XLOC_014246 (ago2)


Basic Information

Item Value
gene id XLOC_014246
gene name ago2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 41479990 ~ 41499645 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00028315
GAAGGGACGGACGGACGGGCCACTCGGAGCTCTCGTGCTCCAGCAACTCTGCGCGCTCACTTTAATCTTACTTTTCACCTCTGTATCgatgctgttttgaaagaaaacCCAGCTCTTCCGTTACCGCATGTGTTACGTGGCATCAGAAGACCCAAAAGTGTCGGCCCGGGATTGAATTTTGCTGCAGAAAGCGATTAAAATGTATCCCATTGGAGCAGCTGGTGCTACTGAGCTGTTTCAGGGACGTCCGTCTTCAGGGTCAGATGTTTCTGCTCCCGCGTCTCCTCCAGCACCACAAGAATATGTCTTCAAACCACCTCAGCGGCCAGACTTTGGCACAATGGGTAGGACAATCAAGCTTCAGGCCAACTTCTTTGAAATGGAAATTCCCAAGTTGGAGGTTTATCATTATGAAATAGACATCAAGCCTGAGAAATGCCCACGGAGAGTTAACCGtgaAATAGTTGAGCACATGGTCCAGCACTTTAAAACGCAGATCTTTGGAGATCGAAAGCCTGTGTATGATGGGAGGAAGAATCTCTACACTGCCATGCCTTTACCCATTGGAAGAGACAAAGTGGAGCTGGAGGTCACGATTCCTGGGGAGGGAAAAGACAGGAGCTTTAAAGTCGCTATAAAGTGGATGTCCTGTGTCAGTCTGCAAGCTTTGCATGAAGCACTCTCTGGACGGCTACCAAACATCCCTTTCGAGACCATTCAGGCTCTGGATGTTGTCATGAGACATTTGCCCTCTATGAGGTACACCCCAGTCGGACGTTCATTCTTCACTCCATCGGAGGGCTGCTCTAACCCTCTTGGTGGAGGAAGAGAAGTTTGGTTTGGTTTTCATCAGTCTGTTCGGCCATCACTCTGGAAGATGATGCTCAACATTGATGTGTCTGCCACTGCGTTCTACAAAGCTCAACCCGTCATTGAATTCATGTGTGAGGTTTTGGATTTTAAAAGCATCGAAGAGCAGCAAAAGCCCTTAACAGATTCCCAAAGAGTGAAGTTTACCAAGGAGATCAAGGGTTTGAAGGTTGAAATTACTCACTGTGGACAAATGAAGAGGAAGTACAGAGTGTGTAATGTGACGAGAAGACCAGCCAGCCATCAAACGTTTCCTTTGCAGCAAGAGAATGGTCAGACCATTGAATGCACTGTCGCCCAGTACTTCAAGGATAAGTACAAACTGGTGCTTCGATACCCACATCTCCCATGTTTACAAGTTGGTCAGGAGCAGAAACACACCTACCTTCCGTTGGAGGTCTGCAACATTGTAGCCGGGCAGCGATGCATCAAGAAACTGACAGACAATCAGACCTCCACTATGATACGTGCCACAGCCAGGTCTGCGCCCGACCGTCAGGACGAGATCAGCAAACTGATGAGAAGTGCCAACTTCAATACAGATCCTTATGTGCGTGAGTTTGGAGTCATGGTAAGAGACGATATGACTGAAGTCAATGGTCGGGTTCTTCAAGCACCGTCGATTCTCTATGGTGGAAGGAACAAAGCAATAGCAACCCCAGTCCAGGGCGTGTGGGACATGAGGAACAAGCAGTTCCACACAGGGATTGAAATCAAAGTTTGGGCCATTGCCTGCTTTGCCCCACAGAGGCAGTGCACAGAACTCCTGCTGAAGGCCTTCACTGACCAGCTTCGTAAGATCTCACGTGATGCTGGGATGCCCATTCAGGGCCAGCCGTGCTTTTGCAAATATGCCCAGGGAGCAGACAGTGTGGAGCCCATGTTCAAACACCTCAAGTACACTTATCAAGGGTTACAGTTGGTGGTGGTCATCTTACCCGGCAAGACTCCTGTTTAtgCTGAGGTGAAGCGTGTTGGAGACACTGTTCTCGGCATGGCCACGCAGTGTGTCCAGGTGAAGAATGTGCAGAAGACCACACCTCAAACCCTTTCTAACCTCTGCCTCAAGATTAACGTCAAACTGGGTGGAGTCAACAACATTCTTCTTCCACAGGGCAGgCCCTTGGTGTTCCAGCAACCAGTTATCTTTTTGGGTGCAGATGTGACTCATCCACCAGCTGGAGATGGCAAGAAACCCTCAATTGCTGCTGTCGTTGGCAGTATGGATGCCCACCCAAGCAGATACTGTGCCACAGTGCGGGTGCAGCAGCACCGGCAGGACATCATTCAGGATCTGGCAACCATGGTCAGAGAGTTACTCATCCAGTTCTACAAATCCACACGCTTCAAACCAACACGCATCATCTACTACAGAGACGGCATCTCTGAAGGCCAGTTTAACCAGGTTCTACAGCATGAGCTGCTGGCTATTCGTGAGGCCTGCATCAAGCTGGAGAAAGATTATCAGCCGGGTATCACCTTCGTTGTAGTACAGAAGAGACACCACACCAGACTCTTCTGCATGGACAGGAACGAACGGGTTGGAAAGAGTGGAAACATCCCTGCTGGCACCACTGTCGACACCAAAATTACTCATCCATTCGAGTTTGACTTTTATCTTTGCAGTCATGCTGGAATTCAGGGAACCAGTAGGCCGTCCCACTATCATGTGCTGTGGGACGACAACCATTTCACCTCTGACGAGCTGCAGGTCCTCACCTACCAGCTGTGCCACACCTATGTTCGCTGCACCCGCTCGGTCTCCATTCCTGCACCAGCCTATTACGCCCACTTGGTGGCGTTTCGCGCCCGCTACCACTTGGTTGACAAAGAACATGACAGTGCTGAAGGCAGTCACACATCAGGTCAGAGTAACGGCAGAGATCAACAAGCCCTGGCCAAAGCTGTGCAGATCCACCAGGACACACTGCGCACCATGTACTTCGCCTGAACAAAGCCAGAACCAAGCCCCACAATCCTGAAAACAGCacggtgtgtgtgtatatgtgtgtgtgtgtgtgcgtgtgtgtaattttaagtgttaTACAAACGAGACCCTTCAAATGGAGACAAAATGAGGACCGCCATGCTGTTCG

Function

symbol description
ago2 Enables miRNA binding activity and pre-miRNA binding activity. Acts upstream of or within nucleate erythrocyte differentiation and pre-miRNA processing. Predicted to be located in P-body. Predicted to be part of RISC complex. Is expressed in several structures, including eye; fin; integument; intermediate cell mass of mesoderm; and pleuroperitoneal region. Orthologous to human AGO2 (argonaute RISC catalytic component 2).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0035278 miRNA mediated inhibition of translation biological_process
GO:0035279 mRNA cleavage involved in gene silencing by miRNA biological_process
GO:0043363 nucleate erythrocyte differentiation biological_process
GO:0006417 regulation of translation biological_process
GO:0031047 gene silencing by RNA biological_process
GO:0031054 pre-miRNA processing biological_process
GO:0045947 negative regulation of translational initiation biological_process
GO:0035196 production of miRNAs involved in gene silencing by miRNA biological_process
GO:0016442 RISC complex cellular_component
GO:0000932 P-body cellular_component
GO:0005845 mRNA cap binding complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0000340 RNA 7-methylguanosine cap binding molecular_function
GO:0005515 protein binding molecular_function
GO:0004518 nuclease activity molecular_function
GO:0004519 endonuclease activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0070883 pre-miRNA binding molecular_function
GO:0003723 RNA binding molecular_function
GO:0035197 siRNA binding molecular_function
GO:0035198 miRNA binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-110606-6 Enables miRNA binding activity and pre-miRNA binding activity. Acts upstream of or within nucleate erythrocyte differentiation and pre-miRNA processing. Predicted to be located in P-body. Predicted to be part of RISC complex. Is expressed in several structures, including eye; fin; integument; intermediate cell mass of mesoderm; and pleuroperitoneal region. Orthologous to human AGO2 (argonaute RISC catalytic component 2).

Ensembl:

ensembl_id ENSDARG00000061268

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00028315 True 2966 mRNA 0.50 20 41479990 41499645

Neighbor

gene id symbol gene type direction distance location
XLOC_014245 dlx6a coding upstream 12949 41419519 ~ 41467041 (+)
XLOC_014244 NA coding upstream 241462 41233808 ~ 41238528 (+)
XLOC_014243 NA coding upstream 288471 41187812 ~ 41191519 (+)
XLOC_014242 asb4 coding upstream 297739 41169996 ~ 41182251 (+)
XLOC_014241 ppp1r9a coding upstream 319047 41075488 ~ 41160943 (+)
XLOC_014247 si:ch211-57n23.1 coding downstream 10311 41509956 ~ 41513809 (+)
XLOC_014248 crtc2 coding downstream 21247 41520892 ~ 41540572 (+)
XLOC_014249 si:ch211-57n23.4 coding downstream 51690 41551335 ~ 41597464 (+)
XLOC_014250 gatad2b coding downstream 202015 41701660 ~ 41724246 (+)
XLOC_014251 tinagl1 coding downstream 269490 41769135 ~ 41829721 (+)
XLOC_014238 CR749767.1 non-coding upstream 521374 40958500 ~ 40958616 (+)
XLOC_014234 NA non-coding upstream 743006 40692428 ~ 40736984 (+)
XLOC_014230 NA non-coding upstream 1146896 40328712 ~ 40333094 (+)
XLOC_014252 NA non-coding downstream 338106 41837751 ~ 41841201 (+)
XLOC_014255 NA non-coding downstream 628278 42127923 ~ 42140654 (+)
XLOC_014257 CU896644.3 non-coding downstream 689345 42188990 ~ 42189104 (+)
XLOC_014261 BX571688.1 non-coding downstream 837672 42337317 ~ 42337431 (+)
XLOC_014264 BX950855.1 non-coding downstream 1006329 42505974 ~ 42516134 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000054_02212303_02220785 AGO2 coding CI01000054 null 2212182 ~ 2220785 (-)
bowfin (Amia calva) AMCG00021746 ago2,LOC107591597 coding CM030130.1 CM030130.1 27612761 ~ 27620292 (+)