XLOC_012979 (bcl2l10)



Basic Information


Item Value
gene id XLOC_012979
gene name bcl2l10
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 39106722 ~ 39119005 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00025844
GAAGATCGTCTCCTATGAGATCTCACCGCTGTTTGCGCAACTGTCGTGGAGAGCGCAGTCTGACATCGCTGGGAGGAAAATGTCCTGTTGGTTGAGGGAACAGACTCTGTTGCTGGCGGAGGACTACATCAGCTTCTGCAGTGGGATCCAACAGACGCCTCCCAGCGAGTCGGCGGAGGCCATGAGGTACCTGGCCAAAGAAATGGAGCAGCAGCACAGAACCAAATTCCGATCCCTTTCCCAGGAGTTCCTGGACACCTGCGGAGCAGATCCCAGCAAATGTCTGCAGAGCGTCATGAGAGAACTGGTGGGAGATGGGAAAATGAACTGGGGAAGGGTGGTCTCTATCTTCACATTCACTGGAGTGCTGGCCAGTGAACTACTGTCCAGGGGAGAGAATTCGGAGGGTTCCCGAAGATTGGCCGAGACTATAGCAGACTACCTAGGAGGAGAAAAACAGGACTGGCTGGTGGAAAACGGAGGCTGGgAGGGTTTTTGCAGGTTTTTCCACAACGCAAGACAACTGAACCAGGAGTCCTCCATGAAAACAGCACTGTTTGCAGCAGCAGGAGTGGGTTTAGCTGGTCTAACCTTCCTCTTAGTACGCTGATGATTTTAGAATGCTCTTGCTCAATTTCACATTGACACACACAACAACACCTGATCTCTGTATTCTGTCATATGGCGAAGTCAAAACAGTTCTTATCGAGAAACCGGTCTTTTTGCACACTGTTTTTTCCCCACGCCTGTAATTACAGCAAACAGTCATTCATGTTGATTGTACACTATTCACATGGCCTTCAGGAGAGAGAAAGACGGAAGATTGAATCCTTTGCATATCTAACATGgtgcttttttatttcataattaccTTTATCACTCGTTTCTGTGTACATCCGGCTAGTTTAGATagtatttacagtttattttgtgAAAAAACGATATGAAACCAGTTTGTTTGTAATGTTTCTTTCAGTCTGAAAACAAGACGCTTGAGCGAACGCAGTTGTGTCTGAAAACATTCTAAGAGACGATATATTTTGTAATGAAAGATCTTTTTTTGTTGGACCACCTTTTGCTGTGCTTTAGTGGTTTCCCGCCTTTTCGGATGTCGCCTGTTTCATCCTGGAAATCGATTCGTTTTTAAGGTGCTAGCTTGTTTTGGTTCCAAGCGATTTCTGTGATACTCTGCCCACTTGTAAGTGACTCAGTTTACgctgtaaatttatttatttacttctaaAGAACAAATTATTACTATTTAGGCAATTCCCAACAATCaacaaaacattatatttttgcattgttttatttattaacttctttcttaataaaataattttactgtG

Function


symbol description
bcl2l10 Predicted to enable protein heterodimerization activity and protein homodimerization activity. Acts upstream of or within several processes, including epiboly; regulation of release of sequestered calcium ion into cytosol; and somitogenesis. Located in mitochondrion. Is expressed in several structures, including digestive system; margin; mesoderm; nervous system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10).

GO:

id name namespace
GO:0042981 regulation of apoptotic process biological_process
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway biological_process
GO:0001756 somitogenesis biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0051279 regulation of release of sequestered calcium ion into cytosol biological_process
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand biological_process
GO:0007369 gastrulation biological_process
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage biological_process
GO:0019722 calcium-mediated signaling biological_process
GO:0090504 epiboly biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005741 mitochondrial outer membrane cellular_component
GO:0005515 protein binding molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0046982 protein heterodimerization activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030825-2 Predicted to enable protein heterodimerization activity and protein homodimerization activity. Acts upstream of or within several processes, including epiboly; regulation of release of sequestered calcium ion into cytosol; and somitogenesis. Located in mitochondrion. Is expressed in several structures, including digestive system; margin; mesoderm; nervous system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10).

Ensembl:

ensembl_id ENSDARG00000026766

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00025844 True 1349 mRNA 0.43 3 39106722 39119005

Neighbor


gene id symbol gene type direction distance location
XLOC_012978 gnb5b coding upstream 1203 39067575 ~ 39105519 (+)
XLOC_012977 zgc:171509 coding upstream 41607 39060687 ~ 39065115 (+)
XLOC_012976 myo5aa coding upstream 64521 38900092 ~ 39042201 (+)
XLOC_012975 arpp19a coding upstream 209058 38885309 ~ 38897664 (+)
XLOC_012974 fam214a coding upstream 249110 38774584 ~ 38857612 (+)
XLOC_012980 NA coding downstream 46358 39165363 ~ 39173192 (+)
XLOC_012981 tmod2 coding downstream 208005 39327010 ~ 39382869 (+)
XLOC_012982 lysmd2 coding downstream 297352 39416357 ~ 39430956 (+)
XLOC_012983 acadl coding downstream 368481 39487486 ~ 39505847 (+)
XLOC_012984 NA coding downstream 502460 39621465 ~ 39632025 (+)
XLOC_012972 NA non-coding upstream 352030 38748613 ~ 38754692 (+)
XLOC_012971 NA non-coding upstream 587919 38403325 ~ 38518803 (+)
XLOC_012967 CR381582.2 non-coding upstream 1088704 38017901 ~ 38018018 (+)
XLOC_012966 CR381582.1 non-coding upstream 1143825 37962778 ~ 37962897 (+)
XLOC_012965 AL627088.2 non-coding upstream 1648160 37458446 ~ 37458562 (+)
XLOC_012986 FO905036.1 non-coding downstream 617384 39736389 ~ 39736503 (+)
XLOC_012988 BX005280.1 non-coding downstream 904767 40023772 ~ 40023888 (+)
XLOC_012992 BX323575.2 non-coding downstream 1347785 40466790 ~ 40466904 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000028_06930121_06933901 BCL2L10 coding CI01000028 null 6929823 ~ 6934781 (-)
bowfin (Amia calva) AMCG00007517 NA coding CM030123.1 CM030123.1 21180850 ~ 21186026 (+)