CI01000113_01834891_01839297 (KCNJ2, KCNJ2A)


Basic Information

Item Value
gene id CI01000113_01834891_01839297
gene name KCNJ2, KCNJ2A
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000113
NCBI id null
chromosome length 2886875
location 1834891 ~ 1840126 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000113_01834891_01839297.mRNA
ATGAAGGCAGCCTGTGGTTACGGAAATCCTGATTGTTGTTTGTGTGTTGGTCCATGTGAGAGGTCGAAAGTGTTTCTCCAACGCGTCCTCCAAAAACTCAGACTGTTGTCCAAAGCAGACGAGGCTCAGCCCCCTCATTCGGAACTGATGGGAAGTGTGAGAGCCCACCGATACAGCATAGTTTCCTCGGAGGAAGGCGGGATGAAGCTGTCCCCCATCGCTGTGCAAAACGGATACGGCAATGGAAACGTGGGCAGCAAAGTGCACACGCAGCACCAAGAACAAAGCCGCTTCGTCAACAAGGACGGACACTGTAATGTGCAGTTCATCAACATGAGTGAAAAAGGTCAACGCTACCTGGCGGACATCTTCACGACATGCGTTGACATCCGCTGGCGTTGGATGATGGTCCTCTTCTGCCTCTCTTTCCTGCTGTCCTGGCTTCTCTTTGGATTAATATTCTGGCTTGTTGCACTTTCGTCAGGGGACTCGGAGAATCAAGAGCAGATTTGCATTTCCAATGTCGACAGCTTCACTGCAGCCTTCCTGTTTTCCGTGGAGACACAAACAACTATCGGATATGGCTACCGATATGTAACGGAGGACTGTCCTATTGCAGTCTTCATGGTGGTTTTCCAGAGCATCTTGGGATGCATCATTGATGCCTTCATTATTGGTGCGGTCATGGCTAAGATGGCCAAGCCTAAGAAAAGAAACGAAACCCTTGTGTTCAGTCACTATGCCACAATAGCCATGAGGGACGGTAAACTGTGTCTGATGTGGAGGGTCGGGAACCTCCGGAAAAGCCACCTGGTGGAAGCTCACGTTCGCGCCCAGCTGCTCAAATCTCGCACCACCGCTGAAGGCGAGTTCATCCCGCTGGATCAGATAGACATTGATGTCGGATTTGACACTGGTATTGACCGTATATTTTTAGTGTCCCCCATCACCATCGTCCATGAGATTGATGAGGACAGTCCATTCTATGACATGAGCAAACAGGAACTGGAAAGTTCGGAGCTGGAGATAGTCGTGATTTTGGAAGGCATGAATCGGTATAATGAAGCTTGTAGTGAAGATGAGAACCGAATGTTTCCTTTTGATCTCGTCTATGCCATTAAACCTACAATAGAGGAGTTTCTGAGCATTTAAACTCACTGCAATGATAACACAATTCAAGATAAATGAGCTGAAGTATAAAGTTAGAACACTAGCATCCATATTTCACGGTTATAATGTAGTTGTCATTGACAGTAGGCATGTTTATGTGAAGAGCTATGTGTTCACAGATGATTTGAAAACCTTGACTGAAAATAACGAAAGGAACCTGTTAATGAGCTGGTCTCTTAACATACTTCTCTACTCTTTCTATACAGTTCTGTAGCAGAAATCTGTTGATGACGTACATTTGATGTGGTTAAATACGTTACGATATCAGTACTGAAGATTAGCCATCCATTTTAATGACAGTATAAGCTAATCTAGGGCACTTATTGTATGACCATTAGTGAACGTAAAGCTCCTCAGTCCATGTACTGCATCTTCTGTGACCTGAGCGACAGGGCTTGTTAAAGCACACTTAACATCTCAGGGTTTGGATGAAATCTGGCATTCATACAGCACAAATGGTCAAAGAGTTGTATATACACTACAGCAAATCTTTGAATAATATGTAAAGAATGTCATGTTCATAGCAGTATATGTGCTTTCGATGTGCAATATAGCTTCAGTGACTGAAGACATGAATGTTAATGTTTATGAATGAAGGCACGAATGTTACTTATCTGCTGCTATTTAGGAAAGATTATAAAATATAAATATGTTAACAAAAGGAGAAAGAAACTATTTTGTTTTGTATGACATAATGTGTTAAAACCCAAGTAATAATGACTTGCAATGCTGTGAAACAGTTGGGGACCAATATCTAATCTGTTTTTTTTATATATATATACAAGACTGTGAGAGTAGCTATCAAACCACA

Function

symbol description
kcnj2a Enables inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of ion transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in atrium and cardiac ventricle. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2).
kcnj2 Enables identical protein binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and voltage-gated potassium channel activity. Involved in several processes, including cardiac muscle cell action potential; potassium ion import across plasma membrane; and protein homotetramerization. Is intrinsic component of membrane. Part of voltage-gated potassium channel complex. Implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Biomarker of atrial fibrillation.

NR:

description
inwardly-rectifying channel, subfamily J, member 2

GO:

id name namespace
GO:0006810 transport biological_process

KEGG:

id description
K04996 KCNJ2, KIR2.1; potassium inwardly-rectifying channel subfamily J member 2

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000113_01834891_01839297.mRNA True 1981 mRNA 0.43 3 1834891 1840126

Neighbor

gene id symbol gene type direction distance location
CI01000113_01826332_01833431 NA coding upstream 1362 1825854 ~ 1833529 (+)
CI01000113_01761054_01815819 NA coding upstream 18894 1760927 ~ 1815997 (+)
CI01000113_01716646_01752755 NA coding upstream 81540 1715749 ~ 1753351 (+)
CI01000113_01698764_01709585 NA coding upstream 125183 1698624 ~ 1709708 (+)
CI01000113_01691097_01696776 NA coding upstream 138115 1691062 ~ 1696776 (+)
CI01000113_01983091_01989335 NA coding downstream 142965 1983091 ~ 1989335 (+)
CI01000113_01994682_02001599 DNAAF5 coding downstream 154556 1994682 ~ 2002028 (+)
CI01000113_02042831_02055567 NA coding downstream 199872 2039998 ~ 2056124 (+)
CI01000113_02059842_02092732 SLC9A3R2 coding downstream 219716 2059842 ~ 2093663 (+)
CI01000113_02111396_02122911 NA coding downstream 270509 2110635 ~ 2123037 (+)
G331790 NA non-coding upstream 53201 1733674 ~ 1781690 (+)
G331793 NA non-coding upstream 77913 1755457 ~ 1756978 (+)
G331756 NA non-coding upstream 196458 1638118 ~ 1638433 (+)
G331755 NA non-coding upstream 198231 1636151 ~ 1636660 (+)
G331840 NA non-coding downstream 15705 1855831 ~ 1856934 (+)
G331820 NA non-coding downstream 66293 1906419 ~ 1909070 (+)
G331824 NA non-coding downstream 158318 1998444 ~ 2057885 (+)
G331833 NA non-coding downstream 190712 2030838 ~ 2034228 (+)
G331907 NA non-coding downstream 231409 2071535 ~ 2072337 (+)
G331759 NA other upstream 5988 1668002 ~ 1828903 (+)
G331767 NA other upstream 171636 1662785 ~ 1663255 (+)
CI01000113_01424978_01425704 NA other upstream 409185 1424968 ~ 1425835 (+)
G331615 NA other upstream 588318 1246291 ~ 1246573 (+)
G331487 NA other upstream 912758 917735 ~ 922133 (+)
CI01000113_02342987_02345449 SYCE2 other downstream 503295 2342987 ~ 2346006 (+)
CI01000113_02548934_02576888 TBL3 other downstream 728641 2548934 ~ 2577790 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_025124 kcnj2b coding NC_007114.7 CM002887.2 12861158 ~ 12862480 (+)