XLOC_000016 (grk1a)


Basic Information

Item Value
gene id XLOC_000016
gene name grk1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 245076 ~ 258138 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000033
ATCGTCCACTTGTCCATCACACACACTGGATCCATTGGTCCTCCAGCAGATCTCCACATCCAGAGTCTGATGATCTGATCCTGGCCTTTGTCGCTGCGTCCAGTTTGAGCTCCAATGCTCTCGCTGTGACCCGTCAGTCTTCAAGAATCCTCTAGAAAACTTCTGTGTCCTCAACATGGACATCGGCGGCCTCACCACGGTGGTGGCCAACTCTGCCTACATCTCCGCCCGCGGCAGCTTCGATGGCACGGCAAACCCAGCGTCCAACCGAGACAAGAAATACCACTCCAAGCTGAAGCTGCCCCACATCACGGTCTGCGAAGATCTCCGAGAAACCCTGGATCTGCAGTTCAGGAGCATCTGTGTGGAGCAACCCATCGGGAAGAGGCTTTTTCAGGAGTATCTGGAGACCGCCAATGAATACAAGGGCCCCTGCCGCCTGTGGAGGGACGTAGAGGAATACGACACGGCCGAGGATAAAGACCGCACTCAGAAAGCTGCGAAAATCCTCCAGCGCTACATGGAGCCCTCAGCCAAACACTTCTGCCCGTTTCTACCAGAGAATGGCATCACCAAAGTCAAGGAGCGGCATCAGGAGGCGGCGGACGACCTGTTCGTGGAGATCCTGGCCTGCGTCTTTGATTTCCTCAAGGAGGTGCCCTTCACTTTCTATCTAGAGACCATGTACTTTAAGCGCTTCTTGCAGTGGAAGTGGCTGGAGATGCAGCCGGTGGCCGAGGACTGGTTCCTGGACTTCCGTGTTTTGGGAAAAGGAGGATTCGGAGAAGTTTCCGCATGTCAGATGAGGGCCACGGGGAAGCTGTACGCCTGCAAGAAACTCAACAAGAAGAGGCTGAAGAAGAGGAAAGGCTATGAGGGAGCGATGGTGGAGAAGCGTATCCTGGCTCGTGTCCACAGCAGGTTTATCGTGTCTCTGGCCTACGCCTTCCAGACCAAAACTGAGCTGTGTCTGGTGATGACCATCATGAACGGAGGAGACCTCAGGTACCACATCTATAATGTGGATGAGAATAACCCCGGCTTCTCTGAGCCCAGAGCCTGTTATTACGCCGCTCAGATCATCCAGGGCCTGGAGCATCTGCACCAGAAGAAGATCATCTACAGAGACCTCAAGCCGGAGAACGTTCTGCTGGATAATgaagGTAACGTCAGGATCTCTGACCTGGGCTTGGCTGTTGAACTGGCAGACGGACAGGAGAAAACCAAAGGTTATGCTGGAACGCCAGGGTTCATGGCGCCGGAGCTGTTGAAGGGTGAGGAGTATGATTATTCAGTGGATTACTTCACTCTGGGGGTCACGCTGTACGAGTTCATCGCCGCTAAAGGACCCTTCAGGACTCGAGGAGAGAAGGTGGAGAATAAAGAGGTGAAGAAGCGGATCCTGAATGACCCGGTCACATATTCAGAGAAGTTCAGTGAGAACGCTAAGTCCATCTGCGAGGGTCTGCTGGCCAAAGAGGTGGACAAGAGACTGGGCTTCAAGAACGGCACATGTGATGAGATCCGCACACATCCCTTCTTCAGCCAACTCAACTGGAGGAAACTAGAcgcagGTATTCTTCCTCCTCCGTTCGTCCCGGACTCTAAGACGGTCTATGCGAAGGATCTAGATGACGTGGGCGCGTTCTCCACGGTGAAGGGTGTCTGTCTGGAGGATGATGATAAGTGTTTCTTCGATGAGTTTGCGTCAGGGAATATCTCCATTCCATGGCAGGAGGAGATGATCGAGACGGGGATCTACGGCGAGCTGAACGTCTGGGGGCCCGGAGGAGCTGTGCCCAATGACCTGCGCCGGGAGTCCATCCTAGAGCAGCCGCCCAAATCCTCCACCTGCAGCGTCTCCTAATGCACTGTAGCAATGCTGGACCCCGCACagctccttcatgttgtccctgCACTAACCCATCAACAGAACTTAATGGACTCTTTTCACAATTCCAGGTTTCTTataagatgatataatacatgcagaaataataataataataataattcaatacatttatatagcactttactggacactcaaagtgctttacacattggggcgggatttatacatatacatgtattcattcgttgtttgttcattcattcattttcttttcagcttagtccctttattaatcaggggtcaccacagcagaatgaaccgccaacttatccagcatatgttttacacagcagatgcccttccaactgcaacccatcactgggaaacacccatgcacactcattctctctcacacacacacacacacactacagacaatttagcttacccaattccacTATACaaaatgtgtttggactgtggggggaactggagcacctggagggagaacatgcaaactccacagagaaacaccaactgacccagccggggatcgaaccagcgaccttcttgctgtgaggtgattgtgctgcccactgcgccaccgtgctgccattgatacctttttaaaaaatctaaatattaaaggCTTTGAAGTGTTTATGATGAGCGTTAAACATGTCTTGTGAAAAGAGTCcatcatttttacaaatataagtgaacatgaacatttaaaaccttaagaattgtgttgtttcaactcattttaaataagttcttTGAAGAGGCAGCAGAAGTGCTTTGTTGAGGGTGCTGCGTGTACCTCCAGCTCATGTCAGGAGAccttaaaacacaaaagaagatattttgaagaatgctgaaaacatgtaagcagggcttaatttgtgccggaacacaccGGATCCATCAGTTCCCCCCACTGCTCTCCACTATCGTGCGCAGCGCCTCtccatcctcgggtaacatgccggatccataaccccgatctgttccgggacctcgcaattcacaaatgaaGAACTGCATATAACCAGTGACTTCCATAGTAGCAGAAACAAAAACTGtggaggtcagtggttacaggacttcagcattcttcaaaatatcttcttttgtgtttaaaagaaccAAGAAGTTCATAAAGGTTTGGATCCACTCCAGTGCATTTACATTTtagggtgaaccatccctttaaggcAGCGGTGTCTAaagctcagtcctggagggccggtctcctgcagagtttagctccaacctgcttcaacacacctgccagaatgTTTCTAGTGTatccagtaagagcttgattatctgcgtcaggtgtgtttgattagggttggagctaaactctccagcacactggccctccaggaccgagtgtgttCTGCGAGTTAATCTGCTGATGTTTTGGAAATCTTCTGATTCTGTTCTGACACAGCGGGTCCTGCTCTGATGATTCTGATTGGGCGATATATGCTTAGCCACGCTCCTTtaacctggggtgctgaaaaagtggtatggtgcagttcggtatgccttttgacagtggaaacgactATAAAAGCTTTACCGTACCGTACTTtagcactcagtggaaacgggccattagttcGCTGTGAGTGAAAGATGAGAGGCGGAGCTCGAAAATAAACCCGCCccctttttaatattttaattaagtttaaaatGCATTATCATACTTAACAGATTAATGAAAGAAATGCTTTGGGAAACCCTGTGTAACATGATCTGTTTTGTCTATATACACACTTCTGTTCATAATCAAAACTGTAACTGTCTGTTGAATAGAGAATCAGTCTGTCAGGAGTGTTTCTGACTGATGCTTTTAAAACCTCTTGAACTCTTAGTGAATgatttatttgctttaattaatGCCTTTACTGATTGTGGTTGGTTTCTTCACACTGAATGCGTGAGAGTGCAGACGGTTGACTGAGTGTCTAGAGACTAGTCAATGCTGTTATCTAACACAAACATGATTTTGAGCACGAGTCGCTTTAAGCAGAGACAGGGGCAGCTCTACTTTTGGAAAAGCCCATTTTTATCAtgtacaaagctgtaaatgtctGTAGGTCGCATCGATTGTACACACAAATCTTTTGGGTAATCCTGATAGCTGTCGACATTATGATATTCTAATAAATCTTTTGCCATAAACA

Function

symbol description
grk1a Enables rhodopsin kinase activity. Predicted to be involved in protein phosphorylation and regulation of signal transduction. Predicted to act upstream of or within several processes, including phosphorylation; regulation of rhodopsin mediated signaling pathway; and visual perception. Predicted to be active in cytoplasm. Is expressed in epiphysis; eye; retinal photoreceptor layer; and retinal rod cell. Human ortholog(s) of this gene implicated in Oguchi disease-2 and night blindness. Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

GO:

id name namespace
GO:0022400 regulation of rhodopsin mediated signaling pathway biological_process
GO:0007601 visual perception biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0007165 signal transduction biological_process
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0050254 rhodopsin kinase activity molecular_function
GO:0004703 G protein-coupled receptor kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050823-1 Enables rhodopsin kinase activity. Predicted to be involved in protein phosphorylation and regulation of signal transduction. Predicted to act upstream of or within several processes, including phosphorylation; regulation of rhodopsin mediated signaling pathway; and visual perception. Predicted to be active in cytoplasm. Is expressed in epiphysis; eye; retinal photoreceptor layer; and retinal rod cell. Human ortholog(s) of this gene implicated in Oguchi disease-2 and night blindness. Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

Ensembl:

ensembl_id ENSDARG00000058803

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000033 True 4056 mRNA 0.48 7 245076 258138

Neighbor

gene id symbol gene type direction distance location
XLOC_000015 tfdp1b coding upstream 1278 227241 ~ 243798 (+)
XLOC_000014 tmco3 coding upstream 19939 218524 ~ 225137 (+)
XLOC_000013 lamp1a coding upstream 62818 176583 ~ 182258 (+)
XLOC_000012 cul4a coding upstream 77678 157793 ~ 167398 (+)
XLOC_000011 NA coding upstream 87794 156792 ~ 157282 (+)
XLOC_000017 cenpe coding downstream 1901 260039 ~ 296057 (+)
XLOC_000018 NA coding downstream 97343 355481 ~ 358562 (+)
XLOC_000019 tpp2 coding downstream 160731 418869 ~ 443759 (+)
XLOC_000020 blzf1 coding downstream 236159 494297 ~ 505620 (+)
XLOC_000021 txnl4b coding downstream 255848 513986 ~ 518076 (+)
XLOC_000024 dre-mir-155 non-coding downstream 318306 576444 ~ 576521 (+)
XLOC_000026 NA non-coding downstream 536838 794976 ~ 911551 (+)
XLOC_000028 NA non-coding downstream 757674 1015812 ~ 1033638 (+)
XLOC_000029 CR450787.2 non-coding downstream 960553 1218691 ~ 1218805 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000299_06185794_06195015 GRK1A, GRK1 coding CI01000299 null 6185488 ~ 6195015 (-)