XLOC_011681 (pgfb)


Basic Information

Item Value
gene id XLOC_011681
gene name pgfb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 44697604 ~ 44752439 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00023182
GGAGATTTAAATGATGAACTTGTTGAAAGGTAGTCAGGGCGCTCATGTGGAAGTGTGCCACTCTATTTGGGAAAGCAGGAAGCACGCAAACTGACGCTGGAGCTCCAGAAGCGCGCAAGGACCTTTAAAACCTGCAAACTGTAACTGCAAACACTGGACATTGCATAAGGacttatttaaaacactttaccACGTGCATTTACTACAGGGAGCGGTAGATTGGGTGCAATTACGTGACGTGTCACAGCTgttgaaaatattaaatttaaattgtttaatttaatttgagaAAACCTCCGACAAGGAAGACGCAATTTGGACATTTAGAATCGTTTTGTGGAATAACTGCTGAAATTGGATGGACTATTCGGGCGGACTACTGTTTGGATTTTCCTTCAATTAAACTTGTCTTGGCGTTCGAGATGAGTTATTTGACGTCACTGTTACGAGTATTTGCCGCGGTGCAGTTGAGCCTTTTACCTGGACAGAGTTCTTCGTTGGTCAATGTAAACAGCACTGATAAAGTGATGCTGTTTCAGGAGGTTTGGGGGAAGAGCTTCTGCCGCACTATAGAGAAGCTGGTGGAGGTGGTTCAGGAGTACCCAGGGGAGGTGGAGCACATTTTCAGCCCCGCCTGCGTGCCATTGGTCCGTTGCGCTGGTTGCTGTGGCGATGAGAATCTGGAGTGTCACCCTACGCTCACTTCCAACACCACCATGCAATTATTAAAGATTAAGCCAGCAGAGCAGGGCCAGGAATATGTGGAGATGACCTTTGTGGAGCACAAAGCCTGTGAATGTAGACTAAGAAAACCTACAACAAAACAAGACAGATGGAAACCCAGAAATAGAGGGAGAAAAAGGAAGGAGAAGCAGAAAGCCAAAGACTGTGACCGGTGTCAGCCTCCCCGCAGGTAAACGCTGTCTCGCCATGATGCCAGTCAATCACGCGCATCCGCCCCTCTCTGTGCGACCCTCACCATGGTCATCATTCACTCCTGGATCCCGCCACCTCTCCACACTCCTCGATCCAGGCGCAGAGCTGTAATGGTAGAGGGGCTTCTGTCAGCACACGGGGGAGCTTCCAGTCATCCATACCGAAAAACTGCTGCACAGCTcttactgaagaaaaaaacaaaacaaaaaacaacagcagGAGACCAAACTTAAAATCTTAGACTGACGTCAACCCTTTGGacattatcataataatataataagataattattttattgtttaatagtaatattattattagtagaagtAGCATAGTTACAATAGCGACCAGTCTTCCCTCTTATTTATTAAAATCCGCTGAAGTAAAACAGCTGCATTCCATGATTAGGGATCAACAAAGGCATTGTGTATTTGGAAAGAAGTCTAGAAGGAATCACACAATGAAAATGCCAAAGATGTTTTCATCTCTTTACTGCTATGCAAACTATATTACCCTTTAATTAAGCGAAAACCTCGTCAGACGCTCATACGTGATGCTGTGGTTAAAACTCCAGACTAGAGCTTCTGTGTGAGTTTAGcactatggcaagcctttttagcattcattttcctttggcttaatgccttatttatcagcaatcaccacagcgg

Function

symbol description
pgfb Predicted to enable chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor binding activity. Predicted to be involved in several processes, including positive regulation of chemotaxis; positive regulation of endothelial cell proliferation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor).

GO:

id name namespace
GO:0045766 positive regulation of angiogenesis biological_process
GO:0038084 vascular endothelial growth factor signaling pathway biological_process
GO:0002040 sprouting angiogenesis biological_process
GO:0050930 induction of positive chemotaxis biological_process
GO:0001525 angiogenesis biological_process
GO:0048010 vascular endothelial growth factor receptor signaling pathway biological_process
GO:0060754 positive regulation of mast cell chemotaxis biological_process
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0001666 response to hypoxia biological_process
GO:0001938 positive regulation of endothelial cell proliferation biological_process
GO:0005615 extracellular space cellular_component
GO:0016020 membrane cellular_component
GO:0005172 vascular endothelial growth factor receptor binding molecular_function
GO:0008083 growth factor activity molecular_function
GO:0042056 chemoattractant activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-131127-445 Predicted to enable chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor binding activity. Predicted to be involved in several processes, including positive regulation of chemotaxis; positive regulation of endothelial cell proliferation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor).

Ensembl:

ensembl_id ENSDARG00000076767

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00023182 True 1608 mRNA 0.44 7 44697604 44752439

Neighbor

gene id symbol gene type direction distance location
XLOC_011680 naa30 coding upstream 220892 44463230 ~ 44476712 (+)
XLOC_011679 ap5m1 coding upstream 243582 44441042 ~ 44454022 (+)
XLOC_011678 NA coding upstream 304817 44382333 ~ 44392787 (+)
XLOC_011677 BX548045.2 coding upstream 406084 44291405 ~ 44291520 (+)
XLOC_011676 NA coding upstream 434785 44258051 ~ 44262819 (+)
XLOC_011682 cipca coding downstream 3808 44756247 ~ 44761580 (+)
XLOC_011683 NA coding downstream 9185 44761624 ~ 44763410 (+)
XLOC_011684 tmem63c coding downstream 27727 44780166 ~ 44923661 (+)
XLOC_011685 coq6 coding downstream 257429 45009868 ~ 45030025 (+)
XLOC_011686 gstz1 coding downstream 353985 45106424 ~ 45114519 (+)
XLOC_011675 NA non-coding upstream 441677 44249450 ~ 44255927 (+)
XLOC_011672 NA non-coding upstream 689766 44004121 ~ 44007838 (+)
XLOC_011687 CU695222.2 non-coding downstream 425187 45177626 ~ 45180746 (+)
XLOC_011688 NA non-coding downstream 440741 45193180 ~ 45200541 (+)
XLOC_011691 NA non-coding downstream 595584 45348023 ~ 45349995 (+)
XLOC_011702 dre-mir-203a non-coding downstream 1055714 45808153 ~ 45808248 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000315_00820696_00824054 PGFB coding CI01000315 null 820696 ~ 824557 (+)