XLOC_014239 (col1a2)


Basic Information

Item Value
gene id XLOC_014239
gene name col1a2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 40983221 ~ 41002980 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00028304
CTGGACACGCAGTCAAGGGAACCTCCTGCCATATAAATAGGGCTGGTCGCTCTTTATTATTCTAGCATCACGGCAGCAGGTTCCTGCTAAGTTTGGAGTTTATACCACAACTGTATGCCTGCTTGAAGTAGTTAAACCAGGGCACTGCGGCACAAGGAGTCTGCATGTCGGTTTAGACATGCTCAGCTTTGTGGATACCCGGATTCTGTTGCTGCTTGCAGTGACTTCGTACCTAGCATCATGTCAATCGGGCCTCAAGGGACCAAAAGGACCCAGAGGTGAGAGGGGTCCTAAGGGACCTGATGGAAAACCCGGCCGACCTGGACTTCCTGGCCCTGCTGGCCCTCCTGGCCCCCCTGGTCTTGGTGGAAACTTCGCTGCTCAGTATGATGGCGCTAAAGGACCTGACCCCGGCCCTGGACCTATGGGTTTGATGGGACCCAGAGGACCTTCTGGATCTCCTGGTGCTCCTGGAGCTCAAGGACTGCAAGGACATGCTGGTGAGCCTGGAGAGCCCGGACAGGCTGGAGCTATTGGTGCTCGTGGCCCTCCTGGACCCCCTGGCAAAAATGGTGAAGATGGCAACAATGGCAGACCTGGAAAGCCTGGAGACAGAGGAGTCCTTGGAGCTCAGGGTGCCCGTGGTTTCCCAGGAACTCCTGGACTTCCTGGCATGAAGGGACACAGAGGTTACAATGGTATTGATGGACGCAAAGGAGAGCCTGGCGCAGCTGGTGCCAAGGGTGAAAATGGTGCCGCTGGATCAAATGGAACCCCCGGACAGAGAGGTGGTCGTGGTCTTCCTGGTGAGAGAGGTCGTGTTGGCCCTGCTGGCCCAGCTGGTGCTCGCGGTGCTGATGGTAACACTGGTCCTGCTGGCCCTGCTGGACCTTTGGGCTCAGCTGGTCCTCCTGGTTTCCCTGGTGCACCTGGACCCAAGGGAGAACTTGGACCCGCTGGTCCCACTGGACCATCTGGAGCTCAGGGACAAAGAGGAGAGCCAGGCCCGAACGGTGCCGTTGGCCCCGTTGGACCCCCTGGTAACCCTGGTGCTAATGGTATCAATGGTGCTAAAGGAGCAGCTGGTCTTCCTGGAATTGCTGGTGCCCCTGGTTTCCCTGGCCCTAGAGGAGGCCCTGGCCCACAGGGACCTAGTGGAGCTTCTGGTCCAAGAGGTCTTGGTGGTGACCCCGGACCTGTTGGAGTGAAGGGAGATTCTGGTGTGAAGGGAGAGCCTGGTAGTGCTGGTCCTCAGGGGCCTCCTGGTCCTTCTGGTGAGGAGGGCAAGAGAGGGTCAACTGGAGAGCAGGGACCTACTGGACCTTTGGGACTGCGTGGACCTAGAGGAGCCGCTGGTACTCGTGGTCTGCCTGGTCTGGCTGGCAGGTCAGGCCCAATGGGCATGCCTGGTCCTCGTGGTGGTGTTGGTGCACCTGGAGCCCGTGGACCTCCTGGAGATGCTGGTCGTGCTGGTGAGGCTGGTCTTGTTGGAGCCAGAGGTCTCCCTGGTAGCCCTGGCAGTTCTGGACCCCCTGGAAAGGAAGGACCTTCTGGTGCCGCTGGTCAAGATGGTCGCACCGGACCCCCTGGCCCAACTGGACCCAGAGGCCAGCCTGGTAACATTGGATTCCCTGGTCCCAAAGGACCTTCTGGCGAGGCTGGCAAGCCTGGTGAGAAGGGACCTGTTGGCCCTACTGGACTGAGAGGCAGCCCTGGTCCTGATGGTAACAATGGTCCTGCTGGTCCTGTTGGACTTGCTGGTGCCCCTGGTGAGAAAGGAGAGCAGGGACCCTCTGGTGCTCCTGGTTTCCAGGGTCTTCCTGGCCCCGCTGGACCTGTTGGTGAGGCTGGCAAGCCTGGTGATAGAGGTATCCCTGGAGATCAAGGTGTATCAGGACCTGCTGGTGTGAAGGGAGAGCGTGGTAACCCTGGACCTGCTGGTGCTGCTGGCGCTCAGGGACCCATTGGTGCTCGTGGACCTTCTGGTACTCCTGGCCCTGATGGAAACAAGGGAGAGCCTGGTGCAGTTGGACCTGCTGGTGCCCCTGGACCACAGGGAGCTGCTGGTATGCCTGGTGAGCGTGGTGCTGCTGGCACCCCTGGAGCTAAGGGAGAGAAGGGTGAGGCTGGATACAGAGGACTGGAGGGCAATGCTGGAAAAGATGGTGCCCGTGGTGCTCCTGGACCCAGTGGACCCCCTGGACCTGCTGGTGCTAATGGTGACAAGGGTGAGACTGGCTCCTTTGGTCCTCCTGGACCTGCTGGTCCTCGTGGTGCCCCTGGTGAGCGTGGTGAGTCTGGCCCTGCTGGACCTTCCGGTTTTGCTGGACCCCCTGGTGCTGATGGCCAGACTGGACCAAGAGGTGAGAAAGGACCTGCTGGTGGAAAGGGTGACGCTGGACCCGCTGGCCCTGCCGGTCCCGCTGGAAATACTGGACCCCTTGGTCCTTCTGGTCCTGTTGGCCCACCTGGTGCCCGTGGTGACAGTGGTCCCACTGGTCTGACTGGCTTCCCTGGTGCTCCTGGTAGAGTTGGACCTCCTGGTCCTGCTGGTATTGTTGGACCTGCTGGTCTCACTGGTCCCGCTGGAAAGGATGGCCCACGTGGTCCTCGTGGTGATGTTGGCCCTGCTGGTCCCCCAGGAGAGAATGGAATGATTGGACCTCTTGGTCTGGCTGGTGAGAAGGGACCCCCTGGAGAGGCTGGTGCACCTgGAGCACCTGGACCTGCTGGGCCTCAGGGTCAGCTGGGATCACAGGGATTCAATGGTCTTCCTGGCTCCAGAGGTGACCGTGGTCTTCCTGGTATCCCCGGATCAGTTGGTGAACCTGGAAGAGTTGGCCCTGCTGGTGCCCCTGGTGCCCGTGGACCCGGTGGCAACATTGGCATGCCTGGTATGACTGGTCCTCAGGGTGAGGCTGGACGTGAGGGAAGCCCTGGCAATGATGGACCTCCTGGCCGTCCTGGTGCTGCTGGAATTAAGGGTGACCGTGGTGAGCCTGGTTCCCCTGGAACTGCTGGACCTGTTGGTGCTCCTGGACCCAATGGACCATCAGGCGCTGTTGGCAGACCTGGAAACCGTGGTGAATCTGGTCCTTCTGGTCCTACTGGCGCTGTTGGACCTGCTGGAGCAAGAGGTGCACCTGGCCCTGCTGGACCTCGTGGTGAGAAGGGTGTTGCTGGAGAAAAAGGAGACAGGGGTATGAAGGGACTTCGTGGACATCCTGGTCTGCAGGGAATGCCCGGACCTAACGGTCCTTCTGGTGACAGTGGGCCTGCTGGCATTGCTGGACCTTCCGGTCCAAGAGGCCCAGCTGGTCCCAATGGCCCCGCTGGTAAAGATGGTTCAAATGGCATGCCTGGTGCAATTGGACCCCCAGGACACCGTGGTCCCGCTGGACATGTTGGACCTGCTGGTCCTCCTGGATCTCCTGGTCTTCCCGGACCCCCTGGCCCATCTGGAGGTGGATATGACACATCTGGAGGCTATGATGAGTACAGAGCTGACCAGGCCTCTCTTAGAGCCAAGGATTACGAGGTGGATGCCACCATCAAGTCCTTGAACACTCAGATTGAGAATCTGCTTTCCCCTGAGGGCTCAAAGAAGAACCCCGCTCGTACTTGCCGTGACATCAGGCTCAGCCACCCAGAATGGAGCAGCGGTTTCTACTGGATCGACCCCAACCAGGGCTGCACAATGGATGCCATCAAGGCCTTCTGCGACTTCTCTACTGGCCAGACCTGCATCCACCCCCACCCAGAGAGCATCCCACGCAAGAACTGGTACAGAAGCTCCCAGGAGAAGAAACACACCTGGTTTGGCGAGACTATCAACAGTGGTACTGAGTTTGCTTACAATGACGAGACCCTGAGCCCACAATCCATGGCTACTCAGCTGGCCTTCATGCGTCTACTGGCCAACCAGGCAGTCCAGAACATCACCTACCACTGCAAGAACAGCATCGCCTACATGGATGCTGAGAATGGAAACCTGAAGAAGGCTGTGTTGCTGCAGGGTTCCAATGATGTTGAGCTCAGGGCGGAGGGCAACAGCCGCTTCACTTTCAGCGTCCTAGAGGATGGCTGCAGTAGACACACTGGCCAGTGGAGCAAGACAGTCATTGAATACAGAACAAATAAACCATCTCGCCTTCCCATCCTCGACATTGCACCTTTGGACATTGGTGGCGCAGATCAAGAGTTTGGTTTGGACATTGGCCCAGTCTGTTTCAAATAAATAGACTCATGATAAATTAaacgagagaaagaaagaaaaaagaaaaatctctGCCCttctttctgtgtttttttatacTGAATGCTGATTTTTTTCCGCAAATCCACTTGCTTAAGCTGGGCTCTATCGGAGTGGACCAATGGACTGAACGGAGCATTGCGCAATGCAAATTAATACAGCAGCCCAAAGAGACGCGGGAGGGATAACACCATGTTATGGGACATGTCAtcattttgtaaaaattaaagaAGTGTAATAAAAAGAATGAAAGTATACATCACTTTGTGGTCTTTGTATATCTTCCAAAGAGGAAGTTTAAAACCACAATTTCCGTAAGGTTTAAACTACCTCATGTGTAAAGGAAAATAATAATCAACATCCTAGTCGTCGCTAGATGGTACTAAGGCTTCAAGTTCTGTCCTGTTTCAAAGGTGCTCCAATACTTGAAGCAGTGATATTATATGGTGCTAAACATGCAGCTGTGGAGAAAACCACTGTTACTGTATTACTTTGTATTGTCTCTAAGGAATATTGCACAGGTCCCCCTGATAATCCCATTTTTAAGCAGGTGGAATATTCCTAAACCTGATGTATGTCTGGTTTTgactttggttttttttttttttggttttgtttgttttttgttttgttttctgagaGTTTTGTTCAGATTTTTGTTTAGGCATTACATTCTTTTACGCCCCCCAGTGTTAATACTGACAGCACACTTGGTCCATTTTAAAGGGTTGCAGAGACCTCTCTCTCAAAACAAACCACAAAGTTTATTGTACCTATTTTGTATATGTGAgatgtttaaataaattgtgaaaagTTCTGAAAATAAAGCATGTCCATTGTTCCGAAACAAATTATTTCATGAGTTAAGTGCTTTAATGTTGGGAACAAAATGTCTGACTTAATTAGACATTTTGAACATCTGCCTAAATTCAATGACTTCAATGTGTTTATTGTCAAAACATGAAAtgggttttcttttttattcaatgAATGGGTGTTTGTCTTAGCAATTTTCGTTTTGGGTCTAATGCCATTAAGAGCTTCATTTCCTCTGTTTTCAGTTATGACATGCTTTTCAGATGGCAAAATCTTTCTCACTTTTGATTCAAATAAAAAGCCAGTCACTGCAACTTGGGATGCTTGCATTTGTAGAGAATACAAACATGTAGATTTTGTTTTAAGATTAAGTATTTAGCGCAGCAGATTTTTGTGCCATAAATATAATTTCTGCTACtccaaatagagctgttcaaATCGTAGTTGAAATTatgttcatattgcaatataaaccgcagcaaaaaaatatatagtaatgtACGAATTTTTCTTAATTTGACAGATTACGTCAGCTCAGATTTTTAGCCTATAGGCAATATACATCCCCACTCACACATCGGTTATAATATTGCTTTCTAAATTATTTgggagagatgtttttttttgtttttgtgactaTTTCATGTATGGATATGGTTAAAGAGAGCAAACATTTGCA

Function

symbol description
col1a2 Predicted to be an extracellular matrix structural constituent. Acts upstream of or within response to mechanical stimulus and skeletal system development. Predicted to be located in extracellular region. Predicted to be part of collagen type I trimer. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including cranium; integument; myoseptum; osteoblast; and pectoral fin. Used to study Ehlers-Danlos syndrome and osteogenesis imperfecta. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome (multiple); heart valve disease; intracranial aneurysm; osteogenesis imperfecta (multiple); and osteoporosis. Orthologous to human COL1A2 (collagen type I alpha 2 chain).

GO:

id name namespace
GO:0001501 skeletal system development biological_process
GO:0009612 response to mechanical stimulus biological_process
GO:0030198 extracellular matrix organization biological_process
GO:0031012 extracellular matrix cellular_component
GO:0005581 collagen trimer cellular_component
GO:0005584 collagen type I trimer cellular_component
GO:0005615 extracellular space cellular_component
GO:0005201 extracellular matrix structural constituent molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-8415 Predicted to be an extracellular matrix structural constituent. Acts upstream of or within response to mechanical stimulus and skeletal system development. Predicted to be located in extracellular region. Predicted to be part of collagen type I trimer. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including cranium; integument; myoseptum; osteoblast; and pectoral fin. Used to study Ehlers-Danlos syndrome and osteogenesis imperfecta. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome (multiple); heart valve disease; intracranial aneurysm; osteogenesis imperfecta (multiple); and osteoporosis. Orthologous to human COL1A2 (collagen type I alpha 2 chain).

Ensembl:

ensembl_id ENSDARG00000020007

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00028304 True 5750 mRNA 0.52 50 40983221 41002980

Neighbor

gene id symbol gene type direction distance location
XLOC_014238 CR749767.1 coding upstream 24605 40958500 ~ 40958616 (+)
XLOC_014237 zgc:85777 coding upstream 84621 40861853 ~ 40898600 (+)
XLOC_014236 gngt1 coding upstream 123753 40856534 ~ 40859468 (+)
XLOC_014235 si:ch211-120e1.1 coding upstream 148265 40832493 ~ 40834956 (+)
XLOC_014234 NA coding upstream 246237 40692428 ~ 40736984 (+)
XLOC_014240 casd1 coding downstream 3995 41006975 ~ 41034224 (+)
XLOC_014241 ppp1r9a coding downstream 72508 41075488 ~ 41160943 (+)
XLOC_014242 asb4 coding downstream 167016 41169996 ~ 41182251 (+)
XLOC_014243 NA coding downstream 184832 41187812 ~ 41191519 (+)
XLOC_014244 NA coding downstream 230828 41233808 ~ 41238528 (+)
XLOC_014230 NA non-coding upstream 650127 40328712 ~ 40333094 (+)
XLOC_014224 NA non-coding upstream 916630 40057836 ~ 40066591 (+)
XLOC_014222 BX957260.1 non-coding upstream 1013763 39927406 ~ 39969458 (+)
XLOC_014252 NA non-coding downstream 834771 41837751 ~ 41841201 (+)
XLOC_014255 NA non-coding downstream 1124943 42127923 ~ 42140654 (+)
XLOC_014257 CU896644.3 non-coding downstream 1186010 42188990 ~ 42189104 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000054_02529145_02537881 COL1A2 coding CI01000054 null 2528905 ~ 2537881 (-)
bowfin (Amia calva) AMCG00021537 col1a2,LOC107722140,LOC107667770,LOC107591591,LOC107731699 coding CM030130.1 CM030130.1 20797698 ~ 20827291 (+)