XLOC_013353 (il34)


Basic Information

Item Value
gene id XLOC_013353
gene name il34
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 18527170 ~ 18543358 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00026397
ACGCGCGGAGAGAGCTGTAGGCGGGTGTTGTATGTACAGCGGCTTAACATACAGAAGAGGTGACATAAAGAAAGGGAGTTTCCGACGCTTTTGGGTGGACGGTGCATAGAAAAGGGGGCGATTTTACTACTTCGGTCAGTATCCTGCACGCCTGGAAGTGTCAGCGGTCATATCTTCAGGGTTAAGCAAACACTTGCCTGTTTACTGAAAGTCCTCTGCAGATGGTTCCCACTGAGGCAGACTAGAACATCGAATCGAAAGaacaagAGGACCTAACAATTTCCTTTAATCAAGATCTAGATCACAGAAAAAACGTCCTACCATGGTCCAGTCCGAATGCTGGCTTCTCAGGGGGCTGCTGGGTTTTATTTGTCTATTACCAGTGTGCAGTAGTGCAGCTCCAGATCTCTGTGGACCTCTGAAAACAGTCCAAGACAGTCTAAATGCAACCTTAAGGAGACGTTATATGaaaaTGCACTTTCCCATTAATTACACTGTCCAAGTGCGTTATGAGGAGGTGTTCAGACTGCGAAACATCAGCAGACTGGTGAATACGAGTAATGAAGAAGAGCCAGTGCTGCCGAGAGATCTCCAGGATTTGTGGCTTTACGTGAGTCAACAGGGCATTAAGAAGGTCTTACGGGTACTGCCAGAGAGGCATCCAACGCGGCGTAAATACCTCTCTGATCTGGAGAATCTCTTTAAAAAATTTGAGACGGTTTTTAAAGAAGGGAATCACGAAGACCAAGAGAATGTCAGAGAACGTCCAGAGAGCTTACAAACCATCTGGGATCACTTGACGGAACAAGATTATAAAGGATGGAAGTCAGTCACACCCAAATCAATCCTTGATAACTGTTATCGGACCATGCTTTGCCTGTTTAAAGAGTGCTTCACAAAAGAGGATGACAATTATGATTATTGTGAAGTCTATAACAGGAGGAAAGAAAGGAAAACAACATAGCAGCAGATCTTAGCGGATCTAATCCTGTCTCCGTGTTGCTGTTGTAGGGTGTTAACTGGTTTATGTAGTGACACGCAGCATGCTTGTGTGCCTCTTGTCCTATTGAAGTCATGGACTGCCTCCACCGGTGTTTGCCATATTGAAAAACACAGCAGCAGTCAAACCACTTGGAAGACACTCTACTGACCCTGCAGCTATTGCTCTCCGTCATTCAAACCTCCATACATCCACCCGCCCGCCATCTTGCATATTTAGGCAGCATTTTGCTAATAAATCTTCATGTGTGCAGTGCACTGTGCGTGTGCTTTTATGGAGGAGAGCAGCTTTGGCTAATTGCTGTAGCATTTTATATTGGTTATTTCCACAAAAAGTCTTTGCACTGTGACTTTTATTTCTGAGgaaattagatattttttcacATGCCAAAGCAGTATGTTAGCATTGCCGTGTTGTAAATGTCAGTTAGGTGAGATGTAAAAAAACGTGGAGCTTCTTTTTGTACACATTTCATTAGCATGCAAATCTTGTGCTGACTGCTGGCTTAGTCGGCACTGTTGCTTTTACCCGGAGACTGTTTACTTTTGTGCTTTATTGCTGTTTCAATGTTGAAAGACTGCACCAAAGTACTcctgttaaacttttttttctaaaagattGATCGAGAGGGTTTGATATCAGgtttgcatatgttttatacacagATTTTTTAATGTAGGTTATTTATTTGGACTCCTGCCACAGAATGTTCTGGTAACTGTTGTAACTTGGCTTAGGGAATAAACTTCTCACTATCA

Function

symbol description
il34 Predicted to enable cytokine activity and macrophage colony-stimulating factor receptor binding activity. Acts upstream of with a positive effect on macrophage migration. Acts upstream of or within microglia development. Predicted to be active in extracellular space. Orthologous to human IL34 (interleukin 34).

GO:

id name namespace
GO:0014005 microglia development biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0045651 positive regulation of macrophage differentiation biological_process
GO:0045657 positive regulation of monocyte differentiation biological_process
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0005157 macrophage colony-stimulating factor receptor binding molecular_function

KEGG:

id description
ko04060 Cytokine-cytokine receptor interaction
ko04061 Viral protein interaction with cytokine and cytokine receptor
ko04052 Cytokines and growth factors

ZFIN:

id description
ZDB-GENE-050419-150 Predicted to enable cytokine activity and macrophage colony-stimulating factor receptor binding activity. Acts upstream of with a positive effect on macrophage migration. Acts upstream of or within microglia development. Predicted to be active in extracellular space. Orthologous to human IL34 (interleukin 34).

Ensembl:

ensembl_id ENSDARG00000091003

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00026397 True 1758 mRNA 0.43 7 18527170 18543358

Neighbor

gene id symbol gene type direction distance location
XLOC_013352 lonp2 coding downstream 2546 18475674 ~ 18524624 (-)
XLOC_013350 CR387935.1 coding downstream 404201 18087260 ~ 18122969 (-)
XLOC_013351 NA coding downstream 413282 18111994 ~ 18113888 (-)
XLOC_013349 NA coding downstream 740380 17777527 ~ 17786790 (-)
XLOC_013348 psme3ip1 coding downstream 802875 17707688 ~ 17724295 (-)
XLOC_013354 sf3b3 coding upstream 3665 18547023 ~ 18587745 (-)
XLOC_013355 BX470163.3 coding upstream 25883 18569241 ~ 18569322 (-)
XLOC_013356 BX470163.2 coding upstream 34116 18577474 ~ 18577549 (-)
XLOC_013357 BX470163.1 coding upstream 34456 18577814 ~ 18577894 (-)
XLOC_013358 NA coding upstream 85708 18629066 ~ 18634673 (-)
XLOC_013384 BX323829.1 misc upstream 998744 19542102 ~ 19542231 (-)
XLOC_013345 NA non-coding downstream 1034464 17491321 ~ 17492706 (-)
XLOC_013329 NA non-coding downstream 2149829 16372210 ~ 16377341 (-)
XLOC_013327 NA non-coding downstream 2219233 16224790 ~ 16307937 (-)
XLOC_013360 BX649641.5 non-coding upstream 152849 18696207 ~ 18701764 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_04943413_04948991 IL34 coding CI01000013 null 4943413 ~ 4949256 (+)