Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_014452 |
| gene name | edn1 |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007130.7 |
| NCBI id | CM002903.2 |
| chromosome length | 48449771 |
| location | 3376430 ~ 3381422 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| edn1 | Predicted to enable endothelin A receptor binding activity; endothelin B receptor binding activity; and hormone activity. Acts upstream of or within several processes, including anterior lateral line neuromast development; face morphogenesis; and skeletal system development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; ectoderm; mesoderm; neural crest; and pharyngeal arch. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bronchial disease (multiple); obesity; obstructive sleep apnea; and rheumatoid arthritis. Orthologous to human EDN1 (endothelin 1). |
| id | name | namespace |
|---|---|---|
| GO:0019229 | regulation of vasoconstriction | biological_process |
| GO:0060349 | bone morphogenesis | biological_process |
| GO:0060351 | cartilage development involved in endochondral bone morphogenesis | biological_process |
| GO:0003100 | regulation of systemic arterial blood pressure by endothelin | biological_process |
| GO:0014826 | vein smooth muscle contraction | biological_process |
| GO:0051216 | cartilage development | biological_process |
| GO:0009953 | dorsal/ventral pattern formation | biological_process |
| GO:0048899 | anterior lateral line development | biological_process |
| GO:0048901 | anterior lateral line neuromast development | biological_process |
| GO:0014033 | neural crest cell differentiation | biological_process |
| GO:1904888 | cranial skeletal system development | biological_process |
| GO:0060536 | cartilage morphogenesis | biological_process |
| GO:0048703 | embryonic viscerocranium morphogenesis | biological_process |
| GO:0060585 | positive regulation of prostaglandin-endoperoxide synthase activity | biological_process |
| GO:0006874 | cellular calcium ion homeostasis | biological_process |
| GO:0060325 | face morphogenesis | biological_process |
| GO:0005576 | extracellular region | cellular_component |
| GO:0005615 | extracellular space | cellular_component |
| GO:0005179 | hormone activity | molecular_function |
| GO:0031707 | endothelin A receptor binding | molecular_function |
| GO:0031708 | endothelin B receptor binding | molecular_function |
| id | description |
|---|---|
| ko04668 | TNF signaling pathway |
| ko04066 | HIF-1 signaling pathway |
| ko04024 | cAMP signaling pathway |
| ko04080 | Neuroactive ligand-receptor interaction |
| ko04926 | Relaxin signaling pathway |
| ko04916 | Melanogenesis |
| ko04924 | Renin secretion |
| ko04270 | Vascular smooth muscle contraction |
| ko05200 | Pathways in cancer |
| ko05418 | Fluid shear stress and atherosclerosis |
| ko05410 | Hypertrophic cardiomyopathy |
| ko04933 | AGE-RAGE signaling pathway in diabetic complications |
| id | description |
|---|---|
| ZDB-GENE-000920-1 | Predicted to enable endothelin A receptor binding activity; endothelin B receptor binding activity; and hormone activity. Acts upstream of or within several processes, including anterior lateral line neuromast development; face morphogenesis; and skeletal system development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; ectoderm; mesoderm; neural crest; and pharyngeal arch. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bronchial disease (multiple); obesity; obstructive sleep apnea; and rheumatoid arthritis. Orthologous to human EDN1 (endothelin 1). |
| ensembl_id | ENSDARG00000036912 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00028608 | True | 1220 | mRNA | 0.43 | 5 | 3376430 | 3381422 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_014451 | si:ch211-133n4.9 | coding | downstream | 72435 | 3300795 ~ 3303995 (-) |
| XLOC_014450 | si:ch211-133n4.7 | coding | downstream | 78078 | 3290098 ~ 3298352 (-) |
| XLOC_014449 | si:ch211-133n4.10 | coding | downstream | 89037 | 3285305 ~ 3287393 (-) |
| XLOC_014448 | illr2 | coding | downstream | 97655 | 3275361 ~ 3278775 (-) |
| XLOC_014447 | illr3 | coding | downstream | 103432 | 3266914 ~ 3272998 (-) |
| XLOC_014453 | hivep1 | coding | upstream | 1603 | 3383025 ~ 3488860 (-) |
| XLOC_014454 | tmem170b | coding | upstream | 158179 | 3539601 ~ 3574060 (-) |
| XLOC_014455 | NA | coding | upstream | 220602 | 3602024 ~ 3714913 (-) |
| XLOC_014456 | smim13 | coding | upstream | 336566 | 3717988 ~ 3726781 (-) |
| XLOC_014457 | btr22 | coding | upstream | 347586 | 3729008 ~ 3790595 (-) |
| XLOC_014711 | CR382300.3 | misc | upstream | 16347268 | 19728690 ~ 19728755 (-) |
| XLOC_014437 | NA | non-coding | downstream | 456774 | 2916941 ~ 2919656 (-) |
| XLOC_014430 | NA | non-coding | downstream | 604742 | 2673751 ~ 2771688 (-) |
| XLOC_014434 | NA | non-coding | downstream | 614275 | 2756239 ~ 2762155 (-) |
| XLOC_014432 | NA | non-coding | downstream | 639395 | 2727176 ~ 2737035 (-) |
| XLOC_014428 | NA | non-coding | downstream | 927823 | 2432847 ~ 2448607 (-) |
| XLOC_014459 | CT030005.2 | non-coding | upstream | 378756 | 3760178 ~ 3761403 (-) |
| XLOC_014474 | CU570886.1 | non-coding | upstream | 822823 | 4204245 ~ 4204359 (-) |
| XLOC_014475 | NA | non-coding | upstream | 1065331 | 4446753 ~ 4449906 (-) |
| XLOC_014476 | CT583670.1 | non-coding | upstream | 1099761 | 4481183 ~ 4481297 (-) |
