XLOC_015271 (cdc73)


Basic Information

Item Value
gene id XLOC_015271
gene name cdc73
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 11946554 ~ 12003175 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00030625
CATGGCGGACGTGTTGAGTGTTCTTCGCCAGTACAACATCCAGAAAAAGGAGATTGTCGCAAAAGGCGATGAAGTTATTTTCGGGGAATTCTCCTGGCCTAAAAATGTCAAGACCAACTATGTCATCTGGGGAACTGGAAAAGAGGGACAACCTAAAGAGTACTACACTCTTGATTCCATTCTCTTCCTGCTTAACAATGTCCATCTTCCTCACCCCTCCTATGTGCGGAGAGCTGCAACAGAAAACATCCCTGTTGTCAGGCGACCCGACAGAAAAGACTTGCTGTCTTATCTAAATGGAGAAAGCTCATCATCAACGAGTATCGACAGAAGTGCACCTATAGAGATAGGTCTACAAAGGCCAACACAAGtTAAAAGGGCAGCAGATGAAGTTTCGTCAGAAGCAAAAAAGCCTCGGGTTGAAGATGAAGAGCGTGTGCGTCTGGATAAGGAGCGTCTGGCTGCTCGTCTCGAGGGTCATAAGGAAAGCATTGTGCAGACAGATCAGATCAGGTCTCTTTCTGAAGCTATGTCTGTGGAGAAGATCGCTGCTATCAAGGCTAAAATCATGGCCAAGAAGCGCTCCACTATCAAGACTGACCTGGACGATGACATCACCCAGAAACAGAGAAGCTTTGTGGATGCAGAAGTGGATGTGACCAGAGACATTGTGAGTCGAGAGAGAGTCTGGCGGACGAGGACAACCATTTTACAGAGCAGCGGCAAGaacTTTTCCAAAAATATATTTGCCATCTTACAATCAGTGAAGGCACGAGAGGAAGGTCGAGCCCCTGAACAGAGACAGACTCAGAATCAAACTCAGGTGGATCCAGCAATAAGAAATAAACAGCCAGTCCCAGCTGCCTACAACAGATATGACCAGGAGCGATTCAAAGGGAAAGAGGaaacGGAGGGTTTTAAAATTGACACTATGGGAACCTATCACGGTATGACGCTGAAGTCGGTGACGGAAGGAGCATCTGCTAGAAAAGCCCAAACACCAGCTATGCAGCCTGTTCCCAGACCAGtctcTCAAGCAAGACCCCCACCAAACCAAAAGAAAGGTTCAAGAACTCCTATTATCATCATCCCTGCAGCTACAACATCTTTAATCACAATGCTCAATGCCAAGGATCTCTTACAGGACCTCAAGTTTGTCACATCAGAGGAAAAGAAGAAGCAGGGCATTCAGAGGGACAACGAAGTTCTTCTACAGAGACGTAAAGATCAGGTCCAACCTGGCGGTGCCACGCTCAGCGTCACTGTACCCTACAGAGTGATCGACCAGCCACTCAAACTGGCCCCGCAGGACTGGGATCGTGTTGTGGCGGTCTTCGTTCAGGGTCCTGCCTGGCAGTTCAAGGGCTGGCCGTGGCTACTGCCCGATGGATCCCCAGTGgacatatttgccaaaaTTCGAGCCTTTCACCTGAAGTACGATGAGGCACGGATGGACCCAAACGTGCAGAAGTGGGACGTGACTGTGCTGGAGCTGAGCCACCACAAACGACACTTGGACCGGCCCGTCTTCCTGCGCTTCTGGGAAACACTTGACAGGTCAGGATgaaatgtgaaatgtttttttgttatgaAATTTTAGCGCTTccataacaataaacaaatttttgtgtatttttctgGCTGCCAACAGATATCTCAATGTAATGATATCTTACAAATCATTAATACTAATAAATGATTTTTTCGTAGATGATAGatatcacacgcacacacacacccattcttagaaaaggaatggcattcatttcaaataaaagcaGATGCACTCCA
>TCONS_00030626
CATGGCGGACGTGTTGAGTGTTCTTCGCCAGTACAACATCCAGAAAAAGGAGATTGTCGCAAAAGGCGATGAAGTTATTTTCGGGGAATTCTCCTGGCCTAAAAATGTCAAGACCAACTATGTCATCTGGGGAACTGGAAAAGAGGGACAACCTAAAGAGTACTACACTCTTGATTCCATTCTCTTCCTGCTTAACAATGTCCATCTTCCTCACCCCTCCTATGTGCGGAGAGCTGCAACAGAAAACATCCCTGTTGTCAGGCGACCCGACAGAAAAGACTTGCTGTCTTATCTAAATGGAGAAAGCTCATCATCAACGAGTATCGACAGAAGTGCACCTATAGAGATAGGTCTACAAAGGCCAACACAAGtTAAAAGGGCAGCAGATGAAGTTTCGTCAGAAGCAAAAAAGCCTCGGGTTGAAGATGAAGAGCGTGTGCGTCTGGATAAGGAGCGTCTGGCTGCTCGTCTCGAGGGTCATAAGGAAAGCATTGTGCAGACAGATCAGATCAGGTCTCTTTCTGAAGCTATGTCTGTGGAGAAGATCGCTGCTATCAAGGCTAAAATCATGGCCAAGAAGCGCTCCACTATCAAGACTGACCTGGACGATGACATCACCCAGAAACAGAGAAGCTTTGTGGATGCAGAAGTGGATGTGACCAGAGACATTGTGAGTCGAGAGAGAGTCTGGCGGACGAGGACAACCATTTTACAGAGCAGCGGCAAGaacTTTTCCAAAAATATATTTGCCATCTTACAATCAGTGAAGGCACGAGAGGAAGGTCGAGCCCCTGAACAGAGACAGACTCAGAATCAAACTCAGGTGGATCCAGCAATAAGAAATAAACAGCCAGTCCCAGCTGCCTACAACAGATATGACCAGGAGCGATTCAAAGGGAAAGAGGaaacGGAGGGTTTTAAAATTGACACTATGGGAACCTATCACGGTATGACGCTGAAGTCGGTGACGGAAGGAGCATCTGCTAGAAAAGCCCAAACACCAGCTATGCAGCCTGTTCCCAGACCAGtctcTCAAGCAAGACCCCCACCAAACCAAAAGAAAGGTTCAAGAACTCCTATTATCATCATCCCTGCAGCTACAACATCTTTAATCACAATGCTCAATGCCAAGGATCTCTTACAGGACCTCAAGTTTGTCACATCAGAGGAAAAGAAGAAGCAGGGCATTCAGAGGGACAACGAAGTTCTTCTACAGAGACGTAAAGATCAGGTCCAACCTGGCGGTGCCACGCTCAGCGTCACTGTACCCTACAGAGTGATCGACCAGCCACTCAAACTGGCCCCGCAGGACTGGGATCGTGTTGTGGCGGTCTTCGTTCAGGGTCCTGCCTGGCAGTTCAAGGGCTGGCCGTGGCTACTGCCCGATGGATCCCCAGTGgacatatttgccaaaaTTCGAGCCTTTCACCTGAAGTACGATGAGGCACGGATGGACCCAAACGTGCAGAAGTGGGACGTGACTGTGCTGGAGCTGAGCCACCACAAACGACACTTGGACCGGCCCGTCTTCCTGCGCTTCTGGGAAACACTTGACAGATACATGGTCAAACACAAGTCCCACCTGAGGTTCTGAGAGCGCTGGCCGTACACCCATCAACACATCGAGGCCGTCGAGATGTTCCCTCCCTCCAAAGACGTGTCACGATGGACTGCTAGACCCCTCATTTCTCTCAAACCCCCCCTGAAAGCACTTGAGATTTCAGTACGCTTCTCCTTCTGCTGACACCAGTATGATTTGTAGTCTCTTCCTCCACTGTAGATGAGCAGGTCAGGGTGGGCGAGGGGAACTTTGGGTTGGTTCTTGTCATGTTTTCTGAGTAGATATGTATTTTTCAATTGTAAAGCAGTTGGTAATCAAGGCAGTTTcagaagtttttgttttttttgttatccagctcaagctaaaaaaaaaaaagttaaactgagAACCGTTAAAAATGGTGACTCGATGATCTGAATAAAATGACTGCTAAGAGCTCTTGTAATGataaattgtttatttctttctcttttataattttttttctgccttCTGTTCTATGAAGTGTAGAGTAGTGCATTAACCTTCACTGCACAAATGCAAAAGATAAATATATCAGATTATGCCTCTGGGTTAAGGATAAAGTGAATTTAAAAGCAAACAGGACCACAGACGTAAATATCCACAGTGCTTTGGTTAcgaataaatctgtattttagaTTGTTCATGGTGGATATTTTCTGTAATTCCGCAGTATTGGAAATTTTGTTCAAGTTTTACCCAAAAATTCAAGTACCGCTTGCATCTAATTGCTGTTTTGTTTAATGGACACTGCATTTACATCCATAAGGCAAAGTCAAATATTCACAAGGGtacaatttcttttcttttttactttttttttttttttttgttttttgaatggcTGTTTTTTTGTATAAATGCGTTTGAaagtaatgtttgtttttaaacatttctgttcaatgtggattattaaaaaattacaaaaaagta

Function

symbol description
cdc73 Predicted to enable RNA polymerase II complex binding activity. Involved in heart development. Acts upstream of or within erythrocyte differentiation; regulation of transcription elongation from RNA polymerase II promoter; and spinal cord oligodendrocyte cell differentiation. Located in nucleus. Part of Cdc73/Paf1 complex. Human ortholog(s) of this gene implicated in hyperparathyroidism and parathyroid carcinoma. Orthologous to human CDC73 (cell division cycle 73).

GO:

id name namespace
GO:0021529 spinal cord oligodendrocyte cell differentiation biological_process
GO:0007507 heart development biological_process
GO:0006368 transcription elongation from RNA polymerase II promoter biological_process
GO:0034243 regulation of transcription elongation from RNA polymerase II promoter biological_process
GO:0030218 erythrocyte differentiation biological_process
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter biological_process
GO:0007049 cell cycle biological_process
GO:0016570 histone modification biological_process
GO:0051301 cell division biological_process
GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex biological_process
GO:0005634 nucleus cellular_component
GO:0016593 Cdc73/Paf1 complex cellular_component
GO:0000993 RNA polymerase II complex binding molecular_function

KEGG:

id description
ko03021 Transcription machinery

ZFIN:

id description
ZDB-GENE-040426-1309 Predicted to enable RNA polymerase II complex binding activity. Involved in heart development. Acts upstream of or within erythrocyte differentiation; regulation of transcription elongation from RNA polymerase II promoter; and spinal cord oligodendrocyte cell differentiation. Located in nucleus. Part of Cdc73/Paf1 complex. Human ortholog(s) of this gene implicated in hyperparathyroidism and parathyroid carcinoma. Orthologous to human CDC73 (cell division cycle 73).

Ensembl:

ensembl_id ENSDARG00000020201

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00030625 False 1791 mRNA 0.47 16 11946554 11998297
TCONS_00030626 True 2515 mRNA 0.44 17 11946554 12003175

Neighbor

gene id symbol gene type direction distance location
XLOC_015270 ro60 coding upstream 618 11923615 ~ 11945936 (+)
XLOC_015269 greb1l coding upstream 113198 11685742 ~ 11833356 (+)
XLOC_015268 ftr01 coding upstream 268849 11670270 ~ 11677705 (+)
XLOC_015267 BX890600.1 coding upstream 297716 11648163 ~ 11648838 (+)
XLOC_015266 NA coding upstream 313231 11629002 ~ 11633323 (+)
XLOC_015272 prtfdc1 coding downstream 252393 12255568 ~ 12280508 (+)
XLOC_015273 arhgap21b coding downstream 299352 12302527 ~ 12406641 (+)
XLOC_015274 NA coding downstream 632752 12635927 ~ 12637877 (+)
XLOC_015275 BX908750.1 coding downstream 795191 12798366 ~ 12802906 (+)
XLOC_015276 kmt2cb coding downstream 844427 12847602 ~ 13037544 (+)
XLOC_015265 BX901918.1 non-coding upstream 702547 11243886 ~ 11244007 (+)
XLOC_015261 CR450845.1 non-coding upstream 939764 11006657 ~ 11006790 (+)
XLOC_015254 NA non-coding upstream 1339225 10604513 ~ 10607329 (+)
XLOC_015279 BX511000.1 non-coding downstream 1120391 13123566 ~ 13123682 (+)
XLOC_015280 NA non-coding downstream 1344225 13347400 ~ 13351299 (+)
XLOC_015285 NA non-coding downstream 1946883 13950058 ~ 13958576 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00005185 cdc73,LOC101483205,LOC105941386,LOC106633477 coding CM030140.1 CM030140.1 18011528 ~ 18022231 (-)