XLOC_016756 (kcnq3)


Basic Information

Item Value
gene id XLOC_016756
gene name kcnq3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 43001512 ~ 43010396 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00032857
TCAGAAGTTGAGTTTGCTGGATCGTGTTCGTCTGTCGACTCCGAGGCCATCCACAGTGAGAGCCCGCGTCATGATGCCTGCTGCCAATCCTGAAAGTGTGCCAGGGAACTGTGGGCCGGCGGAGGCCATTGAAGAGAGTCCATCAAAAGAGGGCAAACCAGCGGGATTCAGTAACAGAGAGAGATTTAGAACTGCTTTCAGAATGAAGGCCTACGCCCTGAGACAGAGCTCTGAGGATACTGGTGGTCTTCCTGATCCCACCCCTGAGGAGAAGGGCTTCCCGCCTGATATACTGCTGGAGGAGATGATTCCCACTCTCAAACTAGTGATACGAGCACTGCGGATTATAATGTTCCTGCTGAATAAGAAGCGTTTTAAGGAGACTCTGAGGCCATATGATGTGAAGGATGTGATTGAACAGTATTCTGCTGGACACCTCGACATGCTCACCAGAATCAAATATCTGCAGACACGGTTAGATCTGATTCTGACTCCTGGACCAACTCTGACTCCAAAACACAAGAAGCCCCAGAAAACTCCATTTCCGTACCCATCCCAGCAGTCTCCTAGACAGGAGTCATACCTTGCCAAAACAAGCCTGCCAGATCCCGAAGACCAAAGCATGATGGGTAGATTTGTGCGGGTGGAGAGACAGGTGGAAGACATGGAGAAGAAACTGGACTTCCTGGTGGACATGCATATGCAACATGACTTCACAGGCCCGGGTCACATGACCATGGAGCGCTGCGACCCCACATTAACCGTTAGCGTAGCGGGCGACCGCGTTTACTGCAGCTACGGCCCCCCGCTACACAACACCCCATACTACACACATCCGCCGAGACCGACCGTCCTGCCAATTAGCCCACTGCCAAGCCACTCGCCATCCTCCAACGTCAGCCAAACTGGTGGCCATCGGGTCGGGACACCACTCTCGCTCCTGTCGGTCACTCACGAGGAGCTGGAGCGGTCACCCAGCGGATTTAGCATCTCAGCGGAGAAAGAAGAGGTCACGGGGAAGGCCTCGGGGTTAACAGCAGGGTCGAGTTGGGGCCGTGACCGCCGATATTTAGCCGAGGGAGAGACGGATACAGACACTGATCCCTTTACACCCAGCGGACCTGTTCCTCCATCCTCCACCGGAGATGGCTTTCAGTCGGACGGAGCGTGGGGTACACCACCCTAA

Function

symbol description
kcnq3 Predicted to enable calmodulin binding activity and delayed rectifier potassium channel activity. Acts upstream of or within chemical synaptic transmission. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in axon initial segment. Predicted to be integral component of membrane. Is expressed in central nervous system; heart; and inner ear. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3).

GO:

id name namespace
GO:0071805 potassium ion transmembrane transport biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:0043194 axon initial segment cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0005516 calmodulin binding molecular_function
GO:0005216 ion channel activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0005251 delayed rectifier potassium channel activity molecular_function
GO:0005267 potassium channel activity molecular_function

KEGG:

id description
ko04725 Cholinergic synapse
ko04040 Ion channels

ZFIN:

id description
ZDB-GENE-070912-301 Predicted to enable calmodulin binding activity and delayed rectifier potassium channel activity. Acts upstream of or within chemical synaptic transmission. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in axon initial segment. Predicted to be integral component of membrane. Is expressed in central nervous system; heart; and inner ear. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3).

Ensembl:

ensembl_id ENSDARG00000060085

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00032857 True 1186 mRNA 0.55 6 43001512 43010396

Neighbor

gene id symbol gene type direction distance location
XLOC_016755 NA coding downstream 14542 42981204 ~ 42986970 (-)
XLOC_016754 NA coding downstream 22900 42962862 ~ 42978612 (-)
XLOC_016753 BX511268.2 coding downstream 39168 42962228 ~ 42962344 (-)
XLOC_016752 oc90 coding downstream 41159 42942552 ~ 42960353 (-)
XLOC_016751 NA coding downstream 65274 42935881 ~ 42936238 (-)
XLOC_016757 kcnq3 coding upstream 3983 43014379 ~ 43083755 (-)
XLOC_016758 lrrc6 coding upstream 87841 43098237 ~ 43124747 (-)
XLOC_016759 ftr13 coding upstream 117966 43128362 ~ 43130930 (-)
XLOC_016760 ftr14 coding upstream 120751 43131147 ~ 43135700 (-)
XLOC_016761 ftr12 coding upstream 134542 43144938 ~ 43151358 (-)
XLOC_016749 NA non-coding downstream 229534 42719037 ~ 42771978 (-)
XLOC_016763 NA non-coding upstream 367706 43378102 ~ 43379093 (-)
XLOC_016764 CABZ01058723.1 non-coding upstream 499106 43509502 ~ 43517018 (-)
XLOC_016766 NA non-coding upstream 556749 43567145 ~ 43571760 (-)
XLOC_016770 NA non-coding upstream 619357 43629753 ~ 43630083 (-)
XLOC_016786 BX323035.1 non-coding upstream 1512460 44522856 ~ 44524381 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G358298 NA non-coding CI01000152 null 448933 ~ 456713 (+)