XLOC_014089 (npr1a)


Basic Information

Item Value
gene id XLOC_014089
gene name npr1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 26423590 ~ 26629117 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00028075
GATGGTTTGAGCTGTGAACTCGACGCGGAAACAAGAGTTTTGCCTCAGCAATCACGAAACACGAATCAACTGATAAGAGACAACGGCGCGGATTTACAGAGGAATTATGACACCTTTCGACGGCCTAAACTGGGATTCGTAGTCCTTTCTATCCACTTTGAAAATGGAATTGTTTCAGATGGGGCCGCTGAGGCTCACTCTTCTCGTTCTTCTGAGTGGCGTGTCATTTGGAGTAGTTGAACTGGAGCCTGTGCCTGAAAACCAGCCTCAGTCTCCCAGTGCCCATGCATCTCAAAAGAACATCACCCTGGCAGTTATCCTGCCTCTCCACAACACGGAGTACCCTTGGGCTTGGCCCCGTGTGGGCCCTGCTCTGTACTGGGCCCTGGAAAAGGTGAACTCTGATCCCAACCTGCTGGCAGGTTACCATCTACAACTGGTTTTCAATAGCAGCGAAAACAAGGAAGGACTGTGTTCGGATTCAGTGGCTCCGCTTGTGGCTGTAGACCTGAAGTTCTCATACAACCCCTGGGCATTCATCGGACCAGGTTGTGACTACTCGTCCTCACCTGTGGCACGTTTCACCACACACTGGGAGGTTCCAATGATTACCAGTGGCGCAAGAGCACTGGGTTTCAATTTATACTCTTCCATTACCAACATCGGCCCGACACACAAGAAGCTGGGCGAGTTTGTGCTCAGGATGCACCGGCATTTTGGCTGGGACAAACACGCCATGCTCATGTTTAACGATAATAAAAACGATGACCGGCCGTGTTACTTTGCCGTGGAGGGGCCGTACACACAGATGCGTGAAGACAACATCACAGCGGATGACTTGGTGTTTAATGAGGATGAAGAACCCCTACGTTATGATGAGCTTCTCCGGGATATCAGCCACAAAGCTCGTGTGGTGTATGTCTGCTGCAAGTGGGAGACGTTTCGCAAGTTGATGGTGGAGTTCTGGAGGCAGGGTTTTCCTCAGGAGGAGTACGCTTTCTTCTTCATCGACCTGTTTGGACGCAGTTTGCAGAGCCATCCTGCCAGACCATGGGCAAGAGGAGATGCTGATGACAATGCAGCCAAAGAGGCCTTTAAAAGTGTGAAGATCCTGACCTACAGAGAGCCTCAGAACCCAGAGTACAAGGACTTTGTCTCCAAGCTAAAGACAGAAGCCATGGATATGTTTAACTTCAACGTGGAAGATTCTCTGATGAATCTGATTTCTGGGTCCTTCCACGATGGAGTCATGCTTTATTCTCATGCCCTGAATGATACTATGGATCGTTCGGGTTCGAGACCTCCGGGAGACGTGGTCAACAAGAGGATGTGGAATCGCACATATCATGGTGTTACCGGACTTGTGCAACTGGATGAGAATGGTGATCGGGAGATTGACTTTGCTCTATGGGACATGACCGATACAAAGACAGGAGATTATCAGATTGTGTCTGTGTATAACGGCAGTCAGAAGCAGATGATTTTGGAGCCAGGAATGAAGGTGCACTGGCTGAAGGGAAGGCCGCCTCCAGATATTCCTGAGTGTGGCTTCAAAAATGACAACCCTGCCTGTCTGGCAAAGACAGTCACCATGCACCAGATGATCTCCATAGTGGTGTGCTTCATCTTTATCATCATCGTTACAGTCACAGTCTTCATATACAGGAAGCTGAAGTTGGAGAATGAGTTGACCGCTCAGCTGTGGCGTGTGCACTGGGAGGACATCCAGATGAGCAACACGGAGAAGGTCCTGCGCAGAGCCTGCAGCAAACTCACCATATCCCTGAGAGGCTCTAACTATGGGTCACTGCTCACTATGGATGGAAACTTCCAGATCTACGCTAAGACTGGCTACTACAAGGGAAACATAACAGCCATTAAGTATGTCAACAAGAAACGCATCGAGCTCACCAGGAAAGTGCTGTTTGAACTCAAACATATGCGTGATGTCCAGAATGAGCACCTTACCCGCTTTATCGGTGCTTGTATCGACCCACCAAACATCTGCATCCTCACTGAGTACTGCCCTCGAGGAAGCTTACAGGATCTGATGGAGAGTGAAGGAATCACGCTGGACTGGATGTTTCGCTATTCTCTCATCAATGACATTGTTAAGGGAATGGCGTTCCTCCACAACAGCGTCATCGTCTCCCATGGCAACTTGAAGTCTTCCAACTGCGTGGTGGACAGTCGCTTCGTGCTGAAGATAACCGATTATGGGCTGGAAAGTTTCCACAAGGACAGCAATTTGGATGACGTGCATGCTTTCTATGCACGTCAGCTGTGGACGGCCCCTGAGCTTCTGCGTGCTGATAATCCACCAGCGTGTGGAACACAGAAGGGTGACGTCTACAGCTTTGGCATCATCCTGCAGGAGCTGGCTCTGCTGAAGGGCGTCTTCTACCTGGAGGGCCCCTGTCTCAGCCCTAAAGAGATCATCGAACGTGTGGTGGAGGGCCGCTGGCCATACCTGCGTCCCCTACTGTGTCCTCAGAGTCACAGTGAGGAGATGGGACAGTTGATGCTGCGCTGCTGGTCAGAGGACGTCAACGAGAGGCCAGACTTCAGCCAGATTAAAGTACTGCTCCGCAAGAACAACTGTGGATACGGCTCTAATATTCTGGATAACCTCCTGTCCCGTATGGAGCAATATGCCAATAACCTGGAGGAGCTGGTGGAGGAGAGGACACAGGCGTACCATGAGGAGAAACGAAAAGCTGAAGCTCTGCTCTATCAGATTCTCCCACACTCAGTGGCCGAGCAGCTGAAGCGAGGAGAGATGGTTCAGGCTGAAGCCTTTGACTCTGTCACCATCTACTTCAGTGACATTGTGGGCTTCACAGCGTTATCCGCTGAAAGCACGCCTATGGAGGTGGTGACGCTGCTGAATGATCTCTACACTTGCTTTGATGCAATCATTGACAATTTCGACGTATACAAGGTGGAGACCATCGGCGATGCGTATATGGTGGTGTCAGGTCTGCCCGTGAGGAACGGCAAACTGCACGCCCGTGAGATCGCCCGCATGTCTCTGGCTCTGCTGGAGGCCGTACACTCATTCAGAATCCGCCACCGACCAAACCTGCAGCTCCGTCTGCGCATCGGCATCCACAGCGGTCCTGTGTGTGCAGGGGTGGTGGGTTTGAAGATGCCTCGTTATTGTTTGTTTGGTGACACAGTCAATACAGCTTCACGTATGGAATCCAATGGAGAAGCTCTAAAGATCCATGTGTCAGAAGCCACACGGGCCGTCCTGCAGGAGTTCAACTGCTTCCAGCTGGAGCTCAGAGGAGATGTGGAGATGAAGGGAAAGGGCCGGATGAGGACGTATTGGCTGCTAGGAGAAATCAGCTCTAACAATGCCTAAAAACTAAATGACTGACAGAAAgagcaacaaaacaaacacatctaAACAAGTACTGGGACTGAAAGACCAGACCAGAAATTCTTCAAAAAAAACTGGGTCCTGTTCATCTGTCATCACGCAGAGCTTAACATTCTTGCTTCACAGgaatctcactttttttttttaccaagtaaACGCACGAGAAAAGAAACAGTACTTGAGCAGAATCCTTTAGACAAATGGAAGGTGGTATAACACAGTGCCAGATAAAGGTCTGATGAGTGTGTCCAGTGTTTTTACGGGTCTTGTAGGGGTTTTTGTTTCATCATTGTAGGTCTTCATCCAGATTTTCCTTCAGGAGTTGTATGGGTATGTTTATTGTTCATACAGAGACACAGATCTGTAGTTTTTTTTAGCCATGCAAAATGTTCCCGATTCTTCTTCTGGGACGCAGGTCAATTCGAAACGCCTCTCTCTGCCAAATCTGATCCAGAGGGTTTTGGGATGAAAGTTACGCACATTAGgagaaataataatacatgtcAAGTATGATTAGACGTGTGCAATGATGGATTTTGTTCTTAGAATCCCTGCAGAAATCCACACGAGTATTGATGTTGCAATAGTGTTTCAGCTGAAACCAGCACAGggttgattttgttttttgttaatagACAAATggagttgtgttttgtttttttcatccaTCATTATTAGATTACGTTAATGTTAGTGATTAATGATAAAGGATTAGTTCAAAATTCTGTCAATAATTACTCattctcatgttgttccaaaccctaAGGTATTTTGGATGAAATTTGAGAGCTCTCTTATTCTCCATATGCAGCAATGTTCCCGTCTCGTTCAAAGAACCAAATAACATCATCAAAACAGTCCATTTGTGTTGAGTGGTTCAATCAGAGTATTATGAAGCTACAAGAATACTTTCGTGCACATATAAAACAACTCTTTTTCTAGTTTTTCCGTCAGTGTCAGTAGTAAAGGGCGTCACACACCAGATGCACCACTCAGCTCcacgacacggcgcgcacatgacagttaaaagtatcgcacaccagacgcgcacattcgcatgctatttaaaatgaaattaatcagatggcgctctggagAATAATGGATCTAATGGAGAATAATGGATCTTTCgggtttcatctaaaatatccccATTTGTCTTCTGAAGACAAACAAATGTCTCTGGGGCTTGGACTTAATTAATATTTCACTCTAAAACATTTGGGGTCTGTAAGATTTTGTAAGTTGATACATTACGTCAGTAAAAGCTGAAAGTTTATATCacttttaatattacatttcaattcatgttttgttttttcttgatTTAATGGATCACAATTTCCACTAAattattaaaggtgctgtgtgtaagtttgtgactcttctgaagcataaaaatactatatgTTTGGAGATATTTAAGAACCTTGAGcaagtgaacatttttgtttatctgaagTCAGATACTttactttgaaaatgtctgttacgTTCTGGAACGCTTTCTTTGTTTCGTTTCTTTCAACCTGATTCagtatttgattcattcagtcaggaaggctcacAAAGCATGCACCCatgaccgaaatgtgacctccagTGGAAAGTTGCTGACTCTGAAataagacgcagattcagagttccacgtgaggttataaattagcaaataatataaatattatgaacacaaacattaggtgagcaggttacattgttacCCTGTGCCCTTACCACACGATACACAACAATATTTGCAGTGATTAGCAAtttagctgtttgcacc
>TCONS_00028076
ATGGAATTGTTTCAGATGGGGCCGCTGAGGCTCACTCTTCTCGTTCTTCTGAGTGGCGTGTCATTTGGAGTAGTTGAACTGGAGCCTGTGCCTGAAAACCAGCCTCAGTCTCCCAGTGCCCATGCATCTCAAAAGAACATCACCCTGGCAGTTATCCTGCCTCTCCACAACACGGAGTACCCTTGGGCTTGGCCCCGTGTGGGCCCTGCTCTGTACTGGGCCCTGGAAAAGGTGAACTCTGATCCCAACCTGCTGGCAGGTTACCATCTACAACTGGTTTTCAATAGCAGCGAAAACAAGGAAGGACTGTGTTCGGATTCAGTGGCTCCGCTTGTGGCTGTAGACCTGAAGTTCTCATACAACCCCTGGGCATTCATCGGACCAGGTTGTGACTACTCGTCCTCACCTGTGGCACGTTTCACCACACACTGGGAGGTTCCAATGATTACCAGTGGCGCAAGAGCACTGGGTTTCAATTTATACTCTTCCATTACCAACATCGGCCCGACACACAAGAAGCTGGGCGAGTTTGTGCTCAGGATGCACCGGCATTTTGGCTGGGACAAACACGCCATGCTCATGTTTAACGATAATAAAAACGATGACCGGCCGTGTTACTTTGCCGTGGAGGGGCCGTACACACAGATGCGTGAAGACAACATCACAGCGGATGACTTGGTGTTTAATGAGGATGAAGAACCCCTACGTTATGATGAGCTTCTCCGGGATATCAGCCACAAAGCTCGTGTGGTGTATGTCTGCTGCAAGTGGGAGACGTTTCGCAAGTTGATGGTGGAGTTCTGGAGGCAGGGTTTTCCTCAGGAGGAGTACGCTTTCTTCTTCATCGACCTGTTTGGACGCAGTTTGCAGAGCCATCCTGCCAGACCATGGGCAAGAGGAGATGCTGATGACAATGCAGCCAAAGAGGCCTTTAAAAGTGTGAAGATCCTGACCTACAGAGAGCCTCAGAACCCAGAGTACAAGGACTTTGTCTCCAAGCTAAAGACAGAAGCCATGGATATGTTTAACTTCAACGTGGAAGATTCTCTGATGAATCTGATTTCTGGGTCCTTCCACGATGGAGTCATGCTTTATTCTCATGCCCTGAATGATACTATGGATCGTTCGGGTTCGAGACCTCCGGGAGACGTGGTCAACAAGAGGATGTGGAATCGCACATATCATGGTGTTACCGGACTTGTGCAACTGGATGAGAATGGTGATCGGGAGATTGACTTTGCTCTATGGGACATGACCGATACAAAGACAGGAGATTATCAGATTGTGTCTGTGTATAACGGCAGTCAGAAGCAGATGATTTTGGAGCCAGGAATGAAGGTGCACTGGCTGAAGGGAAGGCCGCCTCCAGATATTCCTGAGTGTGGCTTCAAAAATGACAACCCTGCCTGTCTGGCAAAGACAGTCACCATGCACCAGATGATCTCCATAGTGGTGTGCTTCATCTTTATCATCATCGTTACAGTCACAGTCTTCATATACAGGAAGCTGAAGTTGGAGAATGAGTTGACCGCTCAGCTGTGGCGTGTGCACTGGGAGGACATCCAGATGAGCAACACGGAGAAGGTCCTGCGCAGAGCCTGCAGCAAACTCACCATATCCCTGAGAGGCTCTAACTATGGGTCACTGCTCACTATGGATGGAAACTTCCAGATCTACGCTAAGACTGGCTACTACAAGGGAAACATAACAGCCATTAAGTATGTCAACAAGAAACGCATCGAGCTCACCAGGAAAGTGCTGTTTGAACTCAAACATATGCGTGATGTCCAGAATGAGCACCTTACCCGCTTTATCGGTGCTTGTATCGACCCACCAAACATCTGCATCCTCACTGAGTACTGCCCTCGAGGAAGCTTACAGGATCTGATGGAGAGTGAAGGAATCACGCTGGACTGGATGTTTCGCTATTCTCTCATCAATGACATTGTTAAGGGAATGGCGTTCCTCCACAACAGCGTCATCGTCTCCCATGGCAACTTGAAGTCTTCCAACTGCGTGGTGGACAGTCGCTTCGTGCTGAAGATAACCGATTATGGGCTGGAAAGTTTCCACAAGGACAGCAATTTGGATGACGTGCATGCTTTCTATGCACGTCAGCTGTGGACGGCCCCTGAGCTTCTGCGTGCTGATAATCCACCAGCGTGTGGAACACAGAAGGGTGACGTCTACAGCTTTGGCATCATCCTGCAGGAGCTGGCTCTGCTGAAGGGCGTCTTCTACCTGGAGGGCCCCTGTCTCAGCCCTAAAGAGATCATCGAACGTGTGGTGGAGGGCCGCTGGCCATACCTGCGTCCCCTACTGTGTCCTCAGAGTCACAGTGAGGAGATGGGACAGTTGATGCTGCGCTGCTGGTCAGAGGACGTCAACGAGAGGCCAGACTTCAGCCAGATTAAAGTACTGCTCCGCAAGAACAACTGTGGATACGGCTCTAATATTCTGGATAACCTCCTGTCCCGTATGGAGCAATATGCCAATAACCTGGAGGAGCTGGTGGAGGAGAGGACACAGGCGTACCATGAGGAGAAACGAAAAGCTGAAGCTCTGCTCTATCAGATTCTCCCACACTCAGTGGCCGAGCAGCTGAAGCGAGGAGAGATGGTTCAGGCTGAAGCCTTTGACTCTGTCACCATCTACTTCAGTGACATTGTGGGCTTCACAGCGTTATCCGCTGAAAGCACGCCTATGGAGGTGGTGACGCTGCTGAATGATCTCTACACTTGCTTTGATGCAATCATTGACAATTTCGACGTATACAAGGTGGAGACCATCGGCGATGCGTATATGGTGGTGTCAGGTCTGCCCGTGAGGAACGGCAAACTGCACGCCCGTGAGATCGCCCGCATGTCTCTGGCTCTGCTGGAGGCCGTACACTCATTCAGAATCCGCCACCGACCAAACCTGCAGCTCCGTCTGCGCATCGGCATCCACAGCGGTCCTGTGTGTGCAGGGGTGGTGGGTTTGAAGATGCCTCGTTATTGTTTGTTTGGTGACACAGTCAATACAGCTTCACGTATGGAATCCAATGGAGAAGCTCTAAAGATCCATGTGTCAGAAGCCACACGGGCCGTCCTGCAGGAGTTCAACTGCTTCCAGCTGGAGCTCAGAGGAGATGTGGAGATGAAGGGAAAGGGCCGGATGAGGACGTATTGGCTGCTAGGAGAAATCAGCTCTAACAATGCCTAA

Function

symbol description
npr1a Predicted to enable guanylate cyclase activity; natriuretic peptide receptor activity; and peptide hormone binding activity. Acts upstream of or within axon guidance and cardiac muscle cell proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; eye; heart; integument; and kidney. Human ortholog(s) of this gene implicated in Miura type epiphyseal chondrodysplasia; acromesomelic dysplasia, Maroteaux type; essential hypertension; and myocardial infarction. Orthologous to several human genes including NPR1 (natriuretic peptide receptor 1).

GO:

id name namespace
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0006182 cGMP biosynthetic process biological_process
GO:0009190 cyclic nucleotide biosynthetic process biological_process
GO:0060038 cardiac muscle cell proliferation biological_process
GO:0007165 signal transduction biological_process
GO:0007168 receptor guanylyl cyclase signaling pathway biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0017046 peptide hormone binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0016829 lyase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016849 phosphorus-oxygen lyase activity molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004383 guanylate cyclase activity molecular_function
GO:0001653 peptide receptor activity molecular_function
GO:0016941 natriuretic peptide receptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060503-539 Predicted to enable guanylate cyclase activity; natriuretic peptide receptor activity; and peptide hormone binding activity. Acts upstream of or within axon guidance and cardiac muscle cell proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; eye; heart; integument; and kidney. Human ortholog(s) of this gene implicated in Miura type epiphyseal chondrodysplasia; acromesomelic dysplasia, Maroteaux type; essential hypertension; and myocardial infarction. Orthologous to several human genes including NPR1 (natriuretic peptide receptor 1).

Ensembl:

ensembl_id ENSDARG00000031751

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00028075 False 5171 mRNA 0.46 22 26423590 26629117
TCONS_00028076 True 3204 mRNA 0.51 21 26424734 26627313

Neighbor

gene id symbol gene type direction distance location
XLOC_014088 mylipa coding upstream 44935 26340736 ~ 26378655 (+)
XLOC_014087 BX842609.1 coding upstream 230654 26192822 ~ 26192936 (+)
XLOC_014086 jarid2b coding upstream 267059 25971000 ~ 26156531 (+)
XLOC_014085 tac1 coding upstream 770405 25649626 ~ 25653185 (+)
XLOC_014084 sdhaf3 coding upstream 874960 25526354 ~ 25548630 (+)
XLOC_014091 ints3 coding downstream 10979 26640096 ~ 26673855 (+)
XLOC_014092 si:dkey-27c15.3 coding downstream 52731 26681848 ~ 26730250 (+)
XLOC_014093 FP085398.3 coding downstream 176649 26805766 ~ 26805882 (+)
XLOC_014094 FP085398.1 coding downstream 199385 26828502 ~ 26844582 (+)
XLOC_014095 nelfe coding downstream 293663 26922780 ~ 26932829 (+)
XLOC_014081 CR855860.3 non-coding upstream 1248198 25175272 ~ 25175392 (+)
XLOC_014079 CR855860.2 non-coding upstream 1271013 25151416 ~ 25152577 (+)
XLOC_014078 NA non-coding upstream 1362623 25003517 ~ 25060967 (+)
XLOC_014077 NA non-coding upstream 1440082 24959229 ~ 24983508 (+)
XLOC_014097 NA non-coding downstream 404756 27033873 ~ 27041528 (+)
XLOC_014104 NA non-coding downstream 1345548 27974665 ~ 27976483 (+)
XLOC_014106 BX511306.1 non-coding downstream 1514018 28143135 ~ 28143254 (+)
XLOC_014109 NA non-coding downstream 2159851 28788968 ~ 28824390 (+)

Expression


Co-expression Network