XLOC_013405 (got2a)


Basic Information

Item Value
gene id XLOC_013405
gene name got2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 21178721 ~ 21188768 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00026477
GGCGCTATAAGCAACAAAAGCAGCACACAAGTTCAACTTCACACACACTGTGCGTTTGTCTTCCAGCAAGTCACCTGCGCTTCCAGCAATGGCCCTGTTCAAATCCAGCAAGATTTTGTCTAGTGTCGGGTCTCAGACCCCTGTTTTAGCAGTCTTACAGCTCCGGGCAAGctcATGGTGGACTGAGGTACAGATGGGACCCCCTGATCCCATCCTGGGGGTCACGGAGGCTTTTAAGCGTGACACCAACCCCAAGAAGATGAACCTTGGAGTTGGAGCTTATAGAGATGATCAGGGGAAGCCATTCGTCCTCAGCAGTGTTCGAAAGGCTGAAGCCCAGATTGCTGCTAAGAAGTTGGATAAAGAGTACCTTCCTATTGGAGGTTTGGCAGACTTTTCAAAGGCCTGTGTTCAGCTGGCTCTTGGACCTGATAACGAGGTCTTGAAGAGCGGCAGAAGCATCACTGTCCAGACTATCTCAGGAACTGGATCTCTACGTATTGGAGCTAACTTTGTGtcACGATTCCACAATGCGTCCCGGGATGTGTACCTGCCTAAACCCTCTTGGGGCAACCACACACCAGTCTTTAGAGATGCAGGCATGCAGCTAAAGGCTTACACCTACTATGAACCCAAAACCTGTGGCTTTAATCTTAAAGGAGCCTTGGATGACATTTCAAAAATCCCTGAGAAGAGTGTAATTCTTCTTCATGCCTGCGCTCATAATCCCACCGGAGTGGACCCCAGGCCTGAGCAGTGGAAAGAGATGGCTGCTCTGATCAAGAAAAGAAATCTCCTGGTGTTCTTTGACATGGCTTACCAGGGATTTGCCAGTGGCGACATTGATCGTGACGCTTGGGCTGTGCGTTATTTCATTGAGCAGGGCCACAACATTCTACTGTCCCAGTCTTTTGCTAAGAACATGGGCCTGTATGGTGAGCGTGTGGGAGGCTTCACAGTGGTTTGTAAGGATGCCGAAGAGGCCAAGCGTGTGGAATCTCAGCTGAAAATCCTCATTCGGCCCATCTACTCCAACCCACCCATGAATGGCGCTCGCATCGCCGCCACTATCCTCAACACACCTGAACTCTACAAAGAATGGCTTCAGGAGGTAAAAGGCATGGCTGACCGCATCATTAGGATGAGAGAGATGCTCGTTTCCAACCTTAAAAAGGAGGGCTCCACTCACAACTGGCAACATGTCACTGACCAGATCGGGATGTTCTGCTTCACTGGGCTCAAACCGGAACAGGTGGAGCGTCTGATTAATGAATTCTCTATATACATGACAAAAGATGGCCGGATTTCTGTGGCCGGAGTGACGTCTGCCAACGTGGAGTATCTTGCACATGCCATCCACGCCGTCACCAAGTGAAGCTAGCATCAAACGTAGTGATGATTTAATGTCTGTCAGGACCAGATAAGACATAGGATGAATGTAGACTTCCAGTTCACTTGATTTGGCATTATTAATGGTAATACATGACTGTGAATATGAGCCCTGCAATAAATTAAGACAGGATGCTTCCTttcaaaatgataaaaacaagctTTAAAGGATGTTGCTTATCATTGTTTCCTTTGTCGGAACTGATAAGAAGGTTTTTATGGTCTAAAAGTCTAACATGctttaaaaatctttttgtttttCAGACAAATGACTCTAAATGAGAATAATAACTCAGtatgaaataataacaataaccattTTGAATGATTACCCATATACTCATGTAACTGAAAGGAGTGCACTGATTTCATGTTTTGATGATTGCATCATCTTTGAATGACTGTTGCCAGTCTCATGTTCATTTCACCTAGAACTTTAGCACTTCTTCTAAACATAGTTATTGTGAGTTTGCTACTAGTGGTGGaagattgtccatagtgtgtgcaATATATTTGTTCTCATGCAGCTTGtcagatttattttacttttctggCTAGAATTTTTCATGCATCACACACAGATAGTTTCATAAATTGATATAGgcatttacattcattttgtgttttgttctggCCATTTAaagggtagttcactcaaaatttgtCACCCTCAAGACCTTCTAAatggtttgtttttttctactgaacACAAACGAAGATCCTTTTCAGATTATGAGAAATTGGTACCCATTGACATCTAAAACATTCAATAGCTTCTGGTTTCAACATTCTTCTGAAAGTCTTGTTGGGTGTTAAAAATGatgacaattacattttttttgagtgaactattaaTCTCATTCATCATGTGTTAAACATACTGCATGTGAACAAAATCAAATGAAGattcattttagaattaaaaCCTATTTGAAATTGTAACTGATATATCAGTGGTTAATGATGCTTTAAGAAAAGCTCTCACCTGTGTGAATCTTGATTACATAAACATGCACTTTGTgaggataaataaaacaaaagtgctGACGAATATATTTGTATAATTGTGTATTGTGTTCCTGTGGTTAATTGTATTTCCCTCAAGATTTCTCCAAAATGATGAAGTGTCATGAGTGGTGCTCTATGAAtcctatttaaatgaataaaagtgaGCTCAACAAAAa

Function

symbol description
got2a Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate catabolic process. Predicted to act upstream of or within biosynthetic process and cellular amino acid metabolic process. Predicted to be located in mitochondrial matrix and plasma membrane. Predicted to be active in mitochondrion. Used to study developmental and epileptic encephalopathy 82 and early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2).

GO:

id name namespace
GO:0009058 biosynthetic process biological_process
GO:0006520 cellular amino acid metabolic process biological_process
GO:0006533 aspartate catabolic process biological_process
GO:0005759 mitochondrial matrix cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0005739 mitochondrion cellular_component
GO:0016740 transferase activity molecular_function
GO:0030170 pyridoxal phosphate binding molecular_function
GO:0008483 transaminase activity molecular_function
GO:0016212 kynurenine-oxoglutarate transaminase activity molecular_function
GO:0004069 L-aspartate molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-2703 Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate catabolic process. Predicted to act upstream of or within biosynthetic process and cellular amino acid metabolic process. Predicted to be located in mitochondrial matrix and plasma membrane. Predicted to be active in mitochondrion. Used to study developmental and epileptic encephalopathy 82 and early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2).

Ensembl:

ensembl_id ENSDARG00000041068

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00026477 True 2573 mRNA 0.42 10 21178721 21188768

Neighbor

gene id symbol gene type direction distance location
XLOC_013404 si:dkey-12e7.4 coding downstream 1047 21171465 ~ 21177674 (-)
XLOC_013403 BX571884.2 coding downstream 8457 21164591 ~ 21170264 (-)
XLOC_013402 si:dkey-12e7.1 coding downstream 72753 21101835 ~ 21105968 (-)
XLOC_013401 anpepa coding downstream 81058 21077528 ~ 21097663 (-)
XLOC_013400 igf1ra coding downstream 131141 20881462 ~ 21047580 (-)
XLOC_013406 calb2a coding upstream 9994 21198762 ~ 21218851 (-)
XLOC_013407 pnp6 coding upstream 68493 21257261 ~ 21271373 (-)
XLOC_013408 slc38a8a coding upstream 433646 21622414 ~ 21640389 (-)
XLOC_013409 mbtps1 coding upstream 456541 21645309 ~ 21685055 (-)
XLOC_013410 fan1 coding upstream 497347 21686115 ~ 21725805 (-)
XLOC_013384 BX323829.1 misc downstream 1636490 19542102 ~ 19542231 (-)
XLOC_013398 BX470160.1 non-coding downstream 332408 20846190 ~ 20846313 (-)
XLOC_013395 BX470130.1 non-coding downstream 544798 20633789 ~ 20633923 (-)
XLOC_013388 NA non-coding downstream 858848 20285665 ~ 20319873 (-)
XLOC_013387 NA non-coding downstream 1029624 20140072 ~ 20149097 (-)
XLOC_013386 NA non-coding downstream 1294427 19883591 ~ 19884294 (-)
XLOC_013411 BX548157.1 non-coding upstream 523528 21712296 ~ 21720051 (-)
XLOC_013417 CT573204.2 non-coding upstream 895004 22083772 ~ 22083886 (-)
XLOC_013420 CR933017.1 non-coding upstream 1361827 22550595 ~ 22552314 (-)
XLOC_013426 BX088710.1 non-coding upstream 1550964 22739732 ~ 22753637 (-)
XLOC_013427 BX663522.1 non-coding upstream 1670711 22859479 ~ 22862467 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_03493064_03499971 GOT2, GOT2A, GOT2B coding CI01000013 null 3493064 ~ 3500131 (+)
bowfin (Amia calva) AMCG00020393 got2,got2a,LOC107694944,LOC107596935,LOC107738675,LOC107672286,LOC107726360,LOC107707915 coding CM030127.1 CM030127.1 17917969 ~ 17926416 (+)