CI01000325_02067666_02085794 (ESR2A, ESR2, ERBETA)


Basic Information

Item Value
gene id CI01000325_02067666_02085794
gene name ESR2A, ESR2, ERBETA
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000325
NCBI id null
chromosome length 10587162
location 2067666 ~ 2085794 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000325_02067666_02085794.mRNA
ATGTCCGAGTATCCAGAGGGAGAAAGCCCTCTGCTTCAGCTACAGGAAGTGGACTCCAGCAGGGTGGGAGGTCACGTCCTCTCACCTATCTTTAACTCCTCCTCTCCATCCCTGCCAGCGGAGAGCCATCCCATCTGTATCCCATCACCCTACACAGACCTCAGCCATGACTTCACCACTCTGCCCTTCTACAGTCCCGCTCTGCTGGGTTACGGCACATCGCCTCTGTCCGACTGCTCATCAGTGCGGCAGTCGCTAAGCCCTACCCTCTTTTGGCCACCTCATAGCCAAGTTTCATCACTTGCATTACATCAACAACAGACTCGATTACAACAAAACCATCCAACTGGTGGGACTTGGGCGGAACTTACACCATATGATCACGGCGAAGAGGAATACAGAAAACCACTGGTGAAGAGGGTAGCAGATTCAGAAGAGACTTCTACCTCTTCGAGAGGCAAAGCTGACATGCACTACTGTGCCGTTTGTAGTGATTATGCCTCTGGGTACCATTATGGTGTGTGGTCGTGTGAAGGATGCAAAGCCTTCTTCAAGAGGAGTATACAAGGACACAATGACTACATCTGCCCTGCCACCAACCAGTGCACCATCGACAAGAACCGCCGCAAAAGCTGCCAGGCCTGCCGACTCCGGAAGTGTTATGAAGTTGGAATGATGAAATGTGGGTTACGGCGAGATCGTGGCAGCTACCAACAAAGAGGAGCACAACAGAAGCGAATGGCACGATTCTCTGGCAGGATGAGAACAAGTGGCCCGAAATCTCAAGAGATGAAAAGTGTCCCACGTCCCCTCAGTGGAAATGAGGTGGTTACCATGGCGTTGAGCCCTGAGCAACTAATCGCTCGCATCATGGATGCAGAGCCACCTGAGATTTACCTCATGAAAGATGTGAAGAAGCCATTTACTGAGGCCAACGTCATGATGTCACTGACCAACCTAGCTGACAAAGAGCTCGTTCACATGATCAGCTGGGCCAAGAAGATCCCAGGTTTTGTGGAGCTCAGTCTTTTTGACCAGGTCCATTTGTTAGAGTGCTGCTGGTTAGAGGTGCTGATGTTGGGACTAATGTGGCGTTCTGTTAATCACCCTGGAAAGCTCATTTTCTCTCCAGACCTCAGTCTCAGCAGAGACGAAGGCAGCTGTGTGCAGGGGTTTGTGGAAATCTTTGATATGCTGCTGGCAGCCACGTCCAGATTCAGAGAACTCAAATTACAGAGAGAGGAGTATGTGTGTCTCAAAGCCATGATCCTCCTCAACTCCAACATGTGTCTGAGTTCGTCTGAGGGAGGAGAGGAACTGCAGAGCCGGTCGAAGCTGCTGTGTCTGCTGGACTCGGTGACGGATGCTCTGGTATGGGCCATCTCGAAGACAGGCTTGAGCTTTCAGCAGCGCTCCACCAGGCTAGCCCATCTGCTCATGCTGCTCTCCCACATAAGGCACCTCAGTAACAAAGGCATGGACCACCTCCACTGCATGAAGATGAAGAAGATGGTTCCTCTGTATGACCTGCTTCTGGAGATGCTGGACGCTCATATCATGCACAGCTCACGTCTGTCTCACTCCAGTCCACGAGAGAGCAAAGGCGTCCAGGAGGCCTTCATCTGCACTTCTCAGCATGGACCC

Function

symbol description
esr2a Enables estrogen receptor activity; nuclear receptor activity; and steroid binding activity. Acts upstream of or within response to estrogen. Predicted to be located in nucleus. Is expressed in several structures, including blastodisc; brain; pelvic fin bud; pleuroperitoneal region; and sensory system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); hypospadias; neurodegenerative disease (multiple); and ovarian dysgenesis 8. Orthologous to human ESR2 (estrogen receptor 2).
esr2 Enables several functions, including estrogen receptor activity; estrogen response element binding activity; and nuclear receptor activity. Involved in cellular response to lipid and regulation of transcription, DNA-templated. Located in mitochondrion and nucleus. Implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); hypospadias; neurodegenerative disease (multiple); and ovarian dysgenesis 8. Biomarker of several diseases, including Alzheimer's disease; Crohn's disease; aortic valve stenosis; autoimmune disease (multiple); and urinary bladder cancer.

NR:

description
estrogen receptor beta

GO:

id name namespace
GO:0043565 sequence-specific DNA binding molecular_function

KEGG:

id description
K08551 ESR2, NR3A2; estrogen receptor beta

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000325_02067666_02085794.mRNA True 1644 mRNA 0.52 8 2067666 2085794

Neighbor

gene id symbol gene type direction distance location
CI01000325_01944358_01986788 JAG2, JAG2B coding upstream 80878 1944358 ~ 1986788 (+)
CI01000325_01914049_01923709 NA coding upstream 142551 1913951 ~ 1925115 (+)
CI01000325_01662729_01717180 BRF1B, BRF1 coding upstream 350486 1662729 ~ 1717180 (+)
CI01000325_01578092_01612984 PPP1R13BB, PPP1R13B coding upstream 454682 1578092 ~ 1612984 (+)
CI01000325_01545056_01547234 RD3L coding upstream 519849 1545056 ~ 1547817 (+)
CI01000325_02211008_02215705 L3HYPDH coding downstream 123824 2209618 ~ 2215814 (+)
CI01000325_02399892_02431492 NA coding downstream 314098 2399892 ~ 2431492 (+)
CI01000325_02484476_02491983 KDR coding downstream 398682 2484476 ~ 2492226 (+)
CI01000325_02618395_02618952 NA coding downstream 531612 2617406 ~ 2619080 (+)
CI01000325_02751187_02751618 NA coding downstream 664540 2750334 ~ 2751683 (+)
G462972 NA non-coding upstream 15107 2052138 ~ 2052559 (+)
G462971 NA non-coding upstream 15531 2051818 ~ 2052135 (+)
G462969 NA non-coding upstream 17266 2050162 ~ 2050400 (+)
G462966 NA non-coding upstream 19807 2047578 ~ 2047859 (+)
G462951 NA non-coding upstream 38355 2029072 ~ 2029311 (+)
G462996 NA non-coding downstream 25692 2111486 ~ 2114394 (+)
G463001 NA non-coding downstream 33545 2119339 ~ 2119861 (+)
G463024 NA non-coding downstream 123050 2208844 ~ 2209176 (+)
G463056 NA non-coding downstream 202540 2288334 ~ 2356401 (+)
G463080 NA non-coding downstream 367192 2452986 ~ 2453229 (+)
G462928 NA other upstream 66782 2000477 ~ 2000884 (+)
G462778 NA other upstream 170851 1828082 ~ 1896815 (+)
G462730 NA other upstream 447472 1617596 ~ 1620194 (+)
G463566 NA other downstream 477361 2563155 ~ 2563735 (+)
G463724 NA other downstream 642412 2728206 ~ 2728450 (+)
G464950 NA other downstream 2972662 5058456 ~ 5090938 (+)
CI01000325_05549713_05553140 TMEM251 other downstream 3466326 5549713 ~ 5554577 (+)
CI01000325_05655953_05691697 PRIMA1 other downstream 3569618 5654840 ~ 5692630 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_017280 esr2a coding NC_007131.7 CM002904.2 21583639 ~ 21635659 (+)
bowfin (Amia calva) AMCG00000598 NA coding CM030141.1 CM030141.1 19001822 ~ 19023749 (-)