CI01000321_00785868_00790038 (CTNNB1, CTNNB2)


Basic Information

Item Value
gene id CI01000321_00785868_00790038
gene name CTNNB1, CTNNB2
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000321
NCBI id null
chromosome length 5206101
location 785868 ~ 791009 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000321_00785868_00790038.mRNA
CTGACCTTATGGAGCTTGATATGGCCATGGAGCAGGATCGTAAAGCTGCTGTGAGTCACTGGCAGCAGCAGTCTTACCTGGATTCAGGTATTCACTCTGGGGCCACCACCACAGCGCCATCTCTGTCAGGCAAAGGCAACCCTGAAGAGGAGGATCTGGACAACCAGGTGCTGTATGAGTGGGAGCAGGGCTTCAACCAGCCCTTTACACCTGAGCAGGTGGCAGACCTGGATGGGCAGTATGCCATGACCCGTGCCCAGCGTGTCCGTGCTGCCATGTTTCCTGAGACTCTTGATGAGGGCATGCAGATCACTTCTACCCAGTTTGACTCTGCCCACCCTACCAATGTGCAGAGGCTGGCTGAGCCTTCACAAATGCTCAAACATGCTGTTGTCAATCTCATTAACTACCAGGATGATGCTGAGTTGGCCACCAGAGCCATTCCTGAGCTCACCAAACTTCTCAATGATGAGGACCAGGTGGTGGTGAACAAAGCTGCAGTGATGGTGCACCAGCTCTCCAAGAAAGAGGCCTCTCGCCACGCCATTATGCGCTCCCCCCAGATGGTGTCAGCCATCGTGAGGACCATGCAGAACACAAGTGATGTGGAGACTGCCCGTTGCACTGCCGGCACCTTGCACAACCTGTCCCACCACAGAGAGGGCCTTCTAGCCATCTTTAAGTCAGGAGGAATCCCTGCCCTCGTCAAAATGCTGGGGTCCCCCGTGGACAGTGTGCTGTTCTATGCCATCACAACCCTGCACAACCTCCTGCTCCATCAGGAAGGTGCTAAAATGGCTGTCCGTCTAGCTGGAGGACTTCAGAAGATGGTGGCCCTGCTCAACAAAACCAACGTCAAATTCCTCGCCATCACCACAGACTGCTTACAGATCCTGGCATATGGCAACCAGGAGAGCAAGGCAAGTGGTATGCAGGCTCTCGGCCTTCACTTGACAGATCCCAGCCAGCGTCTGGTTCAAAACTGCCTCTGGACCCTCAGAAACTTGTCAGATGCTGCCACAAAGCAGGAAGGGATGGAAGGACTTCTTGGCACTCTAGTTCAGCTTCTTGCTTCTGATGACATTAATGTGGTCACCTGTGCTGCCGGCATACTATCCAACCTCACATGTAACAACTACAAGAACAAGATGATGGTTTGCCAAGTTGGTGGAATCGAGGCCCTAGTCCGCACTGTTCTCAGAGCTGGTGACAGAGAGGACATCACCGAGCCTGCCGTATGCGCGCTACGCCATCTTACCTCCAGACACCAAGATGCTGAGATGGCCCAGAATGCAGTTCGTCTTCACTATGGCCTGCCTGTTGTGGTCAAACTGCTGCACCCACCCTCACACTGGCCGTTAATTAAGGCCACAGTCGGTCTGATCCGTAATCTGGCACTATGCCCTGCCAATCATGCGCCACTCCGTGAGCAGGGTGCAATTCCTCGATTGGTCCAACTGCTGGTGAGGGCACACCAGGACACCCAGAGACGCACTTCAATGGGTGGTACACAGCAACAGTTTGTGGAGGGAGTTCGTATGGAGGAGATCGTGGAAGGCTGCACTGGAGCACTTCACATCCTGGCCAGAGATGTGCACAACAGAATCGTTATCAGGGGGCTCAACACCATCCCCTTATTTGTACAACTGCTCTATTCCCCCATTGAGAATATCCAGCGGGTGGCAGCAGGAGTGTTGTGCGAGCTGGCTCAGGATAAGGAGGCTGCAGAGGCCATTGAGGCAGAAGGAGCCACTGCTCCTCTCACAGAGCTGTTACACTCCAGAAATGAGGGAGTGGCCACATATGCTGCAGCAGTGCTGTTCCGCATGTCCGAGGATAAGCCTCAGGACTACAAGAAACGTCTTTCTGTGGAACTTACCAGCTCTCTTTTCAGAACAGAGCCCATGTCCTGGAATGAGGGAGAGCCTCTTGGATACAGAACAGATGACCCCAGCTATCGTTCTTTCCACTCTGGCTACGGTCAGGATGGTCTTGGTATGGATGGCATGCTGGAGCATGAGATGGGAGGACACCATCCTGGAGCAGAGTACCCAGTAGAGGGACTGCCCGACTTGGGCCATGCTCAGGACCTGATGGATGGCCTGCCCCCTACAGACTCCAATCAGCTGGCGTGGTTTGACACGGACCTTTAAACACTCATGGTCTAAAAGCTCTGAAGGTAAGATGACTTTCAAAAACTCTGCTTGGGAAGTGCATTCTACTTGGGTTTTAATCTAAACATTAATGTGCTTCTCTCTCTCTCTGCAGCTGTATGTTGAATGAATCTGTATTGTGATTTGAAGAGTCGTGGAAGGTTTGCCAGAGGGTGGGCTAGTGTTTCAGAAAGTGCCTGACACACAACACTTGTCGCAGACGAAGGGGAGATGTCTAACGGAAAATGGTGGATGTCAGTCTCCTTAATTGCTACGACCCCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCCCTGGATGGAAAAATGCAAGTACAGAAGGATTGTGACGTGGATACTGACAAGTGCACATGAAAAGGATCTTTTAAGATGGAACTCTTTTAGCTTTTTTTTTTCTTTTTTTTTTTTTTTCCTTAAATTAACCTTTTCATGGTACTGACCCTAGCTTGGTTTTTAAACCTGGCCCTTTTTTCTGCCATAAACTTGTATTCAATATTTTCTTTTTCTTTTTTTCCCCTTTTCTTTTTTTTTAAATGTCTTCTATAGTGTTAAGTTGTAGTGGACTTGCCTCATTGATTTCTGGATCTTTATCACTCACGTGCTAGTGAACAACACTAATCTCAGTTCCTATGTAATCTGACTGAAAGTGTAACAATGTGTAGCTTTTTATATGATCAGTTAAAATGGTGGTTGTTGGGAGTTAAAACTATATGCATTCTTACAAAATGCTTAATGTTAAGCAAGGAGAAGCAGTTTTCAATGTCACTATTGTTCCAAAAAGGGTGTGGGTGCTGCAAGGGTGGGTGGGTTGTAGATGTGGGTTTATGAGGTATACACAGAGACAGAAATCTTTTCTATGCTATCTGGAGGTAGTCTCTATTGAAGCAACGTCATTGTTTGTTAGCCCGTTCGGCTTTTTTTGGGAACATGGATAATGACATGGCTAATCA

Function

symbol description
ctnnb1 Enables cadherin binding activity. Involved in positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification. Acts upstream of or within several processes, including determination of dorsal/ventral asymmetry; ectoderm development; and glomerular filtration. Located in several cellular components, including intercalated disc; microvillus; and zonula adherens. Part of catenin complex. Is expressed in several structures, including EVL; adaxial cell; brain; germ ring; and gonad. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Orthologous to human CTNNB1 (catenin beta 1).
ctnnb2 Predicted to enable several functions, including alpha-catenin binding activity; cadherin binding activity; and transcription coactivator activity. Involved in canonical Wnt signaling pathway. Acts upstream of or within convergent extension; determination of dorsal identity; and dorsal/ventral axis specification. Located in nucleus. Is expressed in corneal endothelium; interneuromast cell; neuromast; and secondary posterior lateral line primordium. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); nephroblastoma; and pilomatrixoma. Orthologous to human CTNNB1 (catenin beta 1).

GO:

id name namespace
GO:2001234 negative regulation of apoptotic signaling pathway biological_process

KEGG:

id description
K02105 CTNNB1; catenin beta 1

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000321_00785868_00790038.mRNA True 3124 mRNA 0.49 12 785868 791009

Neighbor

gene id symbol gene type direction distance location
CI01000321_00697882_00700283 CCK coding upstream 85555 697066 ~ 700313 (+)
CI01000321_00649226_00658653 NA coding upstream 126918 649226 ~ 658950 (+)
CI01000321_00559268_00567811 NA coding upstream 217730 559268 ~ 568138 (+)
CI01000321_00549095_00550611 NA coding upstream 235220 549095 ~ 550648 (+)
CI01000321_00511077_00516356 NA coding upstream 269512 510554 ~ 516356 (+)
CI01000321_00815160_00819665 NA coding downstream 24151 815160 ~ 819749 (+)
CI01000321_00844476_00879488 CPNE4A, CPNE4B, CPNE4 coding downstream 53285 844294 ~ 879693 (+)
CI01000321_00887320_00899893 MRPL3 coding downstream 96311 887320 ~ 900122 (+)
CI01000321_00909867_00919491 NA coding downstream 118429 909438 ~ 920478 (+)
CI01000321_00981761_00983302 NA coding downstream 190492 981501 ~ 983955 (+)
G456868 NA non-coding upstream 49387 735187 ~ 736481 (+)
G456867 NA non-coding upstream 67654 716699 ~ 718214 (+)
G456842 NA non-coding upstream 151949 632724 ~ 633919 (+)
G456806 NA non-coding upstream 240757 544844 ~ 545111 (+)
G456805 NA non-coding upstream 246174 534430 ~ 539694 (+)
G456911 NA non-coding downstream 10651 801660 ~ 801879 (+)
G456912 NA non-coding downstream 11151 802160 ~ 802388 (+)
G456892 NA non-coding downstream 89216 880225 ~ 882441 (+)
G456926 NA non-coding downstream 92374 883383 ~ 883820 (+)
G456928 NA non-coding downstream 94482 885491 ~ 885815 (+)
G456774 NA other upstream 358843 426083 ~ 427025 (+)
CI01000321_03795430_03804685 SHISA7B, SHISA7 other downstream 2998309 3792915 ~ 3805511 (+)
CI01000321_04013470_04014515 CACNG8 other downstream 3215617 4013468 ~ 4015412 (+)
G459303 NA other downstream 3694388 4485397 ~ 4488552 (+)
CI01000321_04515562_04517953 MRPS21 other downstream 3724525 4515534 ~ 4518187 (+)

Expression


Co-expression Network