XLOC_013496 (gas8)



Basic Information


Item Value
gene id XLOC_013496
gene name gas8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 31033122 ~ 31051847 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00026612
CTACAAAGAAGAAGACAATGTTTTTACCCTTTTGGTTCACCAGTCCCATGTTGCTAGGAAACCGTTGTGAAACAATTCAATGCATTTTCATTTGTGGCGAAAATTACGCGTTCCCAAATAATGCCACCAAAAAGAAAATCGTCGCCGAAGGGCAAAACTCCAACAGTAGTGGACGGCTTGTCCACAGAGGAGATGTCAAAAGAGCAGTTGGAGGAGCACATAATGCGTCTCCGAGAGGAGCTGGACAGGGAGAGAGAAGAACGCAACTATTTCCAGCTAGAGAGGGACAAAATTCACACTTTCTGGGAAATTACACGACGACATCTCGAAGAGAATAAGTGTGAGCTGAGAAACAGAGAGCGTGAATTGGAGGAAGTAGAGGAACGCCACCAAGTGGAAATTAAGGTTTATAAACAGAAGGTGAAGCACTTGCTGTACGAACAGCAGAACATGCTGTCTGAGCTAAAGGCTGAAAGCATCATCAGCACCAAACTGCTGCAGGATGAGCATGCTGATTTGGAGAAGGAGCAGTGGAAGGATATGCGCAGTTTGAAACTTGAGTTGAAACAACAAGAGCTGTCCAGTGAAAATGTGTTAAAGAGAATTCATCTAAAACATGATGAGGAAACTACTGATTTGAGAAATGATTTTGCCAGACAAGTACAAGAAATTGGGTCCAAATATGAGAAAAGGATGCAGAAACTGCGTCAGGAGGAAGAACTGAGACGCAAGACAGAGATTCATGAGATTGAGGAGCGGAAGAACACCCACATTAACATGCTGATGAAGAACCATGAAAAAGCTTTCAGAGACATCAGAAACTACTTCAGTGACATAGTCTACAAGAATCTGGACCTTATCACTTCACTCAAGGAAGAGTTAAAGGAAATGAAAAAGAACGAGGAGAAGAGAAATAAAGAGATGGCGGAAGTACTTGAGCAGAATAAGGAGCTTAAAGAGTCTTCACAGAAGGCAAAAGAACAAGTTGCTGAGCTTCAGAAACAGCTTGCCAATTATGAGAAGGACAAGAGCATTTTAACTCGGTCAAGAGCTCGTCTCAAAATGTCTGACAGAGAAATGAAAGAGCTTAAGTGGGAGCTTGAAGTGTTGGAGCAGAGATTTTCTAAGGTTCAACTGGAGCGGGACGAATTGTACATGAAGTTCACTAAAGCCATTCTAGAGGTTCAACAGAAGAGTGGTTTTAAAAACTTGCTGCTTGAGTGCAAATTGAACACACTCAATGACACGCTTGAGAAGAAGGAAGCCCAGCTCAGTGAGGTGCTGTCTGCTTCCAACCTGGACCCCACCACCCTCAGTGTGGTCACCCATAAATTGGAGGAAGTTTTGGAGTCCAAAAACCATACTATTAAAGACTTACAGTATGAAGTTGCACGAGTTTGCAAGGCCCATAATGACTTGCTAAAGACTTCTGAAGCAAAGCTGCGAGCATTTGGTATTCCTGTGGAAGAGCTCTGCTTCGAGCCACTTAAAAGCAATGGACAGAGTGTTGGCCAGGGCCCTGCTATGTTTGTTTCTTCTTCAAATtagcattttgaaaaaaaaaataataataataaacaaataatcaaa
>TCONS_00026613
AAGCCAAAATGTGTTATAATGTGTTAACGTTAATTGCAAATGGTAACTTAGTTAATCTACCAAATCTAACGTATTTCTTATCGTTTATTGACTAGCAACATTACATTCTAACGATACTGTGCTGTTTGTAATAGATGCAGAGATCTCATCTTGATCGAATGTAACGTTAGCCTGTTTAGCGTTAACTTATCACTTCATATTTCAGCCACCAAAAAGAAAATCGTCGCCGAAGGGCAAAACTCCAACAGTAGTGGACGGCTTGTCCACAGAGGAGATGTCAAAAGAGCAGTTGGAGGAGCACATAATGCGTCTCCGAGAGGAGCTGGACAGGGAGAGAGAAGAACGCAACTATTTCCAGCTAGAGAGGGACAAAATTCACACTTTCTGGGAAATTACACGACGACATCTCG

Function


symbol description
gas8 Predicted to enable microtubule binding activity. Involved in cilium movement involved in otolith formation and otolith tethering. Acts upstream of or within muscle cell development and positive regulation of smoothened signaling pathway. Predicted to be located in ciliary basal body and cytoplasm. Predicted to be active in Golgi apparatus and microtubule. Is expressed in neural tube; otic placode; otic vesicle; and pronephric duct. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Orthologous to human GAS8 (growth arrest specific 8).

GO:

id name namespace
GO:0003355 cilium movement involved in otolith formation biological_process
GO:0055001 muscle cell development biological_process
GO:0035082 axoneme assembly biological_process
GO:0035889 otolith tethering biological_process
GO:0048870 cell motility biological_process
GO:0045880 positive regulation of smoothened signaling pathway biological_process
GO:0034613 cellular protein localization biological_process
GO:1903566 positive regulation of protein localization to cilium biological_process
GO:0030317 flagellated sperm motility biological_process
GO:0031514 motile cilium cellular_component
GO:0042995 cell projection cellular_component
GO:0036064 ciliary basal body cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005874 microtubule cellular_component
GO:0005929 cilium cellular_component
GO:0005737 cytoplasm cellular_component
GO:0008017 microtubule binding molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-030131-1980 Predicted to enable microtubule binding activity. Involved in cilium movement involved in otolith formation and otolith tethering. Acts upstream of or within muscle cell development and positive regulation of smoothened signaling pathway. Predicted to be located in ciliary basal body and cytoplasm. Predicted to be active in Golgi apparatus and microtubule. Is expressed in neural tube; otic placode; otic vesicle; and pronephric duct. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Orthologous to human GAS8 (growth arrest specific 8).

Ensembl:

ensembl_id ENSDARG00000101431

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00026612 False 1590 mRNA 0.42 11 31033122 31051847
TCONS_00026613 True 410 lncRNA 0.41 2 31049489 31051597

Neighbor


gene id symbol gene type direction distance location
XLOC_013495 NA coding downstream 72053 30960172 ~ 30961069 (-)
XLOC_013494 FO834814.1 coding downstream 177587 30854496 ~ 30855535 (-)
XLOC_013493 NA coding downstream 279699 30752484 ~ 30753423 (-)
XLOC_013492 emc8 coding downstream 528470 30500690 ~ 30504652 (-)
XLOC_013491 gins2 coding downstream 533633 30481030 ~ 30499489 (-)
XLOC_013497 pdcd5 coding upstream 38110 31089957 ~ 31105391 (-)
XLOC_013498 mc1r coding upstream 174441 31226288 ~ 31227615 (-)
XLOC_013499 CU570893.1 coding upstream 247229 31299076 ~ 31423569 (-)
XLOC_013500 NA coding upstream 672259 31724106 ~ 31724812 (-)
XLOC_013501 NA coding upstream 680776 31732623 ~ 31737816 (-)
XLOC_013384 BX323829.1 misc downstream 11490891 19542102 ~ 19542231 (-)
XLOC_013487 BX908800.1 non-coding downstream 1114017 29918062 ~ 29919105 (-)
XLOC_013485 NA non-coding downstream 1630106 29397940 ~ 29403016 (-)
XLOC_013504 BX908386.2 non-coding upstream 953211 32005058 ~ 32009056 (-)
XLOC_013505 NA non-coding upstream 987654 32039501 ~ 32042362 (-)
XLOC_013507 BX649622.1 non-coding upstream 1094861 32146708 ~ 32147630 (-)

Expression



Co-expression Network