XLOC_011362 (kif11)



Basic Information


Item Value
gene id XLOC_011362
gene name kif11
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 19481049 ~ 19497006 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00022637
GTCCGCTAACTGCAGTGCTAGAAGACTCATCGTCAGAGCTTACGGCACGTAGAGCGTATTCAAATAAACCGTGTTACTGGAGGGATTTTAAACTATTTTGCCATTTCTTGTGGTCTACTCTTAAGCAAGATCGGCTTAACGGTTACATTTAAAGGGCATTTGAGATCTGGAGCCTAGAAGACGCTCCTTCAACATGGCATCATCACAAGTACCAGCAGCCAAAAAAGATGAGAAGGGCAGAAACATACAAGTGGTTGTACGATGCAGACCCTTTAACACAGTGGAGCGTAAATCTGGCTCTCACACTGTTGTTGAATGTGACCAGAACCGAAAAGAGGTGATTATGCGTACTGGAGGTGCCACAGACAAGGCAGCAAGAAAAACATACACTTTTGATATGgTTTTTGGCCCTTCTGCCAAACAAATTGAAGTTTATAGGAGTGTGGTTTGCCCCATATTAGATGAAGTTATCATGGGCTATAACTGCACAATCTTTGCATATGGGCAAACCGGAACAGGCAAAACCTTCACAATGGAAGGTGACCGATCACCCAATGAGGAGTTTACTTGGGAAGAGGACCCTCTGGCTGGAATAATTCCCAGGACTCTACATCAGATCTTTGAAAAACTGTCTAATAATGGCACAGAGTTCTCAGTGAAGGTGTCTCTGCTGGAAATTTATAACGAGGAACTGTTTGACCTGCTCAGCCCTGCTCCTGATGTCACAGAGAGATTACAGCTCTTTGATGATCCCAGAAATAAAAGGGGTGTGACCATTAAAGGTCTGGAGGAAATCACCGTACACAATAAGAATGAGGTGTATCAGATCCTGGAGAGAGGAGCAGCCAAGAGGAAGACTGCCTCCACACTCATGAATGCCTATTCCAGTCGATCCCACTCTGTGTTCTCTGTCACTATTCACATGAAGGAAATCACACTGGATGGGGAAGAGCTAGTTAAGATTGGTAAACTCAACTTGGTGGATCTTGCAGGTAGTGAGAACATCGGACGATCTGGTGCTGTGGATAAGCGTGCACGTGAAGCTGGCAACATCAACCAGTCTCTGCTAACTCTGGGTCGTGTAATCAAGGCTTTGGTGGAGAGAGGGCCTCACGTGCCCTACAGAGAGTCTAAACTAACCCGCATACTGCAGGACTCGCTAGGAGGACGCACCAAAACCTCTATCATCGCCACTGTGTCTCCTGCCTCCATCAATCTGGAGGAAACTCTGAGCACTTTAGACTATGCTAACAGAGCTAAGAGCATCATGAATAAGCCTGAGGTCAATCAAAAGCTTACCAAGAGAACCCTCATCAAGGAATACACAGAGGAAATTGAGAGACTGAAGAGAGATTTGGCTGCCACCCGTGACAAACATGGAGTGTACCTTTCCGTTGATAACTATGAGACTTTGAATGGTAAAATTGTGTCTCAGGAAGAGCAGATTACAGAGTACACTGAGCGGATAGCTGCTATGGAGGAGGAGCTCAAAAAGATTATAGACCTGTTCACAGATAGTAAGCAGAAATTGGAACAGTGCACCGAGGACCTGCAAGACAAAAACCAGAGACTGGAGGAGGCTCACAAAGACCTATCGGAGACCAGGCACCGCCTCAATCAGGAGGAATTCATCAGTACACAGCTTCAAACCAATGAGAGTCACCTCTATAACACTGCTGACCAGTTGTTGAGCACTGCTGAGGCCAGCACACAGGATGTCGGTGGTCTCCATGCTAAGCTACAAAGGAAGAAGGATGTGGAGCTTCATAACAGTAAGGTTCAGGAGAGCTTCTCCCAGTGCATGGAGAACTGCTACAACAGCATGCAGACCTCACTGAAGGAGCAGAGCCAAAAACATGCTGCCATGATTGATTATTACCGCTCTTCTGTGGGTGAGCTGCTGAACACCAATGGCAAGGTGTTTAAGGAGACTTTGAGTGCTGTGTGCGAGTCTTACAGCAGTATTAAAGGAGCTGTGGGAGAAGGTGTAGAGCGGTGTAAGGAGCAAGTGTTAAATCAGGAGAAACTCTCTCAGGATGCTCAAAACAGCATCCTGGAAATTCTGGATGAACACAAACAGCATCTTGAGGAGGTTCTGGTTGCCCAGGCGGTGCCAGGTATCAGGTCTGTCATGTCCATGAATGACAATTTGAAGCAAACCCTTCACAAATACCACAATCTGGCTGAGCAGATGCAGGGTGTGAAAGCAGATATGATGACGTTTTTTGATGCGTACACTGAATCACTGGCCAGTATGCGAGAGTGCGCTTTGCAGGGTTTTAACACACTGCGTGCCGAACATGACAAACTCAAACAACAAATCAGCCAAGCTGGAAACAGCCATCAAGTGCGTGTGGCCGAGCTGGTTCAGTGTTTGCAGAACCAAATGAATCTGCTGGCGGTGGACACTCAGAATGACTTTGAGGGTCTTTCACAAGCAGCATCTGCCCAGATTCCTCCACTGGAAACATTACAGAGCTCCATAGAGAGTAAATGCACAGTGGCTGAGGAGCAGGCTGTGTCTGTTCGTGCTCGACTGGGTTCCTCTGTTCATGGAGTGATTTCAGAGATGAATAGTGTGACTAAGGAGGGAGAGAGGGCGCTGGAGGAGTGTGCTGGTTATTGTGGACACCTGCAGACATCGCTGGACTCGCTGGCTGAGTCAGGACTCAAGTGGTGCGATGAAGCTAAAGGCTTGACTGAGAGTAAAGCCCAGGAGCAACTCAAActcatcagacagacagacactgcTGTGCAAGACCTGCTGAAGtcTGTGGAGGAAAAGGGTGAGAAAGCTGTTCAGGACTGTGAAGCCAGATTGGGTCAAATGCAGCAGGAAATGGAAGCAACCCTGGGTCGTGTGGAAATGCAGACCAGCAAAGATGAAGCGACATTGCAGGAGCACAGAGAGACCCTGTCCTCCATCAACACTCAGGCACTGGACACCGTACACAACTTTATCAGCTCAGAGCTACGGCAGGATTTACCAACAGGAACGACCCCTCAGCGCAAAGAGTACATGTACCCACGTGTGCTGAGCAGGCCGAGGAGTAGAGAGGAGCTGGAAGAGGAGTTCAGAGCTCAGCAAGAGCAGCTTCAGTCTGAACTGAAGCCGTGTGAGATCGTaatggaggtggaggaggagaaaCCTGTCGACCAGGACTCTCTGGAGGATGACGTCAGTGTTTCTAGTGATGGAAACAACACTGAACAGTCGTGCTCTGATGAGAACCTGATATGTTATGAGAATGGAAGGATTCCTTTTTTCAAGAAGAAAAGCAAGAAGGAAAATGGCAGTAAATCACTGAACCGTTCAAAGGTGGAGAATGACAGCATGTCAACACCACCCCGCTCTAAACTTCCACTCAGATGTCAGAATTAACCTAAATTATGTTGCCAATATTACTCCCTTCGTGTATTAATCTTCCAAGTCCTTTTGTGTCTTAAACGTTGCATTTTTTTAACTATGTCTTTTTTAAACATCGATTATCAATGTATTTGTCTTATGTCTGTCCACACAAGTCAGTTATAACTTCAGGGTGATTTCGTACTGTTACTTTTCCTGTTTCACTAGCGTTTAGGCTTGTTTGTATTTGTTCAAGGTTTTGTATGTTTAATTGAAGACTAAAAGAAAATGGTCCACTCCATctctcaaataataaaatatttttaaagta
>TCONS_00022638
gtgtgcatgcagtcTGTGGAGGAAAAGGGTGAGAAAGCTGTTCAGGACTGTGAAGCCAGATTGGGTCAAATGCAGCAGGAAATGGAAGCAACCCTGGGTCGTGTGGAAATGCAGACCAGCAAAGATGAAGCGACATTGCAGGAGCACAGAGAGACCCTGTCCTCCATCAACACTCAGGCACTGGACACCGTACACAACTTTATCAGCTCAGAGCTACGGCAGGATTTACCAACAGGAACGACCCCTCAGCGCAAAGAGTACATGTACCCACGTGTGCTGAGCAGGCCGAGGAGTAGAGAGGAGCTGGAAGAGGAGTTCAGAGCTCAGCAAGAGCAGCTTCAGTCTGAACTGAAGCCGTGTGAGATCGTaatggaggtggaggaggagaaaCCTGTCGACCAGGACTCTCTGGAGGATGACGTCAGTGTTTCTAGTGATGGAAACAACACTGAACAGTCGTGCTCTGATGAGAACCTGATATGTTATGAGAATGGAAGGATTCCTTTTTTCAAGAAGAAAAGCAAGAAGGAAAATGGCAGTAAATCACTGAACCGTTCAAAGGTGGAGAATGACAGCATGTCAACACCACCCCGCTCTAAACTTCCACTCAGATGTCAGAATTAACCTAAATTATGTTGCCAATATTACTCCCTTCGTGTATTAATCTTCCAAGTCCTTTTGTGTCTTAAACGTTGCATTTTTTTAACTATGTCTTTTTTAAACATCGATTATCAATGTATTTGTCTTATGTCTGTCCACACAAGTCAGTTATAACTTCAGGGTGATTTCGTACTGTTAC

Function


symbol description
kif11 Predicted to enable plus-end-directed microtubule motor activity. Acts upstream of or within angiogenesis; neurogenesis; and regulation of cell cycle. Predicted to be located in microtubule. Predicted to be active in nucleus and spindle microtubule. Is expressed in blood island; central nervous system; proliferative region; radial glial cell; and trunk. Human ortholog(s) of this gene implicated in microcephaly with or without chorioretinopathy, lymphedema, or mental retardation. Orthologous to human KIF11 (kinesin family member 11).

GO:

id name namespace
GO:0051726 regulation of cell cycle biological_process
GO:0090307 mitotic spindle assembly biological_process
GO:0001525 angiogenesis biological_process
GO:0007018 microtubule-based movement biological_process
GO:0022008 neurogenesis biological_process
GO:0005874 microtubule cellular_component
GO:0005876 spindle microtubule cellular_component
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed molecular_function
GO:0003777 microtubule motor activity molecular_function
GO:0008017 microtubule binding molecular_function

KEGG:

id description
ko03036 Chromosome and associated proteins
ko04812 Cytoskeleton proteins

ZFIN:

id description
ZDB-GENE-020426-1 Predicted to enable plus-end-directed microtubule motor activity. Acts upstream of or within angiogenesis; neurogenesis; and regulation of cell cycle. Predicted to be located in microtubule. Predicted to be active in nucleus and spindle microtubule. Is expressed in blood island; central nervous system; proliferative region; radial glial cell; and trunk. Human ortholog(s) of this gene implicated in microcephaly with or without chorioretinopathy, lymphedema, or mental retardation. Orthologous to human KIF11 (kinesin family member 11).

Ensembl:

ensembl_id ENSDARG00000010948

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00022637 False 3677 mRNA 0.46 23 19481049 19497006
TCONS_00022638 True 799 lncRNA 0.46 4 19495406 19496886

Neighbor


gene id symbol gene type direction distance location
XLOC_011361 NA coding upstream 173643 19307062 ~ 19307406 (+)
XLOC_011360 NA coding upstream 180877 19208475 ~ 19300172 (+)
XLOC_011358 NA coding upstream 211670 18898695 ~ 19269379 (+)
XLOC_011359 NA coding upstream 461016 19017530 ~ 19020033 (+)
XLOC_011357 si:dkey-288a3.2 coding upstream 608899 18810904 ~ 18872150 (+)
XLOC_011363 slc22a15 coding downstream 2151 19499157 ~ 19511206 (+)
XLOC_011364 CU571091.1 coding downstream 16565 19513571 ~ 19531819 (+)
XLOC_011365 NA coding downstream 109914 19606920 ~ 19614265 (+)
XLOC_011366 rgs7a coding downstream 129473 19626479 ~ 19749179 (+)
XLOC_011367 NA coding downstream 676812 20173818 ~ 20189395 (+)
XLOC_011355 NA non-coding upstream 680503 18798007 ~ 18800546 (+)
XLOC_011370 NA non-coding downstream 754455 20251461 ~ 20437298 (+)
XLOC_011376 NA non-coding downstream 1220970 20717976 ~ 20725895 (+)

Expression



Co-expression Network