XLOC_015818 (si:ch211-195h23.3)


Basic Information

Item Value
gene id XLOC_015818
gene name si:ch211-195h23.3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 43920461 ~ 43955410 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00031444
AACAAATCTATTGACGATAGCGCGTGTGTTCTAGGCAGATTTTCACGCGAAGTTCCTGGTAATGAGCATGCCGTGCTGAAATTGAGATCCATAGATGGAGTCTTCGCAAAGTGACGAATGCATGTCAGATTCAGAAGACGAGGGGGAATGCACATCAGATTCAGATGACGAGAGGGGGATGCGTATATCATTATCAGATTCAGATGACGAGTCCACTTCGAAACGACGTTTTAGGCACCCAAGAAGCTTAAGCATGGGCACAAGATCGAGGACAGTTAAACGCCATAGATTTCACAGGTTACAGGCTTCCAAAAAAACTGAAACTGTTTTGGAGCATGTGGATGGTGCAGAATCATCTTCAGGACAAACACCCTCAGATGATGCAGAAATATTCACACCTGAACTTATTCAAGAAGATGACAAGTACAAAGACAAGAATACATACAGgtttgtttgtcCTCATGCTGGTCAGTTTCAGTGCAGTCTGACCAGTCTTGTGTTTGTGATGGATGGTGAAGGAGAGCTGCTGTATAGAGTCGTCTCGTGGGATCCTCGTCTTTTAGATGGTTTGGGTCAAATGCAGCCTGCAGGACCCTTATATGACGTTAAATGTTTTAATGGCTCAATCTCAAAACTGCACCTTCCTCACTGTGAAATATTCTCTGAGGGCGACAACATGGATGGATTGGCTGTAGCACATTTCACTGGAGGGAATATGGAAATAGTGCAGCCAATTACAGTGACAGAAACCCACGTGATGATTGACATCAGAGATCTCTCTCTATTTGGACTCCTCTGGATGAAGATATTTAGTCACCCCATTAGTGGACAAGTTTTGCTTTTCCTTCGAACACTACCTGTtgaagaggaagaagaggaagagaaaaTACTGAATGTTCACTTGCTTCCAGGGAATGTTCCTGTGTCAGAGGTCGTGCACTCGCACCAGGATAAAAAATACATTGAGACAACTTCAAAATGTCATTTGTTTCTTGAGCGGGAATACAGTCTACGTTGCCAGCCAGAGAACTGTGAAGTGCAACCGAAGagcGAGATCTTTGAGCATAATAATTTTGGTCCAAACTTCCATCCCTCATTTCAAGTGTTTTTGAGTGTTGACGTTAAAAAGGTTGGATTGACTATTTTAGACAAAGCTGAAGATTGTAAGGAAGTGTGGAGCCGACCACGAGTATCACTTAAAGCACCAAGTCAAGGAGTAGAACCTCCAGAGCACAGAATGATTTCAgGAAGTGAATTTGTGGATGCCCTCAGAGGTAAACTCATTCAGAGAGTTTCATCAGTGATGGCGATTGCTGACAGCCTGAGGAGCAAACACATGATTACAGATGAATTATACAGCGAACTTCATAATGCCGATACAAATCAGAGGAAAATGAGATGCCTGTTTATGGCTCTGGACTCTGGAGGAGCTTCTGTGAAAGCAGAGTTTTACCGTCTGCTAAAGAAGAACGAACCTCATCTAGTAGAGGAACTGGAGTCTGGACACAGCAAATCCTTCAGACGTCAGTAATGCTGagagtaagggtgctttcacacctgtgaatcgattcagttgttccgaaacagagattacaattgttacattgttgctctttactcttggagcggttcgctttcacactgcaaagtttctaatcggaccaaaagagctaaaacaagtcacgtgcgagtaaactctccttacattggtcagagtgtcagggtttattttgcagcgtctcGCTAAACTGTCAGGacaggtggtggtttggtggtgattgacagggtgcgcgcgtgtgacgtgtctgaggagagatgcggtggggaggg

Function

symbol description
si:ch211-195h23.3 Predicted to enable cysteine-type endopeptidase activity involved in apoptotic signaling pathway and cysteine-type endopeptidase activity involved in execution phase of apoptosis. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity. Located in nucleus. Is expressed in kidney and spleen. Human ortholog(s) of this gene implicated in inflammatory bowel disease 30. Orthologous to human CARD8 (caspase recruitment domain family member 8).

GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0006915 apoptotic process biological_process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0032088 negative regulation of NF-kappaB transcription factor activity biological_process
GO:0006954 inflammatory response biological_process
GO:0006508 proteolysis biological_process
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004197 cysteine-type endopeptidase activity molecular_function
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process molecular_function
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway molecular_function
GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070912-174 Predicted to enable cysteine-type endopeptidase activity involved in apoptotic signaling pathway and cysteine-type endopeptidase activity involved in execution phase of apoptosis. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity. Located in nucleus. Is expressed in kidney and spleen. Human ortholog(s) of this gene implicated in inflammatory bowel disease 30. Orthologous to human CARD8 (caspase recruitment domain family member 8).

Ensembl:

ensembl_id ENSDARG00000068431

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00031444 True 1830 mRNA 0.44 13 43920461 43955410

Neighbor

gene id symbol gene type direction distance location
XLOC_015817 gbp3 coding upstream 1587 43894368 ~ 43918874 (+)
XLOC_015816 nlrb5 coding upstream 49074 43851983 ~ 43871387 (+)
XLOC_015815 arhgap12a coding upstream 123243 43749221 ~ 43797218 (+)
XLOC_015814 NA coding upstream 261177 43653620 ~ 43659284 (+)
XLOC_015813 nrp1b coding upstream 413183 43469241 ~ 43507278 (+)
XLOC_015820 zgc:152670 coding downstream 393063 44348473 ~ 44362943 (+)
XLOC_015821 BX005060.1 coding downstream 417811 44373221 ~ 44386693 (+)
XLOC_015822 NA coding downstream 427762 44383172 ~ 44385238 (+)
XLOC_015823 NA coding downstream 439904 44395314 ~ 44400668 (+)
XLOC_015824 kcnab1b coding downstream 471199 44426609 ~ 44510752 (+)
XLOC_015811 NA non-coding upstream 756943 43138555 ~ 43163518 (+)
XLOC_015809 NA non-coding upstream 910080 42972927 ~ 43010381 (+)
XLOC_015810 BX511268.1 non-coding upstream 921542 42998802 ~ 42998919 (+)
XLOC_015807 BX005083.1 non-coding upstream 1139207 42773349 ~ 42781254 (+)
XLOC_015827 BX323035.2 non-coding downstream 608968 44564378 ~ 44564494 (+)
XLOC_015832 NA non-coding downstream 1029073 44984483 ~ 44989293 (+)

Expression


Co-expression Network