XLOC_000126 (fgb)



Basic Information


Item Value
gene id XLOC_000126
gene name fgb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 10051763 ~ 10059496 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00000229
CAGGAAGAGCAGCTCTGGATTATCTGCATCTGCCTCACACTTGTGCTGGAACTGAAGTGTGAGTTCTACAAAAATGAAGCTTGTCTTATTACTTTGCCTGTGTGCTGTTGGAGCTCTCGCACAGGATGACTATGATGATTATGGAGAAGGAAAAAAAGAGgCTAAAGAAGTCGTAGACCCCAGGGGTCATCGTCCCGTCAGCAGAGGTCGAGAGACATACTCTCCAGGCCCTGTTTCTCAGCCGCCCATCAGCGGGGGAACCCGATACCGTGGCAGACCAACAGCAGCGCCGGTGGGCAAAGCTGTGCAGGAGAAAGAGGAGCAACCTGAATCAGGCGGATGCAACCATATGTCTGAGAAAATGGGTGTGTTGTGTCCCACAGGTTGTGAGTTGAAGAAAGCCCTCATAAAACAGGAACGTAATGTAAAGCCAACTGTAGAGCAGCTGAAAAGAGCTGTGGACGACTTGACTCAATCCACCAACTCCATCCACGGCTACGTCCTCGATATGACCGCAGAAGTAGCTCAAAGACAAAAAGTCAGCGAGGGCAATGGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCATGCTTATATTAAGGACACGGTGGACGTCACCTTCCCCCAGAACATTAAAGTCCTTCAGGGAGTGCTGGATAAGATCCGTGAGAAGATCCAGCGCTTGGAGAAAGCCATCACTACTCAGAGAGCCAAGTGCCAAGCGCCCTGTAAAGTCACCTGCCCCATTCCTGTTGTGTCCGGCAAGGAGTGCGAAGACATCATCCGCAAAGGAGGAGAGGACTCGCAGATGTACATCATACGGCCTGATCCGCTTGGAACGCCTTACAAGGTCTTCTGCGATCAGACCAGTAAAAATGGAGGTTGGGTGCTCATCCAGAACCGTATGGACGGCAGTGTTGATTTTGGCAGGCGTTGGGACGACTACCGAAGAGGCTTTGGAAACATTGCATTTGATGTGGGCAAAGGCCACTGCCAGACTCCAGGCGAGTACTGGCTGGGCAATGACCGTATTAGTCAACTTTCAAAGATGGGTGCCACTGAGCTTCTGGTGGAGATGGAGGACTGGTCCGGCTCAAAAGTCTATGCTCAGTATGAGCAGTTCAGCATGCAGGGCGAAGCCTCCAACTACATCCTAGGAGTCGGACGGTACTCAGGAACGGCTGGAAATACATTCCTGGAAGGCGCAACAGAGCTGTTTGGAGAGAATCGTACCATGACCATCCACAACGGCATGATGTTCAGCACATACGACAGGGATAATGACAAATGGATTCCTGGAGATCCTTCTAAACAGTGCTCTAAAGAAGATGGCGGTGGATGGTGGTACAACAGATGCCACTCTTGTAATCCTAACGGGCGATACTATTGGGGAGGAGCTTATACTAAATACATGGCCAAGCACGGGACAGATGACGGCATCGTGTGGATGAACTGGAAGGGCTCGTGGTATTCGCTCAAAACGATCAGCATGAAGATTAGGCCGTACttcaaacagaaataaaacttcATGTGAAATGAAATGCGTGTCGTTTCCTGCAGCATCTCATTTCATataggctattttttttaaataaagcggAGGATAGTAAAGCCTGCATAAAAGAGTGTGAATACATTGGAAAAGTGCATTGGATACATTGTGTTATTGGACATGTTAAAGTACTGTATGTAAAGGCAAAATGATGGAAATGAGATGGAAACAGTTCTCCTGGTTCTCATTAAAGCTGaccaacaaacaacaaaactttGTCTATTGTATTTATGAACGTTTTGTAATGTTTTAGAAAATAAACATgcttaaaaca
>TCONS_00000230
GCTCTGGATTATCTGCATCTGCCTCACACTTGTGCTGGAACTGAAGTGTGAGTTCTACAAAAATGAAGCTTGTCTTATTACTTTGCCTGTGTGCTGTTGGAGCTCTCGCACAGGATGACTATGATGATTATGGAGAAGGAAAAAAAGAGgCTAAAGAAGTCGTAGACCCCAGGGGTCATCGTCCCGTCAGCAGAGGTCGAGAGACATACTCTCCAGGCCCTGTTTCTCAGCCGCCCATCAGCGGGGGAACCCGATACCGTGGCAGACCAACAGCAGCGCCGGTGGGCAAAGCTGTGCAGGAGAAAGAGGAGCAACCTGAATCAGGCGGATGCAACCATATGTCTGAGAAAATGGGTGTGTTGTGTCCCACAGGTTGTGAGTTGAAGAAAGCCCTCATAAAACAGGAACGTAATGTAAAGCCAACTGTAGAGCAGCTGAAAAGAGCTGTGGACGACTTGACTCAATCCACCAACTCCATCCACGGCTACGTCCTCGATATGACCGCAGAAGTAGCTCAAAGACAAAAAGTCAGCGAGGGTAACTACacttcagaaagttttgtttatatgatatttgttttaaagtaatagttgtctaatgacttgcctaattatgaCTGATTACTATAGTATCTTttcaaatatctagtaaaaaattcTGTactgactgtcatcatggccgagaaaaaagaaatgagttataggaaatgagttattaaagctattatgtttaaaaaggacttttaaaaagaatgaaaagttcacaggaggtctaataatttcATTGCATGTcgagtaaattaat
>TCONS_00000231
ATCTGCATCTGCCTCACACTTGTGCTGGAACTGAAGTGTGAGTTCTACAAAAATGAAGCTTGTCTTATTACTTTGCCTGTGTGCTGTTGGAGCTCTCGCACAGGATGACTATGATGATTATGGAGAAGGAAAAAAAGAGgCTAAAGAAGTCGTAGACCCCAGGGGTCATCGTCCCGTCAGCAGAGGTCGAGAGACATACTCTCCAGGCCCTGTTTCTCAGCCGCCCATCAGCGGGGGAACCCGATACCGTGGCAGACCAACAGCAGCGCCGGTGGGCAAAGCTGTGCAGGAGAAAGAGGAGCAACCTGAATCAGGCGGATGCAACCATATGTCTGAGAAAATGGGTGTGTTGTGTCCCACAGGTTGTGAGTTGAAGAAAGCCCTCATAAAACAGGAACGTAATGTAAAGCCAACTGTAGAGCAGCTGAAAAGAGCTGTGGACGACTTGACTCAATCCACCAACTCCATCCACGGCTACGTCCTCGATATGACCGCAGAAGTAGCTCAAAGACAAAAAGTCAGCGAGGGCAATGGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCATGCTTATATTAAGGACACGGTGGACGGCGAAGCCTCCAACTACATCCTAGGAGTCGGACGGTACTCAGGAACGGCTGGAAATACATTCCTGGAAGGCGCAACAGAGCTGTTTGGAGAGAATCGTACCATGACCATCCACAACGGCATGATGTTCAGCACATACGACAGGGATAATGACAAATGG
>TCONS_00000232
aatagatataaaaagTGAATGGAGATGAGATGAGAATAAAAAGAagacattatatttaaaaatatatatagtatacgGTGGTGTGTTGTGTCCCACAGGTTGTGAGTTGAAGAAAGCCCTCATAAAACAGGAACGTAATGTAAAGCCAACTGTAGAGCAGCTGAAAAGAGCTGTGGACGACTTGACTCAATCCACCAACTCCATCCACGGCTACGTCCTCGATATGACCGCAGAAGTAGCTCAAAGACAAAAAGTCAGCGAGGGCAATGGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCATGCTTATATTAAGGACACGGTGGACGTCACCTTCCCCCAGAACATTAAAGTCCTTCAGGGAGTGCTGGATAAGATCCGTGAGAAGATCCAGCGCTTGGAGAAAGCCATCACTACTCAGAGAGCCAAGTGCCAAGCGCCCTGTAAAGTCACCTGCCCCATTCCTGTTGTGTCCGGCAAGGAGTGCGAAGACATCATCCGCAAAGGAGGAGAGGACTCGCAGATGTACATCATACGGCCTGATCCGCTTGGAACGCCTTACAAGGTCTTCTGCGATCAGACCAGTAAAAATGGAGGTTGGGTGCTCATCCAGAACCGTATGGACGGCAGTGTTGATTTTGGCAGGCGTTGGGACGACTACCGAAGAGGCTTTGGAAACATTGCATTTGATGTGGGCAAAGGCCACTGCCAGACTCCAGGCGAGTACTGGCTGGGCAATGACCGTATTAGTCAACTT
>TCONS_00000233
AGAGCTGTGGACGACTTGACTCAATCCACCAACTCCATCCACGGCTACGTCCTCGATATGACCGCAGAAGTAGCTCAAAGACAAAAAGTCAGCGAGGGCAATGGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCATGCTTATATTAAGGACACGGTGGACGTCACCTTCCCCCAGAACATTAAAGTCCTTCAGGGAGTGCTGGATAAGATCCGTGAGAAGATCCAGCGCTTGGAGAAAGCCATCACTACTCAGAGAGCCAAGTGCCAAGCGCCCTGTAAAGTCACCTGCCCCATTCCTGTTGTGTCCGGCAAGGAGTGCGAAGACATCATCCGCAAAGGAGGAGAGGACTCGCAGATGTACATCATACGGCCTGATCCGCTTGGAACGCCTTACAAGGTCTTCTGCGATCAGACCAGTAAAAATGGAGGTATGGCAACTTTGGCCTTGTCTACtctattacattttacagttacCCTAGACACAGCTTtttctgtaaacacacac

Function


symbol description
fgb Predicted to enable signaling receptor binding activity. Acts upstream of or within blood coagulation, fibrin clot formation. Predicted to be located in extracellular region. Predicted to be part of fibrinogen complex. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal disease. Orthologous to human FGB (fibrinogen beta chain).

GO:

id name namespace
GO:0070527 platelet aggregation biological_process
GO:0072378 blood coagulation, fibrin clot formation biological_process
GO:0030168 platelet activation biological_process
GO:0007596 blood coagulation biological_process
GO:0051258 protein polymerization biological_process
GO:0007155 cell adhesion biological_process
GO:0007160 cell-matrix adhesion biological_process
GO:0062023 collagen-containing extracellular matrix cellular_component
GO:0005577 fibrinogen complex cellular_component
GO:0005615 extracellular space cellular_component
GO:0005102 signaling receptor binding molecular_function

KEGG:

id description
ko04610 Complement and coagulation cascades
ko04611 Platelet activation
ko04613 Neutrophil extracellular trap formation
ko05171 Coronavirus disease - COVID-19
ko04147 Exosome
ko00536 Glycosaminoglycan binding proteins

ZFIN:

id description
ZDB-GENE-030131-9261 Predicted to enable signaling receptor binding activity. Acts upstream of or within blood coagulation, fibrin clot formation. Predicted to be located in extracellular region. Predicted to be part of fibrinogen complex. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal disease. Orthologous to human FGB (fibrinogen beta chain).

Ensembl:

ensembl_id ENSDARG00000008969

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00000229 False 1835 mRNA 0.48 8 10051763 10059496
TCONS_00000230 False 804 processed_transcript 0.43 4 10051774 10054771
TCONS_00000231 False 760 processed_transcript 0.50 6 10051784 10058057
TCONS_00000232 False 766 processed_transcript 0.48 5 10054019 10057808
TCONS_00000233 True 516 lncRNA 0.49 2 10054408 10055303

Neighbor


gene id symbol gene type direction distance location
XLOC_000125 trim2b coding upstream 18650 10003193 ~ 10033113 (+)
XLOC_000124 si:dkeyp-75b4.10 coding upstream 51387 9994811 ~ 10000376 (+)
XLOC_000123 si:dkeyp-75b4.8 coding upstream 69649 9966384 ~ 9982114 (+)
XLOC_000122 pdia2 coding upstream 85568 9954489 ~ 9966195 (+)
XLOC_000121 NA coding upstream 99890 9946664 ~ 9951873 (+)
XLOC_000127 si:ch73-132f6.5 coding downstream 14847 10074343 ~ 10124192 (+)
XLOC_000128 rbm46 coding downstream 67667 10127163 ~ 10137776 (+)
XLOC_000129 npy2rl coding downstream 162072 10221568 ~ 10235337 (+)
XLOC_000130 eif3f coding downstream 237531 10297027 ~ 10304044 (+)
XLOC_000131 zgc:77880 coding downstream 246115 10305611 ~ 10315206 (+)
XLOC_000120 NA non-coding upstream 137133 9886955 ~ 9914630 (+)
XLOC_000116 BX323038.1 non-coding upstream 766412 9277846 ~ 9285351 (+)
XLOC_000111 NA non-coding upstream 919273 9129386 ~ 9132490 (+)
XLOC_000106 NA non-coding upstream 1075341 8967479 ~ 8976422 (+)
XLOC_000133 AL935188.1 non-coding downstream 304224 10363720 ~ 10363851 (+)
XLOC_000135 NA non-coding downstream 402548 10462044 ~ 10462882 (+)
XLOC_000136 NA non-coding downstream 558028 10617524 ~ 10617930 (+)
XLOC_000137 NA non-coding downstream 585768 10645264 ~ 10668028 (+)
XLOC_000138 NA non-coding downstream 585868 10645364 ~ 10680841 (+)

Expression



Co-expression Network