XLOC_012329 (egr2a)


Basic Information

Item Value
gene id XLOC_012329
gene name egr2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 43663504 ~ 43677471 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00024252
AAAACCCCGACTGGAACATATTTACTGGAAAAGTCATTATAAAGTCTAATTTATATGAATATTAGCAAAATAATCTATAATATTCCCACTTTTTTGCTGTCAAAAGTGAATTTTGCAAAcctattttgtgaagaaaaaaccAAGAATCCtttattgaagtttttttttttctgctgtgacGAAATTGTCCAAACAATAGCCTAATTCCTTTCCATAACTTTTGTATAACCTGGTAATATTTCTTATAGAGGTTCTTTTGGAAATACAGATCCAAATAAAATACGAGTTATTAGGTTTTTTAAATACGTAATTAATAAACAGAGTAAAAATGTGACTTCTAGCCTTAAATCGTCCATGTATTTTTCAATCTTATTTTAACAGCAAGGAAATTCGTAGTATCACAAAATATTTTGCTGTGATTTTAAACCAGAATATTGAGACACCCGCATATATTTACCCTCCAACACACCAACAATCTTTTGAAATCAAATAGCTTACTGAATAGAGCTGCTATCACGTGGTGGAAACGCAGTCTGCTCTTTTAGACGTTTACACCAAAACATATTACTGAGTTTCTCTATAAGCCTGTTGCTTTTTGCTCATACAGGTGGCCTGAGCAGCGACAGCTTCGGCGTGGAAAAGCGGGACCTTGATCTGCCTGACCCGGGCAAGTTTTCTCCGCACAGCGCGCCTGTCGCCTACACGGGGAAAATTTCCATCGACGCGCAGGGAAGTTGGAGTCAAGAGGGAATAATCAACTTCATCAGTGCAGGAGTGCAGGACCGGTCCACATCACCAGGATCGTTCTCCACGGGCTCGCCCGCAGGTCCACCTTCAGACTGCTCCAAAATAGTCCAAAATCTTCCCAACATGGAGCACATGTACACAGGGCCACCCCCTTACACCTGTAGCGCCGAGGGCTATCAGGACCCTTCGGTCTACCTGTCGACCACTACATGCCCAATAACATACGCACCTCCGTCATACTCGGCCCCAAAATCAACCATAGACGGGGCGCTTTTCTCCATCATTCCCGATTATGGGGGCTTTTATCAGAACAGCAGCTGCCAAAGGGACAACATGGCAGTTTTTCAGGATATCAAGCCGTTTTCGTGCTCTTTGGAGTCTATTAGAGTCCCACCACCTCTGACTCCCTTGAACACTATAAGGAATTTTACTCTGGCGTGTCCGGTGGACGGCTCAAGGCCGCCGTTAGACGGCACCAACCCGCAGAATGTCCCACTCAGGCCAATACTGCGGCCACGGAAATACCCGAACCGACCGTGCAAGACGCCGGTGCACGAGCGCCCGTATCCGTGTCCGGCCGAGGGATGCGACCGGAGGTTTTCGCGCTCGGATGAGCTCACGCGTCACGTCCGCATCCACACCGGACACAAGCCGTTTCAGTGCCGCATCTGCATGCGCAGCTTCAGCCGGAGCGACCACCTCACGACCCACATCCGCACACACACGGGCGAGAAGCCCTTCTCCTGTGACTTCTGCGGCAGAAAGTTCGCCCGAAGCGACGAGCGAAGGAGGCACACAAAAATCCACCAGAGACATAAGGACAGAAAGCTTTCTGTGGGCCCTCACAGCTCCAGCGCTGGGGGAAACTGATTAGATAGCACATACATGATGTGACCCCTGGGTTCGTCAACCTGGACCTTGTTTGTGTGCACACAAAAAAATACGAAGGCAGCTTATGAATCTTAATGTTGAATGTGGTTTGTTGTAGAAGCTAGTCGTTATCACAGAATATTTCATGTGGTGCATAATGCAGTTGTTCTGAGAAATAGTGTTTACAGTGAGTCTTTTTGTTGACTATTATTGTTACGTGtcttaataaaatgataataaacacAA
>TCONS_00024253
agaagaggaggaagaagaagaagaagaagaagaaagagcTGAAGCAGGAGAAAAAGCTGATCGCTGATGTTTCACACACACATCCTCAGCTGAGAGAAGCCGATGCTGATGGTGGCCTGAGCAGCGACAGCTTCGGCGTGGAAAAGCGGGACCTTGATCTGCCTGACCCGGGCAAGTTTTCTCCGCACAGCGCGCCTGTCGCCTACACGGGGAAAATTTCCATCGACGCGCAGGGAAGTTGGAGTCAAGAGGGAATAATCAACTTCATCAGTGCAGGAGTGCAGGACCGGTCCACATCACCAGGATCGTTCTCCACGGGCTCGCCCGCAGGTCCACCTTCAGACTGCTCCAAAATAGTCCAAAATCTTCCCAACATGGAGCACATGTACACAGGGCCACCCCCTTACACCTGTAGCGCCGAGGGCTATCAGGACCCTTCGGTCTACCTGTCGACCACTACATGCCCAATAACATACGCACCTCCGTCATACTCGGCCCCAAAATCAACCATAGACGGGGCGCTTTTCTCCATCATTCCCGATTATGGGGGCTTTTATCAGAACAGCAGCTGCCAAAGGGACAACATGGCAGTTTTTCAGGATATCAAGCCGTTTTCGTGCTCTTTGGAGTCTATTAGAGTCCCACCACCTCTGACTCCCTTGAACACTATAAGGAATTTTACTCTGGCGTGTCCGGTGGACGGCTCAAGGCCGCCGTTAGACGGCACCAACCCGCAGAATGTCCCACTCAGGCCAATACTGCGGCCACGGAAATACCCGAACCGACCGTGCAAGACGCCGGTGCACGAGCGCCCGTATCCGTGTCCGGCCGAGGGATGCGACCGGAGGTTTTCGCGCTCGGATGAGCTCACGCGTCACGTCCGCATCCACACCGGACACAAGCCGTTTCAGTGCCGCATCTGCATGCGCAGCTTCAGCCGGAGCGACCACCTCACGACCCACATCCGCACACACACGGGCGAGAAGCCCTTCTCCTGTGACTTCTGCGGCAGAAAGTTCGCCCGAAGCGACGAGCGAAGGAGGCACACAAAAATCCACCAGAGACATAAGGACAGAAAGCTTTCTGTGGGCCCTCACAGCTCCAGCGCTGGGGGAAACTGATTAGATAGCACATACATGATGTGACCCCTGGGTTCGTCAACCTGGACCTTGTTTGTGTGCACACAAAAAAATACGAAGGCAGCTTATGAATCTTAATGTTGAATGTGGTTTGTTGTAGAAGCTAGTCGTTATCACAGAATATTTCATGTGGTGCATAATGCAGTTGTTCTGAGAAATAGTGTTTACAGTGAGTCTTTTTGTTGACTATTATTGTTACGTGtcttaataaaatgataataaacacAA
>TCONS_00024254
CACTTATTGCTGCGGCACGTATGAAGGGAGCTGATGAGCTCTGACACCGATGCGCGCGTTTATGATGATAACACCGAAGTCAAAACAGCATTGATAACAGCATCAACATTTACAACACAAGCCCTCAGAGCAACTTAATAACAATTCAAGATCGTATATTAACAATATCGAGGATCAAAATGACAGCGACAGCAAGTACCGGGGATAAAATGAGCGCGTCGTTAACGGATTTCATGCGCTGTTTGCCATCTCACGTCTATGGTCTGGATGAGATTCCCCCGTGCGCGCCCACCGGCTTCCCTCATGTGGATGCGGGAGTCTGTTCGGACCACTACAGCGAGGCGTCCGCAGGTGGCCTGAGCAGCGACAGCTTCGGCGTGGAAAAGCGGGACCTTGATCTGCCTGACCCGGGCAAGTTTTCTCCGCACAGCGCGCCTGTCGCCTACACGGGGAAAATTTCCATCGACGCGCAGGGAAGTTGGAGTCAAGAGGGAATAATCAACTTCATCAGTGCAGGAGTGCAGGACCGGTCCACATCACCAGGATCGTTCTCCACGGGCTCGCCCGCAGGTCCACCTTCAGACTGCTCCAAAATAGTCCAAAATCTTCCCAACATGGAGCACATGTACACAGGGCCACCCCCTTACACCTGTAGCGCCGAGGGCTATCAGGACCCTTCGGTCTACCTGTCGACCACTACATGCCCAATAACATACGCACCTCCGTCATACTCGGCCCCAAAATCAACCATAGACGGGGCGCTTTTCTCCATCATTCCCGATTATGGGGGCTTTTATCAGAACAGCAGCTGCCAAAGGGACAACATGGCAGTTTTTCAGGATATCAAGCCGTTTTCGTGCTCTTTGGAGTCTATTAGAGTCCCACCACCTCTGACTCCCTTGAACACTATAAGGAATTTTACTCTGGCGTGTCCGGTGGACGGCTCAAGGCCGCCGTTAGACGGCACCAACCCGCAGAATGTCCCACTCAGGCCAATACTGCGGCCACGGAAATACCCGAACCGACCGTGCAAGACGCCGGTGCACGAGCGCCCGTATCCGTGTCCGGCCGAGGGATGCGACCGGAGGTTTTCGCGCTCGGATGAGCTCACGCGTCACGTCCGCATCCACACCGGACACAAGCCGTTTCAGTGCCGCATCTGCATGCGCAGCTTCAGCCGGAGCGACCACCTCACGACCCACATCCGCACACACACGGGCGAGAAGCCCTTCTCCTGTGACTTCTGCGGCAGAAAGTTCGCCCGAAGCGACGAGCGAAGGAGGCACACAAAAATCCACCAGAGACATAAGGACAGAAAGCTTTCTGTGGGCCCTCACAGCTCCAGCGCTGGGGGAAACTGA

Function

symbol description
egr2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in hindbrain and hindbrain neural keel. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2).

GO:

id name namespace
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030723-6 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in hindbrain and hindbrain neural keel. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2).

Ensembl:

ensembl_id ENSDARG00000044098

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00024252 False 1863 mRNA 0.46 1 43663504 43665366
TCONS_00024253 False 1367 mRNA 0.53 2 43663504 43677471
TCONS_00024254 True 1361 mRNA 0.55 2 43663750 43666166

Neighbor

gene id symbol gene type direction distance location
XLOC_012328 NA coding downstream 14010 43641817 ~ 43649494 (-)
XLOC_012327 rtkn2a coding downstream 40134 43610894 ~ 43623370 (-)
XLOC_012326 zfyve28 coding downstream 68640 43565628 ~ 43594864 (-)
XLOC_012325 nt5c1ab coding downstream 105010 43534115 ~ 43558494 (-)
XLOC_012324 si:dkey-21a6.5 coding downstream 130409 43519290 ~ 43533095 (-)
XLOC_012330 FO704797.1 coding upstream 30928 43708399 ~ 43718395 (-)
XLOC_012331 ahsa1b coding upstream 173045 43850516 ~ 43863700 (-)
XLOC_012332 NA coding upstream 326968 44004439 ~ 44010882 (-)
XLOC_012333 BX511267.1 coding upstream 381340 44058811 ~ 44058927 (-)
XLOC_012334 NA coding upstream 392870 44070341 ~ 44116077 (-)
XLOC_012319 NA non-coding downstream 411584 43250258 ~ 43251920 (-)
XLOC_012310 NA non-coding downstream 1099352 42540854 ~ 42564152 (-)
XLOC_012308 NA non-coding downstream 1390906 42261845 ~ 42272598 (-)
XLOC_012306 NA non-coding downstream 1486516 42167187 ~ 42176988 (-)
XLOC_012336 NA non-coding upstream 677353 44354824 ~ 44409623 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000315_00300283_00302094 EGR2A coding CI01000315 null 300043 ~ 302129 (-)