XLOC_015041 (krit1)


Basic Information

Item Value
gene id XLOC_015041
gene name krit1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 45991054 ~ 46018152 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00029622
tttttttattcgtttatttttttgtttattgtatatttatttttatttactttttattatttaagtttattttttattttgtttttatatttgtttttgttattgtatacttttttatgtaattttattttattaatattttattatttattttgtttgtttttttttcttttttttcatttcttttttaaatttgtttttgttgttctttttcttttttttaattcgcccatagatatatacatatctaTGGAATTGGCCGACTTCTCCAGGAGTTTATCGGAGACCTTTATTTTGAAGTTCTGCTCATTTCCTTTAGCAGCCGGAAGAGTGTCTTTGTTGTTAGAAATATGACAGAAGAATAGAGGCATGGTGCTTAAAGAGTTAATGACAGCTGGATCTAAAGAGGAGCTGCATGATGGGAAACCAAGAGCTAGAGGAGGTGTTTGTTGCTGTTATCCGACCAAAAAACACAACCAGCCTCAACTCCAAAGAATACCGTGCTAAATCCTATGAGATTTTACTTATCGAAGTTCCCCTGGAGGGAAAAGAGAAAAAGCGGAAGAAAGTGCTGCTTGGGACTAAAATCCACGCCGACAGTGACCGGACAAAGTCAATTCTGGAGTTTGTGGATGAAACCACCAAGCCCATATCCAATAACCAGGGCATAATAGGGAAGCGTGTCGTGCACATGAGGAAGTTCCTGTTAGATGGAGACAGTGGAGGAAAAGAGGCCTCGTTATTTATTGTGCCAATTAATGTCAAAGACAACAGCAAGTCCGTGCATCACCCTGGGAGCCCCAGTTTCTACTGCCTTCAGGACATCATGCGTGTGTGTAGTGAAACCAGTGCTCATTTCTCCTCCAGCACCTCAAAGATGCTGCTCGCTCTCGACAAGTGGTTAGCGGAGCAGCACACTGTGCCTCACGCTATTCCTGCTCTGTTCCGGCCGGCTCCGGTGGACCGTGTGAAAACTAACGTGAGTAACCCGGCGTACGCAGTGGAGAAGCAGACAGACGGGACGCTGCACATGGGCTACACGGCTCTGGAGATCAAGAGTAAACTGATGTCTCTGGAGAAAGCAGATCTGTGCATCCAGAACCCGCTGTACGGCTCAGATCTGCAGTACACCAACAGAGTGGACAAAGTCATCATCAACCCTTACTTTGGCTTGGGAGCTCCAGATTACTCCAAAATCCAGATTCCAAAGAGAGACAAATGGCAGCACAGCATGACCAGCGTCACCGAAGACAAAGAGCGCCAGTGGGTGGATGATTTCCCTCTGCACCGAAGCGCCTGTGAGGGAGACACTGAGCTTTTGTCTAAATTGCTGGATGGCGGATTCTCAGTCAAACAGCTGGACAGCGACCATTGGGCACCCATTCATTATGCATGCTGGCATGGGAAGGTGGAGGCCACTAAACTGCTGCTGGAGAAAGGCAACTGTAACCCCAACCTGCTGAACGGCCAGCTGAGCTCTCCTTTACACTTCGCAGCTATCGGCGGTCATGCAGAAATCGTGCAGCTCCTCCTGCAGCACCCAGAGATCGACAGACACATCGAGGACCAGCAGAAACGATCGCCGCTTCAAGTATGTGAAGAAAACAAGCAGAACAACTGGGAGGAAACCGTGAATCTCCTTCAACAAGCCAGCAATAAACCATACGAGAAGGTGAGGATTTACCGTATGGATGGATCGTACCGCTCTGTGGAGCTGAAGCATGGGAACAACACCACCGTGCAGCAGATCATGGAGGGCATGAGATTATCACAGGAGACCCAGCAGTATTTTACCATCTGGATCTGCTCCGAAAACCTTAGTCTGCAGCTGAAGCCGTACCACAAGCCCTTGCAGCACTTACGGATGTGGAGCGAGATCGTGACGGATCTCACTGCTCTGGATCCACAGAGAGAAAGTCCACAGCTCTTCCTGCGCAGAGACGTTCGGCTGCCTTTAGAGGTCGAGAAAAAGGTTGAAGATCCGCTGTCCATCCTCATCCTATTTGATGAAGCTCGTCACTGCCTCCTTAAAGGTTTCCTCTCGACGTCAGATAACAAGCTAATCACGCTCGCAAGCCTCCTCCTGCAGATCATCTACGGAAACTACGACAGCAAGAAGCACAAACAGGGCTTTCTAAATGAGGAAAACCTGAAATCCATAGTTCCCATTTCAAAGGTCAAGAGCAAAGCACATCACTGGACTAACAGGATACTTCACGAGTACAAGAGTCTGAGCACTAGTGAGGGTGTGAGTAAAGAAATGCATCACCTCCAGAGGCTCTTCCTGCAGAACTGCTGGGATATTCCTACTTATGGTGCAGCGTTTTTCACAGGACAGGTCTTCACTAAAGCCAGCTCCAGCACACACAAGGTGATCCGCGTGTATGTGGGCGTCAACACCAAAGGCCTGCATCTGATGAACATGGAGACAAAAGTGCTTCACCTCAGTCTGGAGTATGGGACATTTATGTGGCAGCTGGGTCAGGCTGATCAATACGTGCAAATCCACAGTCTGGAGAACAAGAAGAACTTTGTCGTTCACACCAAACAGGCTGGTCTTATCGTGAAGCTGCTGATGAAGCTGAGTGGACAAATTGCACCAAACGACAGAGCTGTGTCTGATAAATATGCGTATGGGTAACCAAATCACACACAAGCttgttcattttagttttagtttttattcttatGCTGTCAGAAAACTAAATGTTGTTTATACCAAAAGGAGACAGTTATAcatattataaatgtgtttaccATGTAATATTTTCTTACTgatattatttgcattttataatGTCATGATAGACTTGTGCTTTTAACCGTTGTTGTAAATATGAacagtcattttaataaaaaaaatgcacaaaaagtgAACAAA
>TCONS_00029623
GTCTGCAGCTGAAGCCGTACCACAAGCCCTTGCAGCACTTACGGATGTGGAGCGAGATCGTGACGGATCTCACTGCTCTGGATCCACAGAGAGAAAGTCCACAGCTCTTCCTGCGCAGAGACGTTCGGCTGCCTTTAGAGGTCGAGAAAAAGGTTGAAGATCCGCTGTCCATCCTCATCCTATTTGATGAAGCTCGTCACTGCCTCCTTAAAGGTTTCCTCTCGACGTCAGATAACAAGCTAATCACGCTCGCAAGCCTCCTCCTGCAGATCATCTACGGAAACTACGACAGCAAGAAGCACAAACAGGGCTTTCTAAATGAGGAAAACCTGAAATCCATAGTTCCCATTTCAAAGGTCAAGAGCAAAGCACATCACTGGACTAACAGGATACTTCACGAGTACAAGAGTCTGAGCACTAGTGAGGGTGTGAGTAAAGAAATGCATCACCTCCAGAGGCTCTTCCTGCAGAACTGCTGGGATATTCCTACTTATGGTGCAGCGTTTTTCACAGGACAGGTCTTCACTAAAGCCAGCTCCAGCACACACAAGGTGATCCGCGTGTATGTGGGCGTCAACACCAAAGGCCTGCATCTGATGAACATGGAGACAAAAGTGAGACTTCAACCACTCATGGATGCTTTCACAAAACGGGAAAAATCTAGAGGAGCATAGCAAAAATACAGTGTAGTTGAAATTATGTAGTTTGACATTTTTTGCAATAACTTTACTTGAGTGAccaaactgttttatttaaatgaaccaaCATTTTTCcctctatattcactgagaaattgattaaaaa

Function

symbol description
krit1 Acts upstream of or within several processes, including circulatory system development; endothelial cell morphogenesis; and negative regulation of endothelial cell differentiation. Predicted to be located in several cellular components, including cell junction; cytoplasm; and cytoskeleton. Predicted to be active in plasma membrane. Is expressed in head; notochord; post-vent region; posterior cardinal vein; and ventricular zone. Used to study cerebral cavernous malformation 1. Human ortholog(s) of this gene implicated in cerebral cavernous malformation and cerebral cavernous malformation 1. Orthologous to human KRIT1 (KRIT1 ankyrin repeat containing).

GO:

id name namespace
GO:0007507 heart development biological_process
GO:0048514 blood vessel morphogenesis biological_process
GO:0007275 multicellular organism development biological_process
GO:0003181 atrioventricular valve morphogenesis biological_process
GO:0001525 angiogenesis biological_process
GO:0007033 vacuole organization biological_process
GO:0001568 blood vessel development biological_process
GO:0009948 anterior/posterior axis specification biological_process
GO:0045602 negative regulation of endothelial cell differentiation biological_process
GO:0001570 vasculogenesis biological_process
GO:0001886 endothelial cell morphogenesis biological_process
GO:0003007 heart morphogenesis biological_process
GO:0072554 blood vessel lumenization biological_process
GO:0060047 heart contraction biological_process
GO:0005856 cytoskeleton cellular_component
GO:0005886 plasma membrane cellular_component
GO:0030054 cell junction cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component

KEGG:

id description
ko04015 Rap1 signaling pathway
ko04212 Longevity regulating pathway - worm

ZFIN:

id description
ZDB-GENE-030131-555 Acts upstream of or within several processes, including circulatory system development; endothelial cell morphogenesis; and negative regulation of endothelial cell differentiation. Predicted to be located in several cellular components, including cell junction; cytoplasm; and cytoskeleton. Predicted to be active in plasma membrane. Is expressed in head; notochord; post-vent region; posterior cardinal vein; and ventricular zone. Used to study cerebral cavernous malformation 1. Human ortholog(s) of this gene implicated in cerebral cavernous malformation and cerebral cavernous malformation 1. Orthologous to human KRIT1 (KRIT1 ankyrin repeat containing).

Ensembl:

ensembl_id ENSDARG00000098916

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00029622 False 2881 mRNA 0.44 17 45991054 46018152
TCONS_00029623 True 804 lncRNA 0.45 4 45993896 45999223

Neighbor

gene id symbol gene type direction distance location
XLOC_015040 si:ch211-153f2.3 coding downstream 5065 45983647 ~ 45985989 (-)
XLOC_015039 eif3hb coding downstream 30863 45856171 ~ 45960191 (-)
XLOC_015038 NA coding downstream 300639 45689237 ~ 45690415 (-)
XLOC_015037 trps1 coding downstream 340060 45375669 ~ 45650994 (-)
XLOC_015036 FP340497.1 coding downstream 746346 45157502 ~ 45244708 (-)
XLOC_015042 nup153 coding upstream 1161 46019313 ~ 46058963 (-)
XLOC_015043 ptdss1b coding upstream 48737 46066889 ~ 46091605 (-)
XLOC_015044 si:ch1073-228h2.2 coding upstream 199947 46218099 ~ 46219035 (-)
XLOC_015045 NA coding upstream 394461 46412613 ~ 46420558 (-)
XLOC_015046 ext1b coding upstream 403197 46421349 ~ 46566430 (-)
XLOC_014711 CR382300.3 misc downstream 26262299 19728690 ~ 19728755 (-)
XLOC_015035 NA non-coding downstream 983997 45003801 ~ 45007057 (-)
XLOC_015031 NA non-coding downstream 2090002 43897940 ~ 43901052 (-)
XLOC_015028 NA non-coding downstream 2279761 43704915 ~ 43711293 (-)
XLOC_015047 NA non-coding upstream 473431 46491583 ~ 46492033 (-)
XLOC_015051 NA non-coding upstream 981109 46999261 ~ 47173408 (-)
XLOC_015054 CU929178.2 non-coding upstream 1382037 47400189 ~ 47400307 (-)
XLOC_015055 CU929178.1 non-coding upstream 1397438 47415590 ~ 47416405 (-)

Expression


Co-expression Network