase 1) and CASP4 (caspase 4).

Ensembl:

ensembl_id ENSDARG00000008165

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00021418 True 1542 mRNA 0.43 7 41993551 42004544

Neighbor

gene id symbol gene type direction distance location
XLOC_010955 pycard coding downstream 3130 41984032 ~ 41990421 (-)
XLOC_010954 BX649388.1 coding downstream 28242 41955855 ~ 41965309 (-)
XLOC_010952 gramd1a coding downstream 32357 41902949 ~ 41961194 (-)
XLOC_010953 BX649388.3 coding downstream 44435 41948075 ~ 41949116 (-)
XLOC_010951 CR318611.1 coding downstream 110991 41882445 ~ 41882560 (-)
XLOC_010957 etv2 coding upstream 2546 42007090 ~ 42014272 (-)
XLOC_010958 zp3d.2 coding upstream 43818 42048362 ~ 42056137 (-)
XLOC_010959 zp3d.1 coding upstream 53374 42057918 ~ 42066617 (-)
XLOC_010960 dyrk1b coding upstream 67152 42071696 ~ 42152145 (-)
XLOC_010961 alkbh8 coding upstream 151520 42156064 ~ 42175617 (-)
XLOC_010626 CR392024.2 misc downstream 21098376 20895112 ~ 20895175 (-)
XLOC_010944 NA non-coding downstream 255553 41684868 ~ 41737998 (-)
XLOC_010942 BX005012.3 non-coding downstream 450688 41542079 ~ 41542863 (-)
XLOC_010970 CR854827.1 non-coding upstream 869196 42873740 ~ 42874709 (-)
XLOC_010975 NA non-coding upstream 968541 42973085 ~ 42974540 (-)
XLOC_010976 NA non-coding upstream 970003 42974547 ~ 42993892 (-)
XLOC_010981 NA non-coding upstream 1114569 43119113 ~ 43124227 (-)
XLOC_010987 NA non-coding upstream 1354381 43358925 ~ 43368871 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_03776983_03781753 NA coding CI01000027 null 3776138 ~ 3781891 (+)