XLOC_011690 (capn3a)


Basic Information

Item Value
gene id XLOC_011690
gene name capn3a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 45305645 ~ 45346635 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00023198
TCaatcccttaaaaaaaaaacagtgagacAAGATGCCCTATACGCCGTCTGGGTTCTTCTGCGACCGTTTAATTCGGGAGAGGGAGAGAAGGGATGGCGAAGGGTCGCTGAGCAAACCCATTCGCTTCAGTGGCCAGGACTACACCCTCCTCAAGCAGGAGTATCTCCAGAAGAAGACCCTGTTCGAGGACGAGACCTTCCCTGCTACTGTGGACTCTCTGGGCTATAAAGAACTGGGCCACAAGTCTAACAAAGTCAAGAACATCGTCTGGAAACGTCCCAAGGAGATCTGCGATAACCCACAGTTCATTGTCGGAGGCGCTAGCAGGACTGATATCTGCCAGGGAGATCTGGGTGACTGCTGGTTGCTTGCAGCCATTGCCTGTCTGACTCTGAATGACAAGCTGCTGTATCGTGTTATTCCTCAAGAGCAGAGCTTCTCCGAACAATATGCAGGAATTTTCCATTTCCAGTTCTGGCGATATGGGGATTGGGTGGATGTTGTGGTTGATGACCGCATTCCCACCTTCAACAACCAACTGGTGTTCACCAAGTCTGCTGAGAGGAACGAGTTCTGGAGCGCTCTTCTGGAGAAGGCTTACGCTAAGCTTCATGGGTCCTATGAGGCCCTGAAGGGTGGAAACACAGCCGAGGGAATGGAGGACTTCACTGGTGGAGTGACTGAATTCTACGAGATGAAGGAGGCGCCCAAAGAGCTGTATAAGATCATGCAGAAAGCTCTAGAGAGAGGCTCACTCATGGGCTGCTCCATTGATTCTCTGGTTCCAGCCCGCTTTGAAACTCGTACTGCGACAGGTCTTGTGAAGGGTCATGCCTACTCTGTGACCGCTGTTGAGGAGtgtaaacAGAGCCAGCAGAAGGAGTCTAGAGTGCGTCTGGTGCGTTTGCGTAACCCCTGGGGTCAAGTAGAGTGGAATGGACCATGGAGTGACAATTCTAAAGAATGGGAAAGTCTTTCTAAAGCGGAAAAAGAGAAACTCCAGCAACAGAACGCTGAAGATGGAGAGTTTTGGATGTCGTTTGAAGATTTTAAGAAAAATTACACCAAAATTGAGATTTGTAACTTGACACCTGATGCCCTGGAGGACGATAAGCTACATAAGTGGACAGTGTCTGTCAATGAGGGCCGCTGGGTGAGAGGCTGCTCTGCCGGAGGATGCAGAAACTATCCAGACACATTCTGGACAAACCCACAATACCGTCTGCGTCTCCTGGAGGAAGATGACGATCCGGAGGATGATGAAGTGGCCTGCACATTTGTTGTTGCTCTAATGCAGAAAAACAGACGTAAAGAACGCAAGTTGGGTGCGAATCTCTTGACCATTGGATTTTCCATCTATGAGGTGCCAAAGGAGATGCATGGAAATAAGCAGCACATGCAGAAGGAGTTCTTCATGTCTACCACCGCTAAGGCTCGGTCCAGGGCCTACATTAACCTGCGCGAGGTCACCCAGCGTTTCCGTCTGAGTCCCGGAGAGTACGTCATCATTCCCTCTTCTTACGAGCCCCATCAGGAAGGCGAGTTCATCCTCCGCGTCTTCTCTGAAAAGAGAAATACTTCTGAGGAGATAGAGAACAGGATTGAAGCTGATCATCCAGTGCCTTCTCCGGCTTCAACTGGGGAGGAGAGCGAAGAGGACCAACAGTTCCTGTCCATTTTCCAGCACATCGCGGGGGACGTGAGTACTGGGGAGGCAGTGAGCGCTTGGGGGAGTAACATGGAGGTCTCTGCCAACGAGCTTAAAGATGTCTTGAACAAGGTGGTGTCTAAacACAAGGACATTCACACCGAGAGCTTCAGTCGAGAGTGCTGTAGAAGCATGATTGCCCTCATGGACATGGATGGAACAGGAAGACTTAACCTGCAAGAGTTTAGACAATTGTGGAACAAAATCAAACAGTGGCAGGAAATCTTTAAGCGCTATGACTTTGATCATAATGACACTATCAGCAGCTATGAGATGAGAAACGCCATCAATGACGCAGGGTTCCGTCTGAACAACCAGCTGTATGACATCATCACCATGCGCTACGCCAACGAAAGCATGAATGTCGACTTTGAGAGTTTCATCAGCTGCCTTGTGCGACTGGAGGGGATGTTCAGAGCATTCCAGGCCTTTGACCAATGTGGAGATGGCAGCATCAGGCTCAGTGTACTGGAGTGGCTCCAGCTAACCATGTACGCGTAGGCAAGCTACAGATCCAGGTGAGCCCGGACTTGGCAAGGACCAGAACTACCAGCTTTTACCTCAACACTCAATGCTGCCAGACTACTGTTACCTCTTTCTCTGTACCTCAGCTCAACACGACTGCCCCTctacatttatcatttatagaGGGTAAGACGGGTCTAATGTTGGCGGGCAGCACATTTGAGGCAATCTTTCAGGGGCACTGTGCGCAAGCAGCTTTTGAGGCATAAGTCATCCTCAGACGATCTTCTGTCATAACTTGTTCTTTGAAGTCATTACACATGAACTGCATTCAGTTTGTCTACACTAGTGTCACAGGCAGCGTTTCTCGCTTTTCCTCAGCTAGCCTCAAAAACGCTTATGTATTATAGCCCTGAAATTCCTCTCTGCTATATGCTGATGGAGCCAATAAACTATAgataacaatataaataactCAATAGTTAAAATAGGAAGGAATTGAAGTCAAGTAGATTTGGATATAACCTTCAACAATATCACTTACTGATACAACTGACTACTTAAATTGACCTTTCATACTGAAAAACAGCCAAAATTTGATCCACATTTGAATGCGGAGTTAGTTCTACACTTAGAAATCATGACAACATCCCTTTATCAGAGAATGCCTTTCCATCTTCACCTCGACTCGACGTGCTGTCCATCCCAACTTCTCAGTCATGATTTGGTGATATCATTTAGGAAATAAAGCATACATCATTTGTTCCCCCTTTCAAATCCTGGTTGTTTGGGAGACAGGAACATGGTGAAGAAGGAGGATCATAAAAAACTGAAGGAGGAGGAGAATCATGGATCTCAAAACCTCAAAGCTCATGATGGACGGCAACATTCAGGGTCTTACCTTAATTACTGTGGGTGAAGATATGGGTCGAACCtaggctttttttgtgtgtgtgtgcttgaccCTCATTTAACCTATTGTACAAATGAGTGTACTGACTTTACcttgtttaactgaataaatcaTTGTGTAGTTCTTGGCTG

Function

symbol description
capn3a Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in negative regulation of apoptotic process and proteolysis. Predicted to act upstream of or within sarcomere organization. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; endoderm; lens; liver; and solid lens vesicle. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; and muscular dystrophy. Orthologous to human CAPN3 (calpain 3).

GO:

id name namespace
GO:0043066 negative regulation of apoptotic process biological_process
GO:0045214 sarcomere organization biological_process
GO:0006508 proteolysis biological_process
GO:0005737 cytoplasm cellular_component
GO:0004198 calcium-dependent cysteine-type endopeptidase activity molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040912-97 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in negative regulation of apoptotic process and proteolysis. Predicted to act upstream of or within sarcomere organization. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; endoderm; lens; liver; and solid lens vesicle. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; and muscular dystrophy. Orthologous to human CAPN3 (calpain 3).

Ensembl:

ensembl_id ENSDARG00000041864

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00023198 True 3218 mRNA 0.47 21 45305645 45346635

Neighbor

gene id symbol gene type direction distance location
XLOC_011689 ganc coding upstream 2683 45259259 ~ 45302962 (+)
XLOC_011688 NA coding upstream 105104 45193180 ~ 45200541 (+)
XLOC_011687 CU695222.2 coding upstream 124899 45177626 ~ 45180746 (+)
XLOC_011686 gstz1 coding upstream 191126 45106424 ~ 45114519 (+)
XLOC_011685 coq6 coding upstream 275620 45009868 ~ 45030025 (+)
XLOC_011691 NA coding downstream 1388 45348023 ~ 45349995 (+)
XLOC_011692 nenf coding downstream 49211 45395846 ~ 45402961 (+)
XLOC_011693 tagapa coding downstream 58123 45404758 ~ 45411170 (+)
XLOC_011694 ezra coding downstream 66689 45413324 ~ 45452116 (+)
XLOC_011695 kcnk3b coding downstream 108308 45454943 ~ 45459207 (+)
XLOC_011683 NA non-coding upstream 542235 44761624 ~ 44763410 (+)
XLOC_011678 NA non-coding upstream 912858 44382333 ~ 44392787 (+)
XLOC_011677 BX548045.2 non-coding upstream 1014125 44291405 ~ 44291520 (+)
XLOC_011702 dre-mir-203a non-coding downstream 461518 45808153 ~ 45808248 (+)
XLOC_011704 NA non-coding downstream 826044 46172679 ~ 46180237 (+)
XLOC_011706 NA non-coding downstream 1109155 46455790 ~ 46464176 (+)
XLOC_011708 NA non-coding downstream 1396661 46743296 ~ 46825416 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000315_01058264_01077622 CAPN3, CAPN3A coding CI01000315 null 1058264 ~ 1077622 (+)