CI01000340_03379959_03401892 (GFI1AB, GFI1)


Basic Information

Item Value
gene id CI01000340_03379959_03401892
gene name GFI1AB, GFI1
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000340
NCBI id null
chromosome length 19571558
location 3379286 ~ 3401952 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000340_03379959_03401892.mRNA
AGATTGCCTGATCTTCACTAATGACTGAGGACATCGAAAGAAGGAACCAGAGGAGACACAATGCCTAGGTCTTTCTTAGTGAAGAGCAAAAAAGCGCACAGCTACCACCAGCCACGATCTTTGGAAGATGACTACAACAGACTTGATACTATTTTAGCTCATATATGTGCAGATTTTCGGTGGCACACTACAATCAACCATTACGTTGTACCATATGTTGTAAGATTCATATTTAGCCTAATACAAGCTGCGGTTTTGACTGGGGGAAAAATCATTACAGAAAACAAAACTTCAGACGAGTCAGAGTGCTGTACGGATGCCCTGACAGGCGACACGACTGGTGCTTGTTCACCGGACTCTCACCTGGTGGATCAAGCTGAGTCTCCTCTCAGCTGTGAGGGAAGTGTGTGCGACCGCTCGTCAGATTACGAAGACCTTTGGCGACCTCCATCACCATCAGCATCACCGGAGTCAGCAAAATCCTTTTCACCCTCCGTTGAGGAAACACAGCCTTTCGCCGTCCCTTTCAGGCCTTACGCGTGGAGCAGGTACTCAGGATGTGAAATCAGACAGCTGGTACAGCATACTCTCAATCATCACCATTCTCTCGAGCGGCCTACACCACCAGCCTATTACAATGACCGCGTGGCCGAGCCCTCTCTTTTCACTGAACGAGGATCTGGCGCAGGTATTTACAGCTCCACTGCCACCCTATTCGAGCGCGCCACTGCCTCTGGATTTTATGATGACAGCAGCATACTGGGAAAAGGAACTGAGATAAAATCCAGCTCTGATGTTATGTGTAGTCGTCTCCTGCTCAATGGCGCATACAAATGTATAAAATGCAGCAAGGTGTTTTCTACACCACATGGCTTGGAAGTTCACGTCCGGAGGTCGCATAGTGGAACAAGACCTTTTGCTTGTGACATCTGTGGGAAAACGTTCGGACACGCGGTCAGTCTGGAACAACACAGAGCTGTTCACTCACAGGAGAGAAGTTTCGACTGTAAAATCTGTGGGAAAAGTTTTAAAAGATCATCCACTCTGTCCACTCATCTTCTCATACACTCCGATACAAGACCCTACCCATGCCAGTACTGTGGAAAGCGATTTCACCAGAAATCAGATATGAAGAAACACACATTCATCCACACAGGGGAAAAACCACACAAATGCCAGAGTAGGCGACTAATAGCGTTTACATTAGTTGTGGAGCTGTTTATGCTTTGTGAGATTTGCCTACGAGTCAGCAGCAGGCCAGCAGGTCTGGCAGCTTTCATGTCTAAAATGGCCCGAGGATATAACGTCAACTTATCTGGTTCTGGCACAGTGAAGCCTGAAAGCTTTTCCATTAGTTATCTCGCAGTGGGGCCCACCAACCCCTGCACAGCACGCAGTCGGCCTAGTCAGCTGCTGAAAGATCAAGCAGAGTACAGTCAGCTGCCTCTTCTGCCATTGGGGGTTGCCTACAGAGATGAAGGCACAGAGTACCCAAGCACACAAGTGGACTCTGTCGTGCTGGTGAGCATGGTATTGATCAAAGGCAGACGGGTTGTCTCTCCTTCAGAAAAGGGGCCAGCGTTATCCTTGTCAATTAAGGTTCACACACTGGCATTCGAGAGAGCTCCATCTTGTCCCATCTATTTTAGATTGCTTCTTAATCCTATTAGCAGACACTCAGCTGCAGTGCTTACTAAGAGGTTTACAAGGGTACCCTGTCAGATTGCCTCTTGCTCGGTTCTTTTCAAACACTCTGACCTCCATTATAAACCTAGCTACCCTATTCTTTTGTGTGGAAATTTTATTGCAGCTAGATGTCATTCAGATCTTGAACAGAAAAGCCTCTGTTATAATCCTGACCTTGAAGAGTTACTTATATGGACTATTTTTGAAAAGACCAGCTCTGAAAATGGCAGTGAATCAAATAGAGGATGTAATTCAAAGATGGAGATAGAGGATTTGACAATGACTCTGTTTCAGAGAACAACTGAAGACTTTAAACCAGAGGACCATGAGCTCTTTCTGAATGCTGGTCGCACCTGCATTGCCCAAGGTGACAGCAGTGAACTACTGGACTTCATAAAAGAGGAGGCCAATCAGCACATAGTGAGGTCTATGGGCAGTGGCCTACTACCTGCACTGGTGAATGAAGTGCTGAGAAAGGACCGGAGTCCTGCCCACTGTCAGGTTATCCTCAATGAACTTGTACAGATCTGCAGTGTGCAAGAACTCCTTGATATTTTACTTGAGCAAGTGGAGGAGACTGATCCAAATGCCATTGCAGACACCATCATTGTTCTCATGCCTCTTATTCAGTCAGTGTTGTTGAGAATGAGTGAGTCAAAAGCCCCTGGATTGGCTTTGGCGCTTGATTCTTTGCAGAAACAAATTTCAAGGCTGCCTGTACCTTACTCACACAAACAGGAACAGGAAGATGTGTATGGGCTCTGCCGATGCTGCACTGCAGTACTGACCTTTGTACAACCCTTTGTACAGGAAGCCGAGAATCAAGACACAAATTCAGTGGCCACCAAACTAAGAGCTGCTCTTCTAACGTTTTGCATGAAGAGTCTAAGGGAACCTCTCCTCCAAGTTCAGCTGGACAGAGAGGTAAACACGAAAGAAATTTCACCCCTGAGGAATTTTGCCACAGAAATCATGGCAATCTTAGCAGTGAGCCAAGAGTCTCTGCCAAAAATACTGTTCTACCAGCCTTTGAGGGGAAAAGAAGACACTATACTGGAAAAAGATGCTTATTATCCAAATGAATCAAGAGCTTGCATGGCTTACTTGCTGTTTGTCCAGCTTATTGCCATAGAAGTGTTTCCTGCAGTTTTTAGAAAGGATGAATCGTGGATTTTGAAAGGACTGAACTTAATTAAAATTATGATTGACTGTCCTATCCAGCATTTGTCAGCCTACCAGGATGGCTGGTTTGAGGGGACATGGCTCATCTCACTGCTCAGAGACACTATCACTCTCCCACAGGGCCATGAAACTGACTTGCTACATGGGATGGACAGGGTCATGGAGTCTCTGAATCTTCTGCGGTATTTATTGATAAAGGAAAGAGAAATTTCCACTGGAATATGGATAGACCTGTGCCACATTGCAGAAAGTTACACAAAATTATTACGAGTATGTCTAAGCATGTCAAAATCATACTATGGAAAAGAGCTAAAAAGACTTAGAGAGGACAAAAAGATCAAGGCTAAAGAATTTAAGGAGGCCTCTGGGAAGAGATCAGTTCAGAGCTTGATTGTGAAAACAGAGACACTAGGCAGCATGCCACGTGAGGCACAAGATAAGGTCTTGCAGTGCGCACTGGTCACATATGACTTAATGGAAAGCCTTGTGGTTCGTATAGAGGACATCATTGAGGAGGGTCAAAAATGAACAAGTGGGCACAATTACTGTGGTCTGAACTGAATAATGTATTTATTTATTTACATTCCCTGTACCATGCTGCATTTTGCATGTGAGAGATACAATATTGATATTTTCAATACTGTATTCATACTCTTCAGTCTTTTTCAGCACAAAAAAGGTGGCGATTTTTCCTCTGACAAAGTTTATACTTTGTTTTTAATGAAGAATTGCTATTATGAAAGAAAAAAAAAGTTTTACAAGAATATGAACAGTATGAATGGCAATTAACAGTTTTTACACAAGTTACTTTGAAACAATACTGACATCTGCTGTTAAAAAGAAGTATAGCAAAACATTAAGAAAATGAATGGACAGGAACATAAATATCACTACAACTCTCTCTCTTGAAGCATCCCCCAAACTGGGCTATGATCAATGATTTGAGCACAAGCCAAAGACATCTGATCTCTCAAATTCTCCACATTGGGTTTACTTGTGGCCTGGAATATAAAGGCCATTAAACTTTTTGCAGACACTTTGCTAATATACTTCTCATAAACCGAATTTTAGTATAAATAATTTTATAGTAAGCACAGTCCTTGACGTTAAATTCAAATTAACATTAAAACCATAACATAATTTACCTCTAGACAGCATTCATTGTAAAATGAAAACATTACTAAAAAATTATAAGAATAAA

Function

symbol description
gfi1ab Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within peripheral nervous system development. Is expressed in anterior lateral mesoderm; nervous system; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in acute myeloid leukemia and severe congenital neutropenia 2. Orthologous to human GFI1 (growth factor independent 1 transcriptional repressor).
gfi1 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to lipopolysaccharide; negative regulation of cellular biosynthetic process; and regulation of signal transduction. Located in nuclear body and nuclear matrix. Part of transcription repressor complex. Implicated in acute myeloid leukemia and severe congenital neutropenia 2. Biomarker of leukemia and myelodysplastic syndrome.

GO:

id name namespace
GO:0050767 regulation of neurogenesis biological_process

KEGG:

id description
K09223 GFI1; growth factor independent 1

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000340_03379959_03401892.mRNA True 4069 mRNA 0.43 25 3379286 3401952

Neighbor

gene id symbol gene type direction distance location
CI01000340_03342324_03363204 TOMM70, TOMM70A coding downstream 15667 3342301 ~ 3363619 (-)
CI01000340_02936853_02939837 BCL6A, BCL6 coding downstream 439449 2935637 ~ 2939837 (-)
CI01000340_02567081_02567521 NA coding downstream 811643 2566737 ~ 2567643 (-)
CI01000340_02341068_02348409 NA coding downstream 1030809 2340503 ~ 2348477 (-)
CI01000340_02333476_02337529 AGXTA coding downstream 1041757 2333102 ~ 2337529 (-)
CI01000340_03403238_03403692 NA coding upstream 1271 3403223 ~ 3403692 (-)
CI01000340_03406706_03449487 EVI5 coding upstream 4522 3406474 ~ 3449487 (-)
CI01000340_03474617_03478517 FAM69AB, FAM69A coding upstream 72008 3473960 ~ 3478517 (-)
CI01000340_03500913_03512175 ZBTB11 coding upstream 98379 3500331 ~ 3512695 (-)
CI01000340_03528645_03535760 DPT coding upstream 126348 3528300 ~ 3535960 (-)
G488627 NA non-coding downstream 78067 3300988 ~ 3301219 (-)
G488540 NA non-coding downstream 163583 3215451 ~ 3215703 (-)
G488534 NA non-coding downstream 167662 3211391 ~ 3211624 (-)
G488507 NA non-coding downstream 193292 3165332 ~ 3185994 (-)
G488395 NA non-coding downstream 334344 3021147 ~ 3044942 (-)
G488543 NA non-coding upstream 63360 3465312 ~ 3473302 (-)
G488643 NA non-coding upstream 112513 3514465 ~ 3514967 (-)
G488645 NA non-coding upstream 115553 3517505 ~ 3517756 (-)
G488649 NA non-coding upstream 119420 3521372 ~ 3521596 (-)
G488651 NA non-coding upstream 123396 3525348 ~ 3525600 (-)
G487884 NA other downstream 1477014 1895801 ~ 1902272 (-)
CI01000340_00787534_00791061 NA other downstream 2587877 786551 ~ 791409 (-)
G485786 NA other downstream 3053570 325334 ~ 325716 (-)
CI01000340_00062787_00080635 NA other downstream 3297191 62780 ~ 82095 (-)
G488782 NA other upstream 603853 4005805 ~ 4006448 (-)
G488862 NA other upstream 1105244 4507196 ~ 4518120 (-)
CI01000340_04598932_04627160 NA other upstream 1198268 4598714 ~ 4627447 (-)
CI01000340_05321995_05329778 ATG4C other upstream 1918801 5320753 ~ 5330215 (-)
CI01000340_06095704_06194498 MAST2 other upstream 2781338 6095704 ~ 6194501 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_032899 gfi1ab coding NC_007117.7 CM002890.2 29004062 ~ 29007493 (-)
rainbow trout (Oncorhynchus mykiss) gfi1ab LOC106584164 misc NC_050570.1 CM025857.1 31784332 ~ 31796285 (-)