Item | Value |
---|---|
gene id | XLOC_013535 |
gene name | ryr1b |
gene type | coding |
species | zebrafish (Danio rerio) |
category of species | model fish |
Item | Value |
---|---|
chromosome id | NC_007129.7 |
NCBI id | CM002902.2 |
chromosome length | 51023478 |
location | 35491473 ~ 35736591 (-) |
genome version | GRCz11_2017_zebrafish_Genome |
symbol | description |
---|---|
ryr1b | Enables ryanodine-sensitive calcium-release channel activity. Involved in skeletal muscle fiber development and smoothened signaling pathway. Acts upstream of or within cellular response to oxidative stress; larval locomotory behavior; and twitch skeletal muscle contraction. Predicted to be located in membrane and sarcoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be part of calcium channel complex. Predicted to be active in several cellular components, including Z disc; endoplasmic reticulum; and sarcolemma. Is expressed in adaxial cell; heart; skeletal muscle cell; trunk; and trunk musculature. Human ortholog(s) of this gene implicated in central core disease; malignant hyperthermia; and multiminicore disease. Orthologous to human RYR1 (ryanodine receptor 1). |
id | name | namespace |
---|---|---|
GO:0051209 | release of sequestered calcium ion into cytosol | biological_process |
GO:0070588 | calcium ion transmembrane transport | biological_process |
GO:0055085 | transmembrane transport | biological_process |
GO:0034599 | cellular response to oxidative stress | biological_process |
GO:0003009 | skeletal muscle contraction | biological_process |
GO:0006811 | ion transport | biological_process |
GO:0006816 | calcium ion transport | biological_process |
GO:0008345 | larval locomotory behavior | biological_process |
GO:0031443 | fast-twitch skeletal muscle fiber contraction | biological_process |
GO:0031444 | slow-twitch skeletal muscle fiber contraction | biological_process |
GO:0006874 | cellular calcium ion homeostasis | biological_process |
GO:0042383 | sarcolemma | cellular_component |
GO:0034704 | calcium channel complex | cellular_component |
GO:0005790 | smooth endoplasmic reticulum | cellular_component |
GO:0005886 | plasma membrane | cellular_component |
GO:0033017 | sarcoplasmic reticulum membrane | cellular_component |
GO:0030018 | Z disc | cellular_component |
GO:0016020 | membrane | cellular_component |
GO:0016021 | integral component of membrane | cellular_component |
GO:0030659 | cytoplasmic vesicle membrane | cellular_component |
GO:0048763 | calcium-induced calcium release activity | molecular_function |
GO:0005509 | calcium ion binding | molecular_function |
GO:0005515 | protein binding | molecular_function |
GO:0005216 | ion channel activity | molecular_function |
GO:0005219 | ryanodine-sensitive calcium-release channel activity | molecular_function |
GO:0005262 | calcium channel activity | molecular_function |
id | description |
---|---|
ZDB-GENE-070705-417 | Enables ryanodine-sensitive calcium-release channel activity. Involved in skeletal muscle fiber development and smoothened signaling pathway. Acts upstream of or within cellular response to oxidative stress; larval locomotory behavior; and twitch skeletal muscle contraction. Predicted to be located in membrane and sarcoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be part of calcium channel complex. Predicted to be active in several cellular components, including Z disc; endoplasmic reticulum; and sarcolemma. Is expressed in adaxial cell; heart; skeletal muscle cell; trunk; and trunk musculature. Human ortholog(s) of this gene implicated in central core disease; malignant hyperthermia; and multiminicore disease. Orthologous to human RYR1 (ryanodine receptor 1). |
ensembl_id | ENSDARG00000023797 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
TCONS_00026655 | False | 15240 | mRNA | 0.49 | 104 | 35491473 | 35736591 |
TCONS_00026982 | False | 581 | lncRNA | 0.49 | 4 | 35544276 | 35548058 |
TCONS_00026983 | False | 915 | lncRNA | 0.50 | 5 | 35561269 | 35565396 |
TCONS_00026984 | True | 589 | lncRNA | 0.50 | 3 | 35562009 | 35565285 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
XLOC_013534 | itpkcb | coding | downstream | 31477 | 35429333 ~ 35459996 (-) |
XLOC_013533 | snrpa | coding | downstream | 83683 | 35402759 ~ 35407790 (-) |
XLOC_013532 | CABZ01040999.1 | coding | downstream | 100738 | 35375229 ~ 35390735 (-) |
XLOC_013531 | NA | coding | downstream | 237451 | 35251298 ~ 35254022 (-) |
XLOC_013530 | NA | coding | downstream | 603401 | 34886240 ~ 34888072 (-) |
XLOC_013537 | hnrnpul1 | coding | upstream | 70997 | 35807588 ~ 35837673 (-) |
XLOC_013538 | opa3 | coding | upstream | 102161 | 35838752 ~ 35842554 (-) |
XLOC_013539 | exosc5 | coding | upstream | 323704 | 36060295 ~ 36066087 (-) |
XLOC_013540 | b3gat1a | coding | upstream | 369339 | 36105930 ~ 36135799 (-) |
XLOC_013541 | BX950224.1 | coding | upstream | 718716 | 36455307 ~ 36465466 (-) |
XLOC_013384 | BX323829.1 | misc | downstream | 15949242 | 19542102 ~ 19542231 (-) |
XLOC_013529 | NA | non-coding | downstream | 936856 | 34551528 ~ 34554617 (-) |
XLOC_013527 | NA | non-coding | downstream | 1263574 | 34227352 ~ 34227899 (-) |
XLOC_013522 | NA | non-coding | downstream | 1541614 | 33946342 ~ 33949859 (-) |
XLOC_013542 | NA | non-coding | upstream | 978048 | 36714639 ~ 36733902 (-) |
XLOC_013543 | NA | non-coding | upstream | 1112558 | 36849149 ~ 36887469 (-) |
XLOC_013544 | NA | non-coding | upstream | 1165430 | 36902021 ~ 36918987 (-) |
XLOC_013550 | AL627088.1 | non-coding | upstream | 1673232 | 37409823 ~ 37415445 (-) |