XLOC_013561 (leo1)


Basic Information

Item Value
gene id XLOC_013561
gene name leo1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 39292911 ~ 39321484 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00026692
TATTTTTACAGCCTGTGAAAATGGCGGATATGGACGAACTGTTCGGGAGCGATGGCGATAGCGACAATGAGCAACGAGATTCCGGCTCTGGTTCTGGCTCTGATTCGGATCATGAGAGACCAAGATCTGCCAGCAACGCTTCTGGAAGCGAGAGTGCTCAGAGTGACCgagatcatgatgatgatgaagatgaagatggcGGAAAGCCTAGCAATAAAGAGCTGTTTGGAGACGACAGTGAAGATGAGCACGGCAGCCAGCACAGCGGGAGCCAGCACAGCGGCAGCCGGCACAGCGGCAGCCGGCACAGCGGCAGCAGGCACAGTGGCAGTAGGCACAGTGGCAGCCAGCACAGCGGGAGCCAATCAGAGCGATCGGGCAACCAATCAGACGCCACCATGCACTCTGACAATGAACACAGCATGTCTGAGGCCCATCGTGGTGAGcaggatgatgaggatgatgatgacagAGGCCACAGGTCAGACGTAGGCAGTCCAGCCTCAGGAGCAGGAAGCCGCAGGTCGGACAGAGGAAGTGGAAGTCCAGGGTCAGAGGCGGGAAGTCCACGCTCAGAAGCTGGAAGTGGTCATTCGGATCCTGGAACCCCACATACAGATGGAGAGGGGTCAGGGAAAGATGCCCATTCTGGAGATGAGAAGTGGGGTGGAGATGGAAAAAGTGACCAGTCGGAGGACGAGGACAAACAGCAGAACTCTGATGATGAGAGGGAGCGATCTGATGAAGAAGGGGAGAGGCAGAAATCAGAGTCGATTAAGGGCAGTGACAGCGAGGATGATTTCACAcgcaagaaaaagaaaaagattgcTTCGGACTCGGACTCAGACTCTGATGCTGAAACACAGGGTGgtAAGAAGCCTGCAGCAAATGATCTTTTTGGGGAGGCAGATGATATTTCGTCAGACAGCGATGCAGAGAAACCTCTCACACCTGGCCAACCATTGGATGCAGATGACGGAATGGAGGGAGATCAGCCTGAGGAAGAGCCAGCTCCAGAGACGAGGATTGAAGTGGAGATACCTAAAGTCAGCACAGACCTGGGCAGCGATCTCTACTTCGTCAAATTACCCAACTTTCTCAGTGTGGAGCCCAGGCCGTTCGACCCTCAGTACTATGAGGATGAGTTTGAGGATGAGGAGATGTTAGACGAGGAAGGAAGAACTCGTCTAAAGCTAAAGGTGGAGAACACCATCAGGTGGCGCTCTCGACGGGATGAGGAGGGCAATGAAGTCAAGGAGAGCAATGCTAGGATTGTTAAATGGTCTGACGGCAGCATGTCTCTGCACCTGGGGAACGAAGTGTTTGATGTGTATAAAGCTCCACTGCAGGGTGACCACAATCACCTGTTCATCCGCCAGGGCACAGGACTGCAGGGTCAGGCTGTGTTCAAGACCAAACTCACCTTCAGACCTCACTCCACAGACAGCGCCACACACAGGAAGATGACGCTCTCTCTTGCCGACCGCTGTTCAAAGACACAGAAGATCCGAATTTTGCCCATGGCTGGCAGAGACCCAGAGTCCCAGAGAAATGAGATGATCAAGAAAGAAGAGGAGAGGTTACGTGCGTCCATCAGGCGCGAGTCCCAGCAGAGGCGCATGAGAGAGAAACAGCATCAACGAGGTCTGAACGCCGGCTACCTGGAGCCTGACCGCTACGATGAGGACGAAGAGGGTGAAGAGTCCATTAGCCTGGCTGCAATCAAGAGCAAATATAAGGGTGGAGGAGGTCTAAGGGAGGAACGAGCCAGGATCTATTCGTCAGACAGCGATGAAGGTTCTGATGAAGACAAGGCCCAGCGACTGATGAAGGCCAAGAGACTGGACAGCGATGAGGAGGGAGAGAACTCTGGAAAGAGGAAGGCAGAGGAAGATGAGGAATCTGCTTCAAAGAAGCCCAAAAAGTATGTCATTAGTGATGAAGAAGACGAGGACGGAGATGGAGAACGCGATGGAGACCGAGAGAGAGGCGGGGATATGGATGGAGACGGAGATGGAGATATGGAAGGAGATGGAGATGTGGACAGAGACGGAGATATGGATGGAGATGGAGAAGGCGATGGAGAGGGAGACGGAGAGGAAGacgagtaattttttttttcttaattttttttttttttacattaatgttttgATCGGCTAATTGTTGGTTAAGTACGTGTTTAGTCCAGAAAATCAATTGTGCAGTTAACtgattgtatattttataatgtCAGAAGATGTTCATCATTCAACAGGTTAATAAAGAGCAATAACCTCAGTAA

Function

symbol description
leo1 Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Acts upstream of or within several processes, including animal organ development; melanocyte differentiation; and xanthophore differentiation. Located in nucleus. Part of Cdc73/Paf1 complex. Is expressed in brain; eye; immature eye; pharyngeal arch; and somite. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component).

GO:

id name namespace
GO:0021782 glial cell development biological_process
GO:0021529 spinal cord oligodendrocyte cell differentiation biological_process
GO:0007507 heart development biological_process
GO:0006368 transcription elongation from RNA polymerase II promoter biological_process
GO:0050936 xanthophore differentiation biological_process
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter biological_process
GO:0016570 histone modification biological_process
GO:0014032 neural crest cell development biological_process
GO:0030318 melanocyte differentiation biological_process
GO:0048701 embryonic cranial skeleton morphogenesis biological_process
GO:0005634 nucleus cellular_component
GO:0016593 Cdc73/Paf1 complex cellular_component
GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding molecular_function

KEGG:

id description
ko03021 Transcription machinery

ZFIN:

id description
ZDB-GENE-040426-2435 Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Acts upstream of or within several processes, including animal organ development; melanocyte differentiation; and xanthophore differentiation. Located in nucleus. Part of Cdc73/Paf1 complex. Is expressed in brain; eye; immature eye; pharyngeal arch; and somite. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component).

Ensembl:

ensembl_id ENSDARG00000055357

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00026692 True 2284 mRNA 0.51 11 39292911 39321484

Neighbor

gene id symbol gene type direction distance location
XLOC_013560 mapk6 coding downstream 4017 39170127 ~ 39288894 (-)
XLOC_013559 NA coding downstream 422324 38869403 ~ 38870587 (-)
XLOC_013558 BX936456.1 coding downstream 427741 38859119 ~ 38865170 (-)
XLOC_013557 NA coding downstream 524413 38759334 ~ 38768498 (-)
XLOC_013556 NA coding downstream 914706 38376678 ~ 38378205 (-)
XLOC_013562 NA coding upstream 61242 39382726 ~ 39389542 (-)
XLOC_013563 scg3 coding upstream 113105 39434589 ~ 39473055 (-)
XLOC_013564 tnfaip8l3 coding upstream 200984 39522468 ~ 39583601 (-)
XLOC_013565 BX908722.2 coding upstream 265062 39586546 ~ 39586665 (-)
XLOC_013566 BX908722.1 coding upstream 294291 39615775 ~ 39615905 (-)
XLOC_013384 BX323829.1 misc downstream 19750680 19542102 ~ 19542231 (-)
XLOC_013555 NA non-coding downstream 994956 38290081 ~ 38297955 (-)
XLOC_013569 NA non-coding upstream 470231 39791715 ~ 39796835 (-)
XLOC_013570 NA non-coding upstream 533003 39854487 ~ 39859108 (-)

Expression


Co-expression Network