XLOC_011778 (dlst)


Basic Information

Item Value
gene id XLOC_011778
gene name dlst
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 52524355 ~ 52553447 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00023329
GCACAGAATGACAGCTCAATGGCACGTTCCATTCATGCTCCCCCCGCTCCACCTCATGATGGGTAACAGTGTTCTCGCAAGACGGGCTACATCAGGTATAGCAGCTAGTCAGTGTGTCAGCTTCCAGAACAGCCCGAGGTGTGAGACCCGCTCTAGTGTCTATCAGATCAGATACTTCAAGACCACAGCTGCTCACAGGAATGAAGTCATTACAGTAAAAACCCCAGCGTTTGCGGAGTCTGTCACAGAGGGAGATGTCAGGTGGGAGAAAGctgTTGGAGACTCAGTCGCTGAGGATGAGGTCGTCTGTGAAATCGAGACCGATAAGacgTCAGTGCAGGTCCCCTCTCCGGCTGCAGGAGTGATCGAGGAGCTGCTCGTTCCTGATGGAGGAAAAGTGGAAGGAGGAACTCCTCTGTTCAAGCTCAAGAAAGGAGCTGGAGCGGTGAAGACGGCAGCAGCGGCGGCGGCTCCTCCTCCAGCAGCAGAGACCCCTGCTCCTGCAGCCCCTGCCCCTGCTGCTGCCCCTGCGGGTGGACCCATACCCTCCAGCATGCCTCCTGTGCCCGCTGTGCCAGCCCAGCCCATCCAGGCCAAACCAGTTTCAGCCATCAAACCCACTGCTGCtgctcctgctgctgctgctgcagacACTGGAGCTAAAGCTCCCCGATCAGAGCACAGGGTGAAGATGAACCGCATGCGACTGCGAATCGCTCAGCGGC
>TCONS_00024790
GCACAGAATGACAGCTCAATGGCACGTTCCATTCATGCTCCCCCCGCTCCACCTCATGATGGGTAACAGTGTTCTCGCAAGACGGGCTACATCAGGTATAGCAGCTAGTCAGTGTGTCAGCTTCCAGAACAGCCCGAGGTGTGAGACCCGCTCTAGTGTCTATCAGATCAGATACTTCAAGACCACAGCTGCTCACAGGAATGAAGTCATTACAGTAAAAACCCCAGCGTTTGCGGAGTCTGTCACAGAGGGAGATGTCAGGTGGGAGAAAGctgTTGGAGACTCAGTCGCTGAGGATGAGGTCGTCTGTGAAATCGAGACCGATAAGacgTCAGTGCAGGTCCCCTCTCCGGCTGCAGGAGTGATCGAGGAGCTGCTCGTTCCTGATGGAGGAAAAGTGGAAGGAGGAACTCCTCTGTTCAAGCTCAAGAAAGGAGCTGGAGCGGTGAAGACGGCAGCAGCGGCGGCGGCTCCTCCTCCAGCAGCAGAGACCCCTGCTCCTGCAGCCCCTGCCCCTGCTGCTGCCCCTGCGGGTGGACCCATACCCTCCAGCATGCCTCCTGTGCCCGCTGTGCCAGCCCAGCCCATCCAGGCCAAACCAGTTTCAGCCATCAAACCCACTGCTGCtgctcctgctgctgctgctgcagacACTGGAGCTAAAGCTCCCCGATCAGAGCACAGGGTGAAGATGAACCGCATGCGACTGCGAATCGCTCAGCGGCTGAAGGAAGCGCAGAACACCTGTGCCATGCTGACCACCTTCAATGAAGTCGATATGAGCAACATCACAGAGATGAGGACACATTATAAAGATGCTTTCCTGAAGAAACACGGCATCAAGCTGGGCTTCATGTCTGCCTTCGTCAAAGCTGCAGCCTACGCTCTAACAGACCAGCCTGCCGTTAATGCTGCTTGTCATAAAGTTTTCTGGCAATTTTTGAGTTGTTCAGTGCTGTTCAGTGAGCTTGTTTTGATCTGTGCAGTCATTGATGACACAACCAAAGAGATCGTGTATCGGGATTATGTGGACATCAGTGTGGCGGTGGCGACACCAAAGggtCTGGTGGTGCCGGTGATCAGAGGTGTGGAGGGAATGAACTTTGCAGACATCGAGAAGACCATTAATGAGCTGGGAGAGAAGGCCCGTAAGAATGAGCTGGCTGTGGAGGATATGGATGGAGGCACGTTTACCATCAGCAATGGAGGAGTTTTCGGCTCCATGTTCGGAACTCCAATCATCAACCCGCCACAGTCTGCCATCCTGGGCATGCATGGCATCTTCGACCGGCCTGTGGCCATCGCTGGCAAGGTGGAGGTGCGGCCGATGATGTACGTGGCTCTGACCTACGACCACCGCTTGATTGACGGCAGAGAGGCGGTCACTTTCCTCA
>TCONS_00023330
GTTTCCGCTGCTGTGCCGTGAGAGCTGCAGTGCGCGCGGTTCACCGACGACATGTTGTGTCATTCCCGCTGTCTGAGCCGGAGCCTCGGCCGCTCGATCACCGCCCTGAGACAGGGTAACAGTGTTCTCGCAAGACGGGCTACATCAGGTATAGCAGCTAGTCAGTGTGTCAGCTTCCAGAACAGCCCGAGGTGTGAGACCCGCTCTAGTGTCTATCAGATCAGATACTTCAAGACCACAGCTGCTCACAGGAATGAAGTCATTACAGTAAAAACCCCAGCGTTTGCGGAGTCTGTCACAGAGGGAGATGTCAGGTGGGAGAAAGctgTTGGAGACTCAGTCGCTGAGGATGAGGTCGTCTGTGAAATCGAGACCGATAAGacgTCAGTGCAGGTCCCCTCTCCGGCTGCAGGAGTGATCGAGGAGCTGCTCGTTCCTGATGGAGGAAAAGTGGAAGGAGGAACTCCTCTGTTCAAGCTCAAGAAAGGAGCTGGAGCGGTGAAGACGGCAGCAGCGGCGGCGGCTCCTCCTCCAGCAGCAGAGACCCCTGCTCCTGCAGCCCCTGCCCCTGCTGCTGCCCCTGCGGGTGGACCCATACCCTCCAGCATGCCTCCTGTGCCCGCTGTGCCAGCCCAGCCCATCCAGGCCAAACCAGTTTCAGCCATCAAACCCACTGCTGCtgctcctgctgctgctgctgcagacACTGGAGCTAAAGCTCCCCGATCAGAGCACAGGGTGAAGATGAACCGCATGCGACTGCGAATCGCTCAGCGGCTGAAGGAAGCGCAGAACACCTGTGCCATGCTGACCACCTTCAATGAAGTCGATATGAGCAACATCACAGAGATGAGGACACATTATAAAGATGCTTTCCTGAAGAAACACGGCATCAAGCTGGGCTTCATGTCTGCCTTCGTCAAAGCTGCAGCCTACGCTCTAACAGACCAGCCTGCCGTTAATGCTGTCATTGATGACACAACCAAAGAGATCGTGTATCGGGATTATGTGGACATCAGTGTGGCGGTGGCGACACCAAAGggtCTGGTGGTGCCGGTGATCAGAGGTGTGGAGGGAATGAACTTTGCAGACATCGAGAAGACCATTAATGAGCTGGGAGAGAAGGCCCGTAAGAATGAGCTGGCTGTGGAGGATATGGATGGAGGCACGTTTACCATCAGCAATGGAGGAGTTTTCGGCTCCATGTTCGGAACTCCAATCATCAACCCGCCACAGTCTGCCATCCTGGGCATGCATGGCATCTTCGACCGGCCTGTGGCCATCGCTGGCAAGGTGGAGGTGCGGCCGATGATGTACGTGGCTCTGACCTACGACCACCGCTTGATTGACGGCAGAGAGGCGGTCACTTTCCTCAGGAAGATCAAGTCTGTGGTGGAGGACCCGCGGGTGCTGCTGCTGGACATGTAATGCGGCTCCACCAATCGCAGCGCAGATACACTAGAGGAACACACACGTCACCCGTAGAGTAAATCAGCGGCGGAGTGGAGTGAGGTTTGCATTGATTAGCTTCATGTTGTTTTACCGTGTCAATGTCTGCTGGGTTTGCGGAAGATTCTGGAGTTTGTGTGGCCCTCGCGGGAAGCCGTCTCGCGCTGTCCTGTTCTCGTATGCGCACAGAAAACATGACCCGTGCAATTTGTTTCTTAATGAAATGAGCGTAATATACCATAAATGATATTTAATCTCTTCTGTGTCAAAGAAAACAAAGTAAACAAGGTTATTTGATCCGCTCGGCAGAAACACTATGTTCTTTTGTACACCTCGACGTGTCTCGCACAACTCCAGGCCATCCCATTCTGTCTGCCCTTGTAAAGAACCAAAAAATATATGagattttaaacaataaaatcaaaGAAATGCTCAGCAGA
>TCONS_00023331
AGGTATAGCAGCTAGTCAGTGTGTCAGCTTCCAGAACAGCCCGTGAGTGTCTCTGAGCTCTGACATTTCCTATGGATGCGGATAAAATGTAAGATCTCACCACACTGTGTGTTTTTCAGGAGGTGTGAGACCCGCTCTAGTGTCTATCAGATCAGATACTTCAAGACCACAGCTGCTCACAGGAATGAAGTCATTACAGTAAAAACCCCAGCGTTTGCGGAGTCTGTCACAGAGGGAGATGTCAGGTGGGAGAAAGGTAAGAAGGCAACATGTTTTTCCTTGTTTCTTCAATAAATCGACGCTATAAATGAATCTTGCAGCTTTAAACGTATTAGTAAAAATATGAgttaaattaaagggatagttcacccaaaaatcaaaatgTCCTCACTATATGCACTACCTCAagtgctcattcattttcctttggcttagtctcttatttatcaggggtcaccacagcggaatgaaccaccaactattccagcatatgttttacgcagcggatgccctttaatccccaacccagtactggaaaacacacattcatgcacaaaagccaatttagctcatcaatTCTcccatagcacatgtgtttggactgtgggggaaactggagcacccggtggaaacccacgccaacacggggagaacatgcaaactccacacagaaacagcccCTGTAGgcactcgaaccagccacctt
>TCONS_00023332
tcctgctgctgctgctgcagacACTGGAGCTAAAGCTCCCCGATCAGAGCACAGGGTGAAGATGAACCGCATGCGACTGCGAATCGCTCAGCGGCTGAAGGAAGCGCAGAACACCTGTGCCATGCTGACCACCTTCAATGAAGTCGATATGAGCAACATCACAGAGATGAGGACACATTATAAAGATGCTTTCCTGAAGAAACACGGCATCAAGCTGGGCTTCATGTCTGCCTTCGTCAAAGCTGCAGCCTACGCTCTAACAGACCAGCCTGCCGTTAATGCTGCTTGTCATAAAGTTTTCTGGCAATTTTTGAGTTGTTCAGTGCTGTTCAGTGAGCTTGTTTTGATCTGTGCAGTCATTGATGACACAACCAAAGAGATCGTGTATCGGGATTATGTGGACATCAGTGTGGCGGTGGCGACACCAAAGggtCTGGTGGTGCCGGTGATCAGAGGTGTGGAGGGAATGAACTTTGCAGACATCGAGAAGACCATTAATGAGCTGGGAGAGAAGGCCCGTAAGAATGAGCTGGCTGTGGAGGATATGGATGGAGGCACGTTTACCATCAGCAATGGAGGAGTTTTCGGCTCCATGTTCGGAACTCCAATCATCAACCCGCCACAGTCTGCCATCCTGGGCATGCATGGCATCTTCGACCGGCCTGTGGCCATCGCTGGCAAGGTGGAGGTGCGGCCGATGATGTACGTGGCTCTGACCTACGACCACCGCTTGATTGACGGCAGAGAGGCGGTCACTTTCCTCA

Function

symbol description
dlst Predicted to enable dihydrolipoyllysine-residue succinyltransferase activity. Acts upstream of or within several processes, including ATP biosynthetic process; heart contraction; and mitochondrion morphogenesis. Predicted to be part of oxoglutarate dehydrogenase complex. Is expressed in several structures, including immature eye; musculature system; nervous system; neural plate; and segmental plate. Human ortholog(s) of this gene implicated in Alzheimer's disease and paraganglioma. Orthologous to human DLST (dihydrolipoamide S-succinyltransferase).

GO:

id name namespace
GO:0030097 hemopoiesis biological_process
GO:0006099 tricarboxylic acid cycle biological_process
GO:0070584 mitochondrion morphogenesis biological_process
GO:0006754 ATP biosynthetic process biological_process
GO:0060047 heart contraction biological_process
GO:0045252 oxoglutarate dehydrogenase complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function
GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity molecular_function

KEGG:

id description
ko00020 Citrate cycle (TCA cycle)
ko00310 Lysine degradation
ko00380 Tryptophan metabolism

ZFIN:

id description
ZDB-GENE-030326-1 Predicted to enable dihydrolipoyllysine-residue succinyltransferase activity. Acts upstream of or within several processes, including ATP biosynthetic process; heart contraction; and mitochondrion morphogenesis. Predicted to be part of oxoglutarate dehydrogenase complex. Is expressed in several structures, including immature eye; musculature system; nervous system; neural plate; and segmental plate. Human ortholog(s) of this gene implicated in Alzheimer's disease and paraganglioma. Orthologous to human DLST (dihydrolipoamide S-succinyltransferase).

Ensembl:

ensembl_id ENSDARG00000014230

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00023329 False 725 processed_transcript 0.58 10 52524355 52537436
TCONS_00024790 False 1394 lncRNA 0.55 15 52524355 52552933
TCONS_00023330 False 1889 mRNA 0.54 15 52524452 52553447
TCONS_00023331 False 706 processed_transcript 0.45 2 52528498 52531702
TCONS_00023332 True 764 processed_transcript 0.53 7 52534566 52552933

Neighbor

gene id symbol gene type direction distance location
XLOC_011777 NA coding upstream 50264 52473758 ~ 52474091 (+)
XLOC_011776 esrrb coding upstream 137837 52300018 ~ 52386518 (+)
XLOC_011775 NA coding upstream 251838 52271297 ~ 52272517 (+)
XLOC_011774 NA coding upstream 389316 52131296 ~ 52135039 (+)
XLOC_011773 NA coding upstream 393537 52129692 ~ 52130818 (+)
XLOC_011779 NA coding downstream 257 52553704 ~ 52590848 (+)
XLOC_011780 angel1 coding downstream 59419 52612866 ~ 52643968 (+)
XLOC_011781 NA coding downstream 104592 52658039 ~ 52662430 (+)
XLOC_011782 NA coding downstream 115527 52668974 ~ 52671734 (+)
XLOC_011783 NA coding downstream 213857 52767304 ~ 52792053 (+)
XLOC_011771 CU633997.1 non-coding upstream 616169 51908071 ~ 51908186 (+)
XLOC_011785 CABZ01078350.1 non-coding downstream 288383 52841830 ~ 52842772 (+)

Expression


Co-expression Network