XLOC_012850 (mafa)



Basic Information


Item Value
gene id XLOC_012850
gene name mafa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 29402623 ~ 29413756 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00025638
CGAGTTTAAAAACACTCTGAGCTCGATCTGTGTCAGCAGCATCTAGCGCACATCTCTCACGTTACACTTACCCGTTTGACCACGATGATGTCTGCACTCGAGGAGTCACCAAAGTGTTAAATGTTTGAAATACAAGGCCGCCGAAATCCACATGTAAAAAGAGGAGAAAGAGATCCGATGCATCTGTGCAATAGACTGTGCCACGGATAATCTGGAGTTTAGGAGCGCACTGAAAACTCCCGTGCAGCCTCTTgtctgtttttttgtattttttttattttcctgctTAGAGTAAAGCATTTTAAACATCATCAAGCTGGCTCACTCTCTCCCGACCCAGCCCGCTTTGACAGCTCCTCTTCACCCGCTCTGGAGGACGGTCAGCAGCAAGAGGATGGCATCAGAGCTGGCACTGAGCAGCTCCGACCTGCCCACCAGTCCCCTGGCCATGGAATATGTTAATGACTTCGATCTGATGAAGTTTGAGGTGAAGAAAGAGCCACTGGAGCCCGATCGCAGCATCAGCCAGTGCAGCCGCCTGATCGCCGGGGGCTCCCTGTCTTCCACCCCGATGAGCACGCCCTGCAGCTCGGTTCCCCCTTCCCCAAGCTTTTCAGCGCCCAGCCCTGGCTCCGGGAACGAGCAGAAGGCGCACTTGGAGGATTTCTACTGGATGACCGGTTATCAGCAGCAGCTCAACCCGGAGGCGTTGGGCTTCAGTCCCGAGGACGCAGTTGAAGCGCTGATCAACAGCACACACCAGCTCCAGAGCTACGACGGCTATGCTAGAGGGCAGCAGTTTAGTAACACGGCCGGGACGGGAGGCGCCATGGCCGGGGAGGAGATGGGATCCGCCGCCGCGGTGGTCTCCGCAGTCATTGCCGCCGCTGCAGCGCAGAACGGGGCAcctcatcaccaccaccaccatcaccaccacgGCCACCACCAGCAGCACCAAACTCCCGGCGTCCCGTCCAGCACCAACTCCCCTGTCGCCCATCACCAGCACAGCCACCTGGACGATCGCTTCTCGGACGATCAGCTCGTTACCATGTCCGTGCGGGAGCTCAACCGGCAGCTGCGCGGCGTCAGCAAAGAGGAGGTGATCCGGCTCAAACAGAAGAGAAGAACCCTCAAAAACAGAGGCTATGCCCAGTCGTGTCGCTACAAGAGGGTCCAGCAGAGGCACATACTGGAGGGCGAGAAGACCCAGCTCATTCAGCAGGTGGACCACCTCAAACAAGAGATCTCCAGACTGGTGCGCGAGAGAGACGCGTACAAAGAAAAGTACGAGAAGCTGGTGAACAGCGGCTTCCGAGAAAACTCATCGAGCAGCGACAACAACCCCTCGTCCCCGGAGTTTTTCATGTGAGTTCcataaaaaaagcataaaaagaaaacaagtaaagttttcaaaacttttttttctgctttgggGGGTTGTTAGATCAAATCTGACGACTTTTTTATCGCTTTTATAAAGAACTGAGTTCAGTTCTTGCTGAGTTTGGGGGGCTTGTTGTGcaaccaaacatttttttctttataaaaattAGTATTATTCTCTAAATGAGTTAATATTCTGACGTGTATGCACATACACTCATGATATTGAACTTCATtcgcattttttgttttttttttgtttttgccaaaTGACAAagtttgctatttttattttttatacatatatttttgctCTTTTACCAAAGTCGATGGATTTTGCCCCATTATCATCTCATTCTGCTTGCTGTTTTGTGACTTTTTATGAGAATCTAAAGACATTGTTGTTATATAAAGAGACATATCGTTGAAGTGCCTGCATGCTGGACATGTAtggtctttttttttgtctttctttatTCCCCTTTCATTTTTTATGCGCTTAAAAATGAACTTCTACTTGGGAAAAGAACTTCTGCTCAGCATGGCATTCATACATTTCTTTAATTTCCCCATCACTTTTTTGGAATACGGACTAAAAAAGTGAAAGGAGCATCATGTCATCATCCTCCTCATGAAAAAGTTGATCCATATACTTTCCATACAGTTAATTCTCTGTTGAGAGCCAACTGGAAGCAGGGAGAGAACAAGGACCTGGTTTCTAAAAGGAATTCTCCCTCTGGGACTTGAACAGTGTTGTTGCTAAAAGCGGTTTGTGTATTTAATGTCAAACCTTTGCATTTTGATAACTCTGGAATgaactactttttttttatcatataaaaCAGTCAAAGGTAGCCCATGCCACAGGTTGACACAGAGAAGAAGGGGTGACTTAGAGTTTAGATGTTCAGTTTGTTAAAAGTTTGGGAAGGCTCCAAGTTTGCATACAGCTGGATTTTTATCATGTGTAACTTGAGCTTTTTGGAGCATGTACTTGCAATGAAAACAGCAGTTTGACAGTTGTAGTTCCTGTTGTAGCCtgccatttactgcattttaaaaccAAAGTATTAAAGTAGAATTTCAAGTCAACCTGGAAAATCATGCattcaaaagaagaagaaaaacataGTCTGATATGAAATCTGACCTATCTGGAATGAGTTGCACTAAATGTAGCTTGTAGCAAATTATATATCACATATTGGAATCTATCTAGAACGCTAATTTAAAAGGCACCCGTCATGGCTTTGCTTAAAACTAAAGGACTTAATCTtatttagatttatatatattgtcAAGCAGGACTcgattctttctctctctctttctttctttcatacttgttaataaaatcattatttacaTGGCAATAATGTAGTAATCAATATTAAAATGTCTGGACATTGTTTTATGGTCAGGGATTGATACCCTGCATGTATAAATTCAGGACATACCGTTCATCAATAAATTCTTAAAActatgttaattattattattattattatttgtttgtttcatatATATTTTGCTGTGCAAAATTATTTTATCCACTAACTATATGTGATGTTCATATATGCTTATTTTCATTTCATACATATATGATATGCAATAAAATGCAATTTGGGCCACTTAAA
>TCONS_00025639
ATGGCATCAGAGCTGGCACTGAGCAGCTCCGACCTGCCCACCAGTCCCCTGGCCATGGAATATGTTAATGACTTCGATCTGATGAAGTTTGAGGTGAAGAAAGAGCCACTGGAGCCCGATCGCAGCATCAGCCAGTGCAGCCGCCTGATCGCCGGGGGCTCCCTGTCTTCCACCCCGATGAGCACGCCCTGCAGCTCGGTTCCCCCTTCCCCAAGCTTTTCAGCGCCCAGCCCTGGCTCCGGGAACGAGCAGAAGGCGCACTTGGAGGATTTCTACTGGATGACCGGTTATCAGCAGCAGCTCAACCCGGAGGCGTTGGGCTTCAGTCCCGAGGACGCAGTTGAAGCGCTGATCAACAGCACACACCAGCTCCAGAGCTACGACGGCTATGCTAGAGGGCAGCAGTTTAGTAACACGGCCGGGACGGGAGGCGCCATGGCCGGGGAGGAGATGGGATCCGCCGCCGCGGTGGTCTCCGCAGTCATTGCCGCCGCTGCAGCGCAGAACGGGGCAcctcatcaccaccaccaccatcaccaccacgGCCACCACCAGCAGCACCAAACTCCCGGCGTCCCGTCCAGCACCAACTCCCCTGTCGCCCATCACCAGCACAGCCACCTGGACGATCGCTTCTCGGACGATCAGCTCGTTACCATGTCCGTGCGGGAGCTCAACCGGCAGCTGCGCGGCGTCAGCAAAGAGGAGGTGATCCGGCTCAAACAGAAGAGAAGAACCCTCAAAAACAGAGGCTATGCCCAGTCGTGTCGCTACAAGAGGGTCCAGCAGAGGCACATACTGGAGGGCGAGAAGACCCAGCTCATTCAGCAGGTGGACCACCTCAAACAAGAGATCTCCAGACTGGTGCGCGAGAGAGACGCGTACAAAGAAAAGTACGAGAAGCTGGTGAACAGCGGCTTCCGAGAAAACTCATCGAGCAGCGACAACAACCCCTCGTCCCCGGAGTTTTTCATGTCTTCCAGAAAGTTCCTTCATCTGTGACTGTGAGCTCCTTGAGTATGGCCTTGATGAGTGAG

Function


symbol description
mafa Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in pronephric mesoderm; pronephric proximal convoluted tubule; pronephric proximal straight tubule; and solid lens vesicle. Human ortholog(s) of this gene implicated in Ayme-Gripp syndrome; cataract; and cataract 21 multiple types. Orthologous to human MAF (MAF bZIP transcription factor).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function

KEGG:

id description
ko04930 Type II diabetes mellitus
ko04950 Maturity onset diabetes of the young
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-010605-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in pronephric mesoderm; pronephric proximal convoluted tubule; pronephric proximal straight tubule; and solid lens vesicle. Human ortholog(s) of this gene implicated in Ayme-Gripp syndrome; cataract; and cataract 21 multiple types. Orthologous to human MAF (MAF bZIP transcription factor).

Ensembl:

ensembl_id ENSDARG00000015890

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00025638 False 3023 mRNA 0.43 1 29402623 29405645
TCONS_00025639 True 1037 mRNA 0.60 2 29403017 29413756

Neighbor


gene id symbol gene type direction distance location
XLOC_012848 ppfibp2a coding upstream 208915 29145681 ~ 29193708 (+)
XLOC_012849 CT025546.2 coding upstream 227415 29175093 ~ 29175208 (+)
XLOC_012847 syt9a coding upstream 341781 28988373 ~ 29060842 (+)
XLOC_012846 spon1a coding upstream 522432 28564640 ~ 28880191 (+)
XLOC_012845 CR769777.2 coding upstream 1098306 28303891 ~ 28304317 (+)
XLOC_012851 cenpn coding downstream 485199 29898955 ~ 29906010 (+)
XLOC_012852 atmin coding downstream 536477 29950233 ~ 29955391 (+)
XLOC_012853 si:ch211-220f16.1 coding downstream 614379 30028135 ~ 30030949 (+)
XLOC_012854 NA coding downstream 716015 30129771 ~ 30131831 (+)
XLOC_012855 gse1 coding downstream 743278 30157034 ~ 30480827 (+)
XLOC_012841 BX649600.1 non-coding upstream 1665783 27736724 ~ 27736840 (+)
XLOC_012835 BX640463.2 non-coding upstream 2206297 27196210 ~ 27196326 (+)
XLOC_012832 NA non-coding upstream 2404034 26997576 ~ 26998589 (+)
XLOC_012863 NA non-coding downstream 1659487 31073243 ~ 31075619 (+)
XLOC_012865 NA non-coding downstream 1867094 31280850 ~ 31459487 (+)
XLOC_012866 NA non-coding downstream 2105822 31519578 ~ 31521691 (+)
XLOC_012868 BX908763.1 non-coding downstream 2431748 31845504 ~ 31846556 (+)

Expression



Co-expression Network