XLOC_015046 (ext1b)


Basic Information

Item Value
gene id XLOC_015046
gene name ext1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 46421349 ~ 46566430 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00029634
CATTAACGACTTTCCATCGGGACTCTCCGCCAGATGAACTCCATGAGTCCCGACGCGTTCATCTAACGTTAGCGAGTGTCCTGTCAACAAACCGGCTAGTTCGACCACTCCAACTAACAACCGTTAAAAACCCGGCTCGACCACCCACAACTACGAgattgtgtgtgcgcgcgtttgtGATGATCCTAACAGGGACGGTTACCGCTGAAATGGTGCTACCCGACAGACGAGGGAGATCGGTGTAAAATCGCCCACATGTACTGGATCAATCGCTTGCTGGTAGCTGATCGGAATCCGAAGCGGGAAGAAGAAGACGTGAGTTGTAAATCCTCGCAGGCTGGAAGATGGCGGAGCAGCACCATAGCTGGAGGAGGTGGTGGTGTTGAGGGACAAACTTCCAAACGCTTGAGATTTATTTCCAAACAGCGCGATCTGGCCTTCAGGACACATGCAGGCCAAAAAACGATATCTGATCTCGCTCTTGACTGGCGCCTTTCTAGTTCTGCTCATTTACTTGGGAGGAGGAGGGGTCCCGGGTCCCGCGGCCCCGGGCTCCAGGAGCCGGACACATGGATACAACCGGCCCGATCAGCCGTGGCCACACTTCTCGGACCCCTTACTACACTTCAGCCCGTGGGACCACTCGGACACGGAGGACTATAACGTGCACATATCGCCCAGGCAGAAGAGAGATGTGAACTCCAGCGTGTATAAGGGTAAGCGGTGCCGCATGCAATCCTGCTTTGAtttctcgctctgccaacggaaCGGCTTCAAAGTCTACGTGTATCCGCAGCAGAAGGGGGAGAAGATATCGGAAAGTTACCAGAACATCTTATCCACCATCGAGGGCTCTAGATTTTACACCTCTGACCCTGGtcaggcgtgcgtgtttgtgcTGAGCTTGGACACTCTCGACCGAGACCAGTTGTCTCCGCAGTATGTGCACAATCTCAAAACTAAAGTGCAGAGCTTGGCTCTGTGGAACAACGGTAGGAATCACctcatatttaatttgtattctgGCACATGGCCTGATTACACGGAAGATTTGGGCTTTGACATTGGTCAGGCCATGCTGGCCAAAGCTAGCATCAGCACCGAGAACTTCAGACCCAACTTTGACATCTCCATCCCCTTGTTCTCCAAGGAGCACCCGAGGACCGGCGGGGACAGGGGCTACTTGAAATACAACACCATTCCACCTTTTAGAAAGTATATGTTGGTATTTAAGGGCAAGCGCTATTTGACAGGCATCGGCTCGGACACGAGGAATGCTTTATATCACGTTCATAACGCGGAGGATGTAGTGCTGCTCACCACCTGCAAACATGGCAAAGACTGGCAGAAACACAAGGACGCGCGCTGTGACAAGGACAACGCAGAGTATGACAAgtacgACTACCGTGAAATGCTGCACAACTCTACCTTCTGTCTGGTTCCTCGAGGACGACGCCTGGGATCCTTCCGCTTCCTGGAGGCTCTTCAGgcggCCTGTGTGCCGGTGATGCTGAGTAACGGTTGGGAGCTCCCCTTCTCGGAGGTCATCGACTGGAACACTGCTGCTGTGATCGGGGACGAGAGGCTCCTGCTGCAGATCCCGTCCACTGTTCGCTCCATCCATCAGGACAAGATCCTGGCTCTCCGACAGCAGACGCAGTTCCTCTGGGAGGCCTATTTCTCTTCAGTGGAGAAGATCGTGCTCACCACTCTAGAAatCATCCAGGACCGGGTGCTCCAGCAGAGCTCCAGAAGCAGTGTGATGTGGAACAGTCACCCCGGTGGACTCTTCTCTCTGCCGCAGTACTCCTCATATCTGGGAGACTTTCCTTTCTTCTACGCCAAACTCGGCATCAAGCCGAGTCCCAAGTTCACTGCAGTTATCCATGCAGTGACGCCGCTGGTTTCTCAATCTCAGCCCATTCTCAAGCTCATCGTCTCAGTGGCCAGATCACAGTACTGCGCTCAGattaTTGTGTTGTGGAACTGTGACAAGCCTTTACCTGCCAAACAGCGCTGGCCGGCCACTGCAGTGCCCATTATAGTGATTGAAGGAGAAAACaaggtgATGAGCAGCCGTTTTCAGCCGTATGAAAGCCTCATCAGTGATGCGGTGTTGAGTCTGGATGAAGACACTGTGTTGTCCACCACTGAGGTGGACTTTGCCTTCACGGTGTGGCAGAGTTTCCCGGAGAGGATTGTGGGATATCCTGCCCGCAGTCATTTCTGGGACAATAATAAGGAGCGCTGGGGTTACACTTCCAAATGGACCAACGACTATTCAATGGTTCTCACCGGAGCTGCCATTTACCACAGATATTACCACTTCCTGTACACCCACTTCCTGCCAAGCAGCCTGAAGAGTATGGTGGACCAGCTGGCCAACTGTGAGGATATCCTGATGAACTTCCTGGTGTCTGCGGTCACTAAACTGCCACCGGTCAAAGTCACGCAGAAGAAGCAGTACAAGGAGACCATGATGGGtcagTCGTCTCGAGCCTCGCGCTGGGCCGATCCGGACCACTTCGCCCAGCGGCAGACCTGCATGAACAAGTTCGCCAGCTGGTTTGGCGGCATGCCCCTGGTGCACTCCCAAATGAGACTGGACCCCGTTCTGTTCAAGGACCAGGTCTCCATCCTGCGCAAGAAATACAGGGAGATCGAGCGGCTCTGACCAGACTGGCGCCCCCTGCTGGACGTTCAACAGGGGGCCGTAAGAGACTCTGAAAGGAGAACTGGAGCCCGAGAGCTTTCCTTCAGCACATAcgcgaaacacacacacatctgacggACACCTCTGGAGGGAAGATTTGGTTTTGGGGACGCCACAGATGATCTTTCCCAGCACACGAGCGACAGGAGGGACGCATCATTGTGTTTAGCACTTCATATCCATCCACATCCATTCATACGCGTGTTATCAAAAGTGCCCACTGTGAACCAAGCAaaactcttaaagggacagttcaccc

Function

symbol description
ext1b Predicted to enable N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity and glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to act upstream of or within protein glycosylation. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including axial mesoderm; brain; germ ring; pronephric duct; and tail bud. Human ortholog(s) of this gene implicated in chondrosarcoma; hereditary multiple exostoses; and trichorhinophalangeal syndrome type II. Orthologous to human EXT1 (exostosin glycosyltransferase 1).

GO:

id name namespace
GO:0015012 heparan sulfate proteoglycan biosynthetic process biological_process
GO:0006486 protein glycosylation biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0030176 integral component of endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016740 transferase activity molecular_function
GO:0016757 transferase activity, transferring glycosyl groups molecular_function
GO:0046872 metal ion binding molecular_function
GO:0015020 glucuronosyltransferase activity molecular_function
GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity molecular_function
GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity molecular_function
GO:0008375 acetylglucosaminyltransferase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050211-4 Predicted to enable N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity and glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to act upstream of or within protein glycosylation. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including axial mesoderm; brain; germ ring; pronephric duct; and tail bud. Human ortholog(s) of this gene implicated in chondrosarcoma; hereditary multiple exostoses; and trichorhinophalangeal syndrome type II. Orthologous to human EXT1 (exostosin glycosyltransferase 1).

Ensembl:

ensembl_id ENSDARG00000101019

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00029634 True 2972 mRNA 0.53 11 46421349 46566430

Neighbor

gene id symbol gene type direction distance location
XLOC_015045 NA coding downstream 791 46412613 ~ 46420558 (-)
XLOC_015044 si:ch1073-228h2.2 coding downstream 202314 46218099 ~ 46219035 (-)
XLOC_015043 ptdss1b coding downstream 329744 46066889 ~ 46091605 (-)
XLOC_015042 nup153 coding downstream 362386 46019313 ~ 46058963 (-)
XLOC_015041 krit1 coding downstream 403197 45991054 ~ 46018152 (-)
XLOC_015048 SAMD12 coding upstream 157781 46724211 ~ 46764361 (-)
XLOC_015049 abrab coding upstream 201836 46768266 ~ 46777963 (-)
XLOC_015050 angpt1 coding upstream 245842 46812272 ~ 46957968 (-)
XLOC_015051 NA coding upstream 432831 46999261 ~ 47173408 (-)
XLOC_015052 sdc2 coding upstream 624575 47191005 ~ 47276297 (-)
XLOC_014711 CR382300.3 misc downstream 26692594 19728690 ~ 19728755 (-)
XLOC_015038 NA non-coding downstream 730934 45689237 ~ 45690415 (-)
XLOC_015036 FP340497.1 non-coding downstream 1176641 45157502 ~ 45244708 (-)
XLOC_015035 NA non-coding downstream 1414292 45003801 ~ 45007057 (-)
XLOC_015031 NA non-coding downstream 2520297 43897940 ~ 43901052 (-)
XLOC_015054 CU929178.2 non-coding upstream 833759 47400189 ~ 47400307 (-)
XLOC_015055 CU929178.1 non-coding upstream 849160 47415590 ~ 47416405 (-)
XLOC_015061 CU695215.1 non-coding upstream 1001283 47567713 ~ 47567848 (-)
XLOC_015063 NA non-coding upstream 1194467 47760897 ~ 47761491 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000096_00447205_00452255 NA coding CI01000096 null 445702 ~ 453382 (-)