XLOC_014329 (slc30a8)


Basic Information

Item Value
gene id XLOC_014329
gene name slc30a8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 46343385 ~ 46362232 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00028453
AAGTGACATCATGTTCACGAAAAAACCTGAAAAGATCCATTTGGTGTCGGAAAACAGTGCAAAGATGTACACCATCATGTCAGAAAGCATGCCTTCAGTTGATATGAAGGATGGTAAACACTGCCATGATAATAACCGTGCTCTGGAGGACCGAGAGCGGGAGAAGAAGATCGCCAAGAAGCGTCTGTACATCGTTTCTGCTGTGTGTCTGGTCTTTATGGTGGGAGAGATTTTAGgaggGTATTTTGCTGGCAGTCTGGCAGTGATGACGGACGCAGCTCATCTTCTAGTGGATCTCACCAGCTTCATCATCAGTCTGTGTTCGCTCTGGCTTTCCTCCAGACCTGCCACTCGTACTCTTAATTACGGCTGGCATCGAGCAGAAATCCTGGGTGCTCTCCTGTCCATCTTCACCATCTGGCTGGTGACCGGAGTGCTGGTGTATCTGGCTGTGGAGAGAATCATCAATGATAACTTCACTATTGAGGGCACAGTCATGCTCATCACCTCCGGCTGCGCTGTTCTGGCCAACATCATAATGGCTCTGACTCTGCATCAGTCTGGTCATGGACACAGTCACGGTGGTCTGAGCGCTGGACACGGACACAGCCATGATCACGGGAAAGAAAACGGACACAGCCATTCAGATGGCAGCCATCATGATGTGGAGGAGCAAAGGCCTGGGAAAACTCAAGCCAATGCTAGTGTCCGGGCGGCGTTCGTGCATGTGATTGGAGATCTGCTGCAGAGCATCAGTGTGCTCGTCAGCGCGCTCATCATCTTTTTTAAgCCTGAATATAAAATTGCAGATCCTATTTGCACCTTCCTGTTTTCCTTGTTCGTCCTGGGaaccacattcaccatcatgAGGGACATTGTTATCGTCTTGATGGAAGGCACACCAGCCGGAGTGAACTATAATGAAGTGCGTCAGCTTCTGCTGGGAGTAAAGGGTGTTAAAGCCGTGCACAACCTGCACATCTGGGCCTTGACCATGAACCAGGCTGTGCTTTCTGCTCATGTGGCCACCGATGAGACTGTGGATCCACAGGAGGTGCTTCGAGAAATGACCCAGGTCTGTTTTACCAAATACAGTTTCCATTCGGTCACCATTCAGCTGGAGCCGCAGGCCGATCAGAGACCCGACTGCAGCCTCTGTCAAGACCCCGCcaagtgaaacacacacacacacacacacacactaaagagggatagttcacccaaaaatgaatatttactcaccatttactcttcctAATGTTGGTCCAACccaaaaaaagattatttgaaaaatgctggaaaccagtagccattaacttccattgtaggaaaaaaatactattaaaaatacCATTGCcatgattatttataaaaatactatTGCCCCAGCGACTCGACCATGGATAAGCGGAGGAAAATGGATGGAAGGAAGTCCCTAACTAGATTTCCATtcaaagatgtgaattagatttatgagcaaaactggaatattgcatgaaACAAAGCCGCGTTTCCTTCCAATGAGAAACAAAAGAGACCAAAATCATTATGTCCTGATAAACAGCAAATATCAGACAGAGAAATGTAGTTTATAGTGGTAGGAGagccacttgtttttttttctccccaataAATGAGTTGCGCCTTATAATAAATAGACGAAATGCAGTGAACACAGTGTGGTGGCCTTTTAGGGGCCTGAGATgctcaacataggctcatttagAAAACGTagacctatatacatttctggagatcaggaattatgtagccagaggaacataTTGTTGCATTTCAGCTTacaaacgctacagggcggtatgacgctgttccttttcacacttaccagctgaccgcttacctccatgtagacggctttcctgctgttaccagtttgtccagtgccTCGTTGCATATGGCAGTGGACTTGATCTTGATGACTGGGTTTGAATCCAGCAGAAAACAGTCCCAGAAAgcatgtaaaacaaaaacaaacccctCAATAAAACAAgtcaataacagggtgagaatgtggtaaaatcttaaaacgtggtaaaaaccaggcgagggcttttctttttttcgtattgcttttaaaaacacgatcaattgggtttagggaaggaggagggtaggtcagttgatcagtcagacgacagtgacctctggtggatttacatggaAAAGCAGGCATGAATGAcattcgcgagagaaatttgagatctcaaaatgcgtacacagcggcctctgttggatacgcgaaaacaaaacatgcaaaaaacatagctcctgggacatatttggcgctcttcagaaatgtatacaggggtacttTTTTAAAAAGAGCTTGGGTTGGAGATGCTCTTTTGAAGCGCaaacagatgctcaagacagttctggagggaataataatagaagaagaataatactgaagcactgtgatggcGGACTGACGGAGTGCTGAGGCCTTTTACAATCAGAAAAAtgacatttcagatattttacaatgcTGGAAACATGTAAAGCTGCAAACTTTATTAATGCAAAGACTCTGAACACACACGTTTATATCGGTGAAAAACTAAATCACATCACGCATACTGATGAAGAGCATGCACATTTAAAtattgtgtttattcatttaatctgTTTACATCATTTGTCATGCACATTTTATCTTATCAAATATacagtttatcctactcagttgtgctCGTaactttttatgcacatttttaaaatgcatgcacATCTTAGTGTTTCCATTAAGCATTTGTATACAATATTTCACAATGCACATGAAAATAGGCGGATGTAAACAACAACAGGTAGATAAAAACAGCTAATGGCTACCAGTTTTTGGattattttctaaatatctttttttttgtctatgaATGATGACACGATttgaatttttgtgtgaactaccccttaaaaGAAGAGCCCAAAGGGACAAAAGAGCCACAAACAGAGCATTTCGAGAGGATTATCATTGTGTTGGTCATGTTTTATAACTATAGTTTTATTCTAGGAGGAGGACTTCTTagactttgtattatttttggggtttttttgtcACATTATTTAGTGTTTGGTTGCATTATTATCTTGAGAATGGGATATAAGTAGTATACAATGCAAAATATTTTCATCTtaatttcggtaacactttacaataaggtttattagttaatgcatttactaacatgaattaatcatgaacaacacatgtacagcatttattaatcataatgtaacatttactaatgcattattaacatccaagtccatgcttgttaacattagttaatgcaccgttaactaacaatgaactactgtattttcattaactaacgttaactaacatgaacaaatacagtactagatgtattgttcattgtttgttcatgttagtaaatgcattaattaacattaatgaaccttattgtaaagtgtgagctTATTTTCTGCTATGGTTATGACAAAGCTGCTTGTTTTAAATCTCTTTGCATGAACAGACCTGCTATTCAGGGGAAAGAATGATTCGATTAAGATGTATTAATGATGAAAATGaactatttattataaataatagacATATAGATTTAaagattgatttgtttttctaaATGAGTGTTTTATTGGGATCTGTgttattatatgtgtgtgtttgatcacATGACCTCTTCACTGAGAGTGATGCATTATTATATATGGTAGAAGTACATGCAAAGTATTGTATTCAGAATTTCTGCCATGATTATGACACAGCAGCTTGTTTTTAATCTCTTATTATTAGCAGAATCATTAGTGAGggctaaaaataatgtttaatt
>TCONS_00028454
ATCATGTTCACGAAAAAACCTGAAAAGATCCATTTGGTGTCGGAAAACAGTGCAAAGATGTACACCATCATCATGCCTTCAGTTGATATGAAGGATGGTAAACACTGCCATGATAATAACCGTGCTCTGGAGGACCGAGAGCGGGAGAAGAAGATCGCCAAGAAGCGTCTGTACATCGTTTCTGCTGTGTGTCTGGTCTTTATGGTGGGAGAGATTTTAGgaggGTATTTTGCTGGCAGTCTGGCAGTGATGACGGACGCAGCTCATCTTCTAGTGGATCTCACCAGCTTCATCATCAGTCTGTGTTCGCTCTGGCTTTCCTCCAGACCTGCCACTCGTACTCTTAATTACGGCTGGCATCGAGCAGAAATCCTGGGTGCTCTCCTGTCCATCTTCACCATCTGGCTGGTGACCGGAGTGCTGGTGTATCTGGCTGTGGAGAGAATCATCAATGATAACTTCACTATTGAGGGCACAGTCATGCTCATCACCTCCGGCTGCGCTGTTCTGGCCAACATCATAATGGCTCTGACTCTGCATCAGTCTGGTCATGGACACAGTCACGGTGGTCTGAGCGCTGGACACGGACACAGCCATGATCACGGGAAAGAAAACGGACACAGCCATTCAGATGGCAGCCATCATGATGTGGAGGAGCAAAGGCCTGGGAAAACTCAAGCCAATGCTAGTGTCCGGGCGGCGTTCGTGCATGTGATTGGAGATCTGCTGCAGAGCATCAGTGTGCTCGTCAGCGCGCTCATCATCTTTTTTAAgCCTGAATATAAAATTGCAGATCCTATTTGCACCTTCCTGTTTTCCTTGTTCGTCCTGGGaaccacattcaccatcatgAGGGACATTGTTATCGTCTTGATGGAAGGCACACCAGCCGGAGTGAACTATAATGAAGTGCGTCAGCTTCTGCTGGGAGTAAAGGGTGTTAAAGCCGTGCACAACCTGCACATCTGGGCCTTGACCATGAACCAGGCTGTGCTTTCTGCTCATGTGACTGTGGATCCACAGGAGGTGCTTCGAGAAATGACCCAGGTCTGTTTTACCAAATACAGTTTCCATTCGGTCACCATTCAGCTGGAGCCGCAGGCCGATCAGAGACCCGACTGCAGCCTCTGTCAAGACCCCGCcaagtga

Function

symbol description
slc30a8 Predicted to enable zinc ion transmembrane transporter activity. Acts upstream of or within glucose homeostasis and type B pancreatic cell development. Predicted to be located in transport vesicle membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to several human genes including RPRD1A (regulation of nuclear pre-mRNA domain containing 1A).

GO:

id name namespace
GO:0006882 cellular zinc ion homeostasis biological_process
GO:0071577 zinc ion transmembrane transport biological_process
GO:0031018 endocrine pancreas development biological_process
GO:0055085 transmembrane transport biological_process
GO:0042593 glucose homeostasis biological_process
GO:0006812 cation transport biological_process
GO:0009749 response to glucose biological_process
GO:0006829 zinc ion transport biological_process
GO:0061088 regulation of sequestering of zinc ion biological_process
GO:0030073 insulin secretion biological_process
GO:0010043 response to zinc ion biological_process
GO:0003323 type B pancreatic cell development biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008324 cation transmembrane transporter activity molecular_function
GO:0005385 zinc ion transmembrane transporter activity molecular_function

KEGG:

id description
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-060315-10 Predicted to enable zinc ion transmembrane transporter activity. Acts upstream of or within glucose homeostasis and type B pancreatic cell development. Predicted to be located in transport vesicle membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to several human genes including RPRD1A (regulation of nuclear pre-mRNA domain containing 1A).

Ensembl:

ensembl_id ENSDARG00000100917

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00028453 False 3839 mRNA 0.40 8 46343385 46362232
TCONS_00028454 True 1149 mRNA 0.51 8 46343392 46359570

Neighbor

gene id symbol gene type direction distance location
XLOC_014328 rprd1a coding upstream 9575 46309553 ~ 46333810 (+)
XLOC_014327 mapk15 coding upstream 39763 46240171 ~ 46303622 (+)
XLOC_014326 vps28 coding upstream 104761 46222428 ~ 46238624 (+)
XLOC_014325 NA coding upstream 124345 46216335 ~ 46219040 (+)
XLOC_014324 cap2 coding upstream 132481 46158078 ~ 46210904 (+)
XLOC_014330 med30 coding downstream 9883 46372115 ~ 46411358 (+)
XLOC_014331 NA coding downstream 60859 46423091 ~ 46438135 (+)
XLOC_014332 AL953858.1 coding downstream 462491 46824723 ~ 46825683 (+)
XLOC_014333 si:ch211-229b6.1 coding downstream 773445 47135677 ~ 47137425 (+)
XLOC_014334 NA coding downstream 826298 47188530 ~ 47191501 (+)
XLOC_014321 NA non-coding upstream 249733 46091317 ~ 46093652 (+)
XLOC_014317 NA non-coding upstream 615323 45727214 ~ 45728062 (+)
XLOC_014316 CT737154.1 non-coding upstream 834404 45508865 ~ 45508981 (+)
XLOC_014315 NA non-coding upstream 977658 45359277 ~ 45365727 (+)
XLOC_014337 CU138512.1 non-coding downstream 944391 47306623 ~ 47306738 (+)
XLOC_014339 NA non-coding downstream 975350 47337582 ~ 47338157 (+)
XLOC_014341 NA non-coding downstream 1075972 47438204 ~ 47448594 (+)

Expression


Co-expression Network