XLOC_015209 (ripk2)


Basic Information

Item Value
gene id XLOC_015209
gene name ripk2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 7557912 ~ 7587660 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00030529
TCTCCAAGCGCGAGCTGTAGCACTCATTTCTTTTCCATCTGTTATTCACTGACACTTTTAACAAGGTGTCAGCGGACATGTACCCTTCTCTGGGGGATCTAGTACGTAGGCTGGACCGCATTCACAACATGTAGATACAAGCGtgatttctctttctctctctgcgtAACAGTGCGCTTTCAGTTCCCCTTTTTAGTGAAGCAAAAACGGGCCCGTGTCTTCTCCTAATGTCCAGAAACATGGAGCACACCGGCTGCGTCAACATCTGCAGTCTCACCAGCACATTACCGGTGATCCCGTATCGGAAACTAACGGACCTGCACTACATCAGCAAGGGAGGCTTCGGGACGGTGTTCAGGGCGCAGCACAGTGACTGGCGCACCACAGTGGCGATTAAGTGCTTGAAACTGGATTCACCGGTTGGTGAGAGggAAAGAAATTGTTTACTGAAGGAAGCTGAAGTGCTTCACAAAGCTCGATTTAACCACATCATCCAGATCTTTGGGGTGTGTAATGAACCCGAGTTCTTTTGCATCATAACCGAGTACATGACCAACGGATCGCTGGATGAGCTCCTACATGAGAAGGATATATACCCAGCGGTGGCTTGGCCTTTGAGACTTCGTATACTTTATGAGATTGCTCTTGGAGTCAATTTCCTCCACAATATGTCTCCGCCACTTCTACACCACGATCTCAAAACTCAGAACATCCTGATGGATGGGGAGTACCATGTTAAGATTGCCGATTTTGGCTTGTCTAAATGGCGTCAGCTCTCGATCACCAAAGGCTCTGGCTCCAAACCTGCTGAAATGGGAGGCACAGTCATCTATATGCCACCTGAGGAGTACGAACCCTCCAAAACCCGCAGAACCGATGTCAAGTATGACATGTACAGTTACGCCATCATCATGTGGGAAGTGCTGTCGAGACGAATACCATTTGAAGAGGCCACCAATCCCATGCAGATCATGTTCAGCGTTCTCCGAGGCGCTCGACCTGACACAGGCCTGGACAGTCTGCCGGTAGACATTCCCAGTCGAGAGACTCTCATTAACCTTATGACCAGCGGCTGGACCGCCAACCCAGATGAACGGCCTTCTTTTCTCCATTGTCTTATTGAACTGGAGCCCATGTTGAGAAGATTTGATGAGATTGATGTCTTGGAAGCAGTGTTGGAGGTCAAAAGAATAAAGTACAGGAGGCCGTCAAGCTGCTGCTCATCGACTCAAAGTAACGGAAAGAAAATTGAGGAAAAGTGTGTGAAAGAGCTAAATGTCCCATGGCCAGACAACAGTTCCACATCTGGATCAGGCTCCTGCTCTTCCCAGGAAGCAGAAATATCCCAGCCGGGCTTCCTTACCATATCAACTCCCTCTCAAGGTGCTTATGCGGGTCTGCCGTCATCATTAATGTCTCTTCCACTGGATCCCCCAAAGCCTCTTATGGACAACTGCTCTCCCAACAACCTGAGTCCTGAATATCAGACAGCGCAGGTCGTGTCAGACCTCAACATACCATTCAAAGCTCATGCGCCTCAGAGTGAAAGTGAGCTGGCTCTTGCCATACAACCCCTCACACTGCATCCACACCCACAA

Function

symbol description
ripk2 Predicted to enable CARD domain binding activity and JUN kinase kinase kinase activity. Acts upstream of or within antibacterial innate immune response; defense response to virus; and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm. Is expressed in brain; gill; liver; pleuroperitoneal region; and unfertilized egg. Orthologous to human RIPK2 (receptor interacting serine/threonine kinase 2).

GO:

id name namespace
GO:0002250 adaptive immune response biological_process
GO:0045087 innate immune response biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0042742 defense response to bacterium biological_process
GO:0007257 activation of JUN kinase activity biological_process
GO:0043065 positive regulation of apoptotic process biological_process
GO:0002376 immune system process biological_process
GO:0006468 protein phosphorylation biological_process
GO:0051607 defense response to virus biological_process
GO:0016310 phosphorylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0050700 CARD domain binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004706 JUN kinase kinase kinase activity molecular_function

KEGG:

id description
ko04621 NOD-like receptor signaling pathway
ko04722 Neurotrophin signaling pathway
ko05132 Salmonella infection
ko05131 Shigellosis
ko05152 Tuberculosis
ko01001 Protein kinases

ZFIN:

id description
ZDB-GENE-030902-3 Predicted to enable CARD domain binding activity and JUN kinase kinase kinase activity. Acts upstream of or within antibacterial innate immune response; defense response to virus; and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm. Is expressed in brain; gill; liver; pleuroperitoneal region; and unfertilized egg. Orthologous to human RIPK2 (receptor interacting serine/threonine kinase 2).

Ensembl:

ensembl_id ENSDARG00000104290

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00030529 True 1598 mRNA 0.49 10 7557912 7587660
Loading

Neighbor

gene id symbol gene type direction distance location
XLOC_015208 NA coding upstream 28855 7526842 ~ 7529057 (+)
XLOC_015207 NA coding upstream 43731 7511477 ~ 7514181 (+)
XLOC_015205 si:dkeyp-106c3.1 coding upstream 145331 7295515 ~ 7412581 (+)
XLOC_015206 CU929374.1 coding upstream 163004 7394790 ~ 7394908 (+)
XLOC_015204 si:dkeyp-106c3.3 coding upstream 271603 7279646 ~ 7286309 (+)
XLOC_015210 NA coding downstream 25506 7613166 ~ 7614060 (+)
XLOC_015211 NA coding downstream 60203 7647863 ~ 7654618 (+)
XLOC_015212 NA coding downstream 69638 7657298 ~ 7662101 (+)
XLOC_015213 NA coding downstream 128132 7715792 ~ 7727248 (+)
XLOC_015214 CT027646.3 coding downstream 133279 7720939 ~ 7721009 (+)
XLOC_015203 NA non-coding upstream 294701 7261348 ~ 7263211 (+)
XLOC_015200 NA non-coding upstream 402721 7149154 ~ 7155191 (+)

Expression

Expression of XLOC_015209(ripk2) in the Zebrafish Sample from each Developmental Stage of PRJEB12982

Boxplot with 18 boxes. Box plot charts are typically used to display groups of statistical data. Each data point in the chart can have up to 5 values: minimum, lower quartile, median, upper quartile, and maximum.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying Expression. Range: 0 to 75.
End of interactive chart.

Expression of XLOC_015209(ripk2) in the Zebrafish Sample of PRJEB12982

Bar chart with 360 bars.
The chart has 1 X axis displaying categories.
The chart has 1 Y axis displaying Expression. Range: 0 to 75.
End of interactive chart.

Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000004_00380887_00400711 RIPK2 coding CI01000004 null 379977 ~ 401457 (-)