XLOC_011204 (runx2a)


Basic Information

Item Value
gene id XLOC_011204
gene name runx2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 5351922 ~ 5516693 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00022378
CCGTATTTCCATCCGCTGATATCTGAACGGTCTCCTCAGACCGGAGcgcgtgtgtttgtttgttcccTTCCGATGCCTTGATATGATTTGTGCTCCCGCTTTAGGACTTCGAGGGTCACCACGACCTGCAGAAGAGGAGAGAGCCAACGTGTGGCTATGGCGTCTAACAGTCTTTTCAGCTCGGTGACTCCGTGTCAGCAGAACTTTTTCTGGGATCCGAGCACCAGCCGCAGGTTCAGTCCGCCGTCCAGCAGCCTTCAGCCGGTGGCGGGGAAGATGAGCGATGCGCAGCCGGAGCCGAACGCGGTGGTGCCGAGACTCCGACCTCACGACAACCGGACCATGGTGGAGATCATAGCGGACCACCCCGCCGAGCTCGTGCGCACGGACAGCCCCAACTTTCTGTGCTCGGTGCTGCCGTCTCACTGGAGGTGCAACAAAACGCTCCCTGTGGCGTTTAAGGTTGTGGCTCTGGGAGATGTTCCTGACGGGACGGTGGTGACGGTAATGGCTGGAAATGACGAAAACTATTCGGCTGAGCTGAGAAACGCCTCCGCTGTCATGAAGAATCAGGTGGCGCGTTTCAACGACCTGAGATTTGTTGGCAGAAGTGGAAGAGgAAAGAGCTTCACGCTGACAATCACAGTATTCACGAACCCACCGCAAGTGGCCACTTACCACCGAGCCATAAAGGTCACAGTGGACGGACCGCGCGAGCCGCGAAGACACAGACAGAAACTGGAAGACCCCCCTAAACCGCCGCTGTTCTCCGAGCGCCTGAGCGAATTAGAGCGTTTACGCCAGACCACCATGAGAGTCGCTGTGCAAACCCAGAGTCCCCGGCCGTCTCTCAACGCCACGCCGAACTCCTTCAATCCACAGGGGCAAACGCAGATCTCAGACCCTCGGCAGGTTCAATCCTCTCCGCCCTGGTCCTATGAGCAGCCCTATCCTCCATACCTGAGCCAAATGACGTCTCCCTCCATCCACTCCACCACCCCGCTGTCCTCCACCCGTGCCACCGGCCTGCCCACCATCAGCGACGTGCCACGACGCCTCTCAGGTACGTCAGAACTCAGTCCTTTCTCAGCCGACCCCCGCCAGTTTGAGCGTCAATTCCCAAGCCTGTCGTCCCTCACAGACAGCCGCTTTCCCAGTCCCAGAATGCACTATCCAGCAACATTCACCTACACCCCAACACCGGTGACCTCCGGCATGTCTCTGGGCATGTCCACCACCACCCACTACCACACATACCTGCCTCCACCGTACCCCGGATCCACCCAGAACCAAAGTGGGCCCTTCCAAACCAGCAGCACACCATATCTCTACTACGGCGCCTCATCCGGGTCATACCAATTCTCGATGGTGCCAGGGGGTGATCGGTCCCCATCCAGGATGCTTCCACCTTGCACTAGCGCATCCACCGGCAGCACCCTCATCAACCCCAACCTGCCCAATCAGACGGATGGAGGTGAGGCGGACGGCAGCCACAGCAGCTCTCCAACTGTGCTCAACTCCAGTGGCAGGATGGATGAGTCCGTGTGGCGGCCATATTGAGATGCTCTGGTTGAACAAAACCTCAATGCAGCACTGTTAGCCTTAAAGACAGAGTGTTAGAAATGAGGATGATCCGATTTGAAGCACAAA
>TCONS_00022379
ttttttttaaagtgtactgtaGCTTACCTTTGCTGACATTGTTGTGATGCGCATTCCGGTAGATCCGAGCACCAGCCGCAGGTTCAGTCCGCCGTCCAGCAGCCTTCAGCCGGTGGCGGGGAAGATGAGCGATGCGCAGCCGGAGCCGAACGCGGTGGTGCCGAGACTCCGACCTCACGACAACCGGACCATGGTGGAGATCATAGCGGACCACCCCGCCGAGCTCGTGCGCACGGACAGCCCCAACTTTCTGTGCTCGGTGCTGCCGTCTCACTGGAGGTGCAACAAAACGCTCCCTGTGGCGTTTAAGGTTGTGGCTCTGGGAGATGTTCCTGACGGGACGGTGGTGACGGTAATGGCTGGAAATGACGAAAACTATTCGGCTGAGCTGAGAAACGCCTCCGCTGTCATGAAGAATCAGGTGGCGCGTTTCAACGACCTGAGATTTGTTGGCAGAAGTGGAAGAGgAAAGAGCTTCACGCTGACAATCACAGTATTCACGAACCCACCGCAAGTGGCCACTTACCACCGAGCCATAAAGGTCACAGTGGACGGACCGCGCGAGCCGCGAAGACACAGACAGAAACTGGAAGACCCCCCTAAACCGCCGCTGTTCTCCGAGCGCCTGAGCGAATTAGAGCGTTTACGCCAGACCACCATGAGAGTCGCTGTGCAAACCCAGAGTCCCCGGCCGTCTCTCAACGCCACGCCGAACTCCTTCAATCCACAGGGGCAAACGCAGATCTCAGACCCTCGGCAGGTTCAATCCTCTCCGCCCTGGTCCTATGAGCAGCCCTATCCTCCATACCTGAGCCAAATGACGTCTCCCTCCATCCACTCCACCACCCCGCTGTCCTCCACCCGTGCCACCGGCCTGCCCACCATCAGCGACGTGCCACGACGCCTCTCAGGTACGTCAGAACTCAGTCCTTTCTCAGCCGACCCCCGCCAGTTTGAGCGTCAATTCCCAAGCCTGTCGTCCCTCACAGACAGCCGCTTTCCCAGTCCCAGAATGCACTATCCAGCAACATTCACCTACACCCCAACACCGGTGACCTCCGGCATGTCTCTGGGCATGTCCACCACCACCCACTACCACACATACCTGCCTCCACCGTACCCCGGATCCACCCAGAACCAAAGTGGGCCCTTCCAAACCAGCAGCACACCATATCTCTACTACGGCGCCTCATCCGGGTCATACCAATTCTCGATGGTGCCAGGGGGTGATCGGTCCCCATCCAGGATGCTTCCACCTTGCACTAGCGCATCCACCGGCAGCACCCTCATCAACCCCAACCTGCCCAATCAGACGGATGGAGGTGAGGCGGACGGCAGCCACAGCAGCTCTCCAACTGTGCTCAACTCCAGTGGCAGGATGGATGAGTCCGTGTGGCGGCCATATTGAGATGCTCTGGTTGAACAAAACCTCAATGCAGCACTGTTAGCCTTAAAGACAGAGTGTTAGAAATGAGGATGATCCGATTTGAAGCACAAA
>TCONS_00022380
aaagtgtactgtaGCTTACCTTTGCTGACATTGTTGTGATGCGCATTCCGGTAGATCCGAGCACCAGCCGCAGGTTCAGTCCGCCGTCCAGCAGCCTTCAGCCGGTGGCGGGGAAGATGAGCGATGCGCAGCCGGAGCCGAACGCGGTGGTGCCGAGACTCCGACCTCACGACAACCGGACCATGGTGGAGATCATAGCGGACCACCCCGCCGAGCTCGTGCGCACGGACAGCCCCAACTTTCTGTGCTCGGTGCTGCCGTCTCACTGGAGGTGCAACAAAACGCTCCCTGTGGCGTTTAAGGTTGTGGCTCTGGGAGATGTTCCTGACGGGACGGTGGTGACGGTAATGGCTGGAAATGACGAAAACTATTCGGCTGAGCTGAGAAACGCCTCCGCTGTCATGAAGAATCAGGTGGCGCGTTTCAACGACCTGAGATTTGTTGGCAGAAGTGGAAGAGgAAAGAGCTTCACGCTGACAATCACAGTATTCACGAACCCACCGCAAGTGGCCACTTACCACCGAGCCATAAAGGTCACAGTGGACGGACCGCGCGAGCCGCGAAACCCTCGGCAGGTTCAATCCTCTCCGCCCTGGTCCTATGAGCAGCCCTATCCTCCATACGTGAGGCGGACGGCAGCCACAGCAGCTCTCCAACTGTGCTCAACTCCAGTGGCAGGATGGATGAGTCCGTGTGGCGGCCATATTGAGATGCTCTGGTTGAACAAAACCTCAATGCAGCACTGTTAGCCTTAAAGACAGAGTGTTAGAAATGAGGATGATCCGA

Function

symbol description
runx2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including chondrocyte differentiation; ossification; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including cranium; fin; osteoblast; osteoprogenitor cell; and scale. Human ortholog(s) of this gene implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Orthologous to human RUNX2 (RUNX family transcription factor 2).

GO:

id name namespace
GO:0030097 hemopoiesis biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0030182 neuron differentiation biological_process
GO:0001503 ossification biological_process
GO:0002062 chondrocyte differentiation biological_process
GO:0045595 regulation of cell differentiation biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040629-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including chondrocyte differentiation; ossification; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including cranium; fin; osteoblast; osteoprogenitor cell; and scale. Human ortholog(s) of this gene implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Orthologous to human RUNX2 (RUNX family transcription factor 2).

Ensembl:

ensembl_id ENSDARG00000040261

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00022378 False 1650 mRNA 0.58 7 5351922 5516693
TCONS_00022379 False 1498 mRNA 0.58 6 5426087 5516693
TCONS_00022380 True 786 mRNA 0.57 5 5426095 5516680

Neighbor

gene id symbol gene type direction distance location
XLOC_011203 cdc5l coding upstream 246000 5061135 ~ 5105922 (+)
XLOC_011202 FO082819.1 coding upstream 481400 4870403 ~ 4870522 (+)
XLOC_011200 KLHL29 coding upstream 497071 4578552 ~ 4854851 (+)
XLOC_011201 CABZ01016068.1 coding upstream 690879 4660919 ~ 4661043 (+)
XLOC_011199 NA coding upstream 859209 4489255 ~ 4492713 (+)
XLOC_011205 fam167aa coding downstream 94473 5611166 ~ 5622440 (+)
XLOC_011206 CU571310.1 coding downstream 106821 5623514 ~ 5629978 (+)
XLOC_011207 rp1l1a coding downstream 251915 5768608 ~ 5822120 (+)
XLOC_011208 CU929322.1 coding downstream 320615 5837308 ~ 5837694 (+)
XLOC_011209 fndc4b coding downstream 329509 5846202 ~ 5928942 (+)
XLOC_011198 NA non-coding upstream 873190 4470293 ~ 4478732 (+)
XLOC_011197 NA non-coding upstream 886364 4460750 ~ 4465558 (+)
XLOC_011213 NA non-coding downstream 691466 6208159 ~ 6211272 (+)
XLOC_011217 NA non-coding downstream 869947 6386640 ~ 6392567 (+)
XLOC_011220 NA non-coding downstream 1011330 6528023 ~ 6528543 (+)
XLOC_011230 NA non-coding downstream 1710037 7226730 ~ 7229012 (+)

Expression


Co-expression Network