XLOC_015067 (ctnnb2)


Basic Information

Item Value
gene id XLOC_015067
gene name ctnnb2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 47975916 ~ 47997424 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00029665
AGGGAGAGCGGAGAGAACTGACGCACCGTGACCGGAGAGAATAACGAGAAACACCGGTGGATTCACTGCTTACAAGACACCAACGAGAAGGTCAGGCTCCACGGCCGCTGCACGGAGCTCTCCGGTTCAGGTTTGAAAGTCGCTCAGGCTAAAGGATTGACGCAACGATGGCTAGCCAGGctGACCTGATGGAGCTGGACATGGCCATGGAGCAGGACCGTAAGGCTGCAGTGAGCCACTGGCAGCAGCAGTCCTACCTGGATTCAGGGATTCACTCGGGCGCCACCACCACTGCGCCCTCGCTCTCAGGCAAAGGAAACCCAGAGGAAGAGGATCTGGACAACCAGGTGCTGTACGAGTGGGAGCAGGGCTTCAGCCAGCCCTTCACACCTGAGCAGGTGGCAGATCTGGACGGGCAGTATGCCATGACGCGGGCGCAGAGGGTTCGAGCCGCCATGTTCCCAGAGACTCTGGATGAGAGCGTCCCGATGGCCTCCACCCAGTTCGACTCTGCTCATCCAACAAACGTACAGCGTCTGGCGGAGCCGTCGCAGATGCTGAAGCATGCGGTGGTCAACCTCATCAACTACCAGGACGATGCAGAGCTCGCCACCAGAGCCATTCCAGAGCTCACCAAACTGCTGAACGACGAGGACCAGGTGGTGGTGAATAAAGCCGCAGTGATGGTGCACCAGCTCTCCAAGAAGGAGGCGTCCCGCCATGCCATCATGCGCTCTCCACAGATGGTGTCGGCCATCGTGAGGACCATGCAGAACACCAACGATGTGGAGACGGCCCGCTGCACCGCCGGCACACTGCACAACCTGTCCCACCACAGAGAGGGGCTGCTGGCCATCTTCAAGAGCGGAGGGATCCCGGCCCTCGTCAAGATGCTCGGGTCTCCTGTGGACAGTGTGCTGTTTTACGCCATCACCACCCTCCACAACCTCCTGCTGCATCAGGAAGGGGCCAAGATGGCTGTGCGTCTGGCTGGAGGTCTGCAGAAGATGGTGGCGCTGCTCAACAAAACCAACGTCAAGTTCCTCGCCATCACCACAGACTGCCTGCAGATCCTGGCCTACGGCAACCAGGAGAGCAAGCTGATCATCCTGGCCAGTGGAGGACCGCAGGCTCTTGTCAACATCATGAGGACTTACAACTATGAGAAGCTGCTGTGGACCACCAGTCGTGTGCTGAAAGTGCTGTCCGTCTGCTCCAGCAACAAACCTGCCATCGTGGAGGCTGGTGGTATGCAGGCTCTTGGCCTTCACCTGACAGACCCCAGTCAGCGTCTGGTTCAGAACTGCCTCTGGACCCTCAGAAACCTGTCAGATGCTGCCACAAAGCAGGAGGGCATGGAGGGTCTGCTGGGGACGCTGGTGCAGCTGCTGGCGTCTGATGACATTAACGTGGTGACCTGCGCCGCCGGCATCCTCTCCAACCTCACCTGCAACAACTACAAGAACAAGATGATGGTGTGTCAGGTGGGTGGCATCGAGTCGCTGGTGCGGACCGTGCTCAGAGCGGGAGACCGAGAGGACATCACGGAGCCGGCGGTGTGCGCGCTGCGACACCTCACCTCCAGACACCAGGACGCAGAGATGGCCCAGAATGCAGTGCGGCTCCACTATGGCCTGCCAGTGGTGGTCAAGCTGCTCCACCCGCCCTCACACTGGCCGCTCATTAAGGCCACTGTGGGTCTGATCCGGAACCTGGCTCTGTGTCCGGCCAATCACGCGCCGCTCCGCGAGCAGGGCGCCATCCCTCGCCTGGTGCAGCTGCTGGTGCGGGCGCATCAGGACACACAGAGGCGCACCTCCATGGGCGGCACACAGCAGCAGTTCGTGGAGGGCGTGCGCATGGAGGAGATCGTAGAGGGCTGCACCGGTGCTCTTCATATCCTGGCCAGAGACGTTCACAACCGCATCGTCATCAGAGGACTCAACACCATCCCTCTGTTCGTACAGctgctGTATTCCCCCATCGAGAACATCCAGCGTGTAGCAGCGGGCGTCCTCTGTGAGCTGGCGCAGGATAAGGAGGCGGCGGAGGCCATCGAGGCTGAAGGAGCCACAGCTCCACTCACTGAACTGCTGCACTCCAGGAACGAGGGCGTGGCCACATACGCCGCAGCCGTGCTCTTCCGCATGTCTGAGGACAAACCACAGGACTATAAGAAGCGTCTGTCAGTGGAGCTCACCAGCTCACTCTTCAGAACCGAGCCCATGGCCTGGAATGAGACTGCTGATCTAGGTCTGGATATCGGTGCTCCAGGAGAGACACTCGCATACAGAGCAGACGAGCCCAGTTACCGCTCCTTCCACTCGGGCTATGCTGCAGAGGCTCTGGGCATGGAGGGTCTGCTGGAGCAGGAGATGTCGCATCACCCCGGGGCAGAGTTCCCTGTGGAGGCGCTGCCGGATCTGGCCCACGCTCAGGATCTGATGGACGGCCTGCCCAACACTGACTCCAATCAGCTGGCCTGGTTCGACACGGACCTGTAGAGAGCTGCTGAGCGaaggacagCTGAATGAAGAGAGAATCTGTATGGTGAAGGAAGGTTTGAGGATGAGCTGGAGGTTCAGAAAGTGCCTGATGagtgcgtacacacacacacacacacacacacacacacacaggaggacAGCTGGACGGACGGCTGTAGTGTAGTCCAGATGGAGCAGTGGGACGCGGTTGCGGACGAACACACGGACTCTCGGTCTGAAGACGGAACTCTTTTACTCTTTATTTTCATCCTCTTCGGttattcctcctcctcctcctcctcatggTACTGACCCGAGCTTTGTTTTTATCCTGCTCTTTTCTTTGTTTGTGTAGTGTTTAGTAGCGTCTCTCCTCATGGGTCGGTCACTGATGTACAACACTAATCTGAGTTCTGTCTGATCGGGCCGAACGCAGAATATCGAGTAGCTTTTCTATGCGGGGTTAAACGGTGGTTATTGAGTACAGAACCTATATTATATGCATTGTGGAGGTGTTCTGGGTGTGTTCTGGGTGAGTGGGGGGGGTAGATTACtgggtcaaacacacacacacacacacacacacacacagatcttttCTATGATGATATGAGGAGCGATGGCGCTTCTTCTGGGAACACGGAGGAGGACGAGGCTGATCAATAAGAGACTTTATTCCATTTGTCCACTGGTGCCATGCTCAGAGTTTTAGGCCTGCTGGATGTTTTCTGTCGTCATGTTTTAGTTGTGCTTTTTAAACCGCTATACGCATttatcttttacattttatttaggatTCTTCACCTCTTTGTTGTTGGTCCAGTAGAGCTCCATTATTCCTGTATAATTTAAGCCTTTTTCTTAGTTGTAGACACACTGTGGTCAGCTCTGTCAGCTCCATGCTGGAGTTTATAAGACAACAGTAAAGGATATTATGACTTTCTACATGTTGACTTTCTTGTATCTGTAAAGGTTTCTTTCCCTCCTGAATAATGAGGGGGAAGTAGAGCTGGCAGACGATTAACCACATGCAgaataaagtttgtatttac

Function

symbol description
ctnnb2 Predicted to enable several functions, including alpha-catenin binding activity; cadherin binding activity; and transcription coactivator activity. Involved in canonical Wnt signaling pathway. Acts upstream of or within convergent extension; determination of dorsal identity; and dorsal/ventral axis specification. Located in nucleus. Is expressed in corneal endothelium; interneuromast cell; neuromast; and secondary posterior lateral line primordium. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); nephroblastoma; and pilomatrixoma. Orthologous to human CTNNB1 (catenin beta 1).

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0048263 determination of dorsal identity biological_process
GO:0009950 dorsal/ventral axis specification biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0060026 convergent extension biological_process
GO:0007155 cell adhesion biological_process
GO:0005912 adherens junction cellular_component
GO:0005634 nucleus cellular_component
GO:0016342 catenin complex cellular_component
GO:0035257 nuclear hormone receptor binding molecular_function
GO:0005515 protein binding molecular_function
GO:0003713 transcription coactivator activity molecular_function
GO:0019903 protein phosphatase binding molecular_function
GO:0045294 alpha-catenin binding molecular_function
GO:0045296 cadherin binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-2575 Predicted to enable several functions, including alpha-catenin binding activity; cadherin binding activity; and transcription coactivator activity. Involved in canonical Wnt signaling pathway. Acts upstream of or within convergent extension; determination of dorsal identity; and dorsal/ventral axis specification. Located in nucleus. Is expressed in corneal endothelium; interneuromast cell; neuromast; and secondary posterior lateral line primordium. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); nephroblastoma; and pilomatrixoma. Orthologous to human CTNNB1 (catenin beta 1).

Ensembl:

ensembl_id ENSDARG00000023472

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00029665 True 3538 mRNA 0.56 16 47975916 47997424

Neighbor

gene id symbol gene type direction distance location
XLOC_015066 NA coding downstream 42982 47931898 ~ 47932934 (-)
XLOC_015065 ago4 coding downstream 143063 47800550 ~ 47832853 (-)
XLOC_015064 cdca8 coding downstream 193000 47771659 ~ 47782916 (-)
XLOC_015063 NA coding downstream 214425 47760897 ~ 47761491 (-)
XLOC_015062 CABZ01071972.1 coding downstream 388197 47578811 ~ 47587719 (-)
XLOC_015068 zgc:158376 coding upstream 6267 48003691 ~ 48015928 (-)
XLOC_015069 NA coding upstream 20282 48017706 ~ 48024071 (-)
XLOC_015070 csf3b coding upstream 40374 48037798 ~ 48039506 (-)
XLOC_015071 NA coding upstream 187874 48185298 ~ 48186157 (-)
XLOC_015072 NA coding upstream 240226 48237650 ~ 48241837 (-)
XLOC_014711 CR382300.3 misc downstream 28247161 19728690 ~ 19728755 (-)
XLOC_015061 CU695215.1 non-coding downstream 408068 47567713 ~ 47567848 (-)
XLOC_015055 CU929178.1 non-coding downstream 559511 47415590 ~ 47416405 (-)
XLOC_015054 CU929178.2 non-coding downstream 575609 47400189 ~ 47400307 (-)
XLOC_015075 NA non-coding upstream 331124 48328548 ~ 48330301 (-)
XLOC_015076 NA non-coding upstream 336664 48334088 ~ 48336535 (-)

Expression


Co-expression Network