XLOC_014873 (agr2)



Basic Information


Item Value
gene id XLOC_014873
gene name agr2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 30400372 ~ 30404096 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00029345
CTCATCAAGATGCTCAAAGGATTACTGTCAGTGCTCTTGGTCATGGTGGCCTTGTCATCCGCCTTGGGGAAGCCTGAGAAAACCACTCCAAAGAAGGAGAAGGAAAAGAGAGTTCCACAGACTCTCTCCAGAGGATGGGGTGATCAGCTGATTTGGGCACAGACATACGAGGAAGCTCTGTTTTGGTCACGATCCAAgAACAAGCCCCTCATGGTCATCTTTCACCTGGAAGACTGTCCACACAGCCAGGCTCTGAAGAAAGCATTTGCTGAGGATAAAGAAATCCAGAAGTTGGCTGATGAAGACTTTGTGATCTTGAACTTGGTGtacgaAACCACAGATAAGCACTTGTCTCCTGATGGCCAGTACGTTCCCAGAATCATCTTTGTTGATCCCTCCATGACGGTTCGGGCGGACATCACCGGCCGCTACTCAAACCGAATGTACGCCTATGAACCGGCCGACATGAAACTCTTGTTGAGCAACATGCAAAGAGCCCTGAAGTTTCTGAAGACCGAGTTGTGAACACAAACGCCTAATCTTTTCGTCCGACGAGAGGATTTGACTTCCCTGAGGGCTGTTATTACTTTGTCATTTGTTTACTGACGGCATGAAACGCACTGTAAAATCCTGTACAAATACACTGAAGTACGTTCTTTAAACACATTCTGTTACGGTTAACCTTCAGTgtttcattttcatgttttttttcaataaatgaaGTTATTCGAAAgacgtctgtctgtctatgtacgTTTGTAGTTTATTCAAATCAGCAGCATCTGCCTGTCGTGTGTGCTTTTCCAGTTAACGGAGTCTCCGGTTAATATCCTGGTGGGCGGAGTCTAATTATAACTAGCagtgaatgtgttttttttccaggCATGTCTGTCGCCTGGTTCCTAGCAGCCTTTGTTATAACCACAGAGCGTGTCAGTGTTTGATTGGTTTGAAGTTGGAGGAAGTTTCATTCCTGAAATGCTCCATTAGGCTGGAATGGGATTTGAAACAATGAAAGCATTAGCACTGTGGGAACTTGACTATTAAATTATAGCCTGGCTAAATTACAACTTTGTGGTCAGTCTTTTTTATGGCATATGGTGTCTTTATATTTCATTAgcttttgtttgtatgtttatacaTTGATTTGTAACTTAAATATAATGCATgctaaaacattaatataacattgtaataatattattaacctAATTTACTATAGGTAAATGCTCTCTtgataaaaacagattttaattgttaattgtaAATTATTCTTTATGCATCCTACATTTCACAAGTAGAATggctggaaaatgaaaaattccgaatgtaatataaacaaaatcaGGAACGcacacacatagggctcaacctgtgcagtgcacatgcccttcttagtcttggatagaaagtgacATTCCAAAATTATCTGAAGTGCCCCCGCATCTCCACCGGTCCCACCTCCCGCTCTTGAGTTCAGGttgtgctttacataaacaagaccaaaaaaaaaaactaaacacaacaaataaaaatggttaaaaacggattaaatgtgtaaaaatgtgaTCAAAATGCAAACATCTAAACTATAAACCCTATAAATGAATTATGGAATGGCATACTGGAGCTTgtatattttatgaaattatgCTTGTATaaactcactggtcactttattagggacaccttactagtaccgggttggacccccttttgccttcagaactgccctaatccttcatggcagagattcaacaagctgctggaaatattcctcagagattttgctccgtattgacatgatagcacagatttgtcagctgcacattcatgatgcgaatctcccattccaccacatcccaaaggtgctctattggattgagatctggtgactgtggaggcctttgaatacagtgaactcattgtcatgttcaagaagtaAATCTGAGATAATTttcactttatgacatggcatgttatcctgttggaagtagccatcagaagattggtacactgtggtcataaagggacggacatggtcggcaacaatattcaggtaggctgtggtgttgacatgatgctcaattggtactaatgggcccaaagtgtgccaagacaaTGTCCGACACatcagtggttatttgagttactgttgcctttctattagctcgaaccagtctggccattctcctctgacctctggcatcaacaaggcatttgcgcccacagaactgcggct
>TCONS_00029346
GCAAAAGCCGGACCAGGAGTTTGAGCCTGAACAAGCGCAGCAGGGAAATTCAGCACAGCTCATCAAGATGCTCAAAGGATTACTGTCAGTGCTCTTGGTCATGGTGGCCTTGTCATCCGCCTTGGGGAAGCCTGAGAAAACCACTCCAAAGAAGGAGAAGGAAAAGAGAGTTCCACAGACTCTCTCCAGAGGATGGGGTGATCAGCTGATTTGGGCACAGACATACGAGGAAGCTCTGTTTTGGTCACGATCCAAgAACAAGCCCCTCATGGTCATCTTTCACCTGGAAGACTGTCCACACAGCCAGGCTCTGAAGAAAGCATTTGCTGAGGATAAAGAAATCCAGAAGTTGGCTGATGAAGACTTTGTGATCTTGAACTTGGTGtacgaAACCACAGATAAGCACTTGTCTCCTGATGGCCAGTACGTTCCCAGAATCATCTTTGTTGATCCCTCCATGACGGTTCGGGCGGACATCACCGGCCGCTACTCAAACCGAATGTACGCCTATGAACCGGCCGACATGAAACTCTTGTTGAGCAACATGCAAAGAGCCCTGAAGTTTCTGAAGACCGAGTTGTGAACACAAACGCCTAATCTTTTCGTCCGACGAGAGGATTTGACTTCCCTGAGGGCTGTTATTACTTTGTCATTTGTTTACTGACGGCATGAAACGCACTGTAAAATCCTGTACAAATACACTGAAGTACGTTCTTTAAACACATTCTGTTACGGTTAACCTTCAGTgtttcattttcatgttttttttcaataaatgaaGTTATTCGAAAgacgtctgtctgtctatgtacgTTTGTAGTTTATTCAAATCAGCAGCATCTGCCTGTCGTGTGTGCTTTTCCAGTTAACGGAGTCTCCGGTTAATATCCTGGTGGGCGGAGTCTAATTATAACTAGCagtgaatgtgttttttttccaggCATGTCTGTCGCCTGGTTCCTAGCAGCCTTTGTTATAACCACAGAGCGTGTCAGTGTTTGATTGGTTTGAAGTTGGAGGAAGTTTCATTCCTGAAATGCTCCATTAGGCTGGAATGGGATTTGAAACAATGAAAGCATTAGCACTGTGGGAACTTGACTATTAAATTATAGCCTGGCTAAATTACAA

Function


symbol description
agr2 Predicted to enable identical protein binding activity. Acts upstream of or within intestinal epithelial cell differentiation. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including digestive system; hatching gland; integument; olfactory system; and vestibuloauditory system. Orthologous to several human genes including AGR2 (anterior gradient 2, protein disulphide isomerase family member).

GO:

id name namespace
GO:0010811 positive regulation of cell-substrate adhesion biological_process
GO:0060548 negative regulation of cell death biological_process
GO:0060575 intestinal epithelial cell differentiation biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005576 extracellular region cellular_component
GO:0042803 protein homodimerization activity molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-050417-214 Predicted to enable identical protein binding activity. Acts upstream of or within intestinal epithelial cell differentiation. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including digestive system; hatching gland; integument; olfactory system; and vestibuloauditory system. Orthologous to several human genes including AGR2 (anterior gradient 2, protein disulphide isomerase family member).

Ensembl:

ensembl_id ENSDARG00000070480

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00029345 False 2242 mRNA 0.41 7 30400372 30403922
TCONS_00029346 True 1128 mRNA 0.45 8 30401544 30404096

Neighbor


gene id symbol gene type direction distance location
XLOC_014872 NA coding downstream 41313 30347509 ~ 30359059 (-)
XLOC_014871 NA coding downstream 84229 30312845 ~ 30316143 (-)
XLOC_014870 BX547939.1 coding downstream 99520 30147370 ~ 30300852 (-)
XLOC_014869 NA coding downstream 484405 29914349 ~ 29915967 (-)
XLOC_014868 kpna6 coding downstream 512743 29861859 ~ 29887629 (-)
XLOC_014874 ppp1r10 coding upstream 4221 30408317 ~ 30422239 (-)
XLOC_014875 abcf1 coding upstream 24817 30428913 ~ 30447743 (-)
XLOC_014876 NA coding upstream 65874 30469970 ~ 30470501 (-)
XLOC_014877 bag6l coding upstream 71185 30475281 ~ 30510930 (-)
XLOC_014878 hpcal4 coding upstream 113215 30517311 ~ 30565122 (-)
XLOC_014711 CR382300.3 misc downstream 10671617 19728690 ~ 19728755 (-)
XLOC_014864 NA non-coding downstream 604084 29750328 ~ 29796288 (-)
XLOC_014879 NA non-coding upstream 188223 30592319 ~ 30623732 (-)
XLOC_014880 NA non-coding upstream 316916 30721012 ~ 30722504 (-)
XLOC_014883 NA non-coding upstream 427094 30831190 ~ 30835097 (-)
XLOC_014885 BX927219.1 non-coding upstream 558627 30962723 ~ 30965661 (-)

Expression



Co-expression Network