XLOC_014941 (ak2)


Basic Information

Item Value
gene id XLOC_014941
gene name ak2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 35418683 ~ 35428914 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00029470
AACGGAGGCGTTACCACTTCCTTTCTAGGCTGAGAGAGTTAGTGGACGCAAAGTGTGTAGTGGAGAGAAGTGTGTTTAGTTAGTAAAGAAGCTGTAGCCATGGCCCCTAGCACACAAGAGGACGATACCGTCTCCGGTATACGGAAAGGCATACGGGCCATTCTGCTCGGGCCGCCCGGCGCGGGGAAGGGAACGCAGGCACCCAAGCTTGCAGAGAAATACTGCGTGTGCCATTTAGCTACTGGGGACATGCTGAGGGCTATGGTGGCATCTGGCTCAGAGCTCGGCCAGCGTCTAAAGGAAACCATGGATGCCGGCAAACTGGTGAGTGATGAGATGGTGGTGGAGCTCATAGACAACAACCTGGACACACCAGCATGCAAGAATGGATTCCTGCTGGACGGATTTCCCCGCACCGTCAAACAAGCAGAAATGCTGGATGACCTCATGGAGAAGCGTAGTGAGAAACTGGACTCTGTTATTGAGTTCTCTGTCGATGACTCCCTGCTAGTCCGCAGGATCTGTGGAAGGCTCATTCATCAGCCCAGCGGGCGATCTTATCATGAAGAGTTTCATCCTCCCAAGGAGCACATGAAGGATGATGTGACCGGAGAACCTCTGATCCGCCGTAGTGATGATAATGAAACTACTCTGCGCTCTCGACTAGAGTCTTACCACAGGCAGACGTCTCCTCTAGTGCAGTACTACAGCGCCCGCGGCCTGCACACCGCCATCGATGCTTCTCAGTCCACCGACCTCGTCTTTGCCTCAATCCTCGCTGCCTTCTCTGCTGCTACCTGTAAAGATCTCGTTTATTTTGTCTAAATAATCTCTGCATCTCCTCTTCCTTGTATgctttataatcattaaattcATTTCGTGCTTTGTGGCAAAACATGGCTCTTCTgaggaaaaaaatcaataataaatttgATTGTAAAACTCAAACTAAATGTAATGTCTCATTGATTAGGATTACATTCAGTTGTTTATAAGCCTTCATTTTACGATGGTACTGTAGCGCTTTTTCTCTAACCAGACACCTGTAAAAAGGTATGGTTATGTCATTTACactaaatgaaatgtaataattaCTAAGACTTTCTGGTTGTCTTGAGTCTTGTAGTAATGCACGATCTCCACCAGAGGTCGTATGAATGCCTGGTTACATTATTGAATGAAAGAAATTAATCATTAAATGCTTTATTGCTTATGTTTATCAGTCTGTGAATCATTAATTTACGTCTGgaactttctcttttttttcctgcagCTGTATGAAATCCAGTTTCTCCCATCCAGGTTGAACCAGATGTGAAAATAATGGATGGGGGGGGGAAAGGGGACGCTGGAAGTGTCTCAGATGTTAATTTTTGAACATTCCATGTAGTGAGTGTGTTTTGTAATGAACACCGATTCGACTGAAACCCAGTTGATGACCTCCAATAAACTGGAGAATATTTTCTACTACATTACAA
>TCONS_00029471
ATGGCCCCTAGCACACAAGAGGACGATACCGTCTCCGGTATACGGAAAGGCATACGGGCCATTCTGCTCGGGCCGCCCGGCGCGGGGAAGGGAACGCAGGCACCCAAGCTTGCAGAGAAATACTGCGTGTGCCATTTAGCTACTGGGGACATGCTGAGGGCTATGGTGGCATCTGGCTCAGAGCTCGGCCAGCGTCTAAAGGAAACCATGGATGCCGGCAAACTGGTGAGTGATGAGATGGTGGTGGAGCTCATAGACAACAACCTGGACACACCAGCATGCAAGAATGGATTCCTGCTGGACGGATTTCCCCGCACCGTCAAACAAGCAGAAATGCTGGATGACCTCATGGAGAAGCGTAGTGAGAAACTGGACTCTGTTATTGAGTTCTCTGTCGATGACTCCCTGCTAGTCCGCAGGATCTGTGGAAGGCTCATTCATCAGCCCAGCGGGCGATCTTATCATGAAGAGTTTCATCCTCCCAAGGAGCACATGAAGGATGATGTGACCGGAGAACCTCTGATCCGCCGTAGTGATGATAATGAAACTACTCTGCGCTCTCGACTAGAGTCTTACCACAGGCAGACGTCTCCTCTAGTGCAGTACTACAGCGCCCGCGGCCTGCACACCGCCATCGATGCTTCTCAGTCCACCGACCTCGTCTTTGCCTCAATCCTCGCTGCCTTCTCTGCTGCTACCTCTGTATGAAATCCAGTTTCTCCCATCCAGGTTGAACCAGATGTGAAAATAATGGATGGGGGGGGGAAAGGGGACGCTGGAAGTGTCTCAGATGTTAATTTTTGAACATTCCATGTAGTGAGTGTGTTTTGTAATGAACACCGATTCGACTGAAACC
>TCONS_00029473
CTTTCTAGGCTGAGAGAGTTAGTGGACGCAAAGTGTGTAGTGGAGAGAAGTGTGTTTAGTTAGTAAAGAAGCTGTAGCCATGGCCCCTAGCACACAAGAGGACGATACCGTCTCCGGTATACGGAAAGGCATACGGGCCATTCTGCTCGGGCCGCCCGGCGCGGGGAAGGGAACGCAGGCACCCAAGCTTGCAGAGAAATACTGCGTGTGCCATTTAGCTACTGGGGACATGCTGAGGGCTATGGTGGCATCTGGCTCAGAGCTCGGCCAGCGTCTAAAGGAAACCATGGATGCCGGCAAACTGGTGAAATGAATGTTTCCatatttacattacttttagTCCAATATGCTACTTGGATGGAATAAATGCTGAGTCTCTCTTCATCTCTCATTTTCTTTAGGTGAGTGATGAGATGGTGGTGGAGCTCATAGACAACAACCTGGACACACCAGCATGCAAGAATGGATTCCTGCTGGACGGATTTCCCCGCACCGTCAAACAAGCAGAAATGCTGGATGACCTCATGGAGAAGCGTAGTGAGAAACTGGACTCTGTTATTGAGTTCTCTGTCGATGACTCCCTGCTAGTCCGCAGGATCTGTGGAAGGCTCATTCATCAGCCCAGCGGGCGATCTTATCATGAAGAGTTTCATCCTCCCAAGGAGCACATGAAGGATGAT

Function

symbol description
ak2 Predicted to enable adenylate kinase activity. Acts upstream of or within hematopoietic stem cell differentiation and leukocyte differentiation. Predicted to be located in mitochondrial intermembrane space. Predicted to be active in mitochondrion. Is expressed in head; hematopoietic system; intermediate cell mass of mesoderm; and otic vesicle. Used to study reticular dysgenesis. Human ortholog(s) of this gene implicated in reticular dysgenesis. Orthologous to human AK2 (adenylate kinase 2).

GO:

id name namespace
GO:0002244 hematopoietic progenitor cell differentiation biological_process
GO:0002521 leukocyte differentiation biological_process
GO:0046033 AMP metabolic process biological_process
GO:0046034 ATP metabolic process biological_process
GO:0006139 nucleobase-containing compound metabolic process biological_process
GO:0006163 purine nucleotide metabolic process biological_process
GO:0006172 ADP biosynthetic process biological_process
GO:0009132 nucleoside diphosphate metabolic process biological_process
GO:0060218 hematopoietic stem cell differentiation biological_process
GO:0016310 phosphorylation biological_process
GO:0005758 mitochondrial intermembrane space cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0016776 phosphotransferase activity, phosphate group as acceptor molecular_function
GO:0004017 adenylate kinase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016301 kinase activity molecular_function
GO:0019205 nucleobase-containing compound kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-512 Predicted to enable adenylate kinase activity. Acts upstream of or within hematopoietic stem cell differentiation and leukocyte differentiation. Predicted to be located in mitochondrial intermembrane space. Predicted to be active in mitochondrion. Is expressed in head; hematopoietic system; intermediate cell mass of mesoderm; and otic vesicle. Used to study reticular dysgenesis. Human ortholog(s) of this gene implicated in reticular dysgenesis. Orthologous to human AK2 (adenylate kinase 2).

Ensembl:

ensembl_id ENSDARG00000005926

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00029470 False 1478 mRNA 0.45 6 35418683 35428914
TCONS_00029471 False 856 mRNA 0.53 7 35418732 35428815
TCONS_00029473 True 680 processed_transcript 0.50 4 35421677 35428894

Neighbor

gene id symbol gene type direction distance location
XLOC_014940 rnf19b coding downstream 17864 35379899 ~ 35400819 (-)
XLOC_014939 ndufs5 coding downstream 57127 35357196 ~ 35361556 (-)
XLOC_014938 macf1a coding downstream 78656 35039902 ~ 35340027 (-)
XLOC_014937 bmp8a coding downstream 382826 35019304 ~ 35035857 (-)
XLOC_014936 si:rp71-45k5.4 coding downstream 408341 35001253 ~ 35010342 (-)
XLOC_014943 anln coding upstream 4241 35433155 ~ 35450857 (-)
XLOC_014944 ptp4a2b coding upstream 26258 35455172 ~ 35492784 (-)
XLOC_014945 col8a2 coding upstream 67368 35496282 ~ 35596207 (-)
XLOC_014946 trappc3 coding upstream 293988 35722902 ~ 35733401 (-)
XLOC_014947 csmd2 coding upstream 685932 36114846 ~ 36675023 (-)
XLOC_014711 CR382300.3 misc downstream 15689928 19728690 ~ 19728755 (-)
XLOC_014929 NA non-coding downstream 731131 34660712 ~ 34687552 (-)
XLOC_014928 NA non-coding downstream 1135675 34281886 ~ 34283008 (-)
XLOC_014927 NA non-coding downstream 1188398 34188192 ~ 34230285 (-)
XLOC_014924 CU928445.1 non-coding downstream 1440689 33977878 ~ 33977994 (-)
XLOC_014920 NA non-coding downstream 1631980 33782783 ~ 33786703 (-)
XLOC_014948 NA non-coding upstream 1281584 36710498 ~ 36731093 (-)
XLOC_014949 NA non-coding upstream 1400037 36828951 ~ 37120328 (-)
XLOC_014951 BX571837.1 non-coding upstream 1798996 37227910 ~ 37228025 (-)
XLOC_014953 NA non-coding upstream 2093663 37522577 ~ 37569033 (-)
XLOC_014954 NA non-coding upstream 2140710 37569624 ~ 37571866 (-)

Expression


Co-expression Network