XLOC_013347 (bbs2)


Basic Information

Item Value
gene id XLOC_013347
gene name bbs2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 17516569 ~ 17531483 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00026390
GTCTGTCCTGCTAGGTAACAGGGCGAATAGCTACTGCACCTGGTAGAAGACAAGCTGGCGGCAGCGGAGCAGTTCTGATCTTGCACTTCTAGCTGAGCCACAATGCTAGTGCCCATCTTCACACTTAAACTGAACCATAAAATAAATCCTCGAATGGTTGCTATTGGAAAGTATGATGGAATACATCCATGCCTTACCGCAGCCACACAAGCAGGGAAGGTGTTTATCCACAACCCTCACACTCGAGCCCAGAGACCAACAGCCCACCGGTTGAGTCAAAGCACCCAGGACTCGGACATCTCACTGCTTAATATCAACCAGTCAGTCAGCTGTCTGACCGCTGGCACTTTAGGACCAAAGAGCACAGGGGACACGCTGCTCGTAGGCTCTCAAACCAACCTGTTGGCCTATGACGTTCATGACAACACCGACGTCTTTTACAAGGAGGTGACCGATGGGGCTAATGCCATTGTTTTGGGAAAACTAGGAGATATTCAATCACCCCTTGCCATCATTGGAGGAAACTGTGCTCTTCAAGGCTTTGACTATGAGGGAAATGACCTGTTCTGGACAGTCACTGGAGATAATGTTCGGTCACTTGTGCTTTGTGACTTCACTGCAGATGGCAAGAATGAGCTTCTTGTTGGCTCAGAAGACTTTGACATCAGGGTGTTTAAAGAGGATGAACTGGTGACTGAGATGGCAGAAAATGAGACAGTCACTTCGCTTTGCCACATGCACGGCAGCAGGTTTGGTTACGCTCTGGCCAATGGAACAGTAGGAGTGTATGACCGCACTGCCCGCTACTGGAGGATCAAGTCAAAAAATCATGCCATGAGTATCCACGCTTTTGACCTTAACGCTGATGGTGTTGTTGAGCTCATAACTGGATGGTCCAATGGAAAGATTGACGCTCGTAGTGATCGTACTGGTGAGGTGATCTTCAAGGATAACTTCTCATCCTCTGTGGCCGGGGTTGTTGAGGGAGATTatcggatggacggacagatccAGCTCATATGTACGTCTGTGGAGGGAGAAGTACGTGGCTACCTGCCTGCCAGTAAGGAGATGAAGGGAAACCTTATGGACTCAAGCATAGAACAAGACCTGATCAGAGAGCTGAGTCAACGGAAACAGAACTTGATGCTTGAGTTACGAAACTATGAGGAAAATGCCAAGGCTCTTCCTGGGCTTTCGGAGGGAGAATCTAAGATGGGTGTAATTCCAGCCAACACGCAGCTCCAGACGGCCCTCTCTGTAAGAAGAGCCTCGGAGAGCCAGAAAGCACACATAGAGCTCAACATCTCCACTCCAAATGAAACCATCATTAGAGCCGTACTGATATTTGCTGAAGGGATTTTTGAAGGTGAGAGTCATGTGGTTCACCCTAGTGCTCAGAATCTCTCCGGCTGTGTCCGAGTCCCCATTATTCCTCCAAAAGACATTCCAGTGGACCTTCATATCAAAGCCTTTGTGGGAGGAAAGACAAGTACACAGTTCCACGTTTTTGAGATCACACGTCAGCTGCCTCGCTTCTCCATGTATGACCTTAATGTTGATCCCTCAGCCCCAGAACCCACTGGAAAAGTCACATTCTGCATTAATGACAGACCTCAGAGGGTCGTCATGTGGCTAAACCAGAACTTCCTGCTCCCCGAGGGCATCGACAGTCCAGACGTCACCTTCAGTGCACTGCGAGGAGGAGGTCTGCTGAGAATCAGCTTGCAGACTAGTGGAGAGATCACACTGAGAACAGATGACATTGATCTGGCTGGAGATCTAGTCCAATCTCTTGCCTCTTTTTTGGCCATCGAAGACTTACAAGCTGAATCTGACTTTCCTGTCTACTTCAAAGAGCTGAGAGCAACTCTCACTGAGGTGGATGAGTTTCACTCAGTGCATCAAAAGCTCACAGCAGCAATGGCAGATCATTCCAACTACATACGAAATATGCTAGTGCAGGCGGAAGATGCCAGACTCATGGGCGATTGGAGAAACATGAAGAAACGCTACATTGAGCTGTATGACCTCAACCGAGACTTGGTTAATGAATATAAAATCAGGTCTAATAACCACAACGCCCTTCTCGCCCGGCTAAAATCAGTTAACCAGGCCATTCAAAGGGCAGGAAGGTTGAGAGTGGGAAAACCCAAATCACAGGTCATCACAGCTTGTCGGGATGCCATCAAGAACAACAACATAAATGCTCTTTTCAAGATCATGAGAGCTGGTACTACATCCTCCTGAGGAAGATCTGGGCCTAAATGACCTTCAAATGCAGAAGTCTGGAAGATCAGACCAAGTCCCTGATTGGAAATCTTGGAAAGTGGTCAGAAGCCTGATGGAAAATGGGGTAAAGCCTAAATGAGGGAATATATTCAAAATCCAGCTCTCACAGAAAGCAGTTTTGTGTTAGAGGAATAACTGAGTTGATCAATCATGCAGAGACCGTAAAGTGTGTTAGCCAAAATGATAGCCAAAGAGACTGTATTTTCTGTACAAATTCAATGTGTGTGCAAGTCGACTGGCATTGTCTGGacgaattaaattattataaaaatacatttgttttca
>TCONS_00026391
GGAGCAGTTCTGATCTTGCACTTCTAGCTGAGCCACAATGCTAGTGCCCATCTTCACACTTAAACTGAACCATAAAATAAATCCTCGAATGGTTGCTATTGGAAAGTATGATGGAATACATCCATGCCTTACCGCAGCCACACAAGCAGGGAAGGTGTTTATCCACAACCCTCACACTCGAGCCCAGAGACCAACAGCCCACCGGTTGAGTCAAAGCACCCAGGACTCGGACATCTCACTGCTTAATATCAACCAGTCAGTCAGCTGTCTGACCGCTGGCACTTTAGGACCAAAGAGCACAGGGGACACGCTGCTCGTAGGCTCTCAAACCAACCTGTTGGCCTATGACGTTCATGACAACACCGACGTCTTTTACAAGGAGGTGACCGATGGGGCTAATGCCATTGTTTTGGGAAAACTAGGAGATATTCAATCACCCCTTGCCATCATTGGAGGAAACTGTGCTCTTCAAGGCTTTGACTATGAGGGAAATGACCTGTTCTGGACAGTCACTGGAGATAATGTTCGGTCACTTGTGCTTTGTGACTTCACTGCAGATGGCAAGAATGAGCTTCTTGTTGGCTCAGAAGACTTTGACATCAGGGTGTTTAAAGAGGATGAACTGGTGACTGAGATGGCAGAAAATGAGACAGTCACTTCGCTTTGCCACATGCACGGCAGCAGGTTTGGTTACGCTCTGGCCAATGGAACAGTAGGAGTGTATGACCGCACTGCCCGCTACTGGAGGATCAAGTCAAAAAATCATGCCATGAGTATCCACGCTTTTGACCTTAACGCTGATGGTGTTGTTGAGCTCATAACTGGATGGTCCAATGGAAAGATTGACGCTCGTAGTGATCGTACTGGTGAGGTGATCTTCAAGGATAACTTCTCATCCTCTGTGGCCGGGGTTGTTGAGGGAGATTatcggatggacggacagatccAGCTCATATGTACGTCTGTGGAGGGAGAAGTACGTGGCTACCTGCCTGCCAGTAAGGAGATGAAGGGAAACCTTATGGACTCAAGCATAGAACAAGACCTGATCAGAGAGCTGAGTCAACGGAAACAGAACTTGATGCTTGAGTTACGAAACTATGAGGAAAATGCCAAGGCTCTTCCTGGGCTTTCGGAGGGAGAATCTAAGATGGGTGTAATTCCAGCCAACACGCAGCTCCAGACGGCCCTCTCTGTAAGAAGAGCCTCGGAGAGCCAGAAAGCACACATAGAGCTCAACATCTCCACTCCAAATGAAACCATCATTAGAGCCGTACTGATATTTGCTGAAGGGATTTTTGAAGGTGAGAGTCATGTGGTTCACCCTAGTGCTCAGAATCTCTCCGGCTGTGTCCGAGTCCCCATTATTCCTCCAAAAGACATTCCAGTGGACCTTCATATCAAAGCCTTTGTGGGAGGAAAGACAAGTACACAGTTCCACGTTTTTGAGATCACACGTCAGCTGCCTCGCTTCTCCATGTATGACCTTAATGTTGATCCCTCAGCCCCAGAACCCACTGGAAAAGTCACATTCTGCATTAATGACAGACCTCAGAGGGTCGTCATGTGGCTAAACCAGAACTTCCTGCTCCCCGAGGGCATCGACAGTCCAGACGTCACCTTCAGTGCACTGCGAGGAGGAGGTCTGCTGAGAATCAGCTTGCAGACTAGTGGAGAGATCACACTGAGAACAGATGACATTGATCTGGCTGGAGATCTAGTCCAATCTCTTGCCTCTTTTTTGGCCATCGAAGACTTACAAGCTGAATCTGACTTTCCTGTCTACTTCAAAGAGCTGAGAGCAACTCTCACTGAGGTGGATGAGTTTCACTCAGTGCATCAAAAGCTCACAGCAGCAATGGCAGATCATTCCAACTACATACGAAATATGCTAGTGCAGGCGGAAGATGCCAGACTCATGGGCGATTGGAGAAACATGAAGAAACGCTACATTGAGCTGTATGACCTCAACCGAGACTTGGTTAATGAATATAAAATCAGGTCTAATAACCACAACGCCCTTCTCGCCCGGCTAAAATCAGTTAACCAGGCCATTCAAAGGGCAGGAAGGTTGAGAGTGGGAAAACCCAAATCACAGGTCATCACAGCTTGTCGGGATGCCATCAAGAACAACAACATAAATGCTCTTTTCAAGATCATGAGAGCTGGTACTACATCCTCCTGAGGAAGATCTGGGCCTAAATGACCTTCAAATGCAGAAGTCTGGAAGATCAGACCAAGTCCCTGATTGGAAATCTTGGAAAGTGGTCAGAAGCCTGATGGAAAATGGGGTAAAGCCTAAATGAGGGAATATATTCAAAATCCAGCTCTCACAGAAAGCAGTTTTGTGTTAGAGGAATAACTGAGTTGATCAATCATGCAGAGACCGTAAAGTGTGTTAGCCAAAATGATAGCCAAAGAGACTGTATTTTCTGTACAAATTCAATGTGTGTGCAAGTCGACTGGCATTGTCTGGacgaattaaattattataaaaatacatttgttttc

Function

symbol description
bbs2 Acts upstream of or within several processes, including Kupffer's vesicle development; cilium assembly; and establishment of pigment granule localization. Predicted to be located in ciliary membrane; cytoplasm; and cytoskeleton. Predicted to be part of BBSome. Predicted to be active in several cellular components, including ciliary basal body; motile cilium; and neuron projection. Is expressed in retina and retinal photoreceptor layer. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 2; obesity; and retinitis pigmentosa 74. Orthologous to human BBS2 (Bardet-Biedl syndrome 2).

GO:

id name namespace
GO:1905515 non-motile cilium assembly biological_process
GO:0046907 intracellular transport biological_process
GO:0032402 melanosome transport biological_process
GO:0070121 Kupffer's vesicle development biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0007369 gastrulation biological_process
GO:0051877 pigment granule aggregation in cell center biological_process
GO:0060271 cilium assembly biological_process
GO:0031514 motile cilium cellular_component
GO:0042995 cell projection cellular_component
GO:0034464 BBSome cellular_component
GO:0043005 neuron projection cellular_component
GO:0036064 ciliary basal body cellular_component
GO:0060170 ciliary membrane cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005929 cilium cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component

KEGG:

id description
ko03036 Chromosome and associated proteins

ZFIN:

id description
ZDB-GENE-020801-1 Acts upstream of or within several processes, including Kupffer's vesicle development; cilium assembly; and establishment of pigment granule localization. Predicted to be located in ciliary membrane; cytoplasm; and cytoskeleton. Predicted to be part of BBSome. Predicted to be active in several cellular components, including ciliary basal body; motile cilium; and neuron projection. Is expressed in retina and retinal photoreceptor layer. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 2; obesity; and retinitis pigmentosa 74. Orthologous to human BBS2 (Bardet-Biedl syndrome 2).

Ensembl:

ensembl_id ENSDARG00000041621

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00026390 False 2577 mRNA 0.47 18 17516569 17531483
TCONS_00026391 True 2511 mRNA 0.47 17 17516570 17529763

Neighbor

gene id symbol gene type direction distance location
XLOC_013346 b3gnt9 coding downstream 3143 17511995 ~ 17513426 (-)
XLOC_013345 NA coding downstream 23863 17491321 ~ 17492706 (-)
XLOC_013344 foxl1 coding downstream 31150 17483557 ~ 17485419 (-)
XLOC_013343 ces2a coding downstream 100960 17408470 ~ 17415609 (-)
XLOC_013342 zfpm1 coding downstream 117193 17270427 ~ 17399376 (-)
XLOC_013348 psme3ip1 coding upstream 176205 17707688 ~ 17724295 (-)
XLOC_013349 NA coding upstream 246044 17777527 ~ 17786790 (-)
XLOC_013350 CR387935.1 coding upstream 555777 18087260 ~ 18122969 (-)
XLOC_013351 NA coding upstream 580511 18111994 ~ 18113888 (-)
XLOC_013352 lonp2 coding upstream 944191 18475674 ~ 18524624 (-)
XLOC_013384 BX323829.1 misc upstream 2010619 19542102 ~ 19542231 (-)
XLOC_013329 NA non-coding downstream 1139228 16372210 ~ 16377341 (-)
XLOC_013327 NA non-coding downstream 1208632 16224790 ~ 16307937 (-)
XLOC_013324 NA non-coding downstream 1498482 15991454 ~ 16018087 (-)
XLOC_013323 NA non-coding downstream 1545996 15939261 ~ 15970573 (-)
XLOC_013355 BX470163.3 non-coding upstream 1037758 18569241 ~ 18569322 (-)
XLOC_013356 BX470163.2 non-coding upstream 1045991 18577474 ~ 18577549 (-)
XLOC_013357 BX470163.1 non-coding upstream 1046331 18577814 ~ 18577894 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_05572116_05579830 BBS2 coding CI01000013 null 5571340 ~ 5580139 (+)