XLOC_001181 (tll1)


Basic Information

Item Value
gene id XLOC_001181
gene name tll1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 20733102 ~ 20826023 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001881
cGTTAATCTCTAGGGAAATGGGCACGTTTGGAATAAGCGGTACCAGTCAGCTAGCGCACTCTAATATTCCAGTGGCTGTAGAAAAAGTgtttccagagagagagagagaagagagagggagggagagagagggaatATGAGGGCAGTACTCAGGATGAGCCTGCGCTTTGAGGCTGTAAAACACTAGACCCTGAGGGCATTCTCTGTCTGAGCTGTGCCTCTTCAGGAAAACTGACTGCGCAAGAGAAAGGAAGAGTGAGCTGGTATCCTCTGTAGTTGTAGGTTCATATTGATGCATTTGGCGTCCAGCTGAGATGCCGCGACGCTGACGGTCCTGCCCCGTCTGTCGAACCGGACCAATGATGATAATGAAGGCGATGATGTCCACACGGCGCGTGTAGCGCTAAATTCCACACTGCCGGACTCCTACCAGACACTCCTCTCTGACCCACGCTCGTTCACACCTCAGATGGACTACCTTTACTCTGCACTCACCAGTAAAATGAATTGGATCGCACTCCTGCTGGCCGGCTTGACTTTTTGTTGCAAAGTGTCCGTGCACAGCTGTTTAGATTACGATGACAGTTATGATTATTACGAGGAGGAGAAAACAGAGACAATAGACTACAAGGATCCCTGCAAAGCAGCTGTATTTTGGGGAGACATTGCCTTGGATGATGAGGACTTGAAAATGTTTCACATCGATGGGACGATAGACCTTAAGCAACAAACACATGGGAGGCAAGGACACACATCTGGAGGTCTAGGAGAACATGTGCCCACTAAGAAGAGGGGTTCCTTATATCTGCTGCTAGACAGAATACGACGGTTAGGTTTTGAGTCGTGGCCAgtaaacagcagtaaagatgtgTCAAGCATAAAGACTGGAATAAGGAGAGTAAACAGCGCCAGAAATGTAAAGTCTCGAGTCCCACGTGCTGCTACATCCCGAGCTGAGAAGATCTGGCCTGGAGGAGTCATCCCTTACGTCATAGGAGGCAACTTCACCGgaaGTCAGAGGGCCATGTTAAAGCAAGCAATGAGACACTGGGAGAAACAGACGTGCGTGACTTTCATAGAGAAGACTGATGAGGAGAGCTACATTGTCTTCACGTACAGACCTTGCGGGTGTTGCTCTTATGTCGGTCGCCGTGGAAATGGTCCCCAGGCAATATCTATAGGGAAAAACTGTGACAAGTTTGGCATTGTGGTTCATGAACTTGGGCATGTGATCGGCTTTTGGCATGAACACACACGACCTGACCGTGACGATCATGTGACCATCATCCGGGACAACATCCAGCCAGGTCAGGAGTATAACTTCATCAAGATGGAACCAGGGGATGTCAACTCTCTTGGTGAGCCGTATGATTTTGACAGCATCATGCATTATGCCAGAAACACTTTCTCCAGAGGAATGTTTTTGGACACGATTCTTCCCTCTCGTGACGAGAATGGCGTCAGGCCTGCTATTGGTCAGAGAACCAGGCTCAGTAAAGGGGATATATCGCAAGCCAAGAAGCTGTACAGATGCCCAGCATGTGGCGAAACACTACAGGACTCAGTGGGGAATTTCTCATCTCCAGGATATCCTAATGGATACCCATCATATACACACTGTGTATGGAGGATCTCTGTCACACCTGGGGAGAAGATAGTGTTAAACTTCACCACTATGGACCTCTACAAGAGCAGCCTGTGCTGGTATGACTACATTGAGGTTCGTGACGGATACTGGAGAAAAGCGCCATTGCTGGGCCGGTTCTGCGGTGATAAAATTCCAGAAGTTCTGGTCTCTACAGACAGTCGGATGTGGATTGAGTTTCGAAGCAGCAGCAACTGGGTTGGAAAGGGATTTGCAGCAGTCTATGAAGCAATATGTGGAGGGGAGATCAGTAAGGACTCTGGACAGATTCAGTCTCCAAACTATCCAGATGACTATCGCCCATCTAAGGAGTGTGTGTGGAGGATCACAGTGTCTGAGGGCTACAGCGTGGGCTTAAGCTTTCAGGTTTTTGAGATCGAGAGGCATGACAGCTGTGCATACGACTATTTGGAGGTTAGAGATGGATTGTCAGAGAACAGCCCTCTGATTGGTCGATTCTGCGGCTATGATAAACCTGAAGATATTCGTTCTACCTCTAACAACCTCTGGATGAAATTTGTCTCTGATGGGACTGTTAATAAAGCAGGCTTTGCTGCAAACTTCTTCAAAGAGGAAGACGAGTGTCTGAAGCCAGATAATGGAGGCTGTGAACAGAGATGTGTGAACACATTAGGAAGCTTCAAATGTGCATGTGATCCTGGATATGAACTGGCTCCTGACAAGAAGAGCTGTGAagCTGCGTGTGGCGGTTTGTTGACTAAGTTGAATGGCACAATTACCACCCCAGGCTGGCCTAAGGAATACCCTCCCAACAAAAACTGTGTGTGGCAAGTAGTGGCCCCGACTCAGTACCGTATATCCATGCAGTTTGAAGCCTTTGAGCTGGAGGGAAATGAGGTGTGCAAGTATGACTACGTCGAGGTGCGGAGCGGCTTGTCATCTGACTCAAAGCTTCATGGGAAATACTGCGGCACGGAAGTTCCTGAGGTCATCACCTCCCAGTACAACAACATGCGAATCGAGTTCAAATCAGACAACACGGTCTCCAAGAAAGGCTTCAAAGCTCATTTTTTCTCCGATAAAGACGAATGTTCAAAGGATAACGGTGGATGCCAGCATGAGTGCATCAACACTATTGGCAGCTATGTGTGCCAGTGCCGCAACGGCTTCATCCTACATGAGAACAAACATGACTGCAAGGAAGctgagtgtgagcACAAAATCCACAGCACGACTGGAACCATCAGCAGTCCAAACTGGCCTGACAAATACCCCAGCAGAAAGGAGTGCACGTGGGACATCACCGCAACCCCTGGTCACCGGGTCAAAATTTCTTTTAATGAATTTGAGATTGAGCAGCACCAGGAATGCGCATATGATCACCTGGAGGCCTTTGACGGCGATTCAGACAAGACTCCTATACTGAGTCGCCTGTGTGGCAATAAGATTCCCGAACCACTCATTTCCACTGGCAACAAGATGTATCTGCGTTTCATCTCCGATGCCTCAGTTCAACGGAAAGGCTTTCAGGCCACTCATTCCACCGAATGTGGCGGAAGGCTGAAAGCAGAAGCACGACAGAAGAACCTGTATTCTCATGCTCAGTTTGGAGATAATAACTACCCCGGACACACCGACTGCGAGTGGCTCATAGTGGCAGAGTCGGGTTATGGCATCGAACTCACCTTCACCACCTTTGAGGTAGAAGAAGAGGCAGACTGTGGGTACGACTACATCGAACTTTACGATGGTTACGACACTGGAGCGCACAAAATCGGACGCTTCTGTGGATCTGGGCCTCGTGAGGAGCTTTACTCTGCTGGCGATGCCGTGTTGATCCATTTTCACTCTGACGACACCATCAGTAAGAAAGGCTTTCACATCCGCTACACTAGCACAAAGTTTCAGGAGGCGCTACACACACGCAAGTAACATTTGAGAGACTGAAGACAGGGATAAAATGAGGAGAAAAAGACTCCAGCAAACTATTGCAATTGATTCATTTCAATCAAAGACCCTGCCGTTATGTGTTTTCTGCATTGGATTTGCCTCTATGTTCAGCCACTATGGAAGTGCTGTCATATTGACCCTAAACACCAATCAGCTGCTCTTATGTGTGGGATTGCTCCGCCCACTGGAGTGGTGTCTTGCGCTCTCTGACTGGAGCAGTgcagtgaaaacacacacacacaatcacacacaaaacTTTCTTGTTGGCTCTCCATTCTTCAGACATAGAGTTGCACACTGAAACTAAGAGACACTGATAATAAGACATTTAAGTAACTGCTattgaacgtgtgtgtgtgtatgtgtgtgtgttgctccgGACAGCATGGACAGTTTGGCTGCTGACGCCACACCACACTGTACCTCAgctaaaaatgtgtgtgtgtatttggatgtgtgtgattgagagaaaaacagaaagagagagagagaggccttCAAATACCAGCCTGAActcattcaaatgtttttttttaattgtggttGTACAATTCTTCTGTTATTGTTCTGTTAGCTTTACGGCAAAACCCATTTTCTCTCCATCAAAAGTGCAAAAGTAAATATGTAGCCCTATTTAACAATAAGCTTCCTTACATGTATGTAGCCCATTGTTTATGTCAGCGGAGACAGACATCATTTGTCAGTGAACTATTAAGCTGGAGGGTCTCATTCACTAAGTATCTGCATGCATCAACTGGTGAGGGAAATTTCCAacccattctgaaaatgtacctttatatacatttctggagagcgccaaatacgtcccaggagctacgtttttgtcagtttttgtttttgcgaatccaccagaggctgctgtgtatgctttttgagatcttaaatttctctcaccattgccattcacacctgctgttctcttgtaaatccaccagagcccGCTGTTGACTGACTTTCTGGCTGACCAATCAacttgacccaccctcctcctttcctaaacctaaccaatagtattttaaaaagcacagattgacctgcccacccacttccctaaac
>TCONS_00001882
TGCCGGACTCCTACCAGACACTCCTCTCTGACCCACGCTCGTTCACACCTCAGATGGACTACCTTTACTCTGCACTCACCAGTAAAATGAATTGGATCGCACTCCTGCTGGCCGGCTTGACTTTTTGTTGCAAAGTGTCCGTGCACAGCTGTTTAGATTACGATGACAGTTATGATTATTACGAGGAGGAGAAAACAGAGACAATAGACTACAAGGATCCCTGCAAAGCAGCTGTATTTTGGGGAGACATTGCCTTGGATGATGAGGACTTGAAAATGTTTCACATCGATGGGACGATAGACCTTAAGCAACAAACACATGGGAGGCAAGGACACACATCTGGAGGTCTAGGAGAACATGTGCCCACTAAGAAGAGGGGTTCCTTATATCTGCTGCTAGACAGAATACGACGGTTAGGTTTTGAGTCGTGGCCAgtaaacagcagtaaagatgtgTCAAGCATAAAGACTGGAATAAGGAGAGTAAACAGCGCCAGAAATGTAAAGTCTCGAGTCCCACGTGCTGCTACATCCCGAGCTGAGAAGATCTGGCCTGGAGGAGTCATCCCTTACGTCATAGGAGGCAACTTCACCGgaaGTCAGAGGGCCATGTTAAAGCAAGCAATGAGACACTGGGAGAAACAGACGTGCGTGACTTTCATAGAGAAGACTGATGAGGAGAGCTACATTGTCTTCACGTACAGACCTTGCGGGTGTTGCTCTTATGTCGGTCGCCGTGGAAATGGTCCCCAGGCAATATCTATAGGGAAAAACTGTGACAAGTTTGGCATTGTGGTTCATGAACTTGGGCATGTGATCGGCTTTTGGCATGAACACACACGACCTGACCGTGACGATCATGTGACCATCATCCGGGACAACATCCAGCCAGGTCAGGAGTATAACTTCATCAAGATGGAACCAGGGGATGTCAACTCTCTTGGTGAGCCGTATGATTTTGACAGCATCATGCATTATGCCAGAAACACTTTCTCCAGAGGAATGTTTTTGGACACGATTCTTCCCTCTCGTGACGAGAATGGCGTCAGGCCTGCTATTGGTCAGAGAACCAGGCTCAGTAAAGGGGATATATCGCAAGCCAAGAAGCTGTACAGATGCCCAGCATGTGGCGAAACACTACAGGACTCAGTGGGGAATTTCTCATCTCCAGGATATCCTAATGGATACCCATCATATACACACTGTGTATGGAGGATCTCTGTCACACCTGGGGAGAAGATAGTGTTAAACTTCACCACTATGGACCTCTACAAGAGCAGCCTGTGCTGGTATGACTACATTGAGGTTCGTGACGGATACTGGAGAAAAGCGCCATTGCTGGGCCGGTTCTGCGGTGATAAAATTCCAGAAGTTCTGGTCTCTACAGACAGTCGGATGTGGATTGAGTTTCGAAGCAGCAGCAACTGGGTTGGAAAGGGATTTGCAGCAGTCTATGAAGCAATATGTGGAGGGGAGATCAGTAAGGACTCTGGACAGATTCAGTCTCCAAACTATCCAGATGACTATCGCCCATCTAAGGAGTGTGTGTGGAGGATCACAGTGTCTGAGGGCTACAGCGTGGGCTTAAGCTTTCAGGTTTTTGAGATCGAGAGGCATGACAGCTGTGCATACGACTATTTGGAGGTTAGAGATGGATTGTCAGAGAACAGCCCTCTGATTGGTCGATTCTGCGGCTATGATAAACCTGAAGATATTCGTTCTACCTCTAACAACCTCTGGATGAAATTTGTCTCTGATGGGACTGTTAATAAAGCAGGCTTTGCTGCAAACTTCTTCAAAGAGGAAGACGAGTGTCTGAAGCCAGATAATGGAGGCTGTGAACAGAGATGTGTGAACACATTAGGAAGCTTCAAATGTGCATGTGATCCTGGATATGAACTGGCTCCTGACAAGAAGAGCTGTGAagCTGCGTGTGGCGGTTTGTTGACTAAGTTGAATGGCACAATTACCACCCCAGGCTGGCCTAAGGAATACCCTCCCAACAAAAACTGTGTGTGGCAAGTAGTGGCCCCGACTCAGTACCGTATATCCATGCAGTTTGAAGCCTTTGAGCTGGAGGGAAATGAGGTGTGCAAGTATGACTACGTCGAGGTGCGGAGCGGCTTGTCATCTGACTCAAAGCTTCATGGGAAATACTGCGGCACGGAAGTTCCTGAGGTCATCACCTCCCAGTACAACAACATGCGAATCGAGTTCAAATCAGACAACACGGTCTCCAAGAAAGGCTTCAAAGCTCATTTTTTCTCCGATAAAGACGAATGTTCAAAGGATAACGGTGGATGCCAGCATGAGTGCATCAACACTATTGGCAGCTATGTGTGCCAGTGCCGCAACGGCTTCATCCTACATGAGAACAAACATGACTGCAAGGAAGctgagtgtgagcACAAAATCCACAGCACGACTGGAACCATCAGCAGTCCAAACTGGCCTGACAAATACCCCAGCAGAAAGGAGTGCACGTGGGACATCACCGCAACCCCTGGTCACCGGGTCAAAATTTCTTTTAATGAATTTGAGATTGAGCAGCACCAGGAATGCGCATATGATCACCTGGAGGCCTTTGACGGCGATTCAGACAAGACTCCTATACTGAGTCGCCTGTGTGGCAATAAGATTCCCGAACCACTCATTTCCACTGGCAACAAGATGTATCTGCGTTTCATCTCCGATGCCTCAGTTCAACGGAAAGGCTTTCAGGCCACTCATTCCACCGAATGTGGCGGAAGGCTGAAAGCAGAAGCACGACAGAAGAACCTGTATTCTCATGCTCAGTTTGGAGATAATAACTACCCCGGACACACCGACTGCGAGTGGCTCATAGTGGCAGAGTCGGGTTATGGCATCGAACTCACCTTCACCACCTTTGAGGTAGAAGAAGAGGCAGACTGTGGGTACGACTACATCGAACTTTACGATGGTTACGACACTGGAGCGCACAAAATCGGACGCTTCTGTGGATCTGGGCCTCGTGAGGAGCTTTACTCTGCTGGCGATGCCGTGTTGATCCATTTTCACTCTGACGACACCATCAGTAAGAAAGGCTTTCACATCCGCTACACTAGCACAAAGTTTCAGGAGGCGCTACACACACGCAAGTAACATTTGAGAGACTGAAGACAGGGATAAAATGAGGAGAAAAAGACTCCAGCAAACTATTGCAATTGATTCATTTCAATCAAAGACCCTGCCGTTATGTGTTTTCTGCATTGGATTTGCCTCTATGTTCAGCCACTATGGAAGTGCTGTCATATTGACCCTAAACACCAATCAGCTGCTCTTATGTGTGGGATTGCTCCGCCCACTGGAGTGGTGTCTTGCGCTCTCTGACTGGAGCAGTgcagtgaaaacacacacacacaatcacacacaaaacTTTCTTGTTGGCTCTCCATTCTTCAGACATAGAGTTGCACACTGAAACTAAGAGACACTGATAATAAGACATTTAAGTAACTGCTattgaacgtgtgtgtgtgtatgtgtgtgtgttgctccgGACAGCATGGACAGTTTGGCTGCTGACGCCACACCACACTGTACCTCAgctaaaaatgtgtgtgtgtatttggatgtgtgtgattgagagaaaaacagaaagagagagagagaggccttCAAATACCAGCCTGAActcattcaaatgtttttttttaattgtggttGTACAATTCTTCTGTTATTGTTCTGTTAGCTTTACGGCAAAACCCATTTTCTCTCCATCAAAAGTGCAAAAGTAAATATGTAGCCCTATTTAACAATAAGCTTCCTTACATGTATGTAGCCCATTGTTTATGTCAGCGGAGACAGACATCATTTGTCAGTGAACTATTAAGCTGGAGGGTCTCATTCACTAAGTATCTGCATGCATCAACTGGTGAGGGAAATTTCCAacccattctgaaaatgtacctttatatacatttctggagagcgccaaatacgtcccaggagc

Function

symbol description
tll1 Enables metallopeptidase activity. Acts upstream of or within several processes, including determination of ventral identity; embryonic morphogenesis; and post-anal tail morphogenesis. Is expressed in margin; neural plate; tail bud; vascular cord; and vasculature. Human ortholog(s) of this gene implicated in atrial heart septal defect 6. Orthologous to human TLL1 (tolloid like 1).

GO:

id name namespace
GO:0001707 mesoderm formation biological_process
GO:0036342 post-anal tail morphogenesis biological_process
GO:0007275 multicellular organism development biological_process
GO:0048264 determination of ventral identity biological_process
GO:0030513 positive regulation of BMP signaling pathway biological_process
GO:0001568 blood vessel development biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0035124 embryonic caudal fin morphogenesis biological_process
GO:0006508 proteolysis biological_process
GO:0001885 endothelial cell development biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0005576 extracellular region cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0005515 protein binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004222 metalloendopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-041020-1 Enables metallopeptidase activity. Acts upstream of or within several processes, including determination of ventral identity; embryonic morphogenesis; and post-anal tail morphogenesis. Is expressed in margin; neural plate; tail bud; vascular cord; and vasculature. Human ortholog(s) of this gene implicated in atrial heart septal defect 6. Orthologous to human TLL1 (tolloid like 1).

Ensembl:

ensembl_id ENSDARG00000037429

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001881 False 4633 mRNA 0.47 22 20733102 20826023
TCONS_00001882 True 3975 mRNA 0.47 21 20733344 20824411
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Neighbor

gene id symbol gene type direction distance location
XLOC_001180 NA coding downstream 8751 20615209 ~ 20724351 (-)
XLOC_001179 ugt8 coding downstream 139324 20556067 ~ 20593778 (-)
XLOC_001178 NA coding downstream 179970 20459275 ~ 20553132 (-)
XLOC_001177 ndst3 coding downstream 459875 20147222 ~ 20273227 (-)
XLOC_001176 mettl14 coding downstream 664947 20063502 ~ 20068155 (-)
XLOC_001182 cpe coding upstream 13459 20839482 ~ 20911297 (-)
XLOC_001183 msmo1 coding upstream 90528 20916551 ~ 20928772 (-)
XLOC_001184 CT583646.1 coding upstream 103414 20929437 ~ 20930443 (-)
XLOC_001185 klhl2 coding upstream 106029 20932052 ~ 20970266 (-)
XLOC_001186 BX323083.1 coding upstream 154952 20980975 ~ 20986124 (-)
XLOC_001175 NA non-coding downstream 709363 20003654 ~ 20023739 (-)
XLOC_001173 BX323590.4 non-coding downstream 944891 19787281 ~ 19788211 (-)
XLOC_001171 NA non-coding downstream 1032144 19689644 ~ 19700958 (-)
XLOC_001187 BX323083.3 non-coding upstream 164854 20990877 ~ 20996026 (-)
XLOC_001188 BX323083.2 non-coding upstream 174761 21000784 ~ 21005933 (-)
XLOC_001189 BX323083.5 non-coding upstream 184666 21010689 ~ 21015930 (-)

Expression

Expression of XLOC_001181(tll1) in the Zebrafish Sample from each Developmental Stage of PRJEB12982

Boxplot with 18 boxes. Box plot charts are typically used to display groups of statistical data. Each data point in the chart can have up to 5 values: minimum, lower quartile, median, upper quartile, and maximum.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying Expression. Range: 0 to 15.
End of interactive chart.

Expression of XLOC_001181(tll1) in the Zebrafish Sample of PRJEB12982

Bar chart with 360 bars.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying Expression. Range: 0 to 15.
End of interactive chart.

Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000300_07619188_07667913 TLL1, TLL1.S coding CI01000300 null 7619188 ~ 7667913 (-)