Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_014893 |
| gene name | tdp2b |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007130.7 |
| NCBI id | CM002903.2 |
| chromosome length | 48449771 |
| location | 31568992 ~ 31576321 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| tdp2b | Enables DNA binding activity and tyrosyl-DNA phosphodiesterase activity. Acts upstream of or within convergent extension involved in gastrulation; determination of left/right symmetry; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in nucleus. Predicted to be active in PML body and cytoplasm. Is expressed in Kupffer's vesicle; forerunner cell group; and tail bud. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 23. Orthologous to human TDP2 (tyrosyl-DNA phosphodiesterase 2). |
| id | name | namespace |
|---|---|---|
| GO:0006302 | double-strand break repair | biological_process |
| GO:0006974 | cellular response to DNA damage stimulus | biological_process |
| GO:0007275 | multicellular organism development | biological_process |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | biological_process |
| GO:0007368 | determination of left/right symmetry | biological_process |
| GO:0007369 | gastrulation | biological_process |
| GO:0060027 | convergent extension involved in gastrulation | biological_process |
| GO:0006281 | DNA repair | biological_process |
| GO:0005634 | nucleus | cellular_component |
| GO:0005654 | nucleoplasm | cellular_component |
| GO:0016605 | PML body | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0070259 | tyrosyl-DNA phosphodiesterase activity | molecular_function |
| GO:0070260 | 5'-tyrosyl-DNA phosphodiesterase activity | molecular_function |
| GO:0030145 | manganese ion binding | molecular_function |
| GO:0004518 | nuclease activity | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0016787 | hydrolase activity | molecular_function |
| GO:0003677 | DNA binding | molecular_function |
| GO:0003697 | single-stranded DNA binding | molecular_function |
| GO:0000287 | magnesium ion binding | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-050816-1 | Enables DNA binding activity and tyrosyl-DNA phosphodiesterase activity. Acts upstream of or within convergent extension involved in gastrulation; determination of left/right symmetry; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in nucleus. Predicted to be active in PML body and cytoplasm. Is expressed in Kupffer's vesicle; forerunner cell group; and tail bud. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 23. Orthologous to human TDP2 (tyrosyl-DNA phosphodiesterase 2). |
| ensembl_id | ENSDARG00000035954 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00029387 | True | 1727 | mRNA | 0.42 | 7 | 31568992 | 31576321 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_014892 | necab1 | coding | downstream | 46315 | 31437689 ~ 31522677 (-) |
| XLOC_014891 | tmem106bb | coding | downstream | 166563 | 31392350 ~ 31402429 (-) |
| XLOC_014890 | scin | coding | downstream | 196096 | 31347675 ~ 31372896 (-) |
| XLOC_014889 | arl4ab | coding | downstream | 227142 | 31339305 ~ 31341850 (-) |
| XLOC_014888 | BX465206.1 | coding | downstream | 485019 | 31079326 ~ 31083973 (-) |
| XLOC_014894 | C19H6orf62 | coding | upstream | 3070 | 31579391 ~ 31584444 (-) |
| XLOC_014895 | ripor2 | coding | upstream | 17132 | 31593453 ~ 31707892 (-) |
| XLOC_014896 | si:dkeyp-120h9.1 | coding | upstream | 166783 | 31743104 ~ 31765615 (-) |
| XLOC_014897 | hey1 | coding | upstream | 221246 | 31797567 ~ 31802296 (-) |
| XLOC_014898 | zbtb10 | coding | upstream | 302133 | 31878454 ~ 31900893 (-) |
| XLOC_014711 | CR382300.3 | misc | downstream | 11840237 | 19728690 ~ 19728755 (-) |
| XLOC_014885 | BX927219.1 | non-coding | downstream | 603331 | 30962723 ~ 30965661 (-) |
| XLOC_014883 | NA | non-coding | downstream | 733895 | 30831190 ~ 30835097 (-) |
| XLOC_014880 | NA | non-coding | downstream | 846488 | 30721012 ~ 30722504 (-) |
| XLOC_014879 | NA | non-coding | downstream | 945260 | 30592319 ~ 30623732 (-) |
| XLOC_014901 | CR382336.1 | non-coding | upstream | 754192 | 32330513 ~ 32330630 (-) |
| XLOC_014908 | CR318628.1 | non-coding | upstream | 1073346 | 32649667 ~ 32649781 (-) |
| XLOC_014919 | BX957357.1 | non-coding | upstream | 1796043 | 33372364 ~ 33372694 (-) |
| XLOC_014920 | NA | non-coding | upstream | 2206462 | 33782783 ~ 33786703 (-) |
| XLOC_014924 | CU928445.1 | non-coding | upstream | 2401557 | 33977878 ~ 33977994 (-) |
