XLOC_014861 (e2f3)



Basic Information


Item Value
gene id XLOC_014861
gene name e2f3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 29274385 ~ 29294457 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00029327
TCGCGCGTAAACCTCATCCCCTACTTCATTGTCCGCTTCCTGGAGCCATTTTTCGCTGAAGCAAGAGCGAGATCGCATCGCTTTTTAATCGCTTACATCGGGTGTTTTATCCTTTAGCAATTGCACTCATATTACAGCTATGCATTCCTAGCACTGTCCGCTACCATCATTTATGATCATTTTACACCCACTCGCCCGGATTTGGTAGAAAACTAGCTTCAAATCACAAGTGGGACAAAGGGAACCTGCGCCTCTGAGGATCATGAGAAAGGGGGGTTCCTCGGTCCCAGGACAAGTCATGTTGACAGGGGTTGTTAGAGCTGAACAGCACGGTGTTTTTACTGCGGTTTCCGATCGACGGTGTGCAGTTTATTCCAATGCTACCCGTATACAAATAAACACACCGCCGTCCACTAATAACGGCTGTGTGCCCGAGGCTTCTGCTGACAGTTTGTACACAACTCCTCTACAAGGATCCACACATGGGACAGGACTGCGACCCACGTTAGGACGACCACCGGCTAAAAGGAGGCTGGAGCTCGACATCACAGACCACCAATACAGTGAGCCAGCTAAAACTCTTCGAAGTCGCAAAGGAGCTCTTAAACTGAAGATTCCCAAAGCCCCCAAAACCCCACCGGAGAAGACTCGATACGACACATCCTTGGGCTTCTTAACTAAAAAGTTTTGTCAGCTTCTGGCGCAGTCCTCTGATGGAGTATTGGATCTCAATAAAGCTGCCATTGTACTCAACGTCCAGAAGCGACGTCTGTATGACATCACCAACGTGCTGGAGGGAGTGCGCCTCATCAAGAAAAAGTCAAAGAACAACATACAATGGCTGGGCTCCAGCCTGCCATCAGACGGTGGGCTTCCATCTCCAGCAATGCAGAGTCACAGCCTGGCCAGAGAGATGCTGGCGCTCACTCAGGAGGAGAGACGTCTGGATGAGCTCATACAGACCTGTACGAGGAACGTCCAGCAGATGACAGAGGAGATCCACAGTCAGAAATATGCCTATGTGACCTATCAAGACATTCGAAGGATAAAAAGCCTAAAAGATCAAACCGTCATAGCGATTAAAGCACCCTCTGAAACGAAGCTGGAAGTGCCTGATCCAAAGGAGAGTTTACAGGTACACCTGAGTAGCTCGAAGGGTCCTATTGATGTCTTCCTCTGTACGGACGGTGGTGACTCTGGAAGTCCACTACAGAATGGGCTGGATGTAAATGGAAATCACCCTGCGTTTCTCAAAGTCTCCCAAGAAGCTGCTTCAGATGGACCGGCTGATAATGTGAAGATGAACGGCAACTCTAATGCCAGCGTCAATGGTTTTGGGCCAGTGTCTGGAAATGCCCCCATGTCACCCCTCAGTTCCTCCTTGTCCTCCATTCTCCAACAGCCAGAGGAGGCGATCCCCTTCGTGCCTCTGTCTCCTGCTCTCCTCAGCGACGAATACATGCTGGGCTTGGGAGATGAGCAGGGTATTAGTGATCTGTTTGACTCCTGTGACCTGGACACGCTAGCACTGGATGACCTCCTTAGGATATGAGTGACCCCGGAGTCCTGCTTTTCAAGTTAGTCGACCAGTTATTTTTGCATCCTGAATGAAATCTGAATTGACAAAAATGacacgtgtgaattttgaggacAAACTACAGACTGAATTTCGTTTTTCCCTCGTTGTCACATTTGAAATTCAGAGTTTACGCTTGAAACTCAAGTTTTACCACTAAGGGATTCAAAGTTTCTCTTGTCTGATACTGTAAAGATGAGTTTCTGTACATGgataatgttttaaaagtaattttttagtGTGGTGAATTGCATGAGTTGTGTGAGTGTCTATCAACTTTGTCATACTGGTCTTTGTGCTCTCAACAAATATATCGCAGAAAGGTCACAATATAGAGTATCTCTCTAATGTCAATgtgatcatttttgtttgttgagTTATTCTTGCTTGCTTTTCAAATGGAAAAAGGAAGTGTCTTAGCATTATAGGCTAGCTAAAAATCAAAGAATACTGTACCCTTATTGATTGATCGATCCAAAGTGCATTTGTTGCATCATTTTGTATTTCACTCTAGCATTTGCACAGATCAAGGTGTGAGAGCTATGTTGTGATCTGTCTAGTGATGTGTGGATATATGTAGAATCAAATCTGTTTGACAGTGTCTTATCACTTTGTTACCAAATGGTCTGGGCAAATTTGAACATGCCTGTGTTAACAATGAAATGCTTCTGTGAGTTCTCATTTATTAAAGTTTGTACAACTTTTAGATTGGAAATGACCCTAATGTAGTCCCCTCAATGTTGAATGTATTTCAGTATCTGAATTGCACTGAAGTCTTAAAGCCATGATGGACGTCTGTGGCAAAACTTGCCCCAATGATGTAACATTTAGTGTCCCACAGAGAATTTTAAGGTTTTTCAGTAGCaggattgttttgtttgtaaaatcAGATATTTCCCCCCTCAGTTTTGTCCATTCCAATAAATTAATCATTATACAAAGGCTGcctaaataatgtaaaatgatttattcctcttttttttctttatataccTTAAGTCCTGCAAAATAGATTAAGCCAATTTGttactttagttttatttctgtAACTTTTAGGTAAGTTCAGTTGTTTAATACTTCAAATTTGAAGTAACTTGTTAATGCAGTTTTTGCTGTGGTTAAAGTAAATTATGGTACTTAATTATGAATTAGTGCTAATGCTCACTAGTTCTTTTGGTTCTGCATAGGAATGAGGGTATTGGTCATATAGAACAATGTTATGAGTAATCTATTTGCCAGTATGTGTTCTATTCTATACAGTGCAAATTTCGGATATTCTATCCTAAATGtagatttgattttctttttttatatatatataattaggcaGTTTTGTGTGCCAACGTGTgtgaaaatgtaaagttttatatATGTGGATTGTAAACTGCTCATCTGTTTTTTgcaaaattgtttttaataaagttaTGAATTTCTGCA
>TCONS_00029328
TCGCGCGTAAACCTCATCCCCTACTTCATTGTCCGCTTCCTGGAGCCATTTTTCGCTGAAGCAAGAGCGAGATCGCATCGCTTTTTAATCGCTTACATCGGGTGTTTTATCCTTTAGCAATTGCACTCATATTACAGCTATGCATTCCTAGCACTGTCCGCTACCATCATTTATGATCATTTTACACCCACTCGCCCGGATTTGGTAGAAAACTAGCTTCAAATCACAAGTGGGACAAAGGGAACCTGCGCCTCTGAGGATCATGAGAAAGGGGGGTTCCTCGGTCCCAGGACAAGTCATGTTGACAGGGGTTGTTAGAGCTGAACAGCACGGTGTTTTTACTGCGGTTTCCGATCGACGGTGTGCAGTTTATTCCAATGCTACCCGTATACAAATAAACACACCGCCGTCCACTAATAACGGCTGTGTGCCCGAGGCTTCTGCTGACAGTTTGTACACAACTCCTCTACAAGGATCCACACATGGGACAGGACTGCGACCCACGTTAGGACGACCACCGGCTAAAAGGAGGCTGGAGCTCGACATCACAGACCACCAATACAGTGAGCCAGCTAAAACTCTTCGAAGTCGCAAAGGAGCTCTTAAACTGAAGATTCCCAAAGCCCCCAAAACCCCACCGGAGAAGACTCGATACGACACATCCTTGGGCTTCTTAACTAAAAAGTTTTGTCAGCTTCTGGCGCAGTCCTCTGATGGAGTATTGGATCTCAATAAAGCTGCCATTGTACTCAACGTCCAGAAGCGACGTCTGTATGACATCACCAACGTGCTGGAGGGAGTGCGCCTCATCAAGAAAAAGTCAAAGAACAACATACAATGGCTGTGGGTTACTAACAGACTTGCGGTTcacattagggctgcatgatattggggaATGATTGATTAGTccgatatttagtttttttttcaaattacggGTTATTTTTATGTTATGGTATGAAAATATGCAGGTAGTATTGACATGTTACTTGAAGAGTTCTAAATGGAAAGGATAAATATCTTTAAATTAAGAAAATTTCACAAGATAGAGGTCTgattaggggtgtgaacctacactgatCTCAAGGtttggttatgattatcatgccatcgacttggttcaattcgatatctcggtgcattggggatgctttccataaacaatttTATATATTACTTGGCAACACaataattgtatgtatttttttgtaaatttacattttatatattatttgtgatACAATTTTGTCTATTAATACAAGcggtcagatatatgaactgtaagctaaaaaaacaaaaacaaaaaaaaaacactctttttgaatgttttaaaactaaagtcCAAAAACAAagtgagcatttatagcaaataaactaattgtAATAACTAATTGTGCACAGCTATCTGCTTAAATAGTTGGAGCGTTTTAATTACTCATGGTTTCCTCCCTTGCTATAGTAAGCCACCGCCATATAACACAAATGTAGTAAATGATGTCTGTACAAAttaactggttatgattattgCTAAACCAATACCAAATTGTTtgtgtctgcatcgcggtgcatcaAAGTAACAATTACTTTTTACATCCCTATCGAATTATAAAgtgttttgtcatttttggggAAAAAAGATTGTTTTTGTATGGTTGTAAAACGTGGATAAGATGTGCATTGCAAATATACCAAATTGCTGTAA

Function


symbol description
e2f3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in liver. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human E2F3 (E2F transcription factor 3).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0051726 regulation of cell cycle biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0090575 RNA polymerase II transcription regulator complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0008134 transcription factor binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
ko04110 Cell cycle
ko04218 Cellular senescence
ko05200 Pathways in cancer
ko05206 MicroRNAs in cancer
ko05212 Pancreatic cancer
ko05225 Hepatocellular carcinoma
ko05226 Gastric cancer
ko05214 Glioma
ko05220 Chronic myeloid leukemia
ko05218 Melanoma
ko05219 Bladder cancer
ko05215 Prostate cancer
ko05224 Breast cancer
ko05222 Small cell lung cancer
ko05223 Non-small cell lung cancer
ko05166 Human T-cell leukemia virus 1 infection
ko05161 Hepatitis B
ko05160 Hepatitis C
ko05163 Human cytomegalovirus infection
ko05167 Kaposi sarcoma-associated herpesvirus infection
ko05169 Epstein-Barr virus infection
ko04934 Cushing syndrome
ko01522 Endocrine resistance
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-070112-882 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in liver. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human E2F3 (E2F transcription factor 3).

Ensembl:

ensembl_id ENSDARG00000070463

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00029327 False 3013 mRNA 0.42 7 29274385 29294457
TCONS_00029328 True 1702 mRNA 0.40 3 29290321 29294457

Neighbor


gene id symbol gene type direction distance location
XLOC_014860 NA coding downstream 3359 29202043 ~ 29271026 (-)
XLOC_014859 NA coding downstream 86249 29186529 ~ 29188136 (-)
XLOC_014858 NA coding downstream 152160 29103407 ~ 29122225 (-)
XLOC_014857 NA coding downstream 243586 28922544 ~ 29030799 (-)
XLOC_014856 NA coding downstream 449995 28817621 ~ 28824390 (-)
XLOC_014862 srfbp1 coding upstream 1734 29296191 ~ 29303788 (-)
XLOC_014863 fndc5b coding upstream 89029 29383486 ~ 29437109 (-)
XLOC_014864 NA coding upstream 455871 29750328 ~ 29796288 (-)
XLOC_014865 CU861666.1 coding upstream 490638 29785095 ~ 29785212 (-)
XLOC_014866 eif3i coding upstream 528043 29822500 ~ 29832876 (-)
XLOC_014711 CR382300.3 misc downstream 9545630 19728690 ~ 19728755 (-)
XLOC_014869 NA non-coding upstream 619892 29914349 ~ 29915967 (-)
XLOC_014870 BX547939.1 non-coding upstream 852913 30147370 ~ 30300852 (-)
XLOC_014871 NA non-coding upstream 1018388 30312845 ~ 30316143 (-)

Expression



Co-expression Network