XLOC_013409 (mbtps1)



Basic Information


Item Value
gene id XLOC_013409
gene name mbtps1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 21645309 ~ 21685055 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00026482
GTTGTGTTTAATACCAGTTTCTCACATTACAGTCTTACAGCTTACGCCATTAGCTTGTGAATAGTTGTAATATGTATTAAGACAAAGATACAAACAGATCTCAGACGACTTATTACTGGAATAATCATTTCCTGCACCGTCGTTGTACATTCCGCAGATAAAGAATAGAAGGCCTTTAGTCACTGTGAGGAACCCATCACCAGATGAACGCCCCTCCTAATCTACTGTAGTTTGTTTGACTCTGCTGAAGAAGATGGTCCCTCTCCTCATCCTCAGACTGCCACACTGATCACCTTCACAGCACCACAAACACACAATGGAGAGGAAACGCCGAAAGAAATGAAAACTCAAGCCATGTGTTATTCAGGCTTCTCTGCGTTTTGGACCTAAACTATTTCAAAACTAATACACGTTTGTTACCTTTGATTACACTGACCGCAGGGATCATGATCGTAAGGCTGTGCTTGCTTGTGGCCTTTTTAGGGGCTAAATTGCCTCTGGTGGGCACAGAGGAAGACAGTGGACCGTTCTTAACCCcctttcctcctcctcttcctctaaATGCTGATGCACATTTGAGCCCAAACTGCTCACAGCTCACGCTAAAACTGGACTTCTCAACCCAAGTGGTCAAGCATGAGTACATTGTTGCGTTTAATGGATACTTCACAGCTAAAGCACGCAGTGATTTCATCAGCAGCGCCCTGCGGGATGTGGATGCAGTGAAATGGCGCATCGTACGGAGGGACAATCCTGCCAGCGATTaccccagtgattttgaggtGGTGGAGATCAAGCAGGACACACGCAACAGCCTGCTCACCCTCCAGGACCACCCCTATATCAAACGTGTGACGCCACAGCGCATGGTCCTCCGCAGCCTTAAATTCACAGACTCTGGCACTGATGGGGCGTCCCCATGCAATGACACACGCTGGGTGCAGAAGTGGCAGTCGTGGCAGTCATCAAGGCCACTCAGGAGGACTAGTCTGTCTCTGAGCTCTGGTTTCTGGCACGCCACAGGAAGACACTCTAGTCGGCGTCTCCTGCGTGCCATTCCCAGACATGTCGCCCAGATACTGCAAGCAGATGTGCTCTGGCAGATGGGACACACTGGCTCTGGAGTGAAGGTAGCGGTATTTGACACTGGGTTGAGTGAGAAGCACCCtcactttaaaaatgttaaagaaagAACCAACTGGACCAATGAGAAAACGCTGGATGATGGGTTGGGTCATGGCACATTTGTTGCTGGTGTGATTGCCAGCATGAGAGAGTGTCAGGGATTCGCTCCTGATTCTGAGCTACATATCTTCAGAGTTTTCACTAATAACCAGGTTTCATACACCTCCTGGTTCTTGGATGCCTTTAACTACGCTATCCTGAAGAAGATAGATGTTTTAAATCTCAGCATTGGGGGACCAGATTTTATGGACCATCCGTTCGTTGATAAGGTTTGGGAGCTCACAGCCAACAAGGTGATTATGGTGTCTGCTATCGGCAATGATGGCCCACTTTATGGaACTCTAAACAATCCAGCAGATCAAATGGATGTTATAGGTGTTGGAGGGATTGATTTTGAGGACAACATTGCCAGGTTTTCATCCCGGGGCATGACAACATGGGAGCTACCGGGGGGCTATGGCAGGGTGAAGCCTGACATCGTGACGTACGGCTCTGGTGTACGCGGTTCTGGATTGAAGGAGGGCTGTCGATCTCTCTCTGGCACTAGTGTTGCATCACCTGTTGTGGCAGGAGCTGTCACACTGCTGGCCAGCACTGTGTTGAACAGAGAGTTGGTGAATCCGGCCAGCATGAAGCAGGCCCTGATCGCCTCGGCTCGCAGGCTGCCTGGCGTCAACATGTTTGAGCAGGGCCACGGCAAACTCGATTTACTCAGAGCATATCAGATCCTTAACAGCTACAAACCGCAAGCCAGCTTGAGTCCAAGCTACATTGATCTGACCGAGTGCCCGTACATGTGGCCCTACTGCTCTCAGCCCATTTACTACGGTGGCATGCCAACAATCGTCAACGTGACCATTCTTAATGGTATGGGCGTGACAGGACGGATTGTAGAGAAGCCCATCTGGCAGCCCTATCTCCCTCAGAATGGAGATTATGTGGATGTGGCGGTGTCTTACTCACCTGTGCTCTGGCCCTGGGCCGGGTACCTGGCTGTTTCTATATCTGTGGCCAAAAAAGCAGCATCTTGGGAAGGCATCGCTCAGGGTCATGTCATGGTTACAGTGGCCTCCCCTGCAGAAAATGACTCTGCAATAGGTGGTGAAATGACCTCCACAGTGAAGCTGCCAGTGAAAGTGAAGATTGTCCCCACTCCTCCACGCAGTAAGAGGATTCTATGGGATCAGTACCACAACCTGCGCTACCCACCCGGATACTTCCCCCGAGATAACCTGCGCATGAAGAACGATCCACTTGACTGgAATGGTGACCATATTCACACTAACTTCAGAGACATGTATCAGCACCTTCGCAGCATGGGCTACTTTGTTGAGGTCTTGGGTGCACCAATCACTTGCTTTGATGCCAGTCAATATGGAACGTTGCTGATGGTGGACAGCGAAGAGGAGTATTTTCCAGAAGAGATCACCAAGTTGAGGAGAGACATTGATAATGGCCTGTCTCTCATCGTTTTCAGTGACTGGTACAACACATCAGTCATGAGAAAAGTCAAGTTCTATGATGAAAACACCAGACAGTGGTGGATGCCAGACACAGGGGGTGCTAATGTGCCAGCCTTGAATGACCTGATCTCAGTTTGGGGAATGGCCTTCAGTGATGGCCTATATGAGGGAGACTTTACCTTAGCAGATCATGACATGTATTATGCATCTGGGTGCAGCATTGCTCGTTTTCCCGAGGATGGGATTGTTATCGCTCAGACACTGAAGGATCAAGGTCTGGAGGTCTTGAAGCAAGAGACTGCAGTGGTGGAAAATGTGCCTGTGCTTGGACTGTACCAAACACCCTCTGATGGGGGAGGCCGCATTGCACTCTATGGAGATTCCAACTGCATTGATGACAGTCACAGGCAGAAAGACTGTTTTTGGCTGCTGGATGCTCTGCTTCAGTACACTTCCTACAGCATGACTCCGCCCAGCCTCACCCACTCAAAAAACAGATTGGTCCCTCCTACAGGCACAGACAGGCCATTACCACAGAGATTAGAAGGGAATCACTTGTATCGTTACTCCAAAGTGCTGGAGGCTCATCTGGGTGACCCTAAACCTCGTCCTCTTCCTGCATGCCCTCATCTGTCTTGGGCCAAACCTCAGCCTCTAAATGAGACTGCTCCTAGCAATCTTTGGAAACACCAGAAACTTCTGTCAGTGGACATGGACAAGGTTGTTTTGCCTAATGTCAGGGCATATCGGCCTCAGGTTCGACCCCTGTCTCCTGGGGAAAGTGGAGCTTGGGACATTCCTGGAGGAATAATGCCTGGACGATATAATCAAGAGGTGGGACAGACCATCCCGATGTTTGCCTTTCTTGGTGCCATGGTTGTGCTTTCCTTCTTTGTAGTGCAATTGACCAAAGCTAAGAGCAAACCCAAACGCAGGAAACCCCGAGTGAAACGGCCACTTTaccttcaacaacaacaacaacaacagcaaaccCCTCACTCAGGCAAAAACCCCACTGTATGATCGGCCACATCTGGACAAACCTAATAGGGAAGGGTCTTccctgaggtgtgtgtgtgatgccGTAACCCCGTGGAAATGAGATTGTTGGACTCTTGTTGAGAAAAACCAGCAGCCACCTGAACTCAAACGAGGGCTTTGCTTGGAGATCGGTGATTCTCTCTTGTCTTTATTCAACACATGCCTTTCAATTCAGTGACCAAATGGAGgaatgtttccttttttaatttattgatgaaATGATTAATTGACTATTGACCTTTTGCTTTAATACTGCAAATTCGGACAGACACCAGCCCTTCAGTTTCCTCAATCAACTGGACTGGTTTCCTACACGTCCTCATTTTTGTATTCCGTCAGACTGTTTTTATAAAAGCGTTGTGTGCTTGCGTCTTTTGTAAATAGCCCATCATGATTTCACTGTTGTTGGTGTGGAATTatcaatgttttaaatatatcttATCCGATATAAAGCAAGAAAA

Function


symbol description
mbtps1 Predicted to enable serine-type endopeptidase activity. Acts upstream of or within cartilage development; lipid metabolic process; and liver development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including axial chorda mesoderm; axis; margin; pleuroperitoneal region; and tail bud. Human ortholog(s) of this gene implicated in spondyloepiphyseal dysplasia Kondo-Fu type. Orthologous to human MBTPS1 (membrane bound transcription factor peptidase, site 1).

GO:

id name namespace
GO:0006629 lipid metabolic process biological_process
GO:0051216 cartilage development biological_process
GO:0006508 proteolysis biological_process
GO:0001889 liver development biological_process
GO:0005794 Golgi apparatus cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004175 endopeptidase activity molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function

KEGG:

id description
ko04141 Protein processing in endoplasmic reticulum
ko01002 Peptidases and inhibitors
ko03110 Chaperones and folding catalysts

ZFIN:

id description
ZDB-GENE-030131-4909 Predicted to enable serine-type endopeptidase activity. Acts upstream of or within cartilage development; lipid metabolic process; and liver development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including axial chorda mesoderm; axis; margin; pleuroperitoneal region; and tail bud. Human ortholog(s) of this gene implicated in spondyloepiphyseal dysplasia Kondo-Fu type. Orthologous to human MBTPS1 (membrane bound transcription factor peptidase, site 1).

Ensembl:

ensembl_id ENSDARG00000014634

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00026482 True 4150 mRNA 0.48 23 21645309 21685055

Neighbor


gene id symbol gene type direction distance location
XLOC_013408 slc38a8a coding downstream 4920 21622414 ~ 21640389 (-)
XLOC_013407 pnp6 coding downstream 373936 21257261 ~ 21271373 (-)
XLOC_013406 calb2a coding downstream 426458 21198762 ~ 21218851 (-)
XLOC_013405 got2a coding downstream 456541 21178721 ~ 21188768 (-)
XLOC_013404 si:dkey-12e7.4 coding downstream 467635 21171465 ~ 21177674 (-)
XLOC_013410 fan1 coding upstream 1060 21686115 ~ 21725805 (-)
XLOC_013411 BX548157.1 coding upstream 27241 21712296 ~ 21720051 (-)
XLOC_013412 pskh1 coding upstream 43139 21728194 ~ 21748966 (-)
XLOC_013413 nrn1la coding upstream 97019 21782074 ~ 21910991 (-)
XLOC_013414 nutf2 coding upstream 228630 21913685 ~ 21929451 (-)
XLOC_013384 BX323829.1 misc downstream 2103078 19542102 ~ 19542231 (-)
XLOC_013398 BX470160.1 non-coding downstream 798996 20846190 ~ 20846313 (-)
XLOC_013395 BX470130.1 non-coding downstream 1011386 20633789 ~ 20633923 (-)
XLOC_013388 NA non-coding downstream 1325436 20285665 ~ 20319873 (-)
XLOC_013387 NA non-coding downstream 1496212 20140072 ~ 20149097 (-)
XLOC_013386 NA non-coding downstream 1761015 19883591 ~ 19884294 (-)
XLOC_013417 CT573204.2 non-coding upstream 398717 22083772 ~ 22083886 (-)
XLOC_013420 CR933017.1 non-coding upstream 865540 22550595 ~ 22552314 (-)
XLOC_013426 BX088710.1 non-coding upstream 1054677 22739732 ~ 22753637 (-)
XLOC_013427 BX663522.1 non-coding upstream 1174424 22859479 ~ 22862467 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_03241607_03258684 MBTPS1 coding CI01000013 null 3241607 ~ 3259203 (+)
bowfin (Amia calva) AMCG00020381 mbtps1,LOC107596929 coding CM030127.1 CM030127.1 17559537 ~ 17584315 (+)