XLOC_016750 (adcy8)


Basic Information

Item Value
gene id XLOC_016750
gene name adcy8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 42776224 ~ 42871286 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00032849
GAGCGCCTGGTGTTGTCTGTGCTGCCGCGCTTCGTTGTGCTGGAGATGATTAACGACATGACCAACGTGGAGGACGAGACCCTACAGCATCAGTTTCACCGGATCTACATCCACCGCTATGAGAACGTGAGTATTCTCTTTGCTGACGTGAAGGGCTTCACCAATCTTTCAACCACACTCTCCGCTCAGGAACTTGTTCGAATGCTCAACGAACTCTTTGCACGATTCGACCGACTGGCACACGAGCATCATTGTCTGAGGATCAAGATACTGGGGGATTGTTATTATTGTGTTTCTGGCCTTCCTGAGCCTCGGCCAGATCATGCTCACTGCTGCGTTGAGATGGGCCTCAGCATGATCAAAACCATCAGATACGTGCGCTCTCGTACAAAACATGACATAGACATGCGCATTGGCATCCACTCTGGCTCGGTTCTGTGCGGAGTTCTTGGTTTGCGGAAATGGCAGTTTGACGTGTGGTCTTGGGATGTGGACATAGCCAACAAACTGGAGTCGGGGGGAATACCTGGGAGGATCCACATCTCTAAAGCGGCTCTCGACTGTCTGAACGGAGATTACGAGGTGGAGGAGGGTCATGGTAAGGACCGTAATGACTTCCTGCGCAGGCATAACATCGAGACCTTCCTGATCAAGCAGCCGGAGGAGAGCTTGCTTACACTACCCGAGGACATCATGAGAGACTCCACCAACCAATCAGATCACAGGACCTCCAACACTTCCTTCACAGAGGGAACGTGGAGCCCTGAACTTCCCTTCCATAACATAGTGGGCAAGCAGAATACTCTGGCTGCGCTCACACGTCACTCCATTAACCTGCTCCCCAACCACCTGGCTCAAGCCCTGCATGTGCGCGCCGGCTCACAGGAAATTAACGCTCGCATGCAGAGCACCATCGCCCTGCGCAGCGGGGACAAGCTCCGCCAAGAACATATCTCCCCCTTCTCTCTCACCTTTAGAGAAGCACTGCTGGAGCACAAGtattcccAGATGAGAGATGAGGTGTTTAAGTCAAATCTAGTGTGTGCCTTCATTGTTCTCTTCTTCATCACTGGAATACAGAGCTTACTTCCCTCTGCAAGGATGGTAACGATGCTGATCCAGTTCTCTGTCCTCATCCTGCTGCACTGCTGCCTTGTTGTTGTGACCACTGCCGAGGATTACAAGTGTTTGCCGCTGGTTTTGCGTAAAGCGTGCTGCTGGGTGAATGAAACCTACGCCGCGCGGAACGTCGTCATCTTCCTGTCCATCCTTATTAACTTTCTGGCTGCCATGATCAACATACTTTGGTGTGATTTTGATAAATCGGGCTCATTCAGGAACCAGACGTTTAATGCATCCGCCTCAATCCCAGATATCTGCTTCTACCCAGAGTATTTCGTGTTTACCGGAGTGCTGGCGATGGTGACCTGTGCGGTTTTTCTCCGACTGAATTCAGTTTTGAAGTTGGCGATCCTTCTCATCATGATTGCCATCTATGCTGTCCTGACCGAGGCCTTTTACACGCCGTTGTTCATTCGATACGACACGCTGACTCTCAATCAGAGCAAAAGCTTCCTGGGGACCAAGGAGACGTCTCTGCTTCTCATGGCCATGTTCCTCCTAGCTGTGTTTTACCACGGCCAGCAGctGGAATATACGGCTCGTCTGGACTTCCTATGGCGTGTGCAGGCGAAGGAAGAGATAAATGAGATGCGAGAGCTGCGTGAGCACAATGAGAACATGCTCCGGAACATTCTTCCCAGCCACGTCGCTCGCCATTTCCTGGAGAAAGACAGAGACAATGAGGAGCTCTACTCGCAGTCATATGACACGGTGGGAGTGATGTTCGCCTCCATTCCAGGCTTTGCTGATTTTTACTCTCAGACGGAGATGAATAACCAGGGCGTGGAGTGTTTGCGGCTGCTCAACGAGATCATCGCTGATTTTGATGAGCTGCTGGGGGAGGAAAGATTTCAGGACATCGAGAAGATTAAGACCATCGGCAGCACGTACATGGCTGTGTCAGGACTGTCTCCTGAGAAACAgcaatgtGAGGATAAATGGGGGCATCTGTGTGCGCTGGCCGATTTCGCCATTGCTCTGAATGAAAGCATTCAGGAGATCAACAAGCATTCGTTTAACAACTTCCAGCTCAGAATCGGTATGGCACACGGCTCTGTGGTGGCTGGAGTGATCGGCGCTAAAAAGCCACAGTACGATATCTGGGGGAAGACGGTCAATCTGGCGAGTCGCATGGACAGCACAGGCGTCAGCGGTAAGATCCAGCTCCCAGAAGAGACTTATGCCATTCTGAACGAGCGCGGCTTTGCCTTCGAGTACCGTGGTGAGATCTACGTGAAGGGCATCAGTGAGCAGGAAGGAAAGATCCGCACACACTTCATGATAGGCCGCGTGCAGCCCAACCCGCTCATCCTGCAGCCCAGGAAGCTCACGGGCCAGTACTCGCTGGCCGCCGTGGTGCTCGGCCTGGTGCAGTCCCTCAACCGGCAGAAACAGAAACAAATCCTCAACGAAAACAACAACTCAGGCATCATGAAGGGCCACTACAACCGCAGGACTCTGCTGGCGCCGGGCGGCTCGGACACCAGTCATGCCGAGGTCACGGACAAAAGCGATCTGGCCTAA
>TCONS_00032850
aggctgaagtttgagaaggaaaaccaacaacagGAGCGCCTGGTGTTGTCTGTGCTGCCGCGCTTCGTTGTGCTGGAGATGATTAACGACATGACCAACGTGGAGGACGAGACCCTACAGCATCAGTTTCACCGGATCTACATCCACCGCTATGAGAACGTGAGTATTCTCTTTGCTGACGTGAAGGGCTTCACCAATCTTTCAACCACACTCTCCGCTCAGGAACTTGTTCGAATGCTCAACGAACTCTTTGCACGATTCGACCGACTGGCACACGAGCATCATTGTCTGAGGATCAAGATACTGGGGGATTGTTATTATTGTGTTTCTGGCCTTCCTGAGCCTCGGCCAGATCATGCTCACTGCTGCGTTGAGATGGGCCTCAGCATGATCAAAACCATCAGATACGTGCGCTCTCGTACAAAACATGACATAGACATGCGCATTGGCATCCACTCTGGCTCGGTTCTGTGCGGAGTTCTTGGTTTGCGGAAATGGCAGTTTGACGTGTGGTCTTGGGATGTGGACATAGCCAACAAACTGGAGTCGGGGGGAATACCTGGGAGGATCCACATCTCTAAAGCGGCTCTCGACTGTCTGAACGGAGATTACGAGGTGGAGGAGGGTCATGGTAAGGACCGTAATGACTTCCTGCGCAGGCATAACATCGAGACCTTCCTGATCAAGCAGCCGGAGGAGAGCTTGCTTACACTACCCGAGGACATCATGAGAGACTCCACCAACCAATCAGATCACAGGACCTCCAACACTTCCTTCACAGAGGGAACGTGGAGCCCTGAACTTCCCTTCCATAACATAGTGGGCAAGCAGAATACTCTGGCTGCGCTCACACGTCACTCCATTAACCTGCTCCCCAACCACCTGGCTCAAGCCCTGCATGTGCGCGCCGGCTCACAGGAAATTAACGCTCGCATGCAGAGCACCATCGCCCTGCGCAGCGGGGACAAGCTCCGCCAAGAACATATCTCCCCCTTCTCTCTCACCTTTAGAGAAGCACTGCTGGAGCACAAGtattcccAGATGAGAGATGAGGTGTTTAAGTCAAATCTAGTGTGTGCCTTCATTGTTCTCTTCTTCATCACTGGAATACAGAGCTTACTTCCCTCTGCAAGGATGGTAACGATGCTGATCCAGTTCTCTGTCCTCATCCTGCTGCACTGCTGCCTTGTTGTTGTGACCACTGCCGAGGATTACAAGTGTTTGCCGCTGGTTTTGCGTAAAGCGTGCTGCTGGGTGAATGAAACCTACGCCGCGCGGAACGTCGTCATCTTCCTGTCCATCCTTATTAACTTTCTGGCTGCCATGATCAACATACTTTGGTGTGATTTTGATAAATCGGGCTCATTCAGGAACCAGACGTTTAATGCATCCGCCTCAATCCCAGATATCTGCTTCTACCCAGAGTATTTCGTGTTTACCGGAGTGCTGGCGATGGTGACCTGTGCGGTTTTTCTCCGACTGAATTCAGTTTTGAAGTTGGCGATCCTTCTCATCATGATTGCCATCTATGCTGTCCTGACCGAGGCCTTTTACACGCCGTTGTTCATTCGATACGACACGCTGACTCTCAATCAGAGCAAAAGCTTCCTGGGGACCAAGGAGACGTCTCTGCTTCTCATGGCCATGTTCCTCCTAGCTGTGTTTTACCACGGCCAGCAGctGGAATATACGGCTCGTCTGGACTTCCTATGGCGTGTGCAGGCGAAGGAAGAGATAAATGAGATGCGAGAGCTGCGTGAGCACAATGAGAACATGCTCCGGAACATTCTTCCCAGCCACGTCGCTCGCCATTTCCTGGAGAAAGACAGAGACAATGAGGAGCTCTACTCGCAGTCATATGACACGGTGGGAGTGATGTTCGCCTCCATTCCAGGCTTTGCTGATTTTTACTCTCAGACGGAGATGAATAACCAGGGCGTGGAGTGTTTGCGGCTGCTCAACGAGATCATCGCTGATTTTGATGAGCTGCTGGGGGAGGAAAGATTTCAGGACATCGAGAAGATTAAGACCATCGGCAGCACGTACATGGCTGTGTCAGGACTGTCTCCTGAGAAACAgcaatgtGAGGATAAATGGGGGCATCTGTGTGCGCTGGCCGATTTCGCCATTGCTCTGAATGAAAGCATTCAGGAGATCAACAAGCATTCGTTTAACAACTTCCAGCTCAGAATCGGTATGGCACACGGCTCTGTGGTGGCTGGAGTGATCGGCGCTAAAAAGCCACAGTACGATATCTGGGGGAAGACGGTCAATCTGGCGAGTCGCATGGACAGCACAGGCGTCAGCGGTAAGATCCAGCTCCCAGAAGAGACTTATGCCATTCTGAACGAGCGCGGCTTTGCCTTCGAGTACCGTGGTGAGATCTACGTGAAGGGCATCAGTGAGCAGGAAGGAAAGATCCGCACACACTTCATGATAGGCCGCGTGCAGCCCAACCCGCTCATCCTGCAGCCCAGGAAGCTCACGGGCCAGTACTCGCTGGCCGCCGTGGTGCTCGGCCTGGTGCAGTCCCTCAACCGGCAGAAACAGAAACAAATCCTCAACGAAAACAACAACTCAGGCATCATGAAGGGCCACTACAACCGCAGGACTCTGCTGGCGCCGGGCGGCTCGGACACCAGTCATGCCGAGGTCACGGACAAAAGCGATCTGGCCTAA
>TCONS_00032851
GGAGGTCTTCTCTCATTCTTCTATGTAAACAGCCTTTGACAGTGCTAGTGCTACGCTACAGAAAGACTCTGGCTGCGCTCACACGTCACTCCATTAACCTGCTCCCCAACCACCTGGCTCAAGCCCTGCATGTGCGCGCCGGCTCACAGGAAATTAACGCTCGCATGCAGAGCACCATCGCCCTGCGCAGCGGGGACAAGCTCCGCCAAGAACATATCTCCCCCTTCTCTCTCACCTTTAGAGAAGCACTGCTGGAGCACAAGtattcccAGATGAGAGATGAGGTGTTTAAGTCAAATCTAGTGTGTGCCTTCATTGTTCTCTTCTTCATCACTGGAATACAGAGCTTACTTCCCTCTGCAAGGATGGTAACGATGCTGATCCAGTTCTCTGTCCTCATCCTGCTGCACTGCTGCCTTGTTGTTGTGACCACTGCCGAGGATTACAAGTGTTTGCCGCTGGTTTTGCGTAAAGCGTGCTGCTGGGTGAATGAAACCTACGCCGCGCGGAACGTCGTCATCTTCCTGTCCATCCTTATTAACTTTCTGGCTGCCATGATCAACATACTTTGGTGTGATTTTGATAAATCGGGCTCATTCAGGAACCAGACGTTTAATGCATCCGCCTCAATCCCAGATATCTGCTTCTACCCAGAGTATTTCGTGTTTACCGGAGTGCTGGCGATGGTGACCTGTGCGGTTTTTCTCCGACTGAATTCAGTTTTGAAGTTGGCGATCC
>TCONS_00032852
GAGCATCATTGTCTGAGGATCAAGATACTGGGGGATTGTTATTATTGTGTTTCTGGCCTTCCTGAGCCTCGGCCAGATCATGCTCACTGCTGCGTTGAGATGGGCCTCAGCATGATCAAAACCATCAGATACGTGCGCTCTCGTACAAAACATGACATAGACATGCGCATTGGCATCCACTCTGGCTCGGTTCTGTGCGGAGTTCTTGGTTTGCGGAAATGGCAGTTTGACGTGTGGTCTTGGGATGTGGACATAGCCAACAAACTGGAGTCGGGGGGAATACCTGGGAGGATCCACATCTCTAAAGCGGCTCTCGACTGTCTGAACGGAGATTACGAGGTGGAGGAGGGTCATGGTAAGGACCGTAATGACTTCCTGCGCAGGCATAACATCGAGACCTTCCTGATCAAGCAGCCGGAGGAGAGCTTGCTTACACTACCCGAGGACATCATGAGAGACTCCACCAACCAATCAGATCACAGGACCTCCAACACTTCCTTCACAGAGGGAACGTGGAGCCCTGAACTTCCCTTCCATAACATAGTGGGCAAGCAGAATtattcccAGATGAGAGATGAGGTGTTTAAGTCAAATCTAGTGTGTGCCTTCATTGTTCTCTTCTTCATCACTGGAATACAGAGCTTACTTCCCTCTGCAAGGATGGTAACGATGCTGATCCAGTTCTCTGTCCTCATCCTGCTGCACTGCTGCCTTGTTGTTGTGACCACTGCCGAGGATTACAAGTGTTTGCCGCTGGTTTTGCGTAAAGCGTGCTGCTGGGTGAATGAAACCTACGCCGCGCGGAACGTCGTCATCTTCCTGTCCATCCTTATTAACTTTCTGGCTGCCATGATCAACATACTTTGGTGTGATTTTGATAAATCGGGCTCATTCAGGAACCAGACGTTTAATGCATCCGCCTCAATCCCAGATATCT

Function

symbol description
adcy8 Predicted to enable adenylate cyclase activity. Acts upstream of or within axon midline choice point recognition and retinal ganglion cell axon guidance. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in retinal ganglion cell. Orthologous to human ADCY8 (adenylate cyclase 8).

GO:

id name namespace
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0031290 retinal ganglion cell axon guidance biological_process
GO:0016199 axon midline choice point recognition biological_process
GO:0006171 cAMP biosynthetic process biological_process
GO:0009190 cyclic nucleotide biosynthetic process biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004016 adenylate cyclase activity molecular_function
GO:0016829 lyase activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016849 phosphorus-oxygen lyase activity molecular_function

KEGG:

id description
ko00230 Purine metabolism
ko04015 Rap1 signaling pathway
ko04371 Apelin signaling pathway
ko04020 Calcium signaling pathway
ko04072 Phospholipase D signaling pathway
ko04024 cAMP signaling pathway
ko04022 cGMP-PKG signaling pathway
ko04114 Oocyte meiosis
ko04540 Gap junction
ko04611 Platelet activation
ko04062 Chemokine signaling pathway
ko04911 Insulin secretion
ko04923 Regulation of lipolysis in adipocytes
ko04912 GnRH signaling pathway
ko04913 Ovarian steroidogenesis
ko04915 Estrogen signaling pathway
ko04914 Progesterone-mediated oocyte maturation
ko04921 Oxytocin signaling pathway
ko04926 Relaxin signaling pathway
ko04935 Growth hormone synthesis, secretion and action
ko04918 Thyroid hormone synthesis
ko04928 Parathyroid hormone synthesis, secretion and action
ko04916 Melanogenesis
ko04925 Aldosterone synthesis and secretion
ko04927 Cortisol synthesis and secretion
ko04261 Adrenergic signaling in cardiomyocytes
ko04270 Vascular smooth muscle contraction
ko04970 Salivary secretion
ko04971 Gastric acid secretion
ko04972 Pancreatic secretion
ko04976 Bile secretion
ko04724 Glutamatergic synapse
ko04727 GABAergic synapse
ko04725 Cholinergic synapse
ko04720 Long-term potentiation
ko04723 Retrograde endocannabinoid signaling
ko04742 Taste transduction
ko04750 Inflammatory mediator regulation of TRP channels
ko04211 Longevity regulating pathway
ko04213 Longevity regulating pathway - multiple species
ko04713 Circadian entrainment
ko04714 Thermogenesis
ko05200 Pathways in cancer
ko05207 Chemical carcinogenesis - receptor activation
ko05166 Human T-cell leukemia virus 1 infection
ko05163 Human cytomegalovirus infection
ko05032 Morphine addiction
ko05414 Dilated cardiomyopathy
ko04934 Cushing syndrome
ko01522 Endocrine resistance

ZFIN:

id description
ZDB-GENE-070912-197 Predicted to enable adenylate cyclase activity. Acts upstream of or within axon midline choice point recognition and retinal ganglion cell axon guidance. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in retinal ganglion cell. Orthologous to human ADCY8 (adenylate cyclase 8).

Ensembl:

ensembl_id ENSDARG00000031783

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00032849 False 2646 mRNA 0.52 16 42776224 42864472
TCONS_00032850 False 2679 mRNA 0.52 18 42776224 42871286
TCONS_00032851 False 738 mRNA 0.50 6 42814942 42827336
TCONS_00032852 True 937 mRNA 0.50 6 42815227 42843797

Neighbor

gene id symbol gene type direction distance location
XLOC_016749 NA coding downstream 4246 42719037 ~ 42771978 (-)
XLOC_016745 NA coding downstream 27562 42665902 ~ 42748662 (-)
XLOC_016748 NA coding downstream 58498 42713799 ~ 42717726 (-)
XLOC_016747 NA coding downstream 65795 42708669 ~ 42710429 (-)
XLOC_016744 myo10 coding downstream 70940 42605252 ~ 42705284 (-)
XLOC_016751 NA coding upstream 64595 42935881 ~ 42936238 (-)
XLOC_016752 oc90 coding upstream 71266 42942552 ~ 42960353 (-)
XLOC_016753 BX511268.2 coding upstream 90942 42962228 ~ 42962344 (-)
XLOC_016754 NA coding upstream 91576 42962862 ~ 42978612 (-)
XLOC_016755 NA coding upstream 109918 42981204 ~ 42986970 (-)
XLOC_016746 NA non-coding downstream 97842 42678023 ~ 42678382 (-)
XLOC_016763 NA non-coding upstream 506816 43378102 ~ 43379093 (-)

Expression


Co-expression Network