XLOC_014131 (mfsd2ab)


Basic Information

Item Value
gene id XLOC_014131
gene name mfsd2ab
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 30867845 ~ 30884054 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00028148
CACGGGTTGATTCCAAAAGGAACGGTGTATACGAACAGGATCAGTTTATGTTTTAGTCGAGTCGATTTATTTTTCAAACTTTTGAGATAGCACTTAATAACTGGCTTCACAGGAAAGGTGTAAACGATTTTCAAATTTTAAAGCGAGATGGCAAAAGGAGAGGGAGCAGAGCAGTACACCAATACCAGCCTCTTACAAAAACCCAGCCCAGACGAAGTCAAATTGGCGAAGCATGAAACAAAGAGCCGGTTGTCGGTGTGCAGCAAGTTGTGTTATGCCATTGGAGGAGCACCATATCAGATAACAGGATGTGCAATTGGCTTCTTCCTTCAGATCTACTTGCTGGACGTTGCTTTGTTGGACCCATTCTATGCCTCCATCATCTTGTTTGTGGGTCGAGCATGGGATGCCGTCACAGACCCTACAGTGGGATTTCTTGTCAGTCGGACTCCATGGACAAGATTTGGACGAATGATGCCTTGGATTGTTTTGTCTACTCCATTTGCTGTACTTTGCTATTTCCTCATCTGGTACGTGCCCTCTGTTGACCAAGGGAAAGTTGTCTGGTATCTAATCTTCTACTGCTGCTTCCAAACATTACAGACATGCTTCCACGTGCCCTACTCTGCTCTCACCATGTTCATCAGCACTGAACAGAAAGAGAGGGATTCGGCTACAGCTTACCGAATGACTGTTGAGGTTTTGGGCACACTCATAGGCACTGCTATTCAGGGTCAGATTGTGGGAATGGCCAATGCTCCCTGTATCAGCACTGAGATTGACCTGAACTCCACGGGTTTGGAGGTGGCTCCTGACGTCAACATCACTGACCCTCATGTTTCACTGCAGGACCTGAGAAATGCTTACATGATTGCATCTGGTGTCATCTGCGCGATCTATGTTGTCTGTGCTGTGGTCCTGTTCCTTGGTGTGAAAGAACAAAAGGACACATGCAGGGTGAGGACTGAGCCCATGTCATTTTTCCAGGGTATTTGCATGGTAATGGGTCACGGTCCTTATGCCAAGCTGGTCATGGGCTTCCTCTTCACCTCTCTGGCCTTTATGCTTCTGGAAGGAAACTTTGCTTTGTTCTGCATCTACAACCTGGGCTTCAGAAATGACTTCCAAAATGTCTTGCTCGTCATTATGCTCTCCGCCACACTTGCTATCCCATTTTGGCAATGGTTCCTCACGAAATTTGGCAAGAAAACCGCAGTGTATATTGGGACTACATCTGTGGTGCCTTTCCTGATCTCCGTAGTCTTGGTGCCAAGCAGTCTTGCTGTGACTTACATTGCGTCGTTTGCTGCTGGAGTCAGTGTAGCAGCAGCTTTCCTCTTGCCATGGTCCATGCTTCCCGACGTTGTAGATGATTTTAAAGTCCAAAATCCTGAATCTCAAGGCCATGAAGCCATCTTCTACTCCTTCTATGTGTTCTTCACCAAGTTTGCATCTGGAGTTTCTTTGGGGGTCTCGACTCTTAGTCTTGATTTCGCTGGCTATGTGACGAGAGGTTGCACGCAACCCGGTGAAGTCAAGTTAACCTTGAAAATCCTGGTGTCTGCTGCTCCCATAGTCTTGATCATTATCGGACTGCTAATATTCATCTCTTATCCCATCAATGAGGAAAAGCGACAAGGCAACCGCAAACTGCTTAATGAACAAAGAGAAAACGAGATGGATTCAGAAACGGACTCCACTGAGCTCAATGTGGTTTAATACCACCAAAAACCCTGGACGGGACATTGTGCCATTTGAGTTGGACCAACAGAGCTGGAACAAACCAGAGCGAATACTCTGAACCAACCATGCCTTGTGGCTGAAAGCTTCCAGCATCATCACAAATATGGATCAACTGGAAACGTAGCCTGTGCCAGCTCAAGCTCAATGTGCCTTGCCATTTTCAGTTGCAAGAACTATTATGGAGTCGGCTTGTATGTGTTGCCAGGATTTGTCCTGCTtactggttaaaaacaaaaaaagccagcTTTTGAAAAGCACACATCTATATACTGCACTAAGAAAATGACGAGGTGGGACATATCTACCTTTTAGATGAGACTTGAAACATTTACAAAGGTTTTTAGGTGCTAAAACCAAAAATGCTTTTCAATCTGATTTGAAAAGTGCATTTTGGAAGGAATATCTGTGAACTGTACACTACAATGTttgtatgtaatttaatatttataaatgcttTTGTGCTTCTAACTAAATGAGCAAACTTGAAACCATGACACCAAGTGGGGTTTGATTACATCAAACTGTAGTATTGCACACAAAGTTACCACCTTTTTCTTCTTGTATTACTTTCCTTTTCATCTTCGTGGGGCGTACAGAGGGATGTGCTGAGGGAAAAGTGTACAAATTTGATCCCTCAACACCTTCGAATTAGATCGATCAATATCCACTAAAGTACTGCTGAGGCTTTAAATTAGATGAACGCCATCAGAATGTGTGGGCTAGAAATGTACGATTATTCCTTCTGGTGAGAGGTGAagattatttaagtatttattactTTTCTTTTAAATCATATGTTGATTTGATTGTCTTTTTCTCTCATCTTCCTTAATTTATCTTGTTTAAGGGCCTGTCACATAAAATAAGGGCAATTAGGGTAGAGCTGTCACTGCTGAATTATATCTATTATGCCATTAATTCCTATGGAACAGCCAACCAGTGTGTTTACAGGTGACACTACTGTTTGTTTAggtgttaaatgaatttgatttcTGGTCTGATCGTTTTGATTCACCGTCTAGTCTAGTGCTTTTATTATTGTATAGTATTAATGTTGGTTCTCAGCCTGTAACTAAGTGTCAAAGATCTGAATGCCAAGTGTTCCCTACAAATGTGTACGTGCTGTGAAATATGTACATAAACCTGTTTTCATTTTCTATCTTTTGGGGGAAAATGGAATTATTTGTAAATAACATTTGTGTATATACGAGTGTTGTATGTTATACATATGTACATTTGATGCACATTGAACTCGCATCGGTGCAGTTTTTTTGCATGTTTCTGATTAATACTGTTTTCTAACATGTCAGTTTTGTATTGATGCAGCATCTGTGACATTTCGATTGCTCTCATTAACCCCAGTTTGTGGTTCTCTGTCAAGATTTCCGCATTCTGATATCAAAAATacagttaatgtaaataataaatgtgcTGATGTTTGTacaaagattttatatatatattttggatggaatcctaaatgtgtgtgtgcgtgtgtgtgtgtagttatttaaaagaaacaatggaaataGTCGTTAATAAATGGTAATTGATATTAAAA
>TCONS_00028149
TTTCCTCTATTTTAGCTCTCCGCCACACTTGCTATCCCATTTTGGCAATGGTTCCTCACGAAATTTGGCAAGAAAACCGCAGTGTATATTGGGACTACATCTGTGGTGCCTTTCCTGATCTCCGTAGTCTTGGTGCCAAGCAGTCTTGCTGTGACTTACATTGCGTCGTTTGCTGCTGGAGTCAGTGTAGCAGCAGCTTTCCTCTTGCCATGGTCCATGCTTCCCGACGTTGTAGATGATTTTAAAGTCCAAAATCCTGAATCTCAAGGCCATGAAGCCATCTTCTACTCCTTCTATGTGTTCTTCACCAAGTTTGCATCTGGAGTTTCTTTGGGGGTCTCGACTCTTAGTCTTGATTTCGCTGGCTATGTGACGAGAGGTTGCACGCAACCCGGTGAAGTCAAGTTAACCTTGAAAATCCTGGTGTCTGCTGCTCCCATAGTCTTGATCATTATCGGACTGCTAATATTCATCTCTTATCCCATCAATGAGGAAAAGCGACAAGGCAACCGCAAACTGCTTAATGAACAAAGAGAAAACGAGATGGATTCAGAAACGGACTCCACTGAGCT

Function

symbol description
mfsd2ab Predicted to enable lysophospholipid:sodium symporter activity. Acts upstream of or within lysophospholipid transport. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in central nervous system. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 15. Orthologous to human MFSD2A (major facilitator superfamily domain containing 2A).

GO:

id name namespace
GO:0060856 establishment of blood-brain barrier biological_process
GO:0051977 lysophospholipid transport biological_process
GO:1990379 lipid transport across blood-brain barrier biological_process
GO:0015908 fatty acid transport biological_process
GO:0071702 organic substance transport biological_process
GO:0008643 carbohydrate transport biological_process
GO:0006869 lipid transport biological_process
GO:0045056 transcytosis biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0051978 lysophospholipid molecular_function
GO:0015293 symporter activity molecular_function
GO:0005215 transporter activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040801-89 Predicted to enable lysophospholipid:sodium symporter activity. Acts upstream of or within lysophospholipid transport. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in central nervous system. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 15. Orthologous to human MFSD2A (major facilitator superfamily domain containing 2A).

Ensembl:

ensembl_id ENSDARG00000035909

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00028148 False 3304 mRNA 0.41 14 30867845 30884054
TCONS_00028149 True 572 processed_transcript 0.46 5 30879788 30882456

Neighbor

gene id symbol gene type direction distance location
XLOC_014130 NA coding upstream 24612 30841639 ~ 30843233 (+)
XLOC_014129 NA coding upstream 31640 30832290 ~ 30836205 (+)
XLOC_014128 NA coding upstream 65857 30800052 ~ 30801988 (+)
XLOC_014127 NA coding upstream 142142 30724996 ~ 30725703 (+)
XLOC_014126 fam49al coding upstream 182971 30633453 ~ 30684874 (+)
XLOC_014132 yars1 coding downstream 652 30884706 ~ 30895273 (+)
XLOC_014133 NA coding downstream 84958 30969012 ~ 30970025 (+)
XLOC_014134 sync coding downstream 106075 30990129 ~ 30997794 (+)
XLOC_014135 ankmy2b coding downstream 158948 31043002 ~ 31054326 (+)
XLOC_014136 sostdc1b coding downstream 177664 31061718 ~ 31063020 (+)
XLOC_014125 CU463182.1 non-coding upstream 236785 30630943 ~ 30631060 (+)
XLOC_014137 NA non-coding downstream 254773 31138827 ~ 31153090 (+)
XLOC_014138 NA non-coding downstream 273593 31157647 ~ 31218099 (+)
XLOC_014139 NA non-coding downstream 366866 31250920 ~ 31348348 (+)
XLOC_014144 BX957279.1 non-coding downstream 707470 31591524 ~ 31591540 (+)

Expression


Co-expression Network