XLOC_013394 (wnt2)


Basic Information

Item Value
gene id XLOC_013394
gene name wnt2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 20613241 ~ 20636549 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00026463
AGGCGGGTCTGCAGCGCTGCTCTCCGCGATGCTCTGACGCTCAGCTCGCCCGCGTCGCGTCGCGTCACTCCGGCGTTCATCCGCTCTCACCGCCTCAGCTCTTCATGCCCTCCGTGTTTTATTTATGTGCTGTTAAAACCCGTAGACAAGTGCCTGAACGAATGAGTATCAATACAATTTTTAGAATATGAACTTTTTGCCAAATGGAATATGTTTCTATCTGTCCGTGGCAATTTGCTGGTTCTCATCCAGAGTCGACGCGTCGTGGTGGTACATGGGCACTCTTGGATCGCAAGTGATGTGCGACAACATCCCGGGTTTAATTAACAAACAGCGCCAGTTGTGCCGCCAGCATCCCAAAGTGATGCAGGCTATAGGAGCTGGCATCAAAAACTGGATTGGCGAATGTCAGCACCAGTTCAGGACCCACCGCTGGAACTGTAACACCATGGCACGCGAGCACAATCTGTTCGGGAGGCTCCTGCACCGCAGCAGTCGTGAGGCAGCTTTTGTCTATGCCATCTCCTCAGCTGGTATGGTCTACACATTGACCAGGGCGTGCAGTCAGGGTGAGCTGGAAAACTGCTCATGTGACCCTGGAAAAAAAGGCTCATCCCGCGATGCCAAGGGAGCTTTTGACTGGGGGGGCTGCAGTGATCACGTTGACCATGCCATCAAGTTCACCCAGGTCTTCATTGATGCCAAAGAGAGGAAAGAGAGAGATGCCCGGGCACTCATGAACCTGCACAACAACCGAGCAGGGAGGAAGGCGGTGAAGCGCTTTATGAATCTGGAGTGTAAGTGTCATGGTGTCAGTGGCTCATGCAACGTCCGCACCTGCTGGTTAGCCATGGCTGACTTCAGGCAGACGGGTGACTATCTTCGCAAAAAATACAACAACGCCATTCAGGTGGTGATGAACCAATATGGGACGGGCTTCACCAGCGCATACAGGATGTTAAAGAGGCCTAACAAAAATGACCTGGTCTACTTTGAAGACTCGCCTGACTACTGTATATGGGACCATGAGTCTGGTTCGGTGGGCACCGGTGGGCGAGTGTGCAACCGCACGTCACGCGGTACTGACAGCTGTGAGGTCATGTGTTGTGGGCGGGGCTACGACACATCAAGAGTGAGTCGCACAACCAAGTGTGAGTGTAAGTTCCAGTGGTGCTGTGCTGTTCACTGCAGGGACTGTCAAGAAGAGGTGGACGTGCACACCTGCAAAACCCAGTCCTGATCAAACCACTTCTACATCGCTTTTTTATTGTGGCTCGTTGGAGAAATATACGTACACAACATGACCAGCAACTTCAAAACAATGCTGATTTGAAGCCTTAACTAGCTTTACCGTCTTTATTCGCTGTTTTGTTTATTACTCTGTCATAACACAGATATTTATTACTGCTTTGGAGCGTAAGAATGTTTATCTTTAATGTATTTTCGTATGTtgaaatgtaaatacaaactttatgtaatttaaaataaaatgtacacgtATGTAACAAA

Function

symbol description
wnt2 Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within hepatocyte proliferation and swim bladder development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including nervous system; optic cup; optic vesicle; otic vesicle; and swim bladder bud. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system cancer. Orthologous to human WNT2 (Wnt family member 2).

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0048794 swim bladder development biological_process
GO:0030182 neuron differentiation biological_process
GO:0045165 cell fate commitment biological_process
GO:0007275 multicellular organism development biological_process
GO:0001889 liver development biological_process
GO:0072574 hepatocyte proliferation biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0005109 frizzled binding molecular_function
GO:0005125 cytokine activity molecular_function

KEGG:

id description
ko04310 Wnt signaling pathway
ko04390 Hippo signaling pathway
ko04150 mTOR signaling pathway
ko04550 Signaling pathways regulating pluripotency of stem cells
ko04916 Melanogenesis
ko05200 Pathways in cancer
ko05205 Proteoglycans in cancer
ko05225 Hepatocellular carcinoma
ko05226 Gastric cancer
ko05217 Basal cell carcinoma
ko05224 Breast cancer
ko05165 Human papillomavirus infection
ko05010 Alzheimer disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko04934 Cushing syndrome
ko00536 Glycosaminoglycan binding proteins

ZFIN:

id description
ZDB-GENE-980526-416 Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within hepatocyte proliferation and swim bladder development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including nervous system; optic cup; optic vesicle; otic vesicle; and swim bladder bud. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system cancer. Orthologous to human WNT2 (Wnt family member 2).

Ensembl:

ensembl_id ENSDARG00000041117

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00026463 True 1509 mRNA 0.49 5 20613241 20636549

Neighbor

gene id symbol gene type direction distance location
XLOC_013393 bcl2l13 coding downstream 4941 20581685 ~ 20608300 (-)
XLOC_013392 dennd11 coding downstream 53182 20541316 ~ 20560059 (-)
XLOC_013391 ighmbp2 coding downstream 80902 20516527 ~ 20532339 (-)
XLOC_013390 paqr5a coding downstream 147180 20459888 ~ 20466061 (-)
XLOC_013389 kif23 coding downstream 154401 20435821 ~ 20458840 (-)
XLOC_013396 asz1 coding upstream 5829 20642378 ~ 20674121 (-)
XLOC_013397 cttnbp2 coding upstream 89600 20726149 ~ 20822045 (-)
XLOC_013398 BX470160.1 coding upstream 209641 20846190 ~ 20846313 (-)
XLOC_013399 synm coding upstream 223112 20859661 ~ 20869175 (-)
XLOC_013400 igf1ra coding upstream 244913 20881462 ~ 21047580 (-)
XLOC_013384 BX323829.1 misc downstream 1071010 19542102 ~ 19542231 (-)
XLOC_013388 NA non-coding downstream 293368 20285665 ~ 20319873 (-)
XLOC_013387 NA non-coding downstream 464144 20140072 ~ 20149097 (-)
XLOC_013386 NA non-coding downstream 728947 19883591 ~ 19884294 (-)
XLOC_013381 CT863714.7 non-coding downstream 1158000 19455144 ~ 19455241 (-)
XLOC_013380 NA non-coding downstream 1158374 19454800 ~ 19454867 (-)
XLOC_013411 BX548157.1 non-coding upstream 1075747 21712296 ~ 21720051 (-)
XLOC_013417 CT573204.2 non-coding upstream 1447223 22083772 ~ 22083886 (-)
XLOC_013420 CR933017.1 non-coding upstream 1914046 22550595 ~ 22552314 (-)
XLOC_013426 BX088710.1 non-coding upstream 2103183 22739732 ~ 22753637 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_03843207_03852634 WNT2 coding CI01000013 null 3843207 ~ 3854025 (+)