XLOC_014059 (rit1)


Basic Information

Item Value
gene id XLOC_014059
gene name rit1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 24039830 ~ 24065522 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00028039
GTGAGAATTGTATGGCAGGAATTTTCTAACATCAAatatttaaacatcatttgcatcGATACAAAAGTCCCAATGGAGACAGGGATCCTGTGACACAGgTGTGTGTTACAGTAGTTTGGATGGAGTCCTCGCGGAGCACAGTGGGTCACTCCCGCGAGTACAAACTGGTGATGTTAGGAGAGGGAGGTGTGGGAAAAAGTGCCATCATCATGCAGTTTATAAGTCACAGGTTTCCAGAGGACCATGACCCTACCATTGAGGATGCCTATAAAACACAGATCCGCATTGACGATGAGCCAGCAAACCTGGACATCTTGGACACAGCGGGACAGGCGGAGTTTACAGCAATGCGTGACCAGTATATGCGAGCAGGTGAAGGTTTCATCATCTCATACTCCATCACTGACCGCCGCAGTTTCCAGGAGGCTCGTCACTTTAAGCAGCTGATTTACCGTGTACGACGCACCGTGGACACACCTGTCGTGTTGGTGGGCAACAAGTCTGACCTGGTACATCTCAGACAGGTTTCCGTAGAAGAAGGCAAACAGCTGGCGAGAGAGTTCCAGTGCCCGTTTTTTGAGACTTCGGCAGCGTTTCGTTATTACATCGATGAGGTTTTTGCAGCACTGGTGCGTCAGATCCGCCAACATGAGGCCGAAATGGTGCGGGACAGCGAGAGGAAAACCCGACGCAGCCATTCCTTCTGGAGTCGCCTTAAAGCCCCCTTCCATAGGAAACAGCAGTCCGAGCACTGACAGAGCCACAGAGGAGGGCATTCTGGGATACTGATGATTCTCTCGCCTGCAGCTGTATAACAGGTGGTTTGAGGACTGTATTTTATAGATTATTGTTGATTGTTTGCAATGACGCACTCCCAATCATTTCAGTTTCACTGTGCAGGACACACTCACTGTCATCATATGGGACGTGGGCTGATTTACTGATGTTAGAGACTAAGACTGAAGTATTAAACTTGacagcagttattatttttcatGTTCGGACAGCATTATACCTTGTGAAGGTCAAATGACAAGGGGAATGTACCTCGTATTTTAATTGATAAGAATGTCAGAAACAGCACATGGATGGATTTATAACAGGTGTTTTTGAAAAGAGGTAAGGTCATGTCAGGAGAAAGATGAAGGTCAGATGAGTTTATGAGAGGAGAGAGCATGTTTTAATGGGTAGAAAAAAAGAGATGAGCGTG
>TCONS_00028040
GAATTTTCTAACATCAAatatttaaacatcatttgcatcGATACAAAAGTCCCAATGGAGACAGGGATCCTGTGACACAGgTGTGTGTTACAGTAGTTTGGATGGAGTCCTCGCGGAGCACAGTGGGTCACTCCCGCGAGTACAAACTGGTGATGTTAGGAGAGGGAGGTGTGGGAAAAAGTGCCATCATCATGCAGTTTATAAGTCACAGGTTTCCAGAGGACCATGACCCTACCATTGGTAAGAAAGacctgatatgtttttttttttttattatttgcaatcaATTTTTCCAATCAATTCCTGTGGCTACACATCTCAGgattaagggcgtactcacactatgtacagttgccttaaaccggGCCGAAGCCTGCTTgttccccctcccgtctcccccgacggcccgcactcacattacattcgggcctgggcacgcttaaaTCATCGATAATGCACTTATTAGTAAGTGCTCAGCACAggggagatttctttagttatattgttttagccGTTTGGGATGCGGTAACACaaagtcaaatatttttaatatattttaacagatcagccacttttgacgcgcATAAAGTCCTCGTGTTGCAGGAATTAGTTCAGTTTGCAGTTTGCTAGAATcagtttgctgaaggtgca

Function

symbol description
rit1 Predicted to enable GTPase activity; calmodulin binding activity; and guanyl ribonucleotide binding activity. Acts upstream of or within embryonic viscerocranium morphogenesis and heart development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 8. Orthologous to several human genes including RIT1 (Ras like without CAAX 1).

GO:

id name namespace
GO:0007507 heart development biological_process
GO:0007265 Ras protein signal transduction biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0007165 signal transduction biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005516 calmodulin binding molecular_function
GO:0005525 GTP binding molecular_function
GO:0019003 GDP binding molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG:

id description
ko03016 Transfer RNA biogenesis
ko04031 GTP-binding proteins

ZFIN:

id description
ZDB-GENE-070912-329 Predicted to enable GTPase activity; calmodulin binding activity; and guanyl ribonucleotide binding activity. Acts upstream of or within embryonic viscerocranium morphogenesis and heart development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 8. Orthologous to several human genes including RIT1 (Ras like without CAAX 1).

Ensembl:

ensembl_id ENSDARG00000069150

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00028039 False 1210 mRNA 0.47 6 24039830 24065522
TCONS_00028040 True 651 lncRNA 0.43 3 24039848 24047266

Neighbor

gene id symbol gene type direction distance location
XLOC_014058 syt11a coding upstream 5120 23982466 ~ 24034710 (+)
XLOC_014057 si:dkey-222b8.1 coding upstream 69144 23932259 ~ 23970686 (+)
XLOC_014056 snapin coding upstream 117335 23919096 ~ 23922495 (+)
XLOC_014054 NA coding upstream 122735 23912228 ~ 23917095 (+)
XLOC_014055 CR677591.1 coding upstream 126530 23913182 ~ 23913300 (+)
XLOC_014060 pex11b coding downstream 2701 24068223 ~ 24075097 (+)
XLOC_014061 BX548249.1 coding downstream 12413 24077935 ~ 24223669 (+)
XLOC_014062 sema4ab coding downstream 259445 24324967 ~ 24392370 (+)
XLOC_014063 NA coding downstream 278483 24344005 ~ 24344658 (+)
XLOC_014064 si:dkey-81h8.1 coding downstream 329038 24394560 ~ 24399838 (+)
XLOC_014053 BX927234.1 non-coding upstream 385116 23652399 ~ 23654714 (+)
XLOC_014052 BX927216.1 non-coding upstream 398499 23637789 ~ 23641331 (+)
XLOC_014049 BX571825.5 non-coding upstream 915239 23121009 ~ 23124591 (+)
XLOC_014065 NA non-coding downstream 382499 24448021 ~ 24449198 (+)
XLOC_014067 BX530091.1 non-coding downstream 503843 24569365 ~ 24573197 (+)
XLOC_014070 NA non-coding downstream 534506 24600028 ~ 24604330 (+)

Expression


Co-expression Network