XLOC_015824 (kcnab1b)


Basic Information

Item Value
gene id XLOC_015824
gene name kcnab1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 44426609 ~ 44510752 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00031450
ATGCAGGTGTCATTCGCATGTACGGATCATGGGTTGAAGGCCCCGCGCACCAGCGAGCCAAACAAGCAGAACACGTCCAGTCCCAACACGGCAAGCGCAGCCCGGGCACGCTTCCGGACGGTGGCTCTGATCGCTCGCAGCCTGGGCTCCTTCACGCACAGGCACCACATTTCCCTGAAGGAGTCCACTGGGAAACTCACTGGCATGAAGTACAGGTATGGAAAATCCCTGACAACTCCCAGAAAAAGtatatgcACATGGGTGACATTTGGGGGACAGATCTCAGATGAGgtTGCAGAGCAGCTGATGACTATAGCCTATGAAAATGGGGTGAATCTCTTTGACACTGCAGAGGTCTACTCAGCTGGCAAGGCTGAAATAATCCTAGGAAACATTATCAAGAAGAAGTGCTGGAGGAGATCCAGTCTGGTTATCACCACTAAACTCTACTGGGGAGGAAAGTTACAGCTGGATTATGTGGATGTGGTTTTTGCCAACCGCCCTGACAGCAACACACCTATGGAGGagataGTGAGAGCCATGACTCATGTCATTAATCATGGCATGTCCATGTACTGGGGCACGTCCCGCTGGTCAGCTATGGAGATTATGGAGGCGTATTCTGTAGCGAGGCAGTTTAATCTGATTCCTCCTGTGTGTGAACAAGCCGAGTATCATTTATTTCAGAGGGACAAAGTGGAGATGCAACTACCAGAGCTTTACCACAAAATTGGTGTTGGTGTGGTGTCCTGGTCTCCTTTGGCCTGCGGCATCATCACAGGAAAATATGAAAACGGCATCCCAGAATCCTCCAGAGCCTCTATGAAGTCATATCAGTGGTTAAAGGAGAAGATTCTAGGTGAGGATGGCAGAAAGCAGCAGGCCAAGCTTAAGGAATTGACCCACATCGCTGAGCGGCTCAGTTGTACGCTGCCACAACTTGCCATCGCTTGGTGCCTCCGTAATGAAGGAGTAAGTTCTGTTCTCCTGGGGACCTCAAACCCTGCGCAACTCACAGAGAACCTGGGGGCGATTCAGGTTCTTCCAAAGATTACCGCTCACGTGGCCTCGGACATCGATAAAATCCTGGGAAATCGTCCGCACAGTAAGAAGGACTACCATCACTAG
>TCONS_00031451
ATGCAGGTGTCATTCGCATGTACGGATCATGGGTTGAAGGCCCCGCGCACCAGCGAGCCAAACAAGCAGAACACGTCCAGTCCCAACACGGCAAGCGCAGCCCGGGCACGCTTCCGGACGGTGGCTCTGATCGCTCGCAGCCTGGGCTCCTTCACGCACAGGCACCACATTTCCCTGAAGGAGTCCACTGGGAAACTCACTGGCATGAAGTACAGGAATCTTGGAAAGTCTGGACTGCGGGTGTCATGCCTTGGACTCGgcACATGGGTGACATTTGGGGGACAGATCTCAGATGAGgtTGCAGAGCAGCTGATGACTATAGCCTATGAAAATGGGGTGAATCTCTTTGACACTGCAGAGGTCTACTCAGCTGGCAAGGCTGAAATAATCCTAGGAAACATTATCAAGAAGAAGTGCTGGAGGAGATCCAGTCTGGTTATCACCACTAAACTCTACTGGGGAGGAAAGGCAGAGACAGAGCGTGGGCTTTCGAGGAAGCACATCATTGAAGGTCTGAAGGGCTCTTTGCAGAGGTTACAGCTGGATTATGTGGATGTGGTTTTTGCCAACCGCCCTGACAGCAACACACCTATGGAGGagataGTGAGAGCCATGACTCATGTCATTAATCATGGCATGTCCATGTACTGGGGCACGTCCCGCTGGTCAGCTATGGAGATTATGGAGGCGTATTCTGTAGCGAGGCAGTTTAATCTGATTCCTCCTGTGTGTGAACAAGCCGAGTATCATTTATTTCAGAGGGACAAAGTGGAGATGCAACTACCAGAGCTTTACCACAAAATTGGTGTTGGTGTGGTGTCCTGGTCTCCTTTGGCCTGCGGCATCATCACAGGAAAATATGAAAACGGCATCCCAGAATCCTCCAGAGCCTCTATGAAGTCATATCAGTGGTTAAAGGAGAAGATTCTAGGTGAGGATGGCAGAAAGCAGCAGGCCAAGCTTAAGGAATTGACCCACATCGCTGAGCGGCTCAGTTGTACGCTGCCACAACTTGCCATCGGTTCTTCCAAAGATTACCGCTCACGTGGCCTCGGACATCGATAAAATCCTGGGAAATCGTCCGCACAGTAAGAAGGACTACCATCACTAGGCCTTTCTGTGAACCTGTAAGCCTTGAGACTCAGGATCCCGATTCAGCCCTCGTGTGTCGGCAGTGTGTGATTCCCACTGTCTTCTGTCCACTTCTCCCTGCAGAGAGCTGTTGTTACCGTTACAGTAGAAATGCTAAAGTGTTATGCATGCTTCTGTTCGACCTAAACCTGAGCTCAACCTTGCATTAAGATGTCTGTGGAGATAGACGCACATGCCTGTGAAGCACAAAAGCTCCCTCATCTGCGAGCTTTTGCATTCAGCTGTCCATCACCCATATGTGCCAAAGTAAACCTGGTCTTGACCCTTGACCTCCGGACAACCATTCTGAAAAGGCTCTGAATActgtctagaaaaaaaaaacacaatgaaatgAGGGAAATAAAGAAAGGAAAGTGCACCGAGAATGTAAAAACTGTGACGTATTACAGAGCTGCGAGTACTTTGTAAGATGTGTGCATTGGTATGTTGGATTAAAAAGCCATCAACAGCGAAGTGGGctgtttttgtgtttaaatgttgCTCCCACCATCTTGTTaagactgtttgtgtgtgttaccTCTGCAATTTGTGTCATGTCTAATCAGTACAATAATTTCTTACTTCTCAAGTCATTTCAAAAGAATAATATAAAAgaagtttagtttattcaaatgcTTTTCCAGTGATAAAGTTTCACTTTATTAACGACTGGTTAAAGACTTAAATGCTTGCTGCTGTATTTGGTCACTTCTGAACTGTTAAGCAGTACATACTTGAGTCCAGAGAGTTGATAGAAATGCACAACTACTGTAAACATCTAGTAAATAAGGtactatatgaaataaaatagggTCAAAATGTTTACAAACTTGAAAATAATGAAgctgttaattaatgcattatgtcGAGTGCTTTAAcatctaaataaaaaatgtgcatcTA

Function

symbol description
kcnab1b Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in female organism. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1).

GO:

id name namespace
GO:0055085 transmembrane transport biological_process
GO:1901379 regulation of potassium ion transmembrane transport biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0006813 potassium ion transport biological_process
GO:1902260 negative regulation of delayed rectifier potassium channel activity biological_process
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane cellular_component
GO:0044224 juxtaparanode region of axon cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004033 aldo-keto reductase (NADP) activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0044325 ion channel binding molecular_function
GO:0015459 potassium channel regulator activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070912-690 Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in female organism. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1).

Ensembl:

ensembl_id ENSDARG00000040741

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00031450 False 1128 mRNA 0.51 12 44426609 44509829
TCONS_00031451 True 2034 mRNA 0.45 13 44426609 44510752

Neighbor

gene id symbol gene type direction distance location
XLOC_015823 NA coding upstream 25941 44395314 ~ 44400668 (+)
XLOC_015821 BX005060.1 coding upstream 39916 44373221 ~ 44386693 (+)
XLOC_015822 NA coding upstream 41371 44383172 ~ 44385238 (+)
XLOC_015820 zgc:152670 coding upstream 63666 44348473 ~ 44362943 (+)
XLOC_015818 si:ch211-195h23.3 coding upstream 471199 43920461 ~ 43955410 (+)
XLOC_015825 pask coding downstream 1572 44512324 ~ 44545869 (+)
XLOC_015826 MTERF4 coding downstream 35160 44545912 ~ 44557318 (+)
XLOC_015827 BX323035.2 coding downstream 53626 44564378 ~ 44564494 (+)
XLOC_015828 klhl24a coding downstream 60448 44571200 ~ 44604455 (+)
XLOC_015829 yeats2 coding downstream 104248 44615000 ~ 44693315 (+)
XLOC_015819 NA non-coding upstream 490477 43935376 ~ 43936132 (+)
XLOC_015814 NA non-coding upstream 767325 43653620 ~ 43659284 (+)
XLOC_015832 NA non-coding downstream 473731 44984483 ~ 44989293 (+)
XLOC_015843 NA non-coding downstream 921830 45432582 ~ 45433628 (+)
XLOC_015846 NA non-coding downstream 950381 45461133 ~ 45461974 (+)
XLOC_015847 NA non-coding downstream 957315 45468067 ~ 45468585 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000152_01617420_01635268 KCNAB1A, KCNAB1B, KCNAB1 coding CI01000152 null 1617420 ~ 1635268 (+)